LongReadSum: A fast and flexible quality control and signal summarization tool for long-read sequencing data by Jonathan Elliot Perdomo, Mian Umair Ahsan, Qian Liu, Li Fang, Kai Wang

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Chiral clues to lipid identity by Ujjalkumar S. Das, Garret A. FitzGerald

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Liposomal Formulation of Hydroxychloroquine Can Inhibit Autophagy In Vivo by Wieslawa H. Dragowska, Jagbir Singh, Mohamed Wehbe, Malathi Anantha, Katarina Edwards, Sharon M. Gorski, Marcel B. Bally, Ada W. Y. Leung

“…<b>Background/Objectives:</b> Preclinical studies have shown that the anti-malarial drug hydroxychloroquine (HCQ) improves the anti-cancer effects of various therapeutic agents by impairing autophagy. These findings are difficult to translate in vivo as reaching an effective HCQ concentration at the tumor site for extended times is challenging. …”
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PPARs and Metabolic Syndrome by Lihong Chen, Zhanjun Jia, Guangrui Yang

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Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature by Lampros Samartzis, Paraskevi Savvari, Sofoklis Kontogiannis, Stavros Dimopoulos

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Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy by Mari Aikio, Hana M. Odeh, Heike J. Wobst, Bo Lim Lee, Úna Chan, Jocelyn C. Mauna, Korrie L. Mack, Bradley Class, Thomas A. Ollerhead, Alice F. Ford, Edward M. Barbieri, Ryan R. Cupo, Lauren E. Drake, Joshua L. Smalley, Yuan-Ta Lin, Stephanie Lam, Reuben Thomas, Nicholas Castello, Ashmita Baral, Jenna N. Beyer, Mohd A. Najar, John Dunlop, Aaron D. Gitler, Ashkan Javaherian, Julia A. Kaye, George M. Burslem, Dean G. Brown, Christopher J. Donnelly, Steven Finkbeiner, Stephen J. Moss, Nicholas J. Brandon, James Shorter

“…Thus, strategies to reduce p38α-mediated TDP-43 phosphorylation and promote PRMT1-mediated R293 methylation could have therapeutic utility for ALS and related TDP-43 proteinopathies.…”
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Stroke Outcome and Determinants among Patients with and without Diabetes in a Tertiary Hospital in Ghana by Josephine Akpalu, Alfred E. Yawson, Foster Osei-Poku, Yacoba Atiase, Ernest Yorke, Patrick Adjei, Kodwo Nkromah, Albert Akpalu

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Characteristics and Management of Uncontrolled Gout Prior to Pegloticase Therapy: A 2-year Claims Analysis by Robert J. Morlock, Deepan Dalal, Victoria Divino, Mitchell DeKoven, Stephanie D. Taylor, Atsuko Powers, Naina Barretto, Robert J. Holt, Brian LaMoreaux

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Cytopenia among CML Patients on Imatinib in Kenya: Types, Grades, and Time Course by Angela McLigeyo, Jamilla Rajab, Mohammed Ezzi, Peter Oyiro, Yatich Bett, Andrew Odhiambo, Matilda Ong’ondi, Sitna Mwanzi, Mercy Gatua, NAOthieno- Abinya

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Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers by Pablo E. Pergola, Melanie S. Joy, Armando Garsd, Steve J. Hasal, Atul Khare, Guru Reddy, Pramod Gupta, William F. Finn

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A lectin produced by a Streptomyces species targets mammalian pancreatic acinar cells in mice and humans by Janine C. Quijano, Honoka Natsuyama, Alonso Tapia, Karine Bagramyan, Jose A. Ortiz, Jacob Mares, Markus Kalkum, Yoko Fujita-Yamaguchi, Hsun Teresa Ku

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Rockwood Clinical Frailty Scale as a predictor of adverse outcomes among older adults undergoing aortic valve replacement: a protocol for a systematic review by Rose Galvin, Ahmed Gabr, Catherine Peters, Margaret O'Connor, Aoife Leahy, Elaine Shanahan, Tadhg Prendiville, Laura Quinlan, Anastasia Saleh, Ivan Casserly

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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease by D. Luke Fischer, Marissa Menard, Omar Z. Abdelaziz, Nicholas M. Kanaan, Virginia G. Cobbs, Richard E. Kennedy, Geidy E. Serrano, Thomas G. Beach, Laura A. Volpicelli-Daley

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Identification and Potential Clinical Utility of Common Genetic Variants in Gestational Diabetes among Chinese Pregnant Women by Claudia Ha-ting Tam, Ying Wang, Chi Chiu Wang, Lai Yuk Yuen, Cadmon King-poo Lim, Junhong Leng, Ling Wu, Alex Chi-wai Ng, Yong Hou, Kit Ying Tsoi, Hui Wang, Risa Ozaki, Albert Martin Li, Qingqing Wang, Juliana Chung-ngor Chan, Yan Chou Ye, Wing Hung Tam, Xilin Yang, Ronald Ching-wan Ma

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Systemically circulating 17β-estradiol enhances the neuroprotective effect of the smoking cessation drug cytisine in female parkinsonian mice by Sara M. Zarate, Roger C. Garcia, Gauri Pandey, Rahul Srinivasan

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Reversible Cortical Blindness as a Prominent Manifestation of Cerebral Embolism due to Infective Endocarditis by Georgios P. Kranidiotis, Alexandra N. Gougoutsi, Theodoros A. Retsas, Maria I. Anastasiou-Nana

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Intrinsic PD‐L1 Degradation Induced by a Novel Self‐Assembling Hexapeptide for Enhanced Cancer Immunotherapy by Hongxia Zhang, Ming Ji, Yamei Wang, Mengmeng Jiang, Zongyu Lv, Gongyu Li, Lulu Wang, Zhen Zheng

“…Loading the hydrogel with mitoxantrone (MTX) and metformin (MET) further enhances the therapeutic effect by combining chemotherapy with PD‐L1 downregulation. …”
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Differences and analogies in thyroid cancer discovered incidentally or by thyroid-related screening: a multicenter study by Laura Croce, Rosaria Maddalena Ruggeri, Camilla Virili, Carlo Cappelli, Marsida Teliti, Pietro Costa, Spyridon Chytiris, Antonio Nicocia, Francesca Coperchini, Maria Flavia Bagaglini, Flavia Magri, Alfredo Campennì, Mario Rotondi

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Diffuse Large B-Cell Lymphoma with Calf Muscle Localization by Laura Bourdeanu, Rashmi Menon, George Somlo

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Gene Expression is Selectively Affected along the Epididymis after Orchidectomy by Nadine N. Ezer, Bernard Robaire

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