Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications by Zhenglin He, Yishuo Ji, Yutong Yuan, Tianfang Liang, Chenglin Liu, Yiping Jiao, Yimeng Chen, Yiming Yang, Liang Han, Liang Han, Yue Hu, Yue Hu, Xianling Cong, Xianling Cong, Xianling Cong

“…Esophageal cancer (EC) presents substantial therapeutic challenges due to its high mortality rate and the tendency for diagnosis at advanced stages. …”
Get full text

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation by Erin E. Mulvihill, Murray W. Huff

“…Studies in a multitude of models including cell culture, animal and clinical studies demonstrate that citrus-derived flavonoids have therapeutic potential to attenuate dyslipidemia, correct hyperinsulinemia and hyperglycemia, and reduce atherosclerosis. …”
Get full text

Tolerance in Kidney Transplantation: What Is on the B Side? by Laura Carreras-Planella, Francesc E. Borràs, Marcella Franquesa

“…All this hampers the pursuit of an effective Breg induction method for therapeutic purposes. In this review we aim to summarize the studies on human Breg and their implication in kidney transplantation and to further discuss the issues surrounding therapeutic applications of this cell subset.…”
Get full text

Management of Postsurgical Complication in Multiple Implant-Infected Postextraction Sites in the Lower Arch by Frank Mayta-Tovalino, José Rosas, Cesar Mauricio-Vilchez, Silvia Luza, Daniel Alvitez-Temoche, Franco Mauricio

“…Currently, dental implants are a very frequent therapeutic alternative for replacing missing teeth. …”
Get full text

Good-Quality mHealth Apps for Endometriosis Care: Systematic Search by Diksha Sirohi, Cecilia HM Ng, Niranjan Bidargaddi, Helen Slater, Melissa Parker, M Louise Hull, Rebecca O'Hara

“…Few eHealth websites scored well on therapeutic persuasiveness (6/19, 31.6%), therapeutic alliance (9/19, 47.4%), and general subjective evaluation (6/19, 31.6%). …”
Get full text

Formulation of Hydrogel Beads to Improve the Bioaccessibility of Bioactive Compounds from Goldenberry and Purple Passion Fruit and Evaluation of Their Antiproliferative Effects on... by Ana María Naranjo-Durán, Diego Miedes, Juan Manuel Patiño-Osorio, Antonio Cilla, Amparo Alegría, Catalina Marín-Echeverri, Julián Quintero-Quiroz, Gelmy Luz Ciro-Gómez

Get full text

Daidzein improves muscle atrophy caused by lovastatin by regulating the AMPK/FOXO3a axis by Keke Wang, Hao Zeng, Hua Yang

“…Daidzein, an isoflavone derived from soybeans and many Chinese medicines, shows therapeutic potential in treating muscle-related diseases and metabolic disorders. …”
Get full text

Melasma management: Unveiling recent breakthroughs through literature analysis by Darshan Kumar R, Richa Sood, Prashant Tiwari

“…Over the years, various therapeutic approaches, including topical agents, chemical peels, laser treatments, and oral medications, have been explored. …”
Get full text

Protective effects of small RNAs encapsulated in Artemisia Capillaris-derived exosomes against non-alcoholic fatty liver disease by Min Xu, Longjun Ma, Hongwei Liang, Wei Tang, Shouyong Gu

“…IntroductionArtemisia capillaris, a traditional medicinal plant, is renowned for its therapeutic properties, including the promotion of anti-inflammatory and bile secretion. …”
Get full text

High incidence of radiation-induced brain necrosis in the periventricular deep white matter: stereotactic radiotherapy for brain metastases using volumetric modulated arc therapy by Takayuki Ohguri, Hirohide Itamura, Subaru Tani, Eiji Shiba, Junkoh Yamamoto

Get full text

Utilizing the subtractive proteomics approach to design ensemble vaccine against Candida lusitaniae for immune response stimulation; a bioinformatics study. by Habiba Naz, Rimsha Timotheous, Muhammad Farhan Sarwar, Tariq Nadeem, Mudassar Fareed Awan, Sajed Ali, Sophia Awais, Irfan Ahmed

“…Vaccines have always been one of the promising therapeutic sources against many pathogens including infectious fungi. …”
Get full text

Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer? by Tryambak Pratap Srivastava, Ruby Dhar, Subhradip Karmakar

“…The increasing global burden of BrCa, particularly in low- and middle-income countries, underscores the urgent need for more effective therapeutic strategies. The androgen receptor (AR), expressed in a substantial proportion of breast cancer cases, has emerged as a potential biomarker and therapeutic target. …”
Get full text

Development of a New Malnutrition Screening Tool for Patients: Human Key Tool of Nutrition by Kotono Oishi, MSc, Arisa Inoue-Hamano, PhD, Yasuhiro Hamada, MD,PhD

Get full text

Nonpharmacological Interventions for Protection of Myocardial Ischemia-reperfusion Injury among Patient with ST Elevation Myocardial Infarction: A Brief Review by Mandeep Kumar Jangra, Mehroz Ahmed Mirza, Manu Goyal

“…Population, Intervention, Comparator, Outcomes, Study design format was used to assess the eligibility of articles where population was ST elevated MI; Intervention was any nonpharmacological interventions such as ischemic postconditioning, therapeutic hypothermia, low level laser therapy (LLLT), remote ischemic conditioning (RIC), and therapeutic hyperoxemia; Comparator can be placebo/sham or control groups, Outcomes were infarct size and cardiac biomarkers and study design can be randomized clinical trials, pre–post experimental studies, etc. …”
Get full text

New T-lymphocyte subpopulations and their characteristics: Challenges to the classical division of lymphocyte function by Filip Lewandowski, Paulina Niedźwiedzka-Rystwej

“…These findings expand our understanding of T-lymphocyte biology and suggest targets for more effective therapeutic interventions. Further research is essential to fully elucidate the clinical relevance and therapeutic potential of these T-lymphocyte subpopulations, paving the way for personalized and targeted immune-based treatments.…”
Get full text

Strains, Mechanism, and Perspective: Salmonella-Based Cancer Therapy by Cheng-Zhi Wang, Robert A. Kazmierczak, Abraham Eisenstark

“…In this review, we focus on three tumor-therapeutic Salmonella models, the most intensively studied bacterial genus in this field. …”
Get full text

Spinal Cord Injury and Bladder Dysfunction: New Ideas about an Old Problem by Célia Duarte Cruz, Francisco Cruz

“…As such, a better understanding of NDO has generated new opportunities to investigate novel therapeutic approaches for NDO.In the present paper, we aim to update recent data concerning SCI-induced LUT dysfunction and therapeutic approaches commonly used to deal with NDO. …”
Get full text

Measuring Brain Tumor Growth: Combined Bioluminescence Imaging–Magnetic Resonance Imaging Strategy by Sarah C. Jost, Lynne Collins, Sarah Travers, David Piwnica-Worms, Joel R. Garbow

“…Small-animal tumor models are essential for developing translational therapeutic strategies in oncology research, with imaging having an increasingly important role. …”
Get full text

Targeting capabilities of engineered extracellular vesicles for the treatment of neurological diseases by Xinyu Yang, Xiangyu Gao, Xiaofan Jiang, Kangyi Yue, Peng Luo

“…Recent advances in research on extracellular vesicles have significantly enhanced their potential as therapeutic agents for neurological diseases. Owing to their therapeutic properties and ability to cross the blood–brain barrier, extracellular vesicles are recognized as promising drug delivery vehicles for various neurological conditions, including ischemic stroke, traumatic brain injury, neurodegenerative diseases, glioma, and psychosis. …”
Get full text

Successful Treatment of Genitofemoral Neuralgia Using Ultrasound Guided Injection: A Case Report and Short Review of Literature by Harsha Shanthanna

“…As a therapeutic procedure, genitofemoral nerve block is done in patients with genitofemoral neuralgia. …”
Get full text