Evaluating knowledge gains from structured sexual and reproductive health education among in-school adolescents in Southeast Nigeria by Chibuike Agu, Chinyere Ojiugo Mbachu, Ifunanya Clara Agu, Godstime Eigbiremolen, Ugenyi Iloabachie, Ozioma Nwankpa, Obinna Onwujekwe

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A Rare Case of Glioblastoma Multiforme with Osseous Metastases by Rubens Barros Costa, Ricardo Costa, Jason Kaplan, Marcelo Rocha Cruz, Hiral Shah, Maria Matsangou, Benedito Carneiro

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Impact of Tacrolimus, Sirolimus, Age, and Body Mass Index on the Occurrence of Skin Cancer and Islet Dysfunction After Transplantation by Christopher Orr, Jeannette Stratton, Mohamed El-Shahawy, Elena Forouhar, Alice Peng, Gagandeep Singh, Keiko Omori, Meirigeng Qi, Fouad Kandeel

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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report by Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa Matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto

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Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus by Maria Sultan, Maria Razzaq, Joohyun Lee, Shreyasi Das, Shrute Kannappan, Vinod Kumar Subramani, Wanki Yoo, Truc Kim, Hye-Ra Lee, Akhilesh K. Chaurasia, Kyeong Kyu Kim

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Reply to: Oligoclonality of TRBC1 and TRBC2 in T cell lymphomas as mechanism of primary resistance to TRBC-directed CAR T cell therapies by Mathieu Ferrari, Farhaan Parekh, Paul Maciocia, Pedro Horna, Simon Thomas, Andrew K. Sewell, Martin Pule

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Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory... by James Olukayode Oni, Divine Oluwaferanmi Oyenekan, Yetunde Olamide Olayemi, Osarugue Christabel Irabor, Precious Ogbuji, McCarthy Oritseweyinmi Tova, Paul Ademola Adeleke, Gbemisayo Adetomiwa Abbas, Solomon Umukoro

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Phenylbutyric Acid Modulates Apoptosis and ER Stress‐Related Gene Expression in Glycogen Storage Disease Type Ib In Vitro Model by Marina Parezanovic, Nina Stevanovic, Marina Andjelkovic, Milena Ugrin, Sonja Pavlovic, Maja Stojiljkovic, Anita Skakic

“…Conclusion This cost‐effective in vitro model screens the therapeutic potential of SMs affecting ER stress and apoptosis in G6PT‐deficient kidney cells, offering a first‐line screening assay for promising compounds. 4‐PBA's potential repurposing for GSD Ib patients opens new research directions.…”
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Muscarinic acetylcholine receptor 3 localized to primary endothelial cilia regulates blood pressure and cognition by Hannah C. Saternos, Kathleen V. Forero, Mahmood A. Meqdad, Raghad Buqaileh, Clare L. Sunderman, Gillian Gallagher, William S. Messer, Ashraf M. Mohieldin, Claudio A. Mucci, Sanjana Kumariya, Islam A. Osman, James P. Burkett, Wissam A. AbouAlaiwi

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CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production by Emily E. O’Driscoll, Sakshi Arora, Jonathan F. Lang, Beverly L. Davidson, Ophir Shalem

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Application of Ultrasound to Selectively Localize Nanodroplets for Targeted Imaging and Therapy by Paul A. Dayton, Shukui Zhao, Susannah H. Bloch, Pat Schumann, Kim Penrose, Terry O. Matsunaga, Reena Zutshi, Alexander Doinikov, Katherine W. Ferrara

“…Additionally, we demonstrate the feasibility of US-enhanced particle internalization and therapeutic delivery.…”
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Clinical characteristics and outcomes of incident haemodialysis-treated adult patients in Kenya: Brief paper about basic research by Samuel K. Kabinga, Seth O. McLigeyo, Anson K. Mwango, Davies O. Otieno, Evans A. Onyango, Priscah D. Chemutai, Duncan G. Irungu, John N. Ndungu

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Genome analysis uncovers an inverse correlation between alterations in P21‐activated kinases and patient survival across multiple cancer types by Jessie M. Vo, Linh M. La, Ananda V. Anderson, Abdulaziz H. Alanazi, Payaningal R. Somanath

“…Our findings underscore the importance of PAK isoforms as potential biomarkers and therapeutic targets, particularly in metastatic cancers. …”
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Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging by Karienn A. de Souza, Morgan Jackson, Justin Chen, Jocelin Reyes, Judy Muayad, Emma Tran, William Jackson, M. Karen Newell-Rogers, David J. Earnest

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Preventive but Not Curative Efficacy of Celecoxib on Bladder Carcinogenesis in a Rat Model by José Sereno, Belmiro Parada, Flávio Reis, Fernanda X. Cunha, Edite Teixeira-Lemos, Patrícia Garrido, Rui Pinto, Petronila Rocha-Pereira, Paula Neto, José Ruivo, Paulo Rodrigues-Santos, Sara Nunes, Alfredo Mota, Arnaldo Figueiredo, Frederico Teixeira

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Pegloticase and Methotrexate Cotherapy in Patients With Uncontrolled Gout With Prior Pegloticase Monotherapy Failure: Findings of an Open‐Label Trial by Orrin M. Troum, John K. Botson, Katie Obermeyer, Bo Chao, Yang Song, Jennifer Zarzoso, Kjerstina Gutierrez, Supra Verma, Lissa Padnick‐Silver, Brian LaMoreaux

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Lithium and Valproate Levels Do Not Correlate with Ketamine’s Antidepressant Efficacy in Treatment-Resistant Bipolar Depression by Annie J. Xu, Mark J. Niciu, Nancy B. Lundin, David A. Luckenbaugh, Dawn F. Ionescu, Erica M. Richards, Jennifer L. Vande Voort, Elizabeth D. Ballard, Nancy E. Brutsche, Rodrigo Machado-Vieira, Carlos A. Zarate

“…We hypothesized that ketamine’s antidepressant effects would be improved by therapeutic doses of lithium versus valproate and that serum lithium levels would positively correlate with ketamine’s antidepressant efficacy. …”
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Shorter Digestion Times of Donor Islets Is Associated With Better Islet Graft Function After Islet Transplantation by Chia-Hao Wang, Christopher Orr, Jeannette Hacker-Stratton, Mohamed El-Shahawy, Keiko Omori, Meirigeng Qi, Fouad Kandeel

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Clinical characteristics and outcomes of incident haemodialysis-treated adult patients in Kenya: Brief paper about basic research by Samuel K. Kabinga, Seth O. McLigeyo, Anson K. Mwango, Davies O. Otieno, Evans A. Onyango, Priscah D. Chemutai, Duncan G. Irungu, John N. Ndungu

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Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth by Li Cao, Junling Wu, Qiang Zhang, Bashayer Baras, Ghalia Bhadila, Yuncong Li, Mary Anne S. Melo, Michael D. Weir, Yuxing Bai, Ning Zhang, Hockin H. K. Xu

“…This article reviews the cutting-edge research on a new class of bioactive and therapeutic dental resins, cements, and adhesives that can inhibit biofilms and protect tooth structures. …”
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