Small intestinal bacterial overgrowth in patients with systemic sclerosis by Saara Rawn, Natalia Pitman, Karen Beattie, Ava Bazzaz, Maggie Larche

“…This article reviews various diagnostic approaches and therapeutic options for SIBO. Treatment modalities mainly include prokinetics, probiotics, and antibiotics.…”
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Clinical Practice Guidelines for Cerebral Abscess Treatment by Danny Barrueta Reyes, Néstor Pulido Ríos

“…It has been defined as a festering process caused by any germ and placed inside the cerebral parenchyma; this is a diagnostic and therapeutic challenge for surgeons and general doctors since the clinical and radiological manifestations are often imprecise. …”
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Clinical Practice Guidelines for Acute Renal Failure. by Argelio Alberto Santana Cano, Marta Patricia Casanova González, Belkys Rodríguez Llerena, Eddy Pereira Valdés

“…It aetiological agents, clinical presentation, therapeutic and diagnostic methods are described. It includes assessment guidelines focused on the most important aspects to be accomplished.…”
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From bench to bedside: translational insights into aging research by Kanti Bhooshan Pandey, Kanti Bhooshan Pandey

“…This review discusses the critical translational insights that bridge the gap between bench research and bedside applications, highlighting key discoveries in the mechanisms of aging, biomarkers, and therapeutic interventions. It underscores the importance of interdisciplinary approaches and collaboration among scientists, clinicians, and policymakers to address the complexities of aging and improve health span.…”
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IL-7 is a Key Driver Cytokine in Spondyloarthritis? by Rafaela Silva Guimarães Gonçalves, Angela Luzia Branco Pinto Duarte

“…IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a better understanding of the disease as well as an important potential therapeutic target in patients with SpA.…”
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Middle Ear Welding Injury: Case Report and Literature Review by Gabriele Bruno, Elena Carlotto, Fabio Bramardi, Elisa Franco, Alessia Lanzillotta, Walter Lerda, Nertila Naqe, Silvia Ponzo

“…An exhaustive review of the literature is lacking, particularly with regard to clinical presentation, diagnostic-therapeutic work-up, and outcomes. Here we describe the clinical details of an injury caused by the largest welding foreign body ever reported in the ME. …”
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Pneumoperitoneum, Retropneumoperitoneum, Pneumomediastinum, and Diffuse Subcutaneous Emphysema following Diagnostic Colonoscopy by Evangelos Falidas, Georgios Anyfantakis, Konstantinos Vlachos, Christina Goudeli, Boutzouvis Stavros, Constantinos Villias

“…We report a case of a 78-year-old woman presented to the emergency department with abdominal pain and diffuse abdominal, chest, neck, and facial swelling appeared after a diagnostic colonoscopy. Diagnostic and therapeutic modalities are discussed.…”
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Clinical Practice Guidelines for Acute Pulmonary Edema. by Pablo Rodríguez Díaz, Juan José Navarro López, Claudio González Rodríguez, José Manuel Ercia Arenal

“…This document includes a review and update of the main clinical aspects allowing the early diagnosis and immediate therapeutic treatment. It includes assessment guidelines focused on the most important aspects to be accomplished.…”
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The Nasal Route as a Potential Pathway for Delivery of Erythropoietin in the Treatment of Acute Ischemic Stroke in Humans by Julio Cesar García-Rodríguez, Iliana Sosa Teste

“…Intranasal delivery provides a practical, noninvasive method of bypassing the blood-brain barrier (BBB) in order to deliver therapeutic agents to the brain. This method allows drugs that do not cross the BBB to be delivered to the central nervous system in a few minutes. …”
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Immune Privilege and Eye-Derived T-Regulatory Cells by Hiroshi Keino, Shintaro Horie, Sunao Sugita

“…We believe that a better understanding of the ocular immune privilege associated with Tregs might offer a new approach with regard to therapeutic interventions for ocular autoimmunity.…”
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The Theranostic Genome by Xiaoying Xu, Pablo Jané, Vincent Taelman, Eduardo Jané, Rebecca A. Dumont, Yonathan Garama, Francisco Kim, María del Val Gómez, Karim Gariani, Martin A. Walter

“…To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be utilized to combine therapeutic and diagnostic applications. Using a deep learning-based hybrid human-AI pipeline that cross-references PubMed, the Gene Expression Omnibus, DisGeNET, The Cancer Genome Atlas and the NIH Molecular Imaging and Contrast Agent Database, we bridge individual genes in human cancers with respective theranostic compounds. …”
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Acoustic Features of Vowels in Patients with Dysarthria by Jing XU, Yalin XU, Zhiwei MOU, Jianliang LU, Chenyin JIANG

“…Domestic studies on this speech disorder are mostly limited to acupuncture, electrical stimulation and other therapeutic effects, and the evaluation of the therapeutic effect is mostly subjective, involving the lack of acoustic analysis. …”
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Elucidating genetic intersections: Co-differentially expressed genes in myasthenia gravis and idiopathic inflammatory myopathies and their role in comorbid pathogenesis by Wenqu Yang, Feng Liang

“…Objective: This study aims to identify common differentially expressed genes (co-DEGs) between MG and IIM to elucidate shared pathogenic pathways and potential therapeutic targets. Methods: Transcriptomic data from the Gene Expression Omnibus (GEO) were analyzed using the ''limma'' package in RStudio. …”
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Convalescent plasma therapy in severe coronavirus disease-2019: A narrative review by Rasmi Ranjan Sahoo, Kasturi Hazarika, Prashant Bafna, Manesh Manoj, Anupam Wakhlu

“…Passive immunotherapy using whole blood or plasma from recovered patients is a potential therapeutic strategy for infections with no known drug therapy or prophylactic vaccines. …”
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Trends in research on novel antidepressant treatments by Agnieszka Zelek-Molik, Ewa Litwa

“…Such advances offer the potential for rapid therapeutic effects without the prolonged and often tedious administration of older generation antidepressants. …”
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Phosphodiesterase 4 inhibition as a novel treatment for stroke by Jiahong Zhong, Xihui Yu, Zhuomiao Lin

“…These mechanisms collectively facilitate the recovery of functional neurons, thereby serving as potential therapeutic interventions. Therefore, the comprehensive investigation of phosphodiesterase 4 as an innovative pharmacological target for stroke injury provides valuable insights into the development of therapeutic interventions in stroke treatment. …”
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The Impact of Recent Generic Drug Price Policies on Pharmaceutical Innovation: A Theoretical Rationale and Proposal of a Method Supporting Innovation in Areas of Unmet Medical Need by Pierre-Alexandre Dionne, Farzad Ali, Mendel Grobler

“…By identifying the relevant disease areas, decision makers and HTA authorities could therefore convey the importance of investing in these therapeutic areas to manufacturers.…”
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Treatment of convulsive status epilepticus in Brazil: a review by Luis Otavio Caboclo

“…In the absence of randomized controlled trials, treatment should be guided by the physician's experience, clinical judgment, and established therapeutic options from previous reports.…”
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Clinical utility of combined contrast-enhanced ultrasound and intracavitary contrast-enhanced ultrasound in the percutaneous treatment of pyogenic liver abscess by Giampiero Francica

“…During the treatment planning phase, the combined use of CEUS and IC-CEUS affected therapeutic choices (e.g., drainage technique, additional therapeutic measures) in comparison with pre-operative imaging in 66.7% of patients. …”
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Role of Farnesoid X Receptor in the Pathogenesis of Respiratory Diseases by Jin-nan Wu, Jian-rong Chen, Jin-liang Chen

“…In this article, we provide an overview of the internal relationship between FXR and respiratory diseases to track the progress that has been achieved thus far in this direction and suggest potential therapeutic prospects of FXR in respiratory diseases.…”
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