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481
Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies
Published 2012-01-01“…These results suggest an important role of extracellular NM23-H1 in the malignant progression of leukemia and a potential therapeutic target for these malignancies.…”
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482
The crosstalk between senescence, tumor, and immunity: molecular mechanism and therapeutic opportunities
Published 2025-01-01“…Understanding how senescence regulates antitumor immunity, along with new therapeutic interventions, is essential for managing tumor cell senescence and remodeling the immune microenvironment.…”
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483
Arterial Hypertension and Interleukins: Potential Therapeutic Target or Future Diagnostic Marker?
Published 2019-01-01“…Further research is needed to evaluate whether drugs targeting hypertensive-linked proinflammatory cytokines, such as monoclonal antibodies, could become a new therapeutic option in treating arterial hypertension.…”
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484
Research progress on the therapeutic roles and mechanisms of hydrogen-rich water in periodontitis
Published 2025-01-01“…Therefore, further clinical studies are required to validate the therapeutic significance and optimal therapeutic regimen of HRW in human periodontitis. …”
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485
Editorial: New insights into intracellular pathways and therapeutic targets in CNS diseases
Published 2025-02-01Get full text
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486
Therapeutic and subsidiarity principles: an approach to the humanizing character of the Bioethics Ecuadorian Society
Published 2019-11-01“…The principle of totality or therapeutic, and that of sociability and subsidiarity, are the object of reflection in this study, as well as the way in which they are manifested through the Ecuadorian Society of Bioethics, through the analytical and conceptual foundation on the origin and consistency of these. …”
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487
A review of gut microbiota as a therapeutic approach for Parkinson’s disease
Published 2024-12-01“…This review focuses on the connection between gut dysbiosis, PD pathology, and current microbial-based therapeutic interventions. Furthermore, research into innovative approaches to modulate the GM and reinforce gut epithelial integrity is crucial to halting or slowing PD progression.…”
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488
Failure of Colorectal Anastomosis: Risk Factors, Prevention, Diagnosis, Therapeutic Tactics
Published 2019-05-01Get full text
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489
Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes
Published 2024-12-01“…Thus, the treatment of the disease urgently requires the discovery of novel therapeutic approaches. This review identifies and discusses key molecular and genetic targets for LC therapy, highlighting recent advancements and potential clinical applications. …”
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490
Unveiling the therapeutic potential of insect-derived natural products for drug discovery
Published 2025-01-01Get full text
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491
Validation of Colchicine Assay Method for Therapeutic Drug Monitoring in Human Plasma
Published 2022-12-01Subjects: Get full text
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492
Role of intestinal probiotics in the modulation of lipid metabolism: implications for therapeutic treatments
Published 2023-09-01“…Moreover, we discuss the underlying mechanisms of intestinal probiotics regulating lipid metabolism and summarize the therapeutic strategies for abnormal lipids metabolism. …”
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493
Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge
Published 2016-01-01“…We describe the added value of therapeutic drug monitoring by presenting the case of a preterm infant with severe NEC treated with meropenem. …”
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494
Uterus Conservative Surgery. A Therapeutic Alternative in Postpartum Obstetric Hemorrhage
Published 2016-10-01Get full text
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495
Drug Repositioning for Gynecologic Tumors: A New Therapeutic Strategy for Cancer
Published 2015-01-01“…The goals of drug repositioning are to find a new pharmacological effect of a drug for which human safety and pharmacokinetics are established and to expand the therapeutic range of the drug to another disease. Such drug discovery can be performed at low cost and in the short term based on the results of previous clinical trials. …”
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496
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497
Lipin-1: Is a promising therapeutic candidate for head and neck cancer
Published 2024-06-01Get full text
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498
Therapeutic Effectiveness of Plant Medicine in Treating Xerostomia-A Systematic Review
Published 2024-12-01“…This systematic review aims at assessing therapeutic effectiveness of plant medicine in treatment of patients with xerostomia. …”
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499
Plasma brain-related biomarkers and potential therapeutic targets in pediatric ECMO
Published 2025-01-01“…Further research continues to elucidate the role of biomarkers as predictors, prognosticators, and therapeutic targets.…”
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500
Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease
Published 2025-01-01Get full text
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