The modification of conventional liposomes for targeted antimicrobial delivery to treat infectious diseases by Nnamdi Ikemefuna Okafor, Omobolanle Ayoyinka Omoteso, Yahya E. Choonara

“…Conventional liposomes have been explored as a delivery system for infectious diseases bioactives to treat infectious diseases to provide an efficient approach to maximize the therapeutic outcomes, drug stability, targetability, to reduce the side-effects of antimicrobials, and enhance vaccine performance where necessary. …”
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Untargeted Metabolite Profiling of Specialty Rice Grains Using Gas Chromatography Mass Spectrometry by Rohit Kambale, M. Raveendran, J. Ramalingam

“…With-ever increasing demand food grains for the increasing population, it has also increased the importance of quality rice with nutritional and therapeutic properties. The quality of rice includes nutritional value, therapeutic properties, and further generation of aroma. …”
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Linum usitatissimum Delivery over Chitosan Nanobiopolymer: Enhanced Effects on Polycystic Ovary Syndrome Condition by Abolfazl Bayrami, Maryam Sojoudi, Shima Rahim Pouran, Aziz Habibi-Yangjeh, Sanaz Sojoudi

“…Considering the negligible therapeutic activity of CHIT-TPP, the enhanced activity of CHIT-FSE compared to only FSE was expounded based on the potent action of chitosan nanoparticles in enhanced stabilization, bioavailability, transport, and permeability of the therapeutically important phytomolecules. …”
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Gingival Mesenchymal Stem/Progenitor Cells: A Unique Tissue Engineering Gem by Karim M. Fawzy El-Sayed, Christof E. Dörfer

“…G-MSCs show remarkable tissue reparative/regenerative potential, noteworthy immunomodulatory properties, and primary experimental therapeutic applications of G-MSCs are very promising, pointing at future biologically based therapeutic techniques, being potentially superior to conventional clinical treatment modalities.…”
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Sclerostin Antibody Therapy for the Treatment of Osteoporosis: Clinical Prospects and Challenges by Claire MacNabb, D. Patton, J. S. Hayes

“…Consequently, additional novel therapeutic targets are increasingly sought. A promising therapeutic candidate is sclerostin, a Wnt pathway antagonist and, as such, a negative regulator of bone formation. …”
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Exploring novel pharmacological trends: Natural compounds in dry eye disease management by Rák Tibor, Csutak Adrienne

“…This article explores various therapeutic approaches, including natural compounds and complementary strategies. …”
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Advances in adjuvant therapy for operable N2 non-small cell lung cancer: a narrative review by Lei Liu, Yilong Mao, Leilei Guo, Chencong Li, Yiqian Wang

“…This article analyzes the current stage of therapeutic advances in operable stage N2 non-small cell lung cancer, and discusses in detail in this article the therapeutic controversy of postoperative adjuvant radiotherapy in pN2 stage non-small cell lung cancer, so as to explore a more reasonable treatment mode for future patients with stage N2 non-small cell lung cancer.…”
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Severe Diltiazem Poisoning Treated with Hyperinsulinaemia-Euglycaemia and Lipid Emulsion by Nadine Monteiro, Joana Silvestre, João Gonçalves-Pereira, Camila Tapadinhas, Vitor Mendes, Pedro Póvoa

“…We present a clinical case of severe diltiazem poisoning and the therapeutic approaches that were used. Case Report. …”
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Targeting Fibrosis: From Molecular Mechanisms to Advanced Therapies by Xingpeng Di, Ya Li, Jingwen Wei, Tianyue Li, Banghua Liao

“…Finally, the current antifibrotic strategies based on therapeutic targets and clinical trials are discussed. …”
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GERD—Barrett—Adenocarcinoma: Do We Have Suitable Prognostic and Predictive Molecular Markers? by Romana Illig, Eckhard Klieser, Tobias Kiesslich, Daniel Neureiter

“…Based on histomorphological findings, detailed screening and therapeutic guidelines have been elaborated, although epidemiological studies could not support the postulated increasing progression rates of GERD to BE and EAC. …”
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Intraoperative Local Administration of Platelet-Rich Plasma (PRP) during Neurolysis Surgery for the Treatment of Digital Nerve Crush Injury by Akira Ikumi, Yuki Hara, Eriko Okano, Sho Kohyama, Norihito Arai, Yu Taniguchi, Hisashi Sugaya, Tomokazu Yoshioka, Akihiro Kanamori, Masashi Yamazaki

“…Platelet-rich plasma (PRP), an autologous product with proven therapeutic effects for musculoskeletal disorders, is a new treatment option for peripheral nerve injury. …”
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Role of silent mutations in KRAS-mutant tumors by Jun Lu, Chao Zhou, Feng Pan, Hongyu Liu, Haohua Jiang, Hua Zhong, Baohui Han, Xiangxiang Pan

“…Understanding these mutations is crucial for comprehensively unraveling KRAS-driven oncogenesis and exploring novel therapeutic avenues. Moreover, investigations into the clinical implications of silent mutations in KRAS-mutant tumors suggest potential diagnostic and therapeutic strategies. …”
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FusOn-pLM: a fusion oncoprotein-specific language model via adjusted rate masking by Sophia Vincoff, Shrey Goel, Kseniia Kholina, Rishab Pulugurta, Pranay Vure, Pranam Chatterjee

“…These proteins are intrinsically disordered and lack druggable pockets, making them highly challenging therapeutic targets for both small molecule-based and structure-based approaches. …”
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Modern modes of chronic hepatitis C treatment by V. T. Ivashkin, M. V. Mayevskaya, M. A. Morozova, Ye. O. Lyusina

“…In particular, the algorithm of therapeutic mode modification according to virologic response to treatment at the specific patient is developed. …”
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Application Strategies of Super-Enhancer RNA in Cardiovascular Diseases by Yi He, Yuwei Cai, Yanyan Cao, Yan Wang, Jing Wang, Hu Ding

“…Cardiovascular diseases (CVDs) are a leading cause of death worldwide, and new therapeutic strategies are urgently needed. In recent years, enhancer RNAs (eRNAs) have gradually attracted attention because they offer new directions for the treatment of CVDs. …”
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Functional Properties of Human-Derived Mesenchymal Stem Cell Spheroids: A Meta-Analysis and Systematic Review by Sarah Ezquerra, Amparo Zuleta, Rodrigo Arancibia, José Estay, Francisco Aulestia, Flavio Carrion

“…Still, further research and clinical studies with controlled and consistent results are needed to see the real therapeutic efficacy of MSC spheroids.…”
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Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research by Foteini Stefania Koumpa, Diamantis Xylas, Maciej Konopka, Dieter Galea, Kirill Veselkov, Anthony Antoniou, Akash Mehta, Reza Mirnezami

“…Acquired data were then divided into hierarchical thematic categories (imaging modalities, translational biomarkers (diagnostic/prognostic/therapeutic), and delivery techniques) and subcategories. …”
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Enhanced Immunogenicity and Affinity with A35R-Fc-Based Chimeric Protein Compared to MPXV A35R Protein by Shimeng Bai, Yanxin Cui, Qibin Liao, Hongyang Yi, Zhonghui Liao, Gengwei Zhang, Fenfang Wu, Hongzhou Lu

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Phytochemistry and pharmacological advances of Ascophyllum nodosum in the management of human diseases: A comprehensive review by Brijesh Singh Chauhan, Yash Pal Singh

“…We used targeted keywords, such as “Ascophyllum nodosum extract,” “pharmacological properties,” “therapeutic applications,” and “bioactive compounds,” to ensure a focused collection of high-quality studies relevant to ANE's health benefits. …”
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Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models by Sheng-Kai Wu, Chia-Lin Tsai, Aisha Mir, Stuart L. Marcus, Kullervo Hynynen

“…Abstract Sonodynamic therapy is an emerging therapeutic approach against brain tumours. However, the treatment scheme and ultrasound parameters have yet to be explored for clinical translation. …”
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