The significance of radiological methods in the diagnostics of Gastroenterological diseases (according to the materials of the 18th Russian Gastroenterology Week) by Z. A. Lemeshko

“…In the recent years the radiological methods are used not only in the detection of the different morbid conditions but in the differential diagnostics of the digestive diseases both in the therapeutic practice as well as during the small invasive interventions. …”
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A Rare Case of Septic Shock Secondary to Emphysematous Hepatitis by Khaled M. Nada, Ibrahim El Husseini, Mohammad E. Abu Hishmeh, Neerav S. Shah, Nadezhda Ibragimova, Riyad Basir

“…Emphysematous hepatitis is a rapidly progressive infection that can be fatal in the absence of appropriate therapeutic intervention. Initial clinical manifestations are usually subtle and thus high clinical suspicion is required for early diagnosis and management of this condition to help decrease the mortality rates.…”
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Use of the Tei Index in the Conservative Management of TRAP Sequence Pregnancies Diagnosed during the Periviable Period: A Case Series by Kristina Martimucci, Theresa Kuhn, Robyn Bilinski, Jesus Alvarez-Perez

“…There are minimal sonographic tools for the guidance of a fetal therapeutic interventional procedure during the second trimester or timing of delivery during the third trimester to reduce morbidity and mortality of a viable fetus. …”
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Harnessing amino acid pathways to influence myeloid cell function in tumor immunity by Jiongli Pan, Yi Lin, Xinyuan Liu, Xiaozhen Zhang, Tingbo Liang, Xueli Bai

“…Furthermore, we explore the therapeutic potential of targeting amino acid metabolism to enhance anti-tumor immunity, offering insights into novel strategies for cancer treatment.…”
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The Role of Human Gut Microbe Ruminococcus gnavus in Inflammatory Diseases by Sasmitra Kandasamy, Vengadesh Letchumanan, Kar Wai Hong, Kah-Ooi Chua, Nurul Syakima Ab Mutalib, Alvin Lai Oon Ng, Long Chiau Ming, Hui Xuan Lim, Sivakumar Thurairajasingam, Jodi Woan-Fei Law, Loh Teng-Hern Tan

“…The increasing evidence of elevated R. gnavus abundance in various inflammatory conditions suggests its potential as a therapeutic target. Despite this, there are limited studies on treatment strategies targeting R. gnavus. …”
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Endothelial-Mesenchymal Transition in Regenerative Medicine by Damian Medici

“…This review discusses the signaling mechanisms and therapeutic inhibitors of EndMT, as well as the role of EndMT in development, disease, acquiring stem cell properties and generating connective tissues, and its potential as a novel mechanism for tissue regeneration.…”
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Improving CD3 bispecific antibody therapy in solid tumors using combination strategies by Katy Lloyd, Jim Middelburg, Vitalijs Ovcinnikovs, Nora Pencheva, Kristel Kemper, Thorbald van Hall

“…Furthermore, tumor surface antigen selection for an optimal therapeutic window and acceptable collateral damage to normal tissues is challenging. …”
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Inflammation in Retinal Vein Occlusion by Avnish Deobhakta, Louis K. Chang

“…This improved understanding of the role of inflammation in retinal vein occlusion has allowed the development of new treatments for the disorder, with additional therapeutic targets and strategies to be identified as our understanding of the topic increases.…”
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Nucleic Acid-Based Therapy Approaches for Huntington's Disease by Tatyana Vagner, Deborah Young, Alexandre Mouravlev

“…The aim of this paper is to outline the nucleic acid-based therapeutic strategies that have been tested to date.…”
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Isolated Interrupted Aortic Arch: Unexpected Diagnosis in a 63-Year-Old Male by Hassan Javadzadegan, Jahan Porhomayon, Alireza Sadighi, Mehrdad Yavarikia, Nader Nader

“…The aim of this paper, is to review the diagnostic and therapeutic options for treatment of the interrupted aortic arch.…”
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Goal Attainment Scale and Clinical Efficacy Evaluation of Acupuncture by Dong LIN, Wanyu ZHUANG, Xiaozhen HUANG, Lili LIN, Qiang WU

“…Objective:To analyze the application prospect of goal attainment scale (GAS) in clinical efficacy evaluation of acupuncture, and then explore the establishment of individualized clinical assessment system of acupuncture.Methods:This article introduced a mature and individualized clinical evaluation method GAS, described its application in therapeutic efficacy assessment of acupuncture therapy in patients with mental retardation, and then analyzed the advantages and limitations of GAS.Results:Since GAS was an individualized clinical efficacy evaluation system, it could provide a good idea for the evaluation of the clinical efficacy of acupuncture.Conclusion:Through inducing GAS into clinical evaluation of acupuncture, it is possible to establish a clinical efficacy evaluation system suitable for acupuncture after repeated clinical practice and continuously improvement.…”
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A Molecular and Clinical Review of Stem Cell Therapy in Critical Limb Ischemia by Punam P. Parikh, Zhao-Jun Liu, Omaida C. Velazquez

“…The primary benefit of SCT is to induce therapeutic neovascularization and promote collateral vessel formation to increase blood flow in the ischemic limb and soft tissue. …”
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Adipokines and Hepatic Insulin Resistance by Yu Li, Lin Ding, Waseem Hassan, Daoud Abdelkader, Jing Shang

“…Since hepatic insulin resistance plays the key role in the whole body insulin resistance, clarification of the regulatory processes about hepatic insulin resistance by adipokines in rodents and human would seem essential in order to understand the mechanism of type 2 diabetes and for developing novel therapeutic strategies to treat it.…”
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Complex management of GS (Good's syndrome) with persistent COVID-19 infection and polymicrobial infections: A case report by Yijiao Xu, Lumin Wang, Zhisheng Chen, Ying Huang, Jiaxin Liu, Huijun Zhang, Hongni Jiang

“…This case report highlights the diagnostic and therapeutic complexities faced by a 56-year-old female with Good's syndrome (GS), who presented with persistent Coronavirus Disease 2019 (COVID-19) infection alongside Aspergillus spp, cytomegalovirus, and Pseudomonas aeruginosa co-infection, which collectively contributed to severe pulmonary involvement. …”
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Consensus of Chinese Experts on the Diagnosis and Treatment of Type Ⅰ Interferonopathy by Chinese Alliance of Pediatric Rheumatic & Immunologic Diseases, Chinese Pharmacists Association Rare Diseases Medication Working Committee

“…Therefore, the Chinese Alliance of Pediatric Rheumatic & Immunologic Diseases and Chinese Pharmacists Association Rare Diseases Medication Working Committee has developed this consensus document to offer detailed recommendations pertaining to the definition, genetic categorization, clinical presentations, diagnostic approaches, and therapeutic management of type Ⅰ interferonopathy.…”
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Sequential Release HydroLipo System for STING Gene Epigenetic Reprogramming and Immune Activation in Glioblastoma by Hao Yu, Wenjing Liu, Kaikai Ding, Jiangjie Wu, Cheng Wang, Siyuan Wang, Lingyun Wu, Qiuying Tang, Xin Yin, Kan Jiang, Danfang Yan, Xu Wang, Si Chen, Senxiang Yan

“…These findings underscore the potential of the SRHLS as a promising therapeutic strategy for GBM.…”
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Gut microbiota and Parkinson’s disease by Lin Wang, Ying Cui, Bingyu Han, Yitong Du, Kenish Sirajbhai Salewala, Shiya Wang, Wenlu Zhao, Hongxin Zhang, Sichen Wang, Xinran Xu, Jianpeng Ma, Yan Zhu, Houzhen Tuo, Ting Gao

“…The microbiota–gut–brain axis plays a crucial role in the development and progression of PD, and numerous studies have demonstrated the potential therapeutic benefits of modulations in the intestinal microbiota. …”
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An Update on Inflamm-Aging: Mechanisms, Prevention, and Treatment by Shijin Xia, Xinyan Zhang, Songbai Zheng, Ramin Khanabdali, Bill Kalionis, Junzhen Wu, Wenbin Wan, Xiantao Tai

“…Here, we review studies of inflamm-aging that explore the concept, pathological features, mechanisms, intervention, and the therapeutic strategies of inflamm-aging in disease progression.…”
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Efficacy and Safety Concerns with Sn-Mesoporphyrin as an Adjunct Therapy in Neonatal Hyperbilirubinemia: A Literature Review by Prakar Poudel, Sudhir Adhikari

“…After successful results in in-vitro and animal studies, tin mesoporphyrin is now under phase II clinical trial to test for preventive and therapeutic efficacy in unconjugated hyperbilirubinemia. …”
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Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases by Maria H. Madeira, Raquel Boia, Paulo F. Santos, António F. Ambrósio, Ana R. Santiago

“…A better understanding of the events elicited and mediated by retinal microglia will contribute to the clarification of disease etiology and might open new avenues for potential therapeutic interventions. This review aims at giving an overview of the roles of microglia-mediated neuroinflammation in major retinal degenerative diseases like glaucoma, age-related macular degeneration, and diabetic retinopathy.…”
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