Showing 2,561 - 2,580 results of 12,750 for search '"therapeutics"', query time: 0.11s Refine Results
  1. 2561

    Identification of Specific Cell Surface Markers on Immune Cells of Squirrel Monkeys (Saimiri sciureus) by Bharti P. Nehete, Ashley DeLise, Pramod N. Nehete

    Published 2024-01-01
    “…Nonhuman primates are an important experimental model for the development of targeted biological therapeutics because of their immunological closeness to humans. …”
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    Article
  2. 2562

    A partial differential equation model of metastasized prostatic cancer by Avner Friedman, Harsh Vardhan Jain

    Published 2013-03-01
    “…Finally, numerical simulations of a tumor growing in 2-dimensions with radial symmetry are carried in order to evaluate the therapeutic potential of different treatment strategies. …”
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    Article
  3. 2563

    Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke by Grace Hey, Ilyas Mehkri, Yusuf Mehkri, Hasan Maqbool, Mubariz Tahirkheli, Samuel Woodford, Brandon Lucke-Wold

    Published 2024-12-01
    “…This literature review encompasses pertinent information on the impact and versatility of nanoparticle therapeutics when treating neurotrauma, stroke, and SAH. …”
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    Article
  4. 2564
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  6. 2566

    Pharmacological ascorbate combined with rucosopasem selectively radio-chemo-sensitizes NSCLC via generation of H2O2 by C.F. Pulliam, M.A. Fath, S. Sho, S.T. Johnson, B.A. Wagner, M. Singhania, A.L. Kalen, K. Bayanbold, S.R. Solst, B.G. Allen, B.N. George, J.M. Caster, G.R. Buettner, D.P. Riley, J.L. Keene, R.A. Beardsley, D.R. Spitz

    Published 2025-03-01
    “…Differences in cancer and normal cell oxidative metabolism provide a unique therapeutic opportunity for developing combined modality approaches with redox-active small molecules as radio-chemosensitizers that are well-tolerated by normal tissues. …”
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    Article
  7. 2567
  8. 2568
  9. 2569

    T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration by Haixing Wang, Yashi Li, Haoxin Li, Xu Yan, Zhaowei Jiang, Lu Feng, Wenhui Hu, Yinuo Fan, Sien Lin, Gang Li

    Published 2025-03-01
    “…The review also summarizes the specific roles of different T cell subsets, including CD4+ T cells, CD8+ T cells, regulatory T cells, T helper 17 cells, and γδ T cells in modulating fracture healing. The current therapeutics targeting T cell immunity to enhance fracture healing have also been reviewed, aiming to provide insights from a translational standpoint. …”
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    Article
  10. 2570
  11. 2571

    Aquaporins in oral health and disease: A narrative review by Shailja Chatterjee

    Published 2023-07-01
    “…The present review provides an overview of the pathophysiology involving AQPs that can help scientists to design treatment therapeutics for various disease conditions.…”
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    Article
  12. 2572

    Dynamic Roles of RNA and RNA Epigenetics in HTLV-1 Biology by Emily M. King, Amanda R. Panfil

    Published 2025-01-01
    “…This review will highlight the dynamic roles of known RNA and post-transcriptional RNA epigenetic modifications within HTLV-1 biology, including viral <i>hbz</i>, long noncoding RNAs, microRNAs (miRNAs), transfer RNAs (tRNAs), R-loops, N6-methyladenosine (m<sup>6</sup>A) modifications, and RNA-based therapeutics and vaccines.…”
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    Article
  13. 2573

    Regulation of Hippo-YAP1/TAZ pathway in metabolic dysfunction-associated steatotic liver disease by Wei Xuan, Dandan Song, Jianghua Hou, Xiuping Meng

    Published 2025-01-01
    “…In this review, we highlight the regulation and molecular mechanism of the Hippo–YAP1/TAZ pathway in MASLD and summarize potential therapeutic strategies for MASLD by regulating Hippo–YAP1/TAZ pathway.…”
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    Article
  14. 2574
  15. 2575

    Toll-Like Receptors: Role in Dermatological Disease by Aswin Hari, Tracy L. Flach, Yan Shi, P. Régine Mydlarski

    Published 2010-01-01
    “…In this paper, we will describe the association between TLRs and various skin pathologies and discuss proposed TLR therapeutics.…”
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    Article
  16. 2576

    Nanosystems for modulation of immune responses in periodontal therapy: a mini-review by Anirudh B. Acharya, Usha Hegde, Swetha Acharya

    Published 2025-01-01
    “…Based on this premise, many therapeutic modalities have been investigated or attempted to resolve this inflammatory disease. …”
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    Article
  17. 2577

    Targeting the Endocannabinoid System for Prevention or Treatment of Chemotherapy-Induced Neuropathic Pain: Studies in Animal Models by Willias Masocha

    Published 2018-01-01
    “…The studies analysed suggest that targeting the endocannabinoid system for prevention and treatment of CINP is a plausible therapeutic option. Almost 90% of the studies on animal models of CINP analysed utilised male rodents. …”
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    Article
  18. 2578

    Retinal Surface Macrophage Changes in Thyroid Eye Disease before and after Treatment with Teprotumumab by Oscar Otero-Marquez, Mona Fayad, Alexander Pinhas, Toco Y. P. Chui, Richard B. Rosen, Harsha S. Reddy

    Published 2022-01-01
    “…We examined the variation of parafoveal surface macrophages in a thyroid eye disease (TED) patient before and after treatment with teprotumumab (Tepezza, Horizon therapeutics). Pre- and posttreatment parafoveal surface macrophages were imaged using clinical en face OCT, and their density was assessed using a novel cell density mapping technique. …”
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    Article
  19. 2579

    The cytokine network of acute HIV infection: a promising target for vaccines and therapy to reduce viral set-point? by Peter D Katsikis, Yvonne M Mueller, François Villinger

    Published 2011-08-01
    “…We also discuss unresolved questions that are essential for our understanding of the role of acute infection cytokines in HIV infection and that, if answered, may suggest novel therapeutic and vaccine strategies to control the worldwide HIV pandemic.…”
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    Article
  20. 2580

    CCL24 and Fibrosis: A Narrative Review of Existing Evidence and Mechanisms by Raanan Greenman, Chris J. Weston

    Published 2025-01-01
    “…We focus on the preclinical and clinical evidence supporting the therapeutic potential of blocking CCL24 in diseases that involve excessive inflammation and fibrosis.…”
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    Article