Clinical Practice Guideline for the Care of Elderly Patients Hospitalized with Delirium by Ángel Julio Romero Carbrera, Leocadia Amores Hernández, Ernesto Alonso Cabrera, Francisco Olascoaga Pérez, Eduardo Fernández Casteleiro

“…It is characterized by an acute disorder of consciousness and alterations in behavior, posing a diagnostic and therapeutic challenge for the doctors that look after geriatric patients. …”
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Severe late onset capillary leak syndrome post allo-HSCT successfully treated by bevacizumab: a case report by Song Xue, Jiaqi Chen, Yuzhu Shi, Lina Zhang, Man Chen, Huipeng Sun, Xingyu Cao, Fang Wu

“…The prognosis for CLS remains considerably constrained. A targeted therapeutic approach targeting vascular endothelial growth factor (VEGF) offers a novel strategy for the management of CLS.…”
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REVIEW by Claudia-Ştefania Bala

“…Iron, ferroptosis and association with tumoral evolution and potential therapeutic impact Decision making in Merkel cell carcinoma – surgical oncologist point of view Cardiac toxicity of checkpoint inhibitors (CPI) used in cancer immunotherapy Immune-mediated complications of monoclonal antibodies used in onco-hematology …”
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Traumatic Page Kidney Induced Hypertension in Critical Care: Immediately Resolved or Long-Term Resistant Problem by E. Brotfain, L. Koyfman, A. Frenkel, A. Smolikov, A. Zlotnik, M. Klein

“…We discuss different therapeutical opportunities to extremely elevated systemic blood pressure resistant to traditional drug therapy.…”
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Direct and Indirect Drug Design Approaches for the Development of Novel Tricyclic Antipsychotics: Potential 5-HT2A Antagonist by Mahantesh Namdev Jadhav, Ganesh Rajendra Kokil, Shilpa Sudhakar Harak, Sanjay Baburao Wagh

“…Schizophrenia is a mental disorder manifested largely by disintegration of thought processes and emotional responsiveness. Given the therapeutic and toxic limitations of clinically available drugs, it is clear that there is still a need for the development of new generation antipsychotic agents with an improved clinical profile. …”
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Unraveling complexity and leveraging opportunities in uncommon breast cancer subtypes by Fresia Pareja, Rohit Bhargava, Virginia F. Borges, Edi Brogi, Rita Canas Marques, Fatima Cardoso, Christine Desmedt, Malini Harigopal, Sunil R. Lakhani, Adrian Lee, Jose Pablo Leone, Hannah Linden, Christopher J. Lord, Caterina Marchio, Sofia D. Merajver, Emad Rakha, Jorge S. Reis-Filho, Andrea Richardson, Elinor Sawyer, Pepper Schedin, Christopher J. Schwartz, Andrew Tutt, Naoto T. Ueno, Anne Vincent-Salomon, Britta Weigelt, Y. Hannah Wen, Stuart J. Schnitt, Steffi Oesterreich

“…Abstract Special histologic subtypes of breast cancer (BC) exhibit unique phenotypes and molecular profiles with diagnostic and therapeutic implications, often differing in behavior and clinical trajectory from common BC forms. …”
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Phytochemical and Antimicrobial Studies of Medicinal Plant Costus Speciosus (Koen.) by Aparna Saraf

“…The present paper deals with the phytochemical and antimicrobial screening of therapeutic importance from Costus speciosus (Koen.), an important medicinal plant. …”
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Extracellular vesicle-mediated approaches for the diagnosis and therapy of MASLD: current advances and future prospective by Swasthika Gurjar, Ramanarayana Bhat A, Raghavendra Upadhya, Revathi P. Shenoy

“…This review also explores the therapeutic potential of EVs as key components in the future management of liver disease. …”
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Exploring a New Cueing Device in People Who Experience Freezing of Gait: Acceptance of a Study Design by Agnes Wilhelm, Tanja Riedl, Christian Paumann, Jessie Janssen

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Homeopathic Preparations to Control the Rosy Apple Aphid (Dysaphis plantaginea Pass.) by Eric Wyss, Lucius Tamm, Joachim Siebenwirth, Stephan Baumgartner

“…Six experiments were determined to assess the effects of a strict therapeutic treatment; two experiments were designed to determine the effects of a combined preventative and therapeutic treatment. …”
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Targeting Invasion: The Role of MMP-2 and MMP-9 Inhibition in Colorectal Cancer Therapy by Alireza Shoari, Arghavan Ashja Ardalan, Alexandra M. Dimesa, Mathew A. Coban

“…Colorectal cancer (CRC) remains one of the most prevalent and lethal cancers worldwide, prompting ongoing research into innovative therapeutic strategies. This review aims to systematically evaluate the role of gelatinases, specifically MMP-2 and MMP-9, as therapeutic targets in CRC, providing a critical analysis of their potential to improve patient outcomes. …”
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Combined Treatment with Zinc Aspartate and Intravenous Immunoglobulins (IVIGs) Ameliorates Experimental Autoimmune Encephalomyelitis (EAE) by Diana Straubel, Anja Thielitz, Annegret Reinhold, Kurt Grüngreiff, Dirk Reinhold

“…In contrast, IVIG given in a therapeutic manner did not influence the course of EAE. …”
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Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants by Susana Martiñón, Angel Cisneros, Sergio Villicaña, Ricardo Hernández-Miramontes, Edgar Mixcoha, Psyché Calderón-Vargas

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Hyssopus cuspidatus volatile oil: a potential treatment for steroid-resistant asthma via inhibition of neutrophil extracellular traps by Xu Wang, Hui-Ming Peng, Meng-Ru Zhang, Jing-Jing Li, Chuan-Peng Zhao, Ya-Li Zhang, Si-Yu Wang, Si-Ying Zhu, Jian-Kang Lu, Hai-Long Yin, Qiang Yin, Jin-Bo Fang

“…Conclusion These findings suggest that HVO is a promising therapeutic candidate for neutrophil-dominant SRA by targeting NETs formation.…”
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Exosome-loaded tannic acid–thioctic acid hydrogel enhances wound healing in coagulation disorders by Yuesheng Tu, Weixin Zheng, Zichu Ding, Jie Xiang, Qinfeng Yang, Yuchen Liu, Jue Cao, Yuling Shen, Zinan Tang, Shen Lin, Lei Fan, Yaowen Xu, Bin Chen

“…This study explored a novel tannic acid-thioctic acid (TATA) hydrogel, enriched with exosomes derived from bone marrow mesenchymal stem cells, as a therapeutic strategy for enhancing skin wound healing in a hemophilia model. …”
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A select inhibitor of MORC2 encapsulated by chimeric membranecoated DNA nanocage target alleviation TNBC progression by Xiaohan Su, Yunbo Luo, Yali Wang, Peng Qu, Jun Liu, Shiqi Han, Cui Ma, Shishan Deng, Qi Liang, Xiaowei Qi, Panke Cheng, Lingmi Hou

“…Triple-negative breast cancer (TNBC) is the most malignant type of breast cancer and lacks effective targeted therapeutic drugs, resulting in a high recurrence rate and worse outcome. …”
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Toxicological Review of Anticancer Plants Used in Traditional Medicine in Morocco by Soufiane Drioua, Abha Cherkani-Hassani, Otman El-Guourrami, Mouna Ameggouz, Ahmed Zahidi, Abdelhakim Bouyahaya, Sayyed Ibrahim Shah, Yaser Mohammed Al-Worafi, Long Chiau Ming, Hanane Benzaied, Anass Doukkali

“…Further research may be able to explore and discover the potential therapeutic effects of these plants' bioactive molecules with antioxidant and anticancer properties. …”
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Virtual Screening as a Technique for PPAR Modulator Discovery by Stephanie N. Lewis, Josep Bassaganya-Riera, David R. Bevan

“…Virtual screening (VS) is a discovery technique to identify novel compounds with therapeutic and preventive efficacy against disease. …”
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Targeting ion homeostasis in metabolic diseases: Molecular mechanisms and targeted therapies by Yanjiao Zhang, Kaile Ma, Xinyi Fang, Yuxin Zhang, Runyu Miao, Huifang Guan, Jiaxing Tian

“…In summary, targeting ion homeostasis provides a new perspective and potential therapeutic approach for the treatment of metabolic diseases.…”
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Orchestrating cancer therapy: Recent advances in nanoplatforms harmonize immunotherapy with multifaceted treatments by Rongwei Xu, Pei Lin, Jiarong Zheng, Yunfan Lin, Zizhao Mai, Ye Lu, Xu Chen, Zihao Zhou, Li Cui, Xinyuan Zhao

“…Nanoplatforms enable precise delivery and controlled release of therapeutic agents, which enhances treatment specificity and reduces systemic toxicity. …”
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