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The association between serum tacrolimus concentrations and BK viruria in kidney transplant recipients
Published 2025-01-01Subjects: Get full text
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Escherichia coli in the T11-12 Thoracic Vertebrae: A Case Report
Published 2025-02-01Subjects: Get full text
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To Measure or Not to Measure: Direct Oral Anticoagulant Laboratory Assay Monitoring in Clinical Practice
Published 2023-01-01“…The need for therapeutic drug monitoring of direct oral anticoagulants (DOACs) remains an area of clinical equipoise. …”
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26
Dosing of Ertapenem in an Extreme Obesity: A Case Report of 250 kg Patient
Published 2017-01-01“…The case suggests the usefulness of therapeutic drug monitoring of antibiotics, especially in critically ill patients.…”
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27
Clinical Chemistry : fundamentals and laboratory techniques /
Published 2017Table of Contents: “…John and Wendy Arneson -- Therapeutic drug monitoring and toxicology / Dean L. Arneson and Wendy Arneson.…”
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28
A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin
Published 2022-01-01“…This combination therapy may increase the risk of developing renal dysfunction, but the risk can be mitigated by appropriate therapeutic drug monitoring (TDM) and dose adjustments to achieve successful treatment.…”
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Ataxia and Seizures despite Phenytoin: A Case Report Highlighting the Importance of TDM and Genetic Influences
Published 2024-01-01“…Laboratory tests and imaging were inconclusive, leading to a therapeutic drug monitoring (TDM) consultation, which revealed elevated phenytoin levels. …”
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Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study
Published 2025-02-01“…It has been successfully applied to the pharmacokinetic studies of PPIs and P-CABs, offering a valuable tool for clinical research and therapeutic drug monitoring.Keywords: acid-suppressing drugs, PPIs, P-CAB, UPLC-MS/MS…”
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31
One-Step Solid Extraction for Simultaneous Determination of Eleven Commonly Used Anticancer Drugs and One Active Metabolite in Human Plasma by HPLC-MS/MS
Published 2018-01-01“…Therapeutic drug monitoring for anticancer drugs could timely reflect in vivo drug exposure, and it was a powerful tool for adjusting and maintaining drug concentration into a reasonable range, so that an enhanced efficacy and declined adverse reactions could be achieved. …”
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Tacrolimus Toxicity due to Biliary Obstruction in a Combined Kidney and Liver Transplant Recipient
Published 2017-01-01“…The immunosuppressant tacrolimus has a narrow therapeutic window, necessitating therapeutic drug monitoring to maintain efficacy and minimise toxicity. …”
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33
Clinical Biochemistry /
Published 2017Table of Contents: “…Biochemical investigations and quality control / David Cameron -- Automation / Tim James -- Kidney disease / Edmund Lamb -- Hyperuricaemia and gout / Joanne Marsden -- Fluid and electrolyte disorders / Tim James -- Acid-base disorders / David Tierney -- Clinical enzymology and biomarkers / Paul Collinson, Amy Lloyd -- Liver function tests / Roy Sherwood -- Abnormalities of lipid metabolism / Mike France -- Disorders of calcium, phosphate, and magnesium homeostasis / Nessar Ahmed -- Abnormal pituitary function ; Thyroid disease / Garry McDowell -- Diabetes mellitus and hypoglycaemia / Allen Yates, Ian Laing -- Adrenal disease / John Honour -- Reproductive endocrinology / Ian Laing, Julie Thornton -- Biochemical nutrition / Pat Twomey, William Simpson -- Gastrointestinal disorders and malabsorption / Garry McDowell, Gordon Brydon -- Specific protein markers / Gerald Maguire -- Cancer biochemistry and tumour markers / Joanne Adaway, Gilbert Wieringa -- Inherited metabolic disorders and newborn screening / Mary Anne Preece -- Therapeutic drug monitoring / Robin Whelpton, Nigel Brown, Robert Flanagan -- Chemical toxicology / Gwendolen Ayers.…”
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Clinical Biochemistry ; fundamentals of biomedical science /
Published 2017Table of Contents: “…Biochemical investigations and quality control / David Cameron -- Automation / Tim James -- Kidney disease / Edmund Lamb -- Hyperuricaemia and gout / Joanne Marsden -- Fluid and electrolyte disorders / Tim James -- Acid-base disorders / David Tierney -- Clinical enzymology and biomarkers / Paul Collinson, Amy Lloyd -- Liver function tests / Roy Sherwood -- Abnormalities of lipid metabolism / Mike France -- Disorders of calcium, phosphate, and magnesium homeostasis / Nessar Ahmed -- Abnormal pituitary function ; Thyroid disease / Garry McDowell -- Diabetes mellitus and hypoglycaemia / Allen Yates, Ian Laing -- Adrenal disease / John Honour -- Reproductive endocrinology / Ian Laing, Julie Thornton -- Biochemical nutrition / Pat Twomey, William Simpson -- Gastrointestinal disorders and malabsorption / Garry McDowell, Gordon Brydon -- Specific protein markers / Gerald Maguire -- Cancer biochemistry and tumour markers / Joanne Adaway, Gilbert Wieringa -- Inherited metabolic disorders and newborn screening / Mary Anne Preece -- Therapeutic drug monitoring / Robin Whelpton, Nigel Brown, Robert Flanagan -- Chemical toxicology / Gwendolen Ayers.…”
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35
Linezolid and tedizolid adverse effects: a review on serotonin syndrome, myelosuppression, neuropathies, and lactic acidosis
Published 2025-01-01“…Mitigation strategies, including the role of therapeutic drug monitoring, are also discussed.…”
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A Validated HPLC-DAD Method for Simultaneous Determination of Etodolac and Pantoprazole in Rat Plasma
Published 2014-01-01“…A simple, sensitive, and accurate HPLC-DAD method has been developed and validated for the simultaneous determination of pantoprazole and etodolac in rat plasma as a tool for therapeutic drug monitoring. Optimal chromatographic separation of the analytes was achieved on a Waters Symmetry C18 column using a mobile phase that consisted of phosphate buffer pH~4.0 as eluent A and acetonitrile as eluent B in a ratio of A : B, 55 : 45 v/v for 6 min, pumped isocratically at a flow rate of 0.8 mL min−1. …”
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Chromatographic Characterization and Method Development for Determination of Levetiracetam in Saliva: Application to Correlation with Plasma Levels
Published 2017-01-01“…A less invasive sampling method for therapeutic drug monitoring (TDM) would be very useful particularly for children. …”
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Validation of Simultaneous Quantitative Method of HIV Protease Inhibitors Atazanavir, Darunavir and Ritonavir in Human Plasma by UPLC-MS/MS
Published 2014-01-01“…The validated method can be useful in determining plasma concentration of these protease inhibitors for therapeutic drug monitoring and in high throughput clinical studies.…”
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Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma
Published 2019-01-01“…The proposed method was successfully applied to rifampicin quantification in 340 patients’ plasma samples, thus demonstrating its suitability for both therapeutic drug monitoring and pharmacokinetic analysis.…”
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Conductive Composite Biosensor System for Electrochemical Indinavir Drug Detection
Published 2015-01-01“…Multidrug combination therapy and, as such, therapeutic drug monitoring (TDM) during HIV/AIDS treatment are therefore critical, to prevent adverse interactions. …”
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