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3481
Overcoming β-Cell Dysfunction in Type 2 Diabetes Mellitus: CD36 Inhibition and Antioxidant System
Published 2025-01-01“…Additionally, novel insights into the glutathione antioxidant system and its role in β-cell survival underscore its therapeutic potential. This review focuses on the key contribution of oxidative stress and CD36 to β-cell impairment, the therapeutic promise of antioxidants, and the need for further research to apply these findings in clinical practice. …”
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3482
Ethnomedicinal, Pharmacological, and Phytochemical Overview of Diplazium esculentum
Published 2025-01-01“…Evaluation of the safety profile through animal studies and clinical trials underscores its potential as a safe therapeutic agent albeit with considerations for dosage and administration. …”
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3483
Medicinal Use of Cannabis: History and Current Status
Published 2001-01-01“…OBJECTIVE: To provide an overview of the history and pharmacology of cannabis in relation to current scientific knowledge concerning actual and potential therapeutic uses of cannabis preparations and pure cannabinoids.…”
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3484
Exploring the dielectric properties of herbal medicine and modern pharmaceuticals: an integrative review
Published 2025-01-01“…This approach enables the development of innovative therapeutic solutions that address safety and efficacy challenges. …”
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3485
Extracorporeal shock wave therapy versus dexamethasone iontophoresis as a treatment for symptomatic knee osteoarthritis
Published 2024-12-01“…Conclusions ESWT has a superior therapeutic effect in patients with symptomatic KOA.…”
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3486
An “Engram-Centric” Approach to Transient Global Amnesia (TGA) and Other Acute-Onset Amnesias
Published 2025-01-01“…This analysis affords therapeutic implications for these conditions, should interventions to reactivate latent or silent engrams become available.…”
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3487
Intravitreal Brolucizumab for Choroidal Neovascularization Associated to Angioid Streaks
Published 2022-01-01“…In conclusion, intravitreal brolucizumab (IB) is an efficacious and safe therapeutic option for the management of CNV secondary to AS. …”
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3488
Current Status of Mechanical Circulatory Support: A Systematic Review
Published 2012-01-01“…Although heart transplantation still represents the gold standard therapeutical approach, the implantation of mechanical circulatory support devices (MCSDs) evolved to a well-established management for this disease. …”
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3489
Local electrical stimulation: introduction to the problem
Published 2025-02-01“… The term "local electrical stimulation" means the delivery, for therapeutic purposes, of electric current signals in the areola of the projections of acupuncture points. …”
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3490
Exploring the diversity of cannabis cannabinoid and non-cannabinoid compounds and their roles in Alzheimer's disease: A review
Published 2025-06-01“…Cannabis sativa is recognized for its chemical diversity and therapeutic potential, particularly in addressing neurodegenerative diseases such as Alzheimer's disease (AD). …”
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3491
HSF1 at the crossroads of chemoresistance: from current insights to future horizons in cell death mechanisms
Published 2025-01-01“…This review comprehensively examines HSF1’s role in chemoresistance and its potential as a therapeutic target in cancer. We explore the complex, intricate mechanism that regulates the activation of HSF1, HSF1’s function in promoting resistance to chemotherapy, and the strategies used to manipulate HSF1 for therapeutic benefit. …”
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3492
The Function of Necroptosis and Its Treatment Target in IBD
Published 2024-01-01“…Eventually, understanding the pathogenesis of necroptosis in IBD will enable the development of additional therapeutic approaches for the illness.…”
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3493
Role of Coagulation Factors in Hepatocellular Carcinoma: A Literature Review
Published 2024-12-01“…In addition, this review highlights the underlying mechanisms linking coagulation pathways to HCC pathogenesis and explores potential therapeutic targets. An integrative perspective on the role of coagulation markers in HCC may improve clinical management strategies for patients affected by this malignancy.…”
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3494
Alternative Argets Within the Endocannabinoid System for Future Treatment of Gastrointestinal Diseases
Published 2011-01-01“…Drugs that inhibit endocannabinoid degradation and raise the level of endocannabinoids are becoming increasingly promising alternative therapeutic tools to manipulate the ECS.…”
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3495
Peroxisome Proliferator-Activated Receptors in Lung Cancer
Published 2007-01-01“…Consequently, intense research is being conducted in this area with the hope of discovering new PPAR-related therapeutic targets for the treatment of lung cancer. …”
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3496
A Review of Dual-Task Walking Deficits in People with Parkinson's Disease: Motor and Cognitive Contributions, Mechanisms, and Clinical Implications
Published 2012-01-01“…However, effective therapeutic interventions for dual-task walking deficits are limited. …”
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3497
Global Cardiovascular Risk Assessment in the Management of Primary Hypertension: The Role of the Kidney
Published 2013-01-01“…Thanks to their relatively low cost and wide applicability, more widespread use of these tests in the diagnostic workup will help detect subsets of patients at greater risk for whom additional preventive and therapeutic treatment is advisable.…”
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3498
Novel Interventional Approaches for ALI/ARDS: Cell-Based Gene Therapy
Published 2011-01-01“…Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS), continue to be a major cause of morbidity and mortality in critically ill patients. The present therapeutic strategies for ALI/ARDS including supportive care, pharmacological treatments, and ventilator support are still controversial. …”
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3499
Drug screening for ischemic stroke using larvae and adult zebrafish model: a review
Published 2025-01-01“…Abstract Ischemic stroke (IS) is the most recorded case of stroke that is caused by decreased blood flow to the brain. Nowadays, therapeutical agents for IS are limited and they have not shown maximum clinical results. …”
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3500
Current Pharmacologic Approaches for Prevention and Treatment of Bronchopulmonary Dysplasia
Published 2012-01-01“…Several preventive and therapeutic strategies have been developed with variable success. …”
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