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2561
Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys (Saimiri sciureus)
Published 2024-01-01“…Nonhuman primates are an important experimental model for the development of targeted biological therapeutics because of their immunological closeness to humans. …”
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2562
A partial differential equation model of metastasized prostatic cancer
Published 2013-03-01“…Finally, numerical simulations of a tumor growing in 2-dimensions with radial symmetry are carried in order to evaluate the therapeutic potential of different treatment strategies. …”
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2563
Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke
Published 2024-12-01“…This literature review encompasses pertinent information on the impact and versatility of nanoparticle therapeutics when treating neurotrauma, stroke, and SAH. …”
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Pharmacological ascorbate combined with rucosopasem selectively radio-chemo-sensitizes NSCLC via generation of H2O2
Published 2025-03-01“…Differences in cancer and normal cell oxidative metabolism provide a unique therapeutic opportunity for developing combined modality approaches with redox-active small molecules as radio-chemosensitizers that are well-tolerated by normal tissues. …”
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T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration
Published 2025-03-01“…The review also summarizes the specific roles of different T cell subsets, including CD4+ T cells, CD8+ T cells, regulatory T cells, T helper 17 cells, and γδ T cells in modulating fracture healing. The current therapeutics targeting T cell immunity to enhance fracture healing have also been reviewed, aiming to provide insights from a translational standpoint. …”
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2571
Aquaporins in oral health and disease: A narrative review
Published 2023-07-01“…The present review provides an overview of the pathophysiology involving AQPs that can help scientists to design treatment therapeutics for various disease conditions.…”
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2572
Dynamic Roles of RNA and RNA Epigenetics in HTLV-1 Biology
Published 2025-01-01“…This review will highlight the dynamic roles of known RNA and post-transcriptional RNA epigenetic modifications within HTLV-1 biology, including viral <i>hbz</i>, long noncoding RNAs, microRNAs (miRNAs), transfer RNAs (tRNAs), R-loops, N6-methyladenosine (m<sup>6</sup>A) modifications, and RNA-based therapeutics and vaccines.…”
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2573
Regulation of Hippo-YAP1/TAZ pathway in metabolic dysfunction-associated steatotic liver disease
Published 2025-01-01“…In this review, we highlight the regulation and molecular mechanism of the Hippo–YAP1/TAZ pathway in MASLD and summarize potential therapeutic strategies for MASLD by regulating Hippo–YAP1/TAZ pathway.…”
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2574
Motion – Helicobacter pylori Causes or Worsens GERD: Arguments against the Motion
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2575
Toll-Like Receptors: Role in Dermatological Disease
Published 2010-01-01“…In this paper, we will describe the association between TLRs and various skin pathologies and discuss proposed TLR therapeutics.…”
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2576
Nanosystems for modulation of immune responses in periodontal therapy: a mini-review
Published 2025-01-01“…Based on this premise, many therapeutic modalities have been investigated or attempted to resolve this inflammatory disease. …”
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2577
Targeting the Endocannabinoid System for Prevention or Treatment of Chemotherapy-Induced Neuropathic Pain: Studies in Animal Models
Published 2018-01-01“…The studies analysed suggest that targeting the endocannabinoid system for prevention and treatment of CINP is a plausible therapeutic option. Almost 90% of the studies on animal models of CINP analysed utilised male rodents. …”
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2578
Retinal Surface Macrophage Changes in Thyroid Eye Disease before and after Treatment with Teprotumumab
Published 2022-01-01“…We examined the variation of parafoveal surface macrophages in a thyroid eye disease (TED) patient before and after treatment with teprotumumab (Tepezza, Horizon therapeutics). Pre- and posttreatment parafoveal surface macrophages were imaged using clinical en face OCT, and their density was assessed using a novel cell density mapping technique. …”
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2579
The cytokine network of acute HIV infection: a promising target for vaccines and therapy to reduce viral set-point?
Published 2011-08-01“…We also discuss unresolved questions that are essential for our understanding of the role of acute infection cytokines in HIV infection and that, if answered, may suggest novel therapeutic and vaccine strategies to control the worldwide HIV pandemic.…”
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2580
CCL24 and Fibrosis: A Narrative Review of Existing Evidence and Mechanisms
Published 2025-01-01“…We focus on the preclinical and clinical evidence supporting the therapeutic potential of blocking CCL24 in diseases that involve excessive inflammation and fibrosis.…”
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