The multifaceted roles of cathepsins in immune and inflammatory responses: implications for cancer therapy, autoimmune diseases, and infectious diseases by Kexin Zhao, Yangqing Sun, Shangwei Zhong, Jun-Li Luo

“…In this review, we systematically examine the impact of cathepsins on the immune system and their mechanistic roles in cancer, infectious diseases, autoimmune and neurodegenerative disorders, with the goal of identifying novel therapeutic strategies for these conditions.…”
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C-Lobe of Lactoferrin: The Whole Story of the Half-Molecule by Sujata Sharma, Mau Sinha, Sanket Kaushik, Punit Kaur, Tej P. Singh

“…This review provides the details of the proteolytic preparation of C-lobe, and interspecies comparisons of its sequence and structure, as well as the scope of its therapeutic applications.…”
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Revolution in cancer treatment methods: Perspective review of factors affecting the final results of nanoparticles used in magnetic fluid hyperthermia by P. Rastgoo Oskoui, M. Rezvani

“…Recent advances in nanotechnology have made magnetic fluid hyperthermia a potential therapeutic platform for cancer treatment. Magnetic fluid hyperthermia can be used alone or in combination with other conventional therapeutic methods such as chemotherapy, radiotherapy, etc. …”
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B Cells in Autoimmune Diseases by Christiane S. Hampe

“…This new understanding of the role of B cells opened up novel therapeutic options for the treatment of autoimmune diseases. …”
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The Effects of Hypoxia on the Immune-Modulatory Properties of Bone Marrow-Derived Mesenchymal Stromal Cells by Zsolt Fábián

“…This urges the development of more efficient therapeutic modalities like the mesenchymal stem cell-based approaches. …”
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Psychosynthesis in Positive Psychotherapy by Zlatoslav Arabadzhiev, Stefanka Tomcheva

“…This synthesis broadens the scope of therapeutic applications, enhancing client-centered, flexible, and effective interventions. …”
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Factors associated with caffeine intake among undergraduates: a cross-sectional study from Palestine by May Hamdan, Souzan Zidan, Fatima Al-Amouri, Hiba Niroukh, Manar Abu Dawod, Sajeda Ashour, Shahd Sameer Dweik, Manal Badrasawi

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How a gene fuels ear infections by Sedigheh Delmaghani, Aziz El-Amraoui

“…The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.…”
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Externally validated nomogram for predicting short-term pregnancy outcome of singleton pregnancies with fetal growth restriction (FGR) by Yang Li, Xiaohong Zhang, Junshu Xie, Fufen Yin, Mingrui Jin, Yujing Li, Xiuju Yin

“…Encouragingly, consistent results were observed in the external validation set, with a C-index of 0.776 (95% CI: 0.71 to 0.84) for predicting TOP, which included intrauterine fetal death and therapeutic lethal induction, with a C-index of 0.773 (95% CI: 0.70 to 0.84) for predicting stillbirth, and a C-index of 0.776 (95% CI: 0.70 to 0.85) for predicting therapeutic lethal induction with indications. …”
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Faster onset of action with topical levocabastine than with oral cetirizine by Michel A. Drouin, William H. Yang, Frederick Horak

“…At 8 h there were no differences between the two treatments. Overall therapeutic efficacy was found to be comparable in the two treatment groups over the 2-week study period with no significant intergroup differences in symptom severity or global therapeutic efficacy. …”
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Investigating the Prognostic and Oncogenic Roles of Membrane-Associated Ring-CH-Type Finger 9 in Colorectal Cancer by Jiayan Zhang, Qinghan Jiao, Zhigang Chen

“…Further research is essential to elucidate precise mechanisms by which MARCHF9 enhances tumorigenesis and to explore its therapeutic potential in CRC management.…”
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Treatment with Herbal Formula Extract in the hSOD1G93A Mouse Model Attenuates Muscle and Spinal Cord Dysfunction via Anti-Inflammation by Eun Jin Yang, Sun Hwa Lee, Mudan Cai

“…HFE-treated hSOD1G93A mice showed increased anti-inflammation, antioxidation, and regulation of autophagy in the muscles and spinal cord. Thus, HEF can be therapeutic candidates for inhibiting disease progression in patients with ALS. …”
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To Measure or Not to Measure: Direct Oral Anticoagulant Laboratory Assay Monitoring in Clinical Practice by Tania Ahuja, Veronica Raco, Sharonlin Bhardwaj, David Green

“…The need for therapeutic drug monitoring of direct oral anticoagulants (DOACs) remains an area of clinical equipoise. …”
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Dioscin pretreatment ameliorates ferroptosis in cardiomyocytes after myocardial infarction via inhibiting endoplasmic reticulum stress by Chang Wu, Xueping Shen, Pan Lou, Dongyan Song

“…Conclusion Overall, our findings suggested that Dioscin holds promise as a therapeutic agent against post-MI cardiac injury by mitigating ferroptosis via the suppression of ER stress. …”
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Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…This study examines the therapeutic potential of etoricoxib nanostructured lipid carriers (ETO-NLC) in mitigating radiation-induced ovarian damage in female <i>Wistar</i> rats. …”
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Investigation of the Physical Properties of Different Ion Species at Hadron Therapy; A Comprehensive Study by Ahmad Esmaili Torshabi

“… Purpose: Recently, using hadrons as a therapeutic beam has been highly advised for radiation treatment of mainly deep-seated tumors due to the desired conforming of three-dimensional dose conformation onto tumor volume. …”
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Epidemiology of spinal cord injuries in three selected counties in Kenya by George M. Muli, Veronica Ntsiea, Natalie Benjamin-Damons, Nassib Tawa

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Gut microbiota and atrial cardiomyopathy by Tingting Sun, Beibei Song, Bo Li

“…We also discuss how diet and exercise affect atrial cardiomyopathy by influencing the gut microbiota, as well as possible future therapeutic approaches targeting the gut–heart axis. …”
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Single-Use Flexible Bronchoscope in Facilitating Endobronchial Valve Treatment in Severe Emphysema by Sakaguchi T, Slebos DJ

“…The use of single-use therapeutic bronchoscopes with greater flexibility than conventional reusable therapeutic bronchoscopes may be a valuable approach for achieving successful EBV placement in anatomically challenging cases with sharp bronchial branching angles. …”
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Effect of Premna pubescens Ethanol Extract on Erythrocyte Count and Kidney Histology in Rattus norvegicus L by Srinatalia Silaen

“…This study aimed to investigate the potential therapeutic effects of the ethanol extract of Premna pubescens leaves on erythrocyte count and kidney histology in Rattus norvegicus L. …”
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