The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis by Emer P. Reeves, David A. Bergin, Michelle A. Murray, Noel G. McElvaney

“…This present review discusses the biological role of GAGs in the lung, as well as their involvement in CF respiratory disease, and their potential as therapeutic targets.…”
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Effects of PCSK9 inhibitors on metabolic-associated fatty liver disease: a short review by Ewelina Jakielska, Paweł Głuszak, Marta Walczak, Wiesław Bryl

“…The increasing number of cases creates the need for new therapeutic methods aimed at improving patient outcomes. …”
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Stenotrophomonas maltophilia – A Threatening Nosocomial Pathogen by Ruchita Gawande, Suvarna Sande

“…S. maltophilia shows high intrinsic and acquired resistance to all commonly used antibiotics, limiting the number of therapeutic choices. The aim of this review is to summarize the virulence factors, antibiotic resistance mechanisms, diagnosis, and treatment of S. maltophilia infections.…”
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Persistent Peril: Confronting Recurrent Chest Abscess from Nontuberculous Mycobacteria by P Prem Ananth, R Anand, S Raghul Raj, N Nagarajan, M Thoupikka

“…Recurrent chest wall abscesses, particularly those caused by nontuberculous mycobacteria (NTM) such as Mycobacterium fortuitum, are uncommon and pose significant diagnostic and therapeutic challenges. Our case report details a 42-year-old male with recurrent chest wall abscess, where the underlying etiology was traced to a near-drowning incident at the age of 18. …”
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Uterine Cervix Cancer. Different Progress among Prevention, Early Diagnosis and Treatment by Víctor Manuel Medina Pérez, Rodolfo Arián Morales Yera, Liudmila Sierra Pérez

“…This disease has been associate to multiple risk factors, but with the improvement in the papilloma virus detection it was demonstrated that 98 % of the cases detected is due to this virus. New therapeutic strategies focus on molecular targets, inmunotherapy and the combination of these and old treatments as chemio-radio-therapy. …”
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Implant considerations for patients with periodontitis by YANG Ze, PAN Yaping

“…It systematically describes how implant treatment should be considered and maintained in the therapeutic process, which provides reference for clinical treatment.…”
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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…First, we treated all drugs with a similar pharmacology as the same, rather than assigning their therapeutic value based on year of introduction. Second, our approach recognizes that innovations emerge in waves and that drugs within a particular group are more similar therapeutically to each other than to other existing drugs, or other drugs introduced in the same or different years. …”
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Melittin ameliorates schistosomiasis-induced liver fibrosis by suppressing signal transducer and activator of transcription 3 and nuclear factor kappa B by Ola I. Rozik, Manal M. Hussein, Ahmed S. El-elebiarie, Soad Nady

“…The therapeutic effect of MEL in a BALB/c mouse model of Schistosoma mansoni-induced liver fibrosis was studied in this research. …”
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The use of N-acetylcysteine to prevent further progression of preeclampsia by I Wayan Agung Indrawan, Leny Farida

“…These highlight the potential of NAC as a therapeutic intervention for preeclampsia, particularly in women at high risk. …”
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Cimetidine Pharmacodynamics and Pharmacokinetics in Healthy Subjects: A Comparison of Tablets and Suspension by ABR Thomson, P Kirdeikis, L Zuk, RE Samuels, P Zarevics

“…Comparing cimetidine concentration (Cmax) and lower percentage time plasma cimetidine concentration was at least 0.5 μg/mL (the minimum therapeutic level). These pharmacokinetic variations between cimetidine suspension and tablets may have partially explained the pharmacodynamic differences of the lower area under the pH time curve (0 to 6 h). …”
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Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments by Liu C, Liu W, Lu H, Fan Y, Wang A

“…TNF, VEGFA, MMP9, PTGS2, and TLR4 might be the hub therapeutic target genes. The TLR4/NF-κB signaling pathway might be the foremost pathway in baicalin against gout. …”
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Emerging Strategies in Cartilage Repair and Joint Preservation by Mircea Adrian Focsa, Sorin Florescu, Armand Gogulescu

“…In response, regenerative medicine has developed advanced therapeutic strategies, including cell-based therapies, gene editing, and bioengineered scaffolds, to promote cartilage regeneration and restore joint function. …”
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Screening of Insertion Sites and Tags on EV-A71 VP1 Protein for Recombinant Virus Construction by Miaomiao Kang, Xiangyi Li, Xiaohong Li, Rui Yu, Shuo Zhang, Jingjing Yan, Xiaoyan Zhang, Jianqing Xu, Buyong Ma, Shuye Zhang

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Initial Assessment of β-Adrenoceptor-Activated Brown Adipose Tissue in Streptozotocin-Induced Type 1 Diabetes Rodent Model Using [F]Fluorodeoxyglucose Positron Emission Tomography/... by Aparna Baranwal, M. Reza Mirbolooki, Jogeshwar Mukherjee

“…Drugs that enhance BAT activity may have a potential for therapeutic development in lowering blood sugar in insulin-resistant diabetes. …”
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Enhanced detection of mild cognitive impairment in Alzheimer’s disease: a hybrid model integrating dual biomarkers and advanced machine learning by John Sahaya Rani Alex, R. Roshini, G. Maneesha, Jeetashree Aparajeeta, B. Priyadarshini, Chih-Yang Lin, Chi-Wen Lung

“…This approach enhances diagnostic accuracy and provides a more comprehensive assessment, allowing for earlier and more targeted therapeutic interventions.…”
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STAT3 Expression and Its Correlation with PD-L1 Expression in Non-Hodgkin’s Lymphoma and Hodgkin’s Lymphoma at Dr. Saiful Anwar Regional Public Hospital in Malang, Indonesian Popul... by Ailen Oktaviana Hambalie, Eviana Norahmawati, Agustina Tri Endharti, Diah Prabawati Retnani, Nayla Rahmadiani

“…Despite the availability of many therapeutic modalities for lymphoma, such as Brentuximab vedotin, Nivolumab, and Pembrolizumab, it is still necessary to identify appropriate strategies with minimal side effects. …”
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Third Trimester Lower Extremity Lymphorrhea by Kaori Morimoto, Luke O’Rourke

“…There is also a lack of evidence and recommendations regarding the therapeutic benefit and safety profile of diuretic use to treat profound pregnancy-associated edema. …”
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HMOX1 as a potential drug target for upper and lower airway diseases: insights from multi-omics analysis by Enhao Wang, Shazhou Li, Yang Li, Tao Zhou

“…Molecular docking was used to identify potential therapeutic agents. Results HMOX1 expression was significantly elevated in CRSwNP. …”
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Examining antibiotic use in Kenya: farmers’ knowledge and practices in addressing antibiotic resistance by Harrison Rware, Kansiime K. Monica, Mugambi Idah, Makale Fernadis, Ikiror Davis, Wako Buke, Danielsen Solveig, Karanja Daniel, Chacha Duncan, Byskov Morten, Hyams Keith

“…Antibiotics are used for both therapeutic and non-therapeutic purposes, the latter mainly in form of growth promoters and feed enhancers in poultry. …”
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Cosmetic Appeal, HRQoL, and Effectiveness of Simple and Pseudotesticular Techniques of Orchidectomy in Prostate Cancer by Ijeoma N. C. Chibuzo, Augustine O. Takure, Olayiwola B. Shittu, Linus I. Okeke

“…This study compared the HRQoL, therapeutic efficacy, and cosmetic appeal of BSO with endogenous pseudotesticular techniques of bilateral subcapsular orchidectomy (BSCO) and bilateral-epididymal-sparing orchidectomy (BESO). …”
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