The Link Between Gut Microbiota and Depression: Exploring the Correlation by Adam Juśkiewicz, Olga Grelewicz, Natalia Kucy, Elwira Servaas, Mateusz Haber, Paula Kula, Adrianna Czachor, Alicja Kotula

“…Further research is needed to optimize therapeutic approaches, explore personalized medicine strategies based on individual microbiome profiles and clarify the safety and efficacy of microbial-based therapies in clinical settings. …”
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Synthesis of Closely‐Contacted Cu2O‐CoWO4 Nanosheet Composites for Cuproptosis Therapy to Tumors With Sonodynamic and Photothermal Assistance by Zhuoran Yang, Zhuo Li, Chunyu Yang, Li Meng, Wei Guo, Liqiang Jing

“…Abstract Cuproptosis offers a promising and selective therapeutic strategy for cancer therapy. To fully realize its potential, the development of novel cuproptosis therapeutic agents and the achievement of efficient copper release are critical steps forward. …”
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Curcumin-Based Nanoparticles: Advancements and Challenges in Tumor Therapy by Hicham Wahnou, Riad El Kebbaj, Bertrand Liagre, Vincent Sol, Youness Limami, Raphaël Emmanuel Duval

“…Despite its promising therapeutic potential, its poor bioavailability, rapid metabolism, and low water solubility hinder curcumin’s clinical application. …”
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Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response by Arpita Balakrishnan, Arpita Balakrishnan, Gabriela Winiarek, Olga Hołówka, Jakub Godlewski, Agnieszka Bronisz

“…Furthermore, we discuss the implications of these mechanisms in developing therapeutic strategies, particularly for cancer immunotherapy. …”
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Non-melanoma skin cancer treated with hypofractionated 192—Ir contact brachitherapy: a single institution series by Elisa Ciurlia, Bianca Santo, Maria Cristina Barba, Elisa Cavalera, Paola De Franco, Sara De Matteis, Giuseppe Di Paola, Angela Leone, Antonella Papaleo, Dino Rubini, Donatella Russo, Giuseppe Rubini, Angela Sardaro

“…The two main subtypes of NMSC are basal cell carcinoma(BCC) and squamous cell carcinoma(SCC). Therapeutic management of NMSC includes a variety of options, such as surgery, radiotherapy, and topical or systemic treatments. …”
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The Notch Pathway in Breast Cancer Progression by Emmanuel N. Kontomanolis, Sofia Kalagasidou, Stamatia Pouliliou, Xanthoula Anthoulaki, Nikolaos Georgiou, Valentinos Papamanolis, Zacharias N. Fasoulakis

“…The already applied therapeutic inhibition of Notch for breast cancer can drastically change the course of the disease. …”
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Anti-Inflammatory Effects of Ellagic Acid on Acute Lung Injury Induced by Acid in Mice by Daniely Cornélio Favarin, Maxelle Martins Teixeira, Ednéia Lemos de Andrade, Claudiney de Freitas Alves, Javier Emilio Lazo Chica, Carlos Artério Sorgi, Lúcia Helena Faccioli, Alexandre Paula Rogerio

“…Together, these findings identify ellagic acid as a potential therapeutic agent for ALI-associated inflammation.…”
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Advances in Pure Drug Self-Assembled Nanosystems: A Novel Strategy for Combined Cancer Therapy by Runyan Niu, Xuexue Liu, Xian Yang, Xiao Du, Siliang Wang, Xiaolong Ma, Shaoping Yin, Lihua Shao, Jinping Zhang

“…Subsequently, the review addresses the therapeutic potential of PDANSs in combination treatment modalities, encompassing diagnostic and therapeutic applications. …”
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Liver diseases: epidemiology, causes, trends and predictions by Can Gan, Yuan Yuan, Haiyuan Shen, Jinhang Gao, Xiangxin Kong, Zhaodi Che, Yangkun Guo, Hua Wang, Erdan Dong, Jia Xiao

“…Additionally, this review offers updates on innovative diagnostic techniques, current treatments, and potential therapeutic targets presently under clinical evaluation. …”
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Inhibition of macrophage polarization and pyroptosis in collagen-induced arthritis through MSC-exo and ginsenoside Rh2 by Zhongsheng Zhou, Shuhui Wu, Yang Li, Pu Shao, Jinlan Jiang

“…In the rat arthritis model, the combination of MSC-exo and Rh2 showed synergistic therapeutic effects. Conclusion This research contributes to a deeper understanding of RA’s pathogenesis and presents new potential targeted therapeutic interventions. …”
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Hematopoietic stem cell discovery: unveiling the historical and future perspective of colony-forming units assay by Nur Afizah Yusoff, Zariyantey Abd Hamid, Siti Balkis Budin, Izatus Shima Taib

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Integrative analyses of mendelian randomization and bioinformatics reveal casual relationship and genetic links between COVID-19 and knee osteoarthritis by Xiao Zheng, Jinhao Li, Qinfeng Ma, Jianping Gong, Jianbo Pan

“…Subsequent analyses, including transcriptional regulation analysis, immune cell infiltration analysis, single-cell analysis, and druggability evaluation, were performed to explore potential mechanisms and prioritize therapeutic targets. Results The results indicate that COVID-19 has a one-way impact on KOA, while URTI does not play a causal role in this association. …”
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The influence of COVID-19 pandemic on secondary prevention in non-COVID patients with cardioembolic stroke by Lučić-Prokin Aleksandra L., Bogdanović Milan M., Pustahija Tatjana L., Stamenković Marija S.

“…Over a five-year period, data of the possible complications of therapeutic management for secondary stroke prevention were collected. …”
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Molecular dynamics simulation based prediction of T-cell epitopes for the production of effector molecules for liver cancer immunotherapy. by Sidra Zafar, Yuhe Bai, Syed Aun Muhammad, Jinlei Guo, Haris Khurram, Saba Zafar, Iraj Muqaddas, Rehan Sadiq Shaikh, Baogang Bai

“…The current treatments are only effective in early stages of cancer. To overcome the therapeutic challenges and exploration of immunotherapeutic options, broad spectral therapeutic vaccines could have significant impact. …”
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To interpret and analyze the changing patterns of histology and direct immunofluorescence findings in membranoproliferative glomerulonephritis by Pragnya P. Nayak, Pranati Pradhan, Dilleswari Pradhan, Nachiketa Mohapatra, Sarojini Raman, Pranabandhu Sahoo

“…The proposed regrouping lent therapeutic and prognostic support in managing the disease of MPGN. …”
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Influence of Moxifloxacin on Hepatic Redox Status and Plasma Biomarkers of Hepatotoxicity and Nephrotoxicity in Rat by Ayokanmi Ore, Ebenezer Tunde Olayinka

“…Overall, our data suggest that the half-therapeutic, therapeutic, and twice the therapeutic dose of MXF induced nephrotoxicity, hepatotoxicity, and altered hepatic redox balance in rats.…”
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CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA by Ugo Testa, Simona Sica, Elvira Pelosi, Germana Castelli, Giuseppe Leone

“…For B-ALL patients who relapse early after allo-HSCT or those with insufficient T-cell numbers for an autologous approach, using T cells from the original stem cell donor offers the opportunity for the successful generation of CAR-T cells and for an effective therapeutic approach. Finally, recent studies have introduced allogeneic CAR-T cells generated from healthy donors or unmatched, which are opportunely manipulated with gene editing to reduce the risk of immunological incompatibility, with promising therapeutic effects. …”
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An analysis of trace element by atomic absorption in samples of human milk collected in Amapá’s Bank of Milk by Danilo Monteiro Monteiro, Roberto Bezerra Messias

“…After quantifying these levels, the milk could have been used for therapeutic treatments for infants who have a certain mineral deficiency. …”
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Bile Acids and the Microbiome: Making Sense of This Dynamic Relationship in Their Role and Management in Crohn’s Disease by Aditi Kumar, Hafid O. Al-Hassi, Helen Steed, Oliver Phipps, Matthew J. Brookes

“…Further research should focus on targeting these areas for future therapeutic options.…”
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Antioxidant and Neuroproliferative Effects of THL-3-PTD5 Peptide Derived from Hydramacin-1 Antimicrobial Peptide by Ping-Chien Lee, Ching-Chun Lin, Hui-Hsuan Hsu, Feng-Di T. Lung

“…This study suggests that THL-3-PTD5 may serve as a potential candidate for developing therapeutic agents against neurodegenerative diseases.…”
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