Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review by Kunzah A. Syed, Elham Afghani, Kelly J. Lafaro

“…Fortunately, endoscopy-based diagnostic and therapeutic techniques like endoscopic ultrasound with fine needle aspiration, confocal endomicroscopy, through-the-needle biopsy, contrast-enhanced endoscopic ultrasound, ablation, and pancreatoscopy have enabled increasingly accurate diagnoses of PCLs. …”
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Multifocal Gastric Neoplasia after Recurrent Laser Therapy for the Watermelon Stomach by Charles N Bernstein, Norman Pettigrew, Kenneth K Wang, Howard Greenberg, Jeremy Lipschitz

“…Repeated laser therapy has become an accepted therapeutic approach in the treatment of watermelon stomach, and to date no important negative sequelae have been reported. …”
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Management of Anticoagulation for Portal Vein Thrombosis in Individuals with Cirrhosis: A Systematic Review by Geneviève Huard, Marc Bilodeau

“…We herein review the current knowledge on that topic in order to highlight the advantages and disadvantages of the currently proposed therapeutic attitudes in face of the diagnosis of PVT in individuals with cirrhosis.…”
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Identification of Two Novel Immune Subtypes Characterized by Distinct Prognosis and Tumor Microenvironment in Osteosarcoma by Shunhan Yao, Meiling Deng, Xiaojing Du, Qingfeng Chen, Rongzhi Huang

“…In recent years, its therapeutic effect and prognostic survival are dissatisfactory. …”
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The South African guidelines on enuresis: 2024 update by A Adam, A Badenhorst, F Claassen, T de Maayer, M Fockema, J Fredericks, E Gottlich, J John, N Lala, J Lazarus, S Leahy, H N Lourens, S Maharaj, K M Mathabe, E M Moshokoa, S B A Mutambirwa, K L Petersen, M B Radzuma, A van der Merwe, I van Heerden, C A Zietsman, F Alyami, A Deshpande, G H H Smith

“…The guideline provides recommendations and suggestions for various therapeutic options for enuresis available in South Africa (SA). …”
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Assessing the health implications of anticholinergic drugs in older people by Mariangela Boccardi, Virginia Boccardi

“…While anticholinergic medications provide therapeutic benefits, their use in older adults requires careful evaluation due to these considerable risks. …”
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The woman and her inner dialogue: How Positive Psychotherapy transforms psychosomatic challenges into strength by Elena Drazheva, Stiliyana Stamova

“…The case study highlights the importance of an empathic and structured therapeutic approach when dealing with psychosomatic symptoms. …”
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Peroxisome Proliferator-Activated Receptors and Acute Lung Injury by Rosanna Di Paola, Salvatore Cuzzocrea

“…This review will outline the anti-inflammatory effects of PPARs and PPAR ligands and discuss their potential therapeutic effects in animal models of inflammatory lung disease.…”
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MDM4 Isoform Expression in Melanoma Supports an Oncogenic Role for MDM4-A by Abdullah Alatawi, SoonJye Kho, Michael P. Markey

“…These changes in splicing must be considered in the design of therapeutic inhibitors of the MDM2/4 proteins for melanoma.…”
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Advances and prospects of cell-penetrating peptides in tumor immunotherapy by Di Yang, Baorui Liu, Huizi Sha

“…Abstract Cell-penetrating peptides (CPPs) have been shown to have superior material transport ability because poor infiltration of activated lymphocytes into tumors is one of the crucial factors limiting the therapeutic effect of tumor immunotherapy. Numerous studies have investigated the potential application of CPPs in tumor immunotherapy. …”
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Pathophysiology of Resistant Hypertension: The Role of Sympathetic Nervous System by Costas Tsioufis, Athanasios Kordalis, Dimitris Flessas, Ioannis Anastasopoulos, Dimitris Tsiachris, Vasilios Papademetriou, Christodoulos Stefanadis

“…The further investigation and understanding of the mechanisms leading to SNS activation could reveal novel therapeutic targets and expand our treatment options in the challenging management of RH.…”
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Incidental Laparoscopic Discovery of an Intraperitoneal Plastic Catheter 16 Years after an Unsafe Abortion: A Case Report from the Gynecologic, Obstetric, and Pediatric Hospital of... by Ngandji Andre, Ngo Um Meka Esther Juliette, Fokom Joel, Wandji Brigitte, Foumane Pascal

“…This is a rare clinical finding which is of therapeutic and diagnostic importance. To the best of our knowledge, a single similar case has been reported so far in the literature.…”
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Advanced Epithelioid Malignant Peripheral Nerve Sheath Tumor Showing Complete Response to Combined Surgery and Chemotherapy: A Case Report by Tomohiro Minagawa, Ryuta Shioya, Chigusa Sato, Ryuji Shichinohe, Go Yasui, Kohsuke Ishikawa, Hiroko Takahashi

“…Reports of approximately 40 cases are available in the English literature; however, most reports addressed clinicopathological features rather than therapeutic procedures or clinical courses. We describe a case of a 62-year-old male with an epithelioid MPNST of the left foot. …”
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The Fate of Allogeneic Pancreatic Islets following Intraportal Transplantation: Challenges and Solutions by Xinyu Li, Qiang Meng, Lei Zhang

“…Pancreatic islet transplantation as a therapeutic option for type 1 diabetes mellitus is gaining widespread attention because this approach can restore physiological insulin secretion, minimize the risk of hypoglycemic unawareness, and reduce the risk of death due to severe hypoglycemia. …”
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Key Signaling Pathways Regulate the Development and Survival of Auditory Hair Cells by Yao Liu, Mei Wei, Xiang Mao, Taisheng Chen, Peng Lin, Wei Wang

“…The molecular interactions of these signaling pathways play an important role in the survival of HCs, which may provide a theoretical basis and possible therapeutic interventions for the treatment of hearing loss.…”
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Regulation of Neutrophil Survival/Apoptosis by Mcl-1 by Eric Milot, János G. Filep

“…This paper will focus on multiple levels of control of Mcl-1 expression and function and will discuss targeting Mcl-1 as a potential therapeutic strategy to enhance the resolution of inflammation through accelerating neutrophil apoptosis.…”
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Research Progress in Short-Chain Fatty Acid Modulation of the Gut-Bone Axis in Bone Metabolism by ZHANG Xuan, YANG Xue, LI Xinke, MENG Lu, WANG Jiaqi, ZHENG Nan

“…Seeking safe and effective therapeutic interventions is of utmost importance. The modulation of bone metabolism by the gut microbiota and their metabolites has emerged as a focal area of research. …”
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Mechanistic insights into connexin-mediated neuroglia crosstalk in neurodegenerative diseases by Simona Denaro, Simona D’Aprile, Nunzio Vicario, Rosalba Parenti

“…This review explores mechanistic insights of Cxs-mediated intercellular communication in the progression of neurodegenerative diseases and discusses the therapeutic potential of targeting Cxs to restore cellular homeostasis.…”
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Alternative Splicing: Emerging Roles in Anti-Aging Strategies by Lingyue Gao, Rong Jia

“…In this review, we will summarize the latest research progress on alternative splicing in aging and cellular senescence, discuss the roles and regulatory mechanisms of alternative splicing during aging, and then excavate existing and potential approaches to anti-aging by controlling alternative splicing. Novel therapeutic breakthroughs concerning aging and senescence entail a further understanding of regulating alternative splicing mechanically and accurately.…”
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Physiotherapy and Nutrition: Two Unavoidable Therapies in the Treatment of Chronic non-communicable Diseases by Ismaray Sacerio González, Lourdes Elena Duany Badell, Lenia Marín Medina

“…Only an additional intake of natural nutrients is not enough, it is necessary to complement it with other therapeutic tools within physiotherapy. People suffering from chronic diseases have transformations in eating practices, created by the underlying disease, so it is important to vary dietary habits in order to regain health. …”
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