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5321
Medicinal, nutritional, and nutraceutical potential of Sparassis crispa s. lat.: a review
Published 2022-05-01“…It is recognized for therapeutic value because of the high β-glucan content in the basidiomes. …”
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5322
Lipid droplets in central nervous system and functional profiles of brain cells containing lipid droplets in various diseases
Published 2025-01-01“…Additionally, we also emphasize the paradoxical role of LDs in post-cerebral ischemia inflammation and explore potential underlying mechanisms, aiming to identify novel therapeutic targets for this disease.…”
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5323
Obesity-Related Chronic Kidney Disease: From Diagnosis to Treatment
Published 2025-01-01“…Finally, we explore emerging therapeutic strategies that offer promise in mitigating this growing global health crisis.…”
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5324
Effects of macrophages in OSCC progression
Published 2025-01-01“…It can provide theoretical basis for the establishment of complex regulatory network centered on macrophages and explore novel therapeutic strategies for OSCC.…”
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5325
Super-enhancers in tumors: unraveling recent advances in their role in Oncogenesis and the emergence of targeted therapies
Published 2025-01-01“…Furthermore, we discuss the current landscape and challenges in developing cancer therapeutic drugs that target super enhancers.…”
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5326
Current status and prospects of traditional Chinese medicine combined with stem cell therapy for chronic kidney disease
Published 2025-01-01“…Therefore, stem cell therapy combined with TCM is expected to provide new therapeutic ideas and measures to solve kidney problems. …”
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5327
The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency
Published 2012-01-01“…Due to its prominent role in regulating metabolism, PTP1B is a promising therapeutic target for the treatment of human obesity and type 2 diabetes. …”
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5328
Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix
Published 2012-01-01“…Malignant primary tumors can be removed surgically, but the cells that migrate, invade, and proliferate at distant organs are often the cells that prove most difficult to target therapeutically. There is growing evidence that host factors outside of the primary tumors are of major importance in the development of metastasis. …”
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5329
Transcranial Magnetic Stimulation for the Treatment of Pharmacoresistant Nondelusional Auditory Verbal Hallucinations in Dementia
Published 2013-01-01“…In the last decades, Transcranial Magnetic Stimulation (TMS) emerged as a valuable therapeutic approach towards several neurological and psychiatric diseases, including AVHs. …”
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5330
Understanding the link between type 2 diabetes mellitus and Parkinson’s disease: role of brain insulin resistance
Published 2025-11-01“…The contribution of type 2 diabetes mellitus and insulin resistance in neurodegeneration in Parkinson’s disease, with emphasis on brain insulin resistance, is extensively discussed in this article and new therapeutic strategies targeting this pathological link are presented and reviewed.…”
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5331
Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement
Published 2020-01-01“…This review is aimed at summarizing the role of TRPC6 on DKD by regulating the podocyte actin cytoskeleton rearrangement, thereby help further broaden our views and understanding on the mechanism of DKD and provide a theoretic basis for exploring new therapeutic targets for DKD patients.…”
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5332
Homeostatic T Cell Proliferation after Islet Transplantation
Published 2013-01-01“…In this review, we will discuss how homeostatic T cell proliferation can support autoimmunity recurrence after islet transplantation and how it can be targeted by new therapeutic approaches.…”
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5333
A human-induced pluripotent stem cell (iPSC) line (SMUSHi006-A) from an ALS patient carrying a mutation c.1126C > T in the FUS gene
Published 2025-02-01“…This research aims not only to establish a disease model for ALS linked to FUS mutations but also to pave the way for potential therapeutic interventions.…”
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5334
Acute Stroke Imaging: Recent Updates
Published 2013-01-01“…Neuroimaging plays a crucial role in early diagnosis and yields essential information regarding tissue integrity, a factor that remains a key therapeutic determinant. Given the widespread public health implications of stroke and central role of neuroimaging in overall management, acute stroke imaging remains a heavily debated, extensively researched, and rapidly evolving subject. …”
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5335
Examining the opinions of senior university students and their actual clients regarding the supervision of practice-based course structured on the Balance model of Positive Psychot...
Published 2025-01-01“… Positive psychotherapy is one of the most comprehensive and effective therapeutic methods in psychoanalytic models. The Balance model of Positive psychotherapy is a key concept that helps not only psychotherapists and clients to detect the problem to plan a route for action but also to build hope for the future life. …”
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5336
Rare Cause for Sudden Right Heart Failure
Published 2010-01-01“…Generally, cardiac malignant tumors are diagnosed at a time-point when therapeutic options are very limited or even postmortem. …”
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5337
Nano theranostics involved in bladder cancer treatment
Published 2023-04-01“…Theranostics, the integration of diagnostic and therapeutic technologies, has emerged as a promising strategy to address these challenges. …”
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5338
Peptide with Dual Roles in Immune and Metabolic Regulation: Liver-Expressed Antimicrobial Peptide-2 (LEAP-2)
Published 2025-01-01“…LEAP-2 alone or the LEAP-2/ghrelin molar ratio showed potential as therapeutic targets for obesity, diabetes, and metabolic disorders. …”
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5339
Virotherapy in Head and Neck Cancer
Published 2024-03-01“…Virotherapy involves the use of genetically modified viruses as therapeutic agents to selectively target and destroy cancer cells while sparing healthy tissues. …”
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5340
The Use of MSK Ultrasound in the Evaluation of Elbow Ulnar Collateral Ligament Injuries
Published 2023-04-01“…By directly visualizing static and dynamic loads to the ligament, physical therapists can gain valuable information about underlying pathology and guide the therapeutic decision-making process. In this sound byte, we will look at how incorporating MSK-US imaging into your patient assessments can provide you with more comprehensive data to make informed clinical decisions when treating UCL injuries in the elbow.…”
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