Role of Probiotics in the Management of Patients with Ulcerative Colitis and Pouchitis by Francesca Bernardi, Fabrizio Fanizzi, Tommaso Lorenzo Parigi, Alessandra Zilli, Mariangela Allocca, Federica Furfaro, Laurent Peyrin-Biroulet, Silvio Danese, Ferdinando D’Amico

“…Understanding the role of the microbiota in pouch health has spurred interest in probiotics as a therapeutic strategy. Probiotics represent a promising avenue in the management of pouchitis, offering a natural and targeted approach to improving outcomes for UC patients. …”
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Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting by Sofiia N. Rizatdinova, Alina E. Ershova, Irina V. Astrakhantseva

“…Such tools facilitated the search for potential therapeutic agents and accelerated epidemiological studies on post-infection and post-vaccination humoral immunity. …”
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Regulatory Effect of Mesenchymal Stem Cells on T Cell Phenotypes in Autoimmune Diseases by Zhiping Wei, Jintao Yuan, Gaoying Wang, Dickson Kofi Wiredu Ocansey, Zhiwei Xu, Fei Mao

“…Therefore, the therapeutic potential of MSCs in various diseases including autoimmune conditions has been explored. …”
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Targeting TLR/IL-1R Signalling in Human Diseases by Maria Loiarro, Vito Ruggiero, Claudio Sette

“…On the other hand, an aberrant activation of TLR/IL-1R signalling can promote the onset of inflammatory and autoimmune diseases, raising the interest in the development of therapeutic strategies for the control of their function. …”
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IL-18 biology in severe asthma by Sarita Thawanaphong, Sarita Thawanaphong, Sarita Thawanaphong, Aswathi Nair, Aswathi Nair, Emily Volfson, Emily Volfson, Parameswaran Nair, Parameswaran Nair, Manali Mukherjee, Manali Mukherjee

“…By synthesizing recent advancements and ongoing research, this review underscores the importance of IL-18 as a potential novel therapeutic target in the treatment of severe asthma and other related conditions.…”
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Gen inhibiting the Wnt/Ca2+ signaling pathway alleviates cerebral ischemia/reperfusion injury by Li Li, Saisai Liu, Mengzhe Wang, Mengjia Li, Yi Liu, Haili Chen, Jie Chen, Weiting Tao, Li Huang, Shidi Zhao

“…In this study, we investigated the therapeutic potential of Genistein (Gen) in alleviating CIRI by focusing on its effects on the Wnt/Ca2+ signaling pathway. …”
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Extracellular Vesicles as Tools for Crossing the Blood–Brain Barrier to Treat Lysosomal Storage Diseases by Giovanni Lerussi, Verónica Villagrasa-Araya, Marc Moltó-Abad, Mireia del Toro, Guillem Pintos-Morell, Joaquin Seras-Franzoso, Ibane Abasolo

“…This review highlights the unique properties of EVs, such as their biocompatibility, capacity to cross the blood–brain barrier (BBB), and potential for therapeutic cargo loading, including that of enzymes and genetic material. …”
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Strategies to Enhance Mesenchymal Stem Cell-Based Therapies for Acute Respiratory Distress Syndrome by Jibin Han, Yanmin Li, Yuanyuan Li

“…To provide a comprehensive and updated view, we summarize a large body of experimental evidence for a variety of strategies directed towards strengthening the therapeutic potential of MSCs in ARDS.…”
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miR-155: An Important Role in Inflammation Response by Jingyan Hu, Songli Huang, Xiaoli Liu, Yuan Zhang, Shengli Wei, Xiuhua Hu

“…The widespread involvement of miR-155 in human diseases has led to a novel therapeutic approach between Chinese and Western medicine.…”
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Study on the regulatory mechanisms of mitochondrial biosynthesis by polyoxometalates by Shan Lei, Bingnian Chen, Li Wang, Jian Li

“…In recent years, polyoxometalates (POMs) have been extensively researched for their potential in treating diabetes, tumors, cancer, inflammation, and other diseases, both in vitro and in vivo. Their primary therapeutic mechanisms are related to the generation of reactive oxygen species (ROS), leading to oxidative stress. …”
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Leukocyte Production of Inflammatory Mediators Is Inhibited by the Antioxidants Phloretin, Silymarin, Hesperetin, and Resveratrol by Jezrom B. Fordham, Afsar Raza Naqvi, Salvador Nares

“…Antioxidants possess significant therapeutic potential for the treatment of inflammatory disorders. …”
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Treatment of Acute Graft-versus-Host Disease in Liver Transplant Recipients by Edward Kim, Alina Adeel, Adel Bozorgzadeh, Shinya Amano, Curtis T. Barry, Jennifer S. Daly, Deepika Devuni, Zendee Elaba, Laura Houk, Paulo N. Martins, Babak Movahedi, Muthalagu Ramanathan, Nicole M. Theodoropoulos

“…We reviewed the literature to discuss various therapeutic options currently available for aGvHD after liver transplantation.…”
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Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice by Cheukyau Luk, Katherine I. Bridge, Nele Warmke, Katie J. Simmons, Michael Drozd, Amy Moran, Amanda D. V. MacCannell, Chew W. Cheng, Sam Straw, Jason L. Scragg, Jessica Smith, Claire H. Ozber, Chloe G. Wilkinson, Anna Skromna, Natallia Makava, Hiran A. Prag, T. Simon Futers, Oliver I. Brown, Alexander-Francisco Bruns, Andrew MN Walker, Nicole T. Watt, Romana Mughal, Kathryn J. Griffin, Nadira Y. Yuldasheva, Sunti Limumpornpetch, Hema Viswambharan, Piruthivi Sukumar, David J. Beech, Antonio Vidal-Puig, Klaus K. Witte, Michael P. Murphy, Richard C. Hartley, Stephen B. Wheatcroft, Richard M. Cubbon, Lee D. Roberts, Mark T. Kearney, Natalie J. Haywood

“…Remodelling adipose tissue as a therapeutic goal for obesity and its complications has attracted much attention and continues to be actively explored. …”
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Chemotherapy in the Setting of Severe Liver Dysfunction in Patients with Metastatic Colorectal Cancer by Pashtoon Murtaza Kasi, Gita Thanarajasingam, Heidi D. Finnes, Jose C. Villasboas Bisneto, Joleen M. Hubbard, Axel Grothey

“…Based on the divergent experience of treating 2 cases and other prior reports, a summary of recommendations with a model in the form of a “therapeutic triad” is presented. The paper highlights the therapeutic challenges in patients with mCRC and severe liver dysfunction. …”
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Myocardial Regeneration via Progenitor Cell-Derived Exosomes by Janita A. Maring, Christien M. Beez, Volkmar Falk, Martina Seifert, Christof Stamm

“…Despite initial enthusiasm, therapeutic efficacy has overall been disappointing, and clinical application is costly and complex. …”
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Novel Strategies for the Improvement of Stem Cells’ Transplantation in Degenerative Retinal Diseases by Simona Delia Nicoară, Sergiu Șușman, Oana Tudoran, Otilia Bărbos, Gabriela Cherecheș, Simion Aștilean, Monica Potara, Olga Sorițău

“…Currently, there is no cure for the permanent vision loss caused by degenerative retinal diseases. One of the novel therapeutic strategies aims at the development of stem cells (SCs) based neuroprotective and regenerative medicine. …”
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Exploring the promising impacts of naringin and its aglycone constituent naringenin as major citrus flavonoids on diabetes and its complications by Soroush Fotouhi, Aida Yavari, Amir Reza Bagheri, Vahid Reza Askari, Yazdan Gholami, Vafa Baradaran Rahimi

“…Naringin and naringenin could be developed as novel therapeutic options for treating DM, and the knowledge acquired from this review could be a valuable tool for future research projects.…”
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GH Therapy in Non–Growth Hormone-Deficient Children by Chiara Guzzetti, Anastasia Ibba, Valeria Incandela, Sandro Loche

“…Before 1985, growth hormone (GH) was extracted from human pituitaries, and its therapeutic use was limited to children with severe GH deficiency (GHD). …”
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Model bimbingan dan konseling menggunakan cinematherapy untuk mereduksi keyakinan negatif by Nikmarijal Nikmarijal, Cece Rakhmat, Ahman Ahman, Nandang Rusmana, Ifdil Ifdil

“…Cinematherapy is defined as an umbrella term for a therapeutic process that involves the assignment of films to clients in order to promote and enhance therapeutic benefits. …”
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Surgical Orthodontic Treatment of an Impacted Canine in the Presence of Dens Invaginatus and Follicular Cyst by Marialuce Spallarossa, Carola Canevello, Francesca Silvestrini Biavati, Nicola Laffi

“…When treating a dens invaginatus there are different therapeutic solutions: they depend on the gravity of the anomaly and on the association with the retention of a permanent tooth. …”
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