Unveiling the Emerging Role of Xanthine Oxidase in Acute Pancreatitis: Beyond Reactive Oxygen Species by Chenxia Han, Yaling Wu, Juan Rong, Qing Xia, Dan Du

“…Although significant progress has been made in the previous decade, the study of mechanisms and therapeutic strategies is still far from being completed. …”
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Dental Mesenchymal Stem/Stromal Cells and Their Exosomes by Peter Stanko, Ursula Altanerova, Jana Jakubechova, Vanda Repiska, Cestmir Altaner

“…We conclude that exosomes derived from these cells are potent therapeutic tools for regenerative medicine in the near future as clinical administration of DP-MSC-conditioned medium and/or exosomes is safer and more practical than stem cells.…”
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It’s about TIME – Gal-9 as a potential immunotherapeutic target in pancreatic ductal adenocarcinoma by Christin Knickmeier, Gaetan Aime Noubissi Nzeteu, Bernhard F. Gibbs, Frederik J. H. Hoogwater, Maarten W. Nijkamp, Maximilian Bockhorn, N. Helge Meyer

“…Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by an extremely poor prognosis and limited therapeutic options. Central to the progression and immune evasion of PDAC is the tumor (immune) microenvironment (TIME), where immune checkpoint proteins such as galectin-9 (Gal-9) play pivotal roles. …”
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Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

“…Conclusions: NSAIDs are promising therapeutic alternatives in cancer treatment, offering significant chemopreventive and therapeutic benefits. …”
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The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome by Lan Luo, Xiaoli Zhuang, Lin Fu, Ziyuan Dong, Shuyuan Yi, Kan Wang, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei

“…Glycolytic reprogramming regulates NLRP3 inflammasome activation. Therapeutic potential of targeting glycolytic reprogramming to inhibit NLRP3 inflammasome activation in ALI/ARDS.…”
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Stimuli-responsive supramolecular hydrogels for paclitaxel delivery: Progress and prospects by Mohammad Qutub, Amol Tatode, Jayshree Taksande, Tanvi Premchandani, Milind Umekar, Ujban Md Hussain, Dinesh Biyani, Dadaso Mane

“…Advances in hydrogel formulations, including dual stimuli-responsive systems and nanocrystal-loaded designs, enhance drug stability, controlled release, and therapeutic efficacy. Additionally, these hydrogels can incorporate multimodal therapeutic agents, such as immunomodulators and photosensitizers, achieving synergistic anticancer effects. …”
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Recanalization Therapies in Acute Ischemic Stroke: Pharmacological Agents, Devices, and Combinations by Vijay K. Sharma, Hock Luen Teoh, Lily Y. H. Wong, Jie Su, Benjamin K. C. Ong, Bernard P. L. Chan

“…Recent studies have demonstrated safety as well as efficacy of IV-TPA even in an extended therapeutic window. However, the short therapeutic window, low rates of recanalization, and only modest benefits with IV-TPA have prompted a quest for alternative approaches to restore blood flow in an occluded artery in acute ischemic stroke. …”
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Andrographolide suppresses cervical cancer progression by targeting angiogenesis and inducing apoptosis in a CAM-PDX model by Wanwan Zou, Jun Lou, Yun Yi, Yiming Cui, Xiaoyan Chu

“…This study explores the therapeutic potential of andrographolide (AND), a bioactive compound derived from Andrographis paniculata, in mitigating cervical cancer progression using the chick embryo chorioallantoic membrane patient-derived xenograft (CAM-PDX) model. …”
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Cutting-Edge Advances in Anticancer Therapies: Insights from the Third Edition of the Special Issue “Novel Anticancer Strategies” by Hassan Bousbaa

“…Cancer incidence and mortality continue to rise at an alarming rate worldwide, underscoring the urgent need for more effective therapeutic interventions [...]…”
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Predictive Assessment of the Antiviral Properties of Imperata cylindrica against SARS-CoV-2 by Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu

“…The need for alternative therapeutic options cannot be overemphasized. Plants and their phytochemicals present interesting characteristics that make them suitable candidates for the development of antiviral therapeutic agents. …”
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Photodynamic therapy for oral cancer: Mechanisms, efficacy, and clinical applications by Shyamaladevi Babu, Madhan Krishnan

“…Photodynamic therapy (PDT) has emerged as a promising therapeutic approach for oral cancer, characterized by its ability to selectively target malignant cells while minimizing damage to surrounding healthy tissues. …”
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Valbenazine for the Treatment of Adults with Tardive Dyskinesia by Harshit Gupta, Alycee R. Moity, Allison Jumonville, Sarah Kaufman, Amber N. Edinoff, Alan D. Kaye

“…A primarily oral movement disorder induced by chronic exposure to certain classes of medications, tardive dyskinesia is often resistant to many therapeutic approaches. This review presents the background, evidence, and indications for the use of Valbenazine as a treatment option for this condition…”
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The Laboratory Diagnosis of Hepatitis B Virus by Mel Krajden, Gail McNabb, Martin Petric

“…The availability and extensive use of the HBV vaccine has dramatically reduced the number of incident infections in Canada and worldwide. Effective therapeutic agents have been and continue to be developed to treat chronic infection. …”
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Thymus and activation-regulated chemokine (CCL17) as a clinical biomarker in atopic dermatitis: significance and limitations in the new treatment era by Yoko Kataoka

“…AD treatment has entered a new era with higher therapeutic efficacy. TARC has a different meaning than it did previously, and its significance and limitations are discussed. …”
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Evaluation of Anticoagulation Control among Patients Taking Warfarin in University of Gondar Hospital, Northwest Ethiopia by Zelalem Liyew, Abilo Tadesse, Nebiyu Bekele, Tewodros Tsegaye

“…It has variable intraindividual and interindividual dose response and a narrow therapeutic index. Therefore, it requires frequent and regular international normalized ratio (INR) determination to maintain the INR within the therapeutic range. …”
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Designing hydrogel for application in spinal surgery by Rongpeng Dong, Shuang Zheng, Xueliang Cheng

“…Hydrogel-based treatments have emerged as potentially powerful paradigms for improving therapeutic outcomes and the quality of life of patients. …”
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Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer by Sophia Daum, Lilith Decristoforo, Mira Mousa, Stefan Salcher, Christina Plattner, Baharak Hosseinkhani, Zlatko Trajanoski, Dominik Wolf, Peter Carmeliet, Andreas Pircher

“…This review provides insights into the complex interplay between TECs and the immune system in NSCLC including discussion of potential optimized therapeutic opportunities.…”
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Advances in hydrogel for diagnosis and treatment for Parkinson’s disease by Peining Zhu, Peining Zhu, Peining Zhu, Peining Zhu, Zenghui Zhao, Zenghui Zhao, Zenghui Zhao, Zenghui Zhao, Yufei Gao, Yufei Gao, Yufei Gao, Yufei Gao

“…Hydrogels are conspicuous in many therapeutic applications, including neuron regeneration, neuroprotection, and diagnosis. …”
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Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma by Cecilia Ying Ju Sung, Nikki Pui-yue Lee, Hani El-Nezami

“…As may appear to be a new therapeutic target against tumor-promoting inflammation, strategies such as using probiotics to polarize the response away from may be beneficial to slow down tumor progression. …”
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Influencias recíprocas entre la ginecología y obstetricia europea y la indígena en Uruguay by José Enrique Pons

“…Ethnic medical notions attributed the origin of diseases to supernatural powers, and therapeutic resources were mainly herbal. When Spanish conquerors occupied the territory, they adopted many of the indigenous therapeutic resources for lack of other means, but eventually a slow Europeanization started developing, though native criteria remained for a long while. …”
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