Gallbladder perforation in a patient undergoing PCNL: Case report and literature review by Alessandro Vengjer, André Segura da Motta, Matheus Campos Alves Corrêa, Julia Corazza Nitta Yoshisaki, Marcelo Ribeiro de Azevedo, Olavo Napoleão de Araújo Neto

“…Percutaneous nephrolithotripsy (PCNL) is an effective therapeutic approach in cases of lithiasis, which is prone to complications. …”
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Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives by Filippo Luca Gurgoglione, Giorgio Benatti, Andrea Denegri, Davide Donelli, Marco Covani, Mattia De Gregorio, Gabriella Dallaglio, Rebecca Navacchi, Giampaolo Niccoli

“…Finally, we will provide an overview of novel emerging therapeutic strategies for CMD.…”
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Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases by Dulshara Sachini Amarasekara, Jiyeon Yu, Jaerang Rho

“…Here, we review and discuss the involvement of the inflammatory cytokine network in the pathophysiological aspects and the therapeutic advances in inflammatory autoimmune diseases.…”
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Maintenance Electroconvulsive Therapy in a Patient with Treatment-Resistant Paranoid Schizophrenia and Comorbid Epilepsy by Beppe Micallef-Trigona, Joseph Spiteri

“…We describe a patient with a serious case of paranoid schizophrenia and comorbid epilepsy who had not responded to typical and atypical antipsychotic medication, but responded remarkably to acute ECT and required maintenance ECT to sustain a positive therapeutic response.…”
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Explorer les parcours thérapeutiques des enfants atteints de cancer au Burkina Faso by Marie-Thérèse Arcens Somé, Aude Nikiema

“…Interviews were conducted in the capital, Ouagadougou, with children suffering from cancer, their families and healthcare staff. The therapeutic pathways collected were mapped, and their analysis highlights their complexity and duration. …”
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Nano Delivery System for Atherosclerosis by Zhuoyi Rong, Xuan He, Tianjian Fan, Haitao Zhang

“…Currently, drug therapy, the primary therapeutic strategy for atherosclerosis, faces challenges such as poor stability and significant side effects. …”
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Sedation and Analgesia in Children with Developmental Disabilities and Neurologic Disorders by Todd J. Kilbaugh, Stuart H. Friess, Ramesh Raghupathi, Jimmy W. Huh

“…Sedation and analgesia performed by the pediatrician and pediatric subspecialists are becoming increasingly common for diagnostic and therapeutic purposes in children with developmental disabilities and neurologic disorders (autism, epilepsy, stroke, obstructive hydrocephalus, traumatic brain injury, intracranial hemorrhage, and hypoxic-ischemic encephalopathy). …”
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Successful Conservative Treatment of a Cesarean Scar Pregnancy with Systemically Administered Methotrexate and Subsequent Dilatation and Curettage: A Case Report by Anis Fadhlaoui, Mohamed Khrouf, Khaled Khémiri, Kais Nouira, Anis Chaker, Fethi Zhioua

“…Cesarean scar pregnancy is a rare type of ectopic pregnancy associated with severe complications such as uterine rupture, uncontrollable bleeding which may lead to hysterectomy, and definitive infertility. Many therapeutic options are available such as Dilatation & Curetage, excision of trophoblastic tissues using either laparotomy or laparoscopy, systemically administered Methotrexate, and more recently uterine artery embolization. …”
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Scalp Necrosis Revealing Severe Giant-Cell Arteritis by Safa Idoudi, Marouene Ben Kahla, Fares Mselmi, Badreddine Sriha, A. Guiga, Samia Ayachi, Colandane Belajouza, Mohamed Denguezli

“…Scalp necrosis associated with GCA is a rare occurrence with approximately 100 cases reported in the literature to date. It is a therapeutic emergency requiring urgent management as it may lead to irreversible loss of vision. …”
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Therapy process in migration circumstances (Round-Table Discussion) by Anna Varga, Marina Travkova, Irina Znamenskaya

“…The participants of the roundtable discussion, which took place on November 8, 2024, talked about changes in the client-therapeutic interaction and the therapy itself in the current conditions, and tried to find answers to important questions.…”
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2024 Polish recommendations for the management of familial hypercholesterolemia in children and adolescents by Małgorzata Myśliwiec, Marta Bandura, Anna Wołoszyn-Durkiewicz, Matylda Hennig, Mieczysław Walczak, Jarosław Peregut-Pogorzelski, Jolanta Sykut-Cegielska, Maria Miszczak-Knecht, Krzysztof Chlebus, Bartosz Wasąg, Agnieszka Zmysłowska, Maciej Banach

“…Despite increasing medical knowledge, diagnostic testing, and a growing number of therapeutic options, the effectiveness of detecting and treating FH remains highly insufficient. …”
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The Current Knowledge of the Role of PPAR in Hepatic Ischemia-Reperfusion Injury by M. Elias-Miró, M. B. Jiménez-Castro, M. Mendes-Braz, A. Casillas-Ramírez, C. Peralta

“…The data suggest that further investigations are required to elucidate whether PPAR could be a potential therapeutic target in liver surgery and to determine the most effective therapies that selectively regulate PPAR with minor side effects.…”
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Genetics of Uveal Melanoma and Cutaneous Melanoma: Two of a Kind? by Thomas van den Bosch, Emine Kilic, Dion Paridaens, Annelies de Klein

“…Cutaneous melanoma and uveal melanoma both derive from melanocytes but show remarkable differences in tumorigenesis, mode of metastatic spread, genetic alterations, and therapeutic response. In this review we discuss the differences and similarities along with the genetic research techniques available and the contribution to our current understanding of melanoma. …”
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A Role for Notch Signalling in Breast Cancer and Endocrine Resistance by Ahmet Acar, Bruno M. Simões, Robert B. Clarke, Keith Brennan

“…As a result, inhibiting Notch signalling with therapeutic agents is being explored as a promising treatment option for breast cancer patients.…”
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Comprehensive genomic profiling of primary bladder mucinous adenocarcinoma, a rare genitourinary cancer: A case report by Shinkuro Yamamoto, Shingo Ashida, Tomoya Nao, Kaho Murakami, Ryohei Iga, Tsutomu Shimamoto, Hideo Fukuhara, Nobutaka Shimizu, Satoshi Fukata, Atsushi Kurabayashi, Takashi Karashima, Keiji Inoue

“…These genomic profiling test results may lead to the development of novel therapeutic agents for primary bladder mucinous adenocarcinoma.…”
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Extrapontine Myelinolysis following Extreme Hypernatremia and Hyperosmolarity by Jan-Niclas Schwade, Lior Haftel, Lars Rühe, Matthias Endmann

“…Cranial magnetic resonance imaging (cMRI) was performed and (mis)interpreted for meningoencephalitis, with corresponding diagnostic and therapeutic implications. The patient had extrapontine myelinolysis. …”
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Optical Coherence Tomography in Huntington's Disease—A Potential Future Biomarker for Neurodegeneration? by Clancy Cerejo, Nicolas De Cleene, Elias Mandler, Katarina Schwarzová, Samuel Labrecque, Philipp Mahlknecht, Florian Krismer, Atbin Djamshidian, Klaus Seppi, Beatrice Heim

“…Lately, there have been multiple ongoing clinical trials targeting therapeutic agents for preventing disease onset or slowing disease progression in HD. …”
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Thirty Years Later: Evolution of Treatment for Acute Left Main Coronary Artery Occlusion by Moshe Y. Flugelman, Nissan Ben-Dov, Basheer Karkabi, Ronen Jaffe

“…These patients exemplify the progress in therapeutic cardiology over the last 30 years.…”
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Management of Stable Angina with Ivabradine as Safe Alternative to Patients with Myasthenia Gravis by Giuliano Ohde Dalledone, Gustavo Lenci Marques, Renata Dal-Prá Ducci, Arnaldo Laffitte Stier Junior, Cláudia Suemi Kamoi Kay, Lineu Cesar Werneck, Paulo José Lorenzoni, Rosana Herminia Scola

“…The patient presented an improvement of neurological and cardiac symptoms, bringing ivabradine as one more therapeutic option to similar patients. In this report we recommend ivabradine as an effective and safe drug for treatment of stable angina in MG patients.…”
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Erythrocytes and Erythropoietin by Michael Föller, Lars Kaestner, Elisabetta Straface, Johannes Vogel

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