RNA Editing and Drug Discovery for Cancer Therapy by Wei-Hsuan Huang, Chao-Neng Tseng, Jen-Yang Tang, Cheng-Hong Yang, Shih-Shin Liang, Hsueh-Wei Chang

“…Therefore, RNA editing may be a potential target for therapeutic natural products. In this review, we provide a literature overview of the biological functions of RNA editing on gene expression, diseases, cancers, and drugs. …”
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Specific Blood Cells Derived from Pluripotent Stem Cells: An Emerging Field with Great Potential in Clinical Cell Therapy by Qian Luo, Honghu Li, Wei Shan, Cong Wei, Yan Long, Shuyang Cai, Xiangjun Zeng, Xue Li, Yulin Xu, Xiaoxiao Xu, Yi Luo, Pengxu Qian, He Huang

“…This short review outlines the technologies used for hematopoietic differentiation in recent years. In addition, the therapeutic value of PSCs as a potential source of various blood cells is also discussed as well as its challenges and directions in future clinical applications.…”
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4D printing: innovative solutions and technological advances in orthopedic repair and reconstruction, personalized treatment and drug delivery by Chenxi Shen, Aiyong Shen

“…This review focuses on the advances of 4D printing technology in orthopedics, including its applications in bone repair and reconstruction, personalized treatment, and drug delivery. 4D printing enables the creation of bionic scaffolds and fixation devices for bone repair, customized implants matching patients' conditions for personalized treatment, and specific carriers for accurate drug release and delivery, which together contribute to accelerating bone healing, providing exclusive treatments, enhancing therapeutic effects and reducing side effects, thus helping improve orthopedic medicine. …”
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TRPM7 and TRPM8 Ion Channels in Pancreatic Adenocarcinoma: Potential Roles as Cancer Biomarkers and Targets by Nelson S. Yee, Ada S. Chan, Julian D. Yee, Rosemary K. Yee

“…We are currently investigating the mechanisms which mediate the functional roles of TRPM7 and TRPM8 and attempting to develop these ion channels as clinical biomarkers and therapeutic targets for achieving the goal of personalized therapy in pancreatic cancer.…”
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Rare complication of skin necrosis after endoscopic debridement and cutaneo-fascial suture for a massive Morel-Lavallée lesion in Korea: a case report by Youngmin Kim, Jayun Cho, Myung Jin Jang, Kang Kook Choi

“…Due to its resistance to conservative treatments such as drainage or compression dressing, various therapeutic methods have been developed for MLL. However, no standardized guidelines currently exist. …”
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Clinical Practice Guideline for the Treatment of Percarditis by René Mick Cabrera Núñez, Lázaro de la Cruz Avilés

“…They are established to help doctors select the best possible treatment strategy for a specific patient, who suffers from a certain disease, not only taking into account the final result, but also weighing the risks and benefits of a diagnosis or concrete therapeutic procedure. This is a clinical practice guide for the treatment of acute pericarditis, defined as a syndrome caused by inflammation of the pericardium due to various etiologies. …”
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Compartment Syndrome following Open Femoral Fracture with an Isolated Femoral Vein Injury Treated with Acute Repair by David Walmsley, Terry Axelrod, Sebastian Rodriguez-Elizalde

“…She was subsequently found to have a DVT in her femoral vein at the level of the repair and was started on therapeutic anticoagulation. This case highlights the importance of recognition of isolated venous injuries in a trauma setting as a risk factor for developing compartment syndrome.…”
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Avelumab-Induced Scleroderma in a Patient with Metastatic Squamous Cell Carcinoma of the Lung by Jeffrey L. Dobrzynski, Blake E. Vest, Brian L. Swick

“…A proposed mechanism is discussed along with the clinical presentation of symptoms and associated therapeutic response in cancer treatment. This case contributes to the few existing reports of immune checkpoint inhibitor-induced scleroderma to better understand the implications in the management of cutaneous immune-related adverse events.…”
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Plasmacytoid Dendritic Cells: From Heart to Vessels by Rosalinda Sorrentino, Silvana Morello, Aldo Pinto

“…It is thus clear that a better identification of pDCs activity in cardiovascular diseases can not only elucidate pathological mechanisms but also lead to new therapeutic approaches.…”
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Essential oils – a review of the natural evolution of applications and some future perspectives by Stanislava Ivanova, Yana Gvozdeva, Radiana Staynova, Daniela Grekova-Kafalova, Vanya Nalbantova, Niko Benbassat, Nina Koleva, Kalin Ivanov

“…Although there are many studies that involve EOs, the therapeutic potential of EOs is not fully investigated. …”
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Role of Microglia in CNS Autoimmunity by Tobias Goldmann, Marco Prinz

“…Hence, understanding microglia involvement in MS offers new exciting paths for therapeutic intervention.…”
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Single-Cell Transcriptome Analysis of Human Adipose-Derived Stromal Cells Identifies a Contractile Cell Subpopulation by Elize Wolmarans, Juanita Mellet, Chrisna Durandt, Fourie Joubert, Michael S. Pepper

“…The potential for human adipose-derived stromal cells (hASCs) to be used as a therapeutic product is being assessed in multiple clinical trials. …”
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Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment by Liu Hanqing, Tu Zhigang, Feng Fan, Shi Haifeng, Chen Keping, Xu Ximing

“…A number of virosome- -based prophylactic and therapeutic products with high safety profiles are currently available in the market. …”
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Identification of sepsis-associated encephalopathy biomarkers through machine learning and bioinformatics approaches by Jingchao Lei, Jia Zhai, Jing Qi, Chuanzheng Sun

“…These findings provide insights into SAE pathogenesis and suggest potential therapeutic targets.…”
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miR-22-3p/PGC1β Suppresses Breast Cancer Cell Tumorigenesis via PPARγ by Xuehui Wang, Zhilu Yao, Lin Fang

“…In conclusion, miR-22-3p/PGC1β suppresses BC cell tumorigenesis via PPARγ, which may become a potential biomarker and therapeutic target.…”
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Mathematical modeling of glioma therapy using oncolytic viruses by Baba Issa Camara, Houda Mokrani, Evans K. Afenya

“…In attempts to prolong the lengths of survivaltimes for patients with malignant brain tumors, novel therapeutic alternatives such as gene therapy withoncolytic viruses are currently being explored. …”
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Diarrhoea in Patients with COVID-19 by A. A. Sheptulin

“…The causes of diarrhoea may relate to the virus direct interaction with the angiotensin-converting enzyme 2 (ACE2) receptors in mucosa, its impact on the intestinal microbiota and therapeutic side effects. The possible occurrence of diarrhoea as a leading clinical manifestation of the coronavirus infection hampers its timely diagnosis. …”
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Coronary Microvascular Function and Beyond: The Crosstalk between Hormones, Cytokines, and Neurotransmitters by Carlo Dal Lin, Francesco Tona, Elena Osto

“…Thus, expanding our knowledge on how these factors influence the cardiovascular system can lead to novel therapeutic strategies to improve patient care. In the present paper, we review novel concepts on the role of endocrine, immune, and nervous factors in the modulation of microvascular coronary function.…”
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Art-making as a gateway to the inner self: A phenomenological exploration of intuitive collage in coaching by Elizabeth Ahmann, Micah Saviet, Marybeth Missenda

“…Art has long been used as a common creative outlet and a therapeutic modality. Recently, coaches have begun to explore art-making in the coaching engagement. …”
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How to Design a Study and Write a Grant in Radiology? by Pankaj Gupta, Manphool Singhal

“…Parallelly, interventional radiology has benefited and interventional radiologists are at the forefront of several therapeutic procedures. One of the key factors in the growth of radiology is high-quality research. …”
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