Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases by Punita Kalia, Rohini Ravindran Nair, Suresh Singh Yadav

“…This study highlights the potential use of exportins as novel prognostic biomarkers and therapeutic targets for colon adenocarcinoma progression and management.…”
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A critical period for paired-housing-dependent autistic-like behaviors attenuation in a prenatal valproic acid-induced male mouse model of autism by Jian-Quan Yang, Bao-Qi Yin, Chao-Hua Yang, Miao-Miao Jiang, Zhe Li

“…So our study demonstrates the therapeutic potential of environmental intervention during a critical period in the treatment of ASD.…”
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Hyperactivity and Pro-inflammatory Functions of Platelets in Diabetes by Jordan Greaves, Giordano Pula

“…The understanding of the mechanisms underlying the contribution of platelets to cardiovascular pathologies in DM will help the development of targeted therapeutic strategies able to reduce cardiovascular risk in these patients. …”
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C-Methionine Positron Emission Tomographic Imaging of Biologic Activity of a Recurrent Glioblastoma Treated with Stereotaxy-Guided Laser-Induced Interstitial Thermotherapy by Norbert Galldiks, Wernholt von Tempelhoff, Deniz Kahraman, Lutz W. Kracht, Stefan Vollmar, Gereon R. Fink, Michael Schroeter, Roland Goldbrunner, Matthias Schmidt, Mohammad Maarouf

“…MET-PET seems to be useful for monitoring the short-term therapeutic effects of LITT, especially when patients have been pretreated with a multistep therapeutic regimen. …”
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Hyodeoxycholic acid inhibits colorectal cancer proliferation through the FXR/EREG/EGFR axis by Qiang Pang, Shansong Huang, Xiaodong Li, Jiaqing Cao

“…This study may provide a new therapeutic strategy to improve the prognosis of CRC.…”
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The dysregulation of PARP9 expression is linked to apoptosis and DNA damage in gastric cancer cells. by Yating Li, Xing Wang, Xiaolong Liu, Xiangjie Li, Jianling Zhang, Yulan Li

“…Therefore, it is imperative to explore potential therapeutic targets for gastric cancer. PARP9 is abnormally expressed in a variety of tumors and is associated with tumor cell apoptosis and DNA damage. …”
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Case report: Short-course hypofractionated radiation therapy combined with immune checkpoint inhibitors for the treatment of advanced ovarian mucinous cystadenocarcinoma by Xinan Wan, Mingxing Fang, Le Yuan, Hang Zhang, Dan Wang

“…Metastatic lymph nodes disappeared from the abdominal cavity. The therapeutic effect achieved a complete response (CR). …”
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Intraoral salivary duct cyst – A rare case report with review of literature by Hemalatha Pantham, N. Govind Raj Kumar, A. Sudarshan Kumar, M. Sowmya, Damera Srikanth

“…Interventions: The primary therapeutic intervention was the surgical excision of the cyst. …”
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The Combination Therapy with Zoledronic Acid and Propranolol Improves the Trabecular Microarchitecture and Mechanical Property in an Rat Model of Postmenopausal Osteoporosis by Deepak Kumar Khajuria, Rema Razdan, D. Roy Mahapatra

“…We conducted the present study to investigate the therapeutic effects of propranolol (PRO), alone and in combination with the antiresorptive agent ZOL, in a rat model of postmenopausal osteoporosis. …”
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CD47/SIRPα axis: bridging innate and adaptive immunity by Sjoerd H van der Burg, Anneloes van Duijn, Ferenc A Scheeren

“…In this perspective we provide an overview of recent studies showing how therapeutic blockade of the CD47/SIRPα axis improves the adaptive immune response. …”
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Advancing Insights into Large-Artery Stiffening in Humans Through the Application of Multi-omics by Marie-Joe Dib

“…LAS characterizes a high-priority therapeutic target to improve cardiovascular disease burden and associated comorbidities. …”
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The Theory of Epistemic (In)Justice in the Perspective of the Performance of Law: An Approach Based On The Concept Of Hermeneutic Therapy by Mariola Żak

“…In this paper, the assumptions of Miranda Fricker’s theory of epistemic (in)justice read in the context of the neo-Wittgensteinian philosophical trend, also called therapeutic or resolute approach, will be approximated. …”
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Epithelioid hemangioendothelioma prognosis and outcome: report of two challenging cases by Parviz Mardani, Zahra Hashempour, Reza Shahriarirad, Armin Amirian

“…Conclusions The optimal therapeutic approach for EHE remains controversial due to its unpredictable treatment response, particularly in recurrent or metastatic cases. …”
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A Potential Role of MicroRNA in the Renal Cancer and Its Tumor Microenvironment by Daniel Chikere Ali, Siva Bharath Merugu

“…Despite significant advancements in therapeutic strategies over recent decades, treatment outcomes for ccRCC patients remain suboptimal. …”
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Grewia tenax-Mediated Silver Nanoparticles as Efficient Antibacterial and Antifungal Agents by Priyanka Yadav, Monisha Singhal, Sreemoyee Chatterjee, Surendra Nimesh, Nidhi Gupta

“…All these studies concluded that GTAgNPs possess the potent antimicrobial potential and can be employed as antimicrobial therapeutic agents.…”
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Antiviral activity of an ACE2-Fc fusion protein against SARS-CoV-2 and its variants. by Ernesto Bermúdez-Abreut, Talia Fundora-Barrios, Diana Rosa Hernández Fernández, Enrique Noa Romero, Anitza Fraga-Quintero, Ana V Casadesús Pazos, Briandy Fernández-Marrero, Claudia A Plasencia Iglesias, Marilyn Clavel Pérez, Katya Sosa Aguiar, Belinda Sánchez-Ramírez, Tays Hernández

“…Our results suggest the potential of this molecule to be used in both therapeutic and preventive settings against current and emerging mutants that use ACE2 as a gateway to human cells.…”
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ZNF652-Induced circRHOT1 Promotes SMAD5 Expression to Modulate Tumorigenic Properties and Nature Killer Cell-Mediated Toxicity in Bladder Cancer via Targeting miR-3666 by Hu Ke, Jiabin Zhang, Fei Wang, Yunhe Xiong

“…These results may provide a new direction for developing novel diagnostic or therapeutic targets for BC.…”
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The significance of focal pattern in hypsarrhythmia by Anna Wiedemann, Birgit Stark, Gudrun Gröppel

“…Introduction: Infantile Epileptic Spasms Syndrome (IESS) presents a therapeutic challenge and is frequently associated with developmental delay. …”
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Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning by Yue Hu, Yating Lin, Bo Peng, Chunyan Xiang, Wei Tang

“…The recent emergence of monoclonal antibodies, including mepolizumab, reslizumab, and benralizumab, offers therapeutic promise, yet their efficacy varies due to the heterogeneous nature of asthma. …”
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PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases by Yanmei Yang, Bin Wang

“…The effects of intermittent PTH and allosteric modulators of CaSR for the use of bone-anabolic agents and prevention of BrCa bone metastases constitute a proof of principle for therapeutic consideration. Understanding the interplay between PTH1R and CaSR signaling in the development of BrCa bone metastases could lead to a novel therapeutic approach to control both osteolysis and tumor burden in the bone.…”
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