Attention to children with bronchiolitis: general clinical-therapeutic considerations by Juan Carlos Yanes Macías, Mercedes Fonseca Hernandez, Ileana García Rodriguez, Caridad Llul Tombo, Daimy Tio González, Juan Camilo Díaz Ceballos

“…General considerations, drawn up by consensus, are presented that highlight the clinical-therapeutic aspects of the disease and will facilitate the management of this condition at the primary and hospital level.…”
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Therapeutic potential of SOX family transcription factors in osteoarthritis by Yue Huang, Zhuo Wang

“…While SOX9 has been utilized as a biomarker to indicate the occurrence and prognosis of osteoarthritis, investigations into other members of the SOX family and the development of targeted treatments around SOX9 are still required.Purpose This article considers the impact of the SOX protein on the development and inhibition of osteoarthritis and highlights the need for therapeutic approaches targeting SOX9, as supported by existing research.Results SOX9 can contribute to the process of osteoarthritis through acetylation and ubiquitination modifications. …”
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Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer by Ge Cong, Xingyu Zhu, Xin Ru Chen, Hao Chen, Wei Chong

“…Some mechanisms of the occurrence and evolution of cancer still seem elusive even now. Consequently, the therapeutic strategies for cancer must continually evolve. …”
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Cardiac Outpouchings: Definitions, Differential Diagnosis, and Therapeutic Approach by Riccardo Scagliola, Gian Marco Rosa, Sara Seitun

“…This review aims to provide a comprehensive overview focusing on definition, differential diagnosis, and prognostic outcomes of cardiac outpouchings, as well as further insights on therapeutic options, in order to assist physicians in the most appropriate decision-making. …”
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Imetelstat as a novel therapeutic approach for myelodysplastic syndrome by Ammara Waheed Arain, Anushka Andani, Aayat Kashif, Radeyah Waseem

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Mitochondrial Dysfunction and Diabetic Nephropathy: Nontraditional Therapeutic Opportunities by Ping Na Zhang, Meng Qi Zhou, Jing Guo, Hui Juan Zheng, Jingyi Tang, Chao Zhang, Yu Ning Liu, Wei Jing Liu, Yao Xian Wang

“…Pharmacological regulation of mitochondrial networking is a promising therapeutic strategy for preventing and restoring renal function in DN. …”
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Zinc from an Essential Element to an Antiparasitic Therapeutic Agent by Maribel Navarro, Luana Vanessa Daniel, Legna Colina-Vegas, Gonzalo Visbal

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Hijacking of the nervous system in cancer: mechanism and therapeutic targets by Yu Zhang, Qili Liao, Xuyang Wen, Jiayan Fan, Tifei Yuan, Xuemei Tong, Renbing Jia, Peiwei Chai, Xianqun Fan

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Editorial: Tumor microenvironment complexity and its therapeutic implications by Denner Santos dos Anjos, Marxa Leão Figueiredo, Renee Laufer-Amorim, Carlos Eduardo Fonseca-Alves, Carlos Eduardo Fonseca-Alves, Carlos Eduardo Fonseca-Alves

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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches by Daiana Burdusel, Thorsten R. Doeppner, Roxana Surugiu, Dirk M. Hermann, Denissa Greta Olaru, Aurel Popa-Wagner

“…This narrative review underscores the need for continued research into the molecular mechanisms underlying these interactions and suggests future directions for therapeutic development, including clinical trials, biomarker discovery, and combination therapies that synergistically target aging processes.…”
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Genetic/Epigenetic Modulation, Ocular Diseases, and Therapeutic Prospective by Jingsheng Tuo, Lai Wei, Nan Hu

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The role of inflammasomes in hepatocellular carcinoma: Mechanisms and therapeutic insights by Valentina Arrè, Roberto Negro, Gianluigi Giannelli

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Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation by Prima Almazini

“…Additionally, for the latter, an integrated qualitative and quantitative assessment is essential to determine the optimal therapeutic strategy. According to the current guidelines, medical therapy remains the main treatment for functional mitral regurgitation. …”
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Skewed Epigenetics: An Alternative Therapeutic Option for Diabetes Complications by Gabriele Togliatto, Patrizia Dentelli, Maria Felice Brizzi

“…New healing options are urgently needed as current therapeutics are failing to improve long-term outcomes. …”
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Antibody Mediated Transduction of Therapeutic Proteins into Living Cells by James E. Hansen, Richard H. Weisbart, Robert N. Nishimura

“…Protein therapy refers to the direct delivery of therapeutic proteins to cells and tissues with the goal of ameliorating or modifying a disease process. …”
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Cuproptosis: molecular mechanisms, cancer prognosis, and therapeutic applications by Yating Cong, Na Li, Zixin Zhang, Yan Shang, Hailong Zhao

“…Our review also uncovers the potential therapeutic applications of copper chelators, copper ionophores, and copper-based nanomaterials in oncology. …”
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The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches by Pankita H. Pandya, Mary E. Murray, Karen E. Pollok, Jamie L. Renbarger

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Therapeutic proteins immunogenicity: a peptide point of view by Feliciana Real-Fernandez, Fosca Errante, Andrea Di Santo, Anna Maria Papini, Paolo Rovero

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Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…There is a dire need for the design of new and targeted therapeutic strategies that can overcome the drug resistance and improve the clinical outcome for patients diagnosed with the illness. …”
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Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine by Devang M. Patel, Jainy Shah, Anand S. Srivastava

“…This paper summarizes the current clinical and nonclinical data for the use of MSCs in tissue repair and potential therapeutic role in various diseases.…”
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