Patients with Diabetes Complicated by Peripheral Artery Disease: the Current State of Knowledge on Physiotherapy Interventions by Katarzyna Hap, Karolina Biernat, Grzegorz Konieczny

“…Physiotherapy (kinesitherapy combined with different physical therapy agents) in individuals with DM and coexisting PAD may offer an important complementary therapy alternative. Early therapeutic measures can significantly improve patient outcomes, reduce cardiovascular risk, and improve daily life quality. …”
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A brief review on microphthalmia and anophthalmia by Jayasri Periyandavan, Mary Stephen

“…Despite advancements in understanding and management, anophthalmia and microphthalmia remain major causes of childhood blindness, highlighting the ongoing need for research to elucidate underlying mechanisms and develop novel therapeutic strategies.…”
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Imatinib Resistance in Chronic Myeloid Leukemia Associated with a D363G BCR::ABL1 Kinase Domain Mutation by Stephen E. Langabeer, Stuart Macleod, Úna Bhreathnach, Kamal Fadalla

“…Acquired resistance to tyrosine kinase inhibitors (TKIs) remains a therapeutic challenge in the treatment of chronic myeloid leukemia (CML). …”
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Diabetic Foot Care Plan by Gordon Dow, The Diabetic Foot Care Plan Working Group

“…The present care plan was constructed to incorporate the important contributions from these disciplines into practical therapeutic guidelines. The care plan has been divided into three basic sections: assessment, general management and antibiotic therapy. …”
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Combination of Dabrafenib and Trametinib for the Treatment of Relapsed and Refractory Multiple Myeloma Harboring BRAF V600E Mutation by Rūta Čepulytė, Andrius Žučenka, Valdas Pečeliūnas

“…Multiple myeloma (MM) is an incurable plasma cell neoplasia characterized by relapsed and/or refractory (R/R) disease course, which poses a major therapeutic challenge. New therapies, including BRAF V600E mutation targeting, may become a new treatment option for R/R MM. …”
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Nanoparticle Albumin-Bound-Paclitaxel in the Treatment of Metastatic Urethral Adenocarcinoma: The Significance of Molecular Profiling and Targeted Therapy by Yasmin M. Abaza, Carlos Alemany

“…Due to the rarity of this disease, no consensus exists regarding the optimal therapeutic approach. Nanoparticle albumin-bound-paclitaxel has been shown to be effective in the treatment of a number of malignancies including metastatic breast, pancreatic, and bladder cancer. …”
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Granulocytic Sarcoma of Parotid Gland in a 4-Year-Old Child with Subleukemic AML: A Diagnostic Challenge! by Yashwant Ingale, Tushar Patil, Priyanka Chaudhari, Samapika Routray, Manoj Agrawal

“…Excisional biopsy as a therapeutic diagnosis was done. Microscopic examination showed monomorphic population of discohesive, hyperchromatic small round cells having high N : C ratio, coarse chromatin, conspicuous nucleoli, and sometimes angulated nuclei lying in sheets. …”
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Emerging targeted therapies in oral oncology: Focus on EGFR inhibition by Vishnu Priya Veeraraghavan, Shikhar Daniel, Arun Kumar Dasari, Kaladhar Reddy Aileni, Chaitra patil, Santosh R. Patil

“…The EGFR signalling pathway plays a critical role in the development and progression of oral cancer, making it an attractive therapeutic target. Small-molecule tyrosine kinase inhibitors (TKIs) and monoclonal antibodies (mAbs) targeting EGFR have shown promise in preclinical studies and clinical trials. …”
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Complete remission in an advanced hepatocellular carcinoma patient with AXIN1 mutation after systemic therapy: A case report by Yihong Ran, Xiaozhun Huang, Xu Che, Dong Chen

“…This case underscores the importance of incorporating tumor profiling and personalized treatment plans, in addition to adhering to guidelines and standards, for delivering more efficacious and well-tolerated therapeutic options to patients with liver cancer.…”
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Classic and New Diagnostic Approaches to Childhood Tuberculosis by Gladys Guadalupe López Ávalos, Ernesto Prado Montes de Oca

“…However, prevention, diagnostics, and therapeutic efforts have been biased toward adult clinical care. …”
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Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions by Igor Belenichev, Olena Popazova, Nina Bukhtiyarova, Victor Ryzhenko, Sergii Pavlov, Elina Suprun, Valentyn Oksenych, Oleksandr Kamyshnyi

“…This article highlights the critical role of mitochondrial dysfunction in the progression of neurodegenerative diseases and discusses the need for targeted therapeutic strategies to attenuate cellular damage, restore mitochondrial function, and enhance neuroprotection.…”
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Modulation of Immunity by Antiangiogenic Molecules in Cancer by Magali Terme, Orianne Colussi, Elie Marcheteau, Corinne Tanchot, Eric Tartour, Julien Taieb

“…In the last decades a new class of therapeutic drugs have been developed that block tumor angiogenesis. …”
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The role of cell cycle-related genes in the tumorigenesis of adrenal and thyroid neuroendocrine tumors by Ekaterina Filipovich, Ekaterina Gorodkova, Anastasia Shcherbakova, Walaa Asaad, Sergey Popov, Galina Melnichenko, Natalya Mokrysheva, Marina Utkina

“…Our review summarizes differentially expressed cell cycle-related genes with distinct functions, highlighting their potential as therapeutic targets and components of panels used to determine tumor type or aggressiveness. …”
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Not All Neonatal Encephalopathies Are due to Perinatal Hypoxia by Tushar Kulkarni, Lma Dsougi Hussein Mohamed, Mahmoud El Halik, Fatma Abdulla Mohammad Bastaki

“…She required intensive ventilatory and hemodynamic support and was encephalopathic since birth but did not fulfill the criteria for therapeutic hypothermia. Extensive metabolic workup revealed no diagnosis, but neuroimaging showed characteristic findings consistent with the diagnosis of leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation. …”
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Pre-clinical study of curcumin in the treatment of gastric Cancer by Minghui Hao, Chungang Zhang

“…This review aims to summarize the mechanisms through which curcumin affects gastric cancer in both laboratory and animal studies, while also discussing effective strategies for enhancing its therapeutic application.…”
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Antimelanoma and Antityrosinase from Alpinia galangal Constituents by Chih-Yu Lo, Po-Len Liu, Li-Ching Lin, Yen-Ting Chen, You-Cheng Hseu, Zhi-Hong Wen, Hui-Min Wang

“…Our results revealed the anticancer effects of A. galangal compounds, and therefore, the target compounds could be potentially applied in the therapeutic application and the food industry.…”
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Successful Treatment of Candida parapsilosis Fungemia in Two Preterms with Voriconazole by Emel Altuncu, Hulya Bilgen, Ahmet Soysal, Eren Ozek

“…Both of the patients’ blood cultures were persistently positive for C. parapsilosis despite high therapeutic doses (AMB: 7 mg/kg per day). After starting voriconazole blood cultures became negative and both of the patients were treated successfully without any side effects. …”
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Hyperbilirubinemia: Does It Matter? by Lajos Okolicsanyi, Giulia Martina Cavestro, Claudia Guatti-Zuliani

“…The knowledge of these conditions is increasingly important because orthotopic liver transplantation may be a therapeutic choice for some severe forms. Furthermore, early diagnosis is necessary to avoid unnecessary medical investigations for the otherwise relatively common, benign unconjugated hyperbilirubinemia. …”
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Addressing the limitations of the regulatory landscape in South Africa regarding advanced cell and gene therapies and related sectors involving human cells, tissues and organs by I M Viljoen, M S Pepper

“…These products are complex, diverse and therapeutically specific, requiring specialised regulatory frameworks. …”
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The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review by Arman Hamzei, Sara Hallaji, Seyed Farzin Hosseini, Arman Keymoradzadeh

“…This review article delves into the mechanisms underlying KD's potential therapeutic effects on glioma and its efficacy, safety profile, and overall role in glioma treatment.…”
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