Markers of Field Cancerization: Proposed Clinical Applications in Prostate Biopsies by Kristina A. Trujillo, Anna C. Jones, Jeffrey K. Griffith, Marco Bisoffi

“…This paper tabulates markers of prostate field cancerization known to date and discusses their potential clinical value in the analysis of prostate biopsies, including diagnosis, monitoring progression during active surveillance, and assessing efficacy of presurgical neoadjuvant and focal therapeutic interventions.…”
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National Trends in Pulmonary Embolism Visit in United State Emergency Departments and Associated Costs (2006–2018) by Ahmad Aalam, Diyaa Bokhary, Awad Alsabban, Ahmad Bakhribah

“…Conclusion: From 2006 to 2018, PE ED visits in the US increased with a noticeable decrease in admission rates and length of stay, likely secondary to advancement in diagnostic and therapeutic modalities like computed tomography pulmonary angiography and novel oral anticoagulants. …”
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Frailty in Older Adults and Physical Activity by Jorge Luis Abreus Mora, Vivian Bárbara González Curbelo

“…Early detection of frailty and the timely use of diagnostic, therapeutic and rehabilitative techniques can positively modify the expected expression of disability in the elderly. …”
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A therapy inactivating the tumor angiogenic factors by Cristian Morales-Rodrigo

“…It is proved the global existence for the nonlinear system and the effect in the large time behavior of the system for high doses of the therapeutic agent.…”
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The pattern of antibiotic utilisation among intensive care unit patients hospitalised in a Gauteng (South African) provincial tertiary hospital: Comparing findings before and durin... by L Spinickum, Z Booth, S Leigh-de Rapper

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Cancer vaccines compensate for the insufficient induction of protective tumor-specific immunity of CD3 bispecific antibody therapy by Sjoerd H van der Burg, Marjolein Sluijter, Thorbald van Hall, Jim Middelburg, Kristel Kemper, Janine Schuurman, Gaby Schaap, Katy Lloyd, Vitalijs Ovcinnikovs

“…Induction of long-lasting tumor-specific immunity might therefore improve therapeutic efficacy, but has not been studied in detail yet for CD3 bsAbs. …”
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Dose-Weighted Network Pharmacology: Evaluating Traditional Chinese Medicine Formulations for Lumbar Disc Herniation by Zhou C, Xiang T, Yu Y, Ma H, Liu C, Yang F, Yang L

“…The VIKOR method was used to assess the importance of therapeutic targets, with weights assigned based on both drug and disease perspectives. …”
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A Critical Appraisal of System-Reported Organ Dose (OD) Versus Manually Calculated Mean Glandular Dose (MGD) in Dubai’s Mammography Services by Kaltham Abdulwahid Mohammad Noor, Norhashimah Mohd Norsuddin, Muhammad Khalis Abdul Karim, Iza Nurzawani Che Isa, Vaidehi Ulaganathan

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Phenolic Content and Antioxidant and Antimicrobial Activities of Malva sylvestris L., Malva oxyloba Boiss., Malva parviflora L., and Malva aegyptia L. Leaves Extract by Khalid A. Shadid, Ashok K. Shakya, Rajashri R. Naik, Nidal Jaradat, Husni S. Farah, Naeem Shalan, Nooman A. Khalaf, Ghaleb A. Oriquat

“…As such, it is emerging as a promising therapeutic agent for the treatment of various neurodegenerative diseases and many types of human infectious diseases.…”
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Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods:... by Hind A. Alkhatabi, Peter Natesan Pushparaj

“…Several drugs and natural products, including dihydroergocristine, mepacrine, gedunin, amlodipine, and disulfiram have been identified as potential therapeutic agents for reversing AD-associated gene signatures. …”
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Multi-omics and machine learning-driven CD8+ T cell heterogeneity score for head and neck squamous cell carcinoma by Di He, Zhan Yang, Tian Zhang, Yaxian Luo, Lianjie Peng, Jiatao Yan, Tao Qiu, Jingyu Zhang, Luying Qin, Zhichao Liu, Mouyuan Sun

“…These findings suggest that simvastatin and pazopanib could open up innovative potential therapeutic avenues for individuals with HNSCC.…”
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Uptake of Single-Walled Carbon Nanotubes Conjugated with DNA by Microvascular Endothelial Cells by Joseph Harvey, Lifeng Dong, Kyoungtae Kim, Jacob Hayden, Jianjie Wang

“…The findings demonstrate that SWCNTs facilitate DNA delivery into microvascular ECs, thus suggesting that SWCNTs serving as drug and gene vehicles have therapeutic potential.…”
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Oligodendrocyte Injury in Multiple Sclerosis. by Mateo Përgjegji, Klei Bame, Ketrina Ceka, Jera Cenalia , Sibora Bërdica , Teona Bushati

“…This research paper explores the multifaceted aspects of oligodendrocyte injury in MS, ranging from underlying pathophysiological mechanisms to potential therapeutic interventions and translational implications for clinical practice. …”
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Little strokes fell big oaks: The use of weak magnetic fields and reactive oxygen species to fight cancer by Margit Egg, Thomas Kietzmann

“…While WEMF have been used therapeutically for musculoskeletal disorders for decades, their role in oncology is still emerging. …”
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Psychological assessment and support in functional neurological disorder: a longitudinal study by Yvonne Radin, Matteo Bulfon, Paola Caruso, Egidio Barbi, Paolo Manganotti, Andrea Clarici

“…This comparison sought to identify any alignment or discrepancies in the perception of symptoms and therapeutic progress, as measured by both the ANPS and SWAP-200 scales. …”
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Benefit from the Chin-Down Maneuver in the Swallowing Performance and Self-Perception of Parkinson’s Disease Patients by Annelise Ayres, Geraldo Pereira Jotz, Carlos R. M. Rieder, Maira Rozenfeld Olchik

“…Both groups (EG and OG) received on-month therapeutic program. Results. A significant improvement in swallowing, evaluated by clinical assessment, was observed in solid (p<0.001) and liquid (p=0.022) consistencies in EG when compared to OG and CG. …”
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Oral administration of pioglitazone inhibits pulmonary hypertension by regulating the gut microbiome and plasma metabolome in male rats by Zizhou Zhang, Yaru Liang, Shaocong Mo, Mingming Zhao, Yi Li, Chenting Zhang, Xiaoqian Shan, Shiyun Liu, Jing Liao, Xiaoyun Luo, Junqi Zhu, Chen Wang, Qian Jiang, Chi Hou, Wei Hong, Ning Lai, Yuqin Chen, Lei Xu, Wenju Lu, Jian Wang, Zhongfang Wang, Kai Yang

“…The data also supports that modulation of gut microbiota by supplementation of selective probiotics could be a novel effective therapeutic strategy for the treatment of PH.…”
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Performance of a Two-Week Rehabilitation Improves Motor Function in Inpatients with Progressive Supranuclear Palsy: A Pre–Post Study by Naomi Matsuda, Yasuyuki Takamatsu, Makoto Sawada, Ikuko Aiba

“…Rehabilitation is an important therapeutic approach for motor dysfunction in patients with PSP. …”
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Engineered bacterial membrane biomimetic covalent organic framework as nano-immunopotentiator for cancer immunotherapy by Qi-Chao Yang, Yuan-Yuan Wang, Shuo Wang, An Song, Wen-Da Wang, Liang Zhang, Zhi-Jun Sun

“…In summary, this innovative approach not only enhances the therapeutic potential of COFs but also opens up new avenues for integrating microbial and nanotechnological strategies in cancer treatment.…”
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Revolutionizing oral care: Reactive oxygen species (ROS)-Regulating biomaterials for combating infection and inflammation by Wei Zhao, Yu Zhang, Jing Chen, Danrong Hu

“…This review provides novel insights for the ongoing development of ROS-based therapeutic strategies for oral diseases.…”
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