High Detection Rates for Prostate-specific Membrane Antigen–avid Prostate Cancer Recurrence at Low Prostate-specific Antigen levels on Extended Axial Field-of-view Positron Emissio... by Sarah Thomas, Jason Callahan, Paul Conway, Daniel Moon, Hugh Morgan, Johanna Ingbritsen, Melissa Munro, Robert E. Ware, Phil Dundee, Rodney J. Hicks

Get full text

A multi-modal multi-branch framework for retinal vessel segmentation using ultra-widefield fundus photographs by Qihang Xie, Qihang Xie, Xuefei Li, Yuanyuan Li, Yuanyuan Li, Jiayi Lu, Jiayi Lu, Shaodong Ma, Yitian Zhao, Yitian Zhao, Jiong Zhang, Jiong Zhang

Get full text

Dual-stream disentangled model for microvascular extraction in five datasets from multiple OCTA instruments by Xiaoyang Hu, Xiaoyang Hu, Jinkui Hao, Quanyong Yi, Yitian Zhao, Jiong Zhang

Get full text

Hybrid Graph Representation Learning for Carotid Artery Stenosis Detection Based on Multimodal Retinal OCTA Images by Wenting Lan, Jinkui Hao, Shengjun Zhou, Jingfeng Zhang, Shaodong Ma, Yitian Zhao

Get full text

A novel multi-scale and fine-grained network for large choroidal vessels segmentation in OCT by Wei Huang, Qifeng Yan, Lei Mou, Yitian Zhao, Wei Chen, Wei Chen, Wei Chen

Get full text

Prostate-Specific Membrane Antigen as Target for Neuroimaging of Central Nervous System Tumors by Brittany M. Stopa, James Crowley, Csaba Juhász, Cara M. Rogers, Mark R. Witcher, Jackson W. Kiser

“…Following the encouraging findings of several such case reports, there is a growing interest in the potential application of PSMA-targeted PET imaging for diagnostics, theranostics, and monitoring of CNS tumors. This is a systematic literature review on PSMA-binding tracers in CNS tumors. …”
Get full text

Stabilization of metal-doped magnesium oxide nanoparticles with PAMAM dendrimers to improve alpha-amylase enzyme inhibition by Jaison Jeevanandam, Mara Gonçalves, Rita Castro, Juan Gallo, Manuel Bañobre-López, João Rodrigues

Get full text

Computational insights into Sitahe (Leuconotis eugenifolia) bioactive compounds: A promising approach for radioprotection through p53 inhibition by Dian Pribadi Perkasa, Iin Kurnia, Taufik Muhammad Fakih, Teja Kisnanto, Dwi Ramadhani, Harry Nugroho Eko Surniyantoro, Boky Jeanne Tuasikal, Alfian Mahardika Forentin, Mukh Syaifudin

Get full text

Synthetic Approaches Toward Phosphorus-Containing BODIPY and Squaraine Dyes: Enhancing Versatility of Small-Molecule Fluorophores by Jeanne M. Favret, Sergei V. Dzyuba

“…These modifications often influence key spectroscopic properties and molecular functionality by expanding their utility in bioimaging, sensing, photosensitization, and theranostic applications. By leveraging the tunable nature of phosphorus-containing moieties, these dyes hold immense promise for addressing current challenges in spectroscopy, imaging, and material designs while unlocking new opportunities for advanced functional systems in chemistry, biology, and medicine.…”
Get full text

Release of biologically relevant substrates from prodrugs and nanocarriers using X- and γ-rays as trigger signals by Kumar, Amit, Dalko, Peter István

“…X- and γ-ray-excited theranostic techniques are increasingly being developed for biomedical applications, as they overcome the limitations of light penetration and tissue attenuation. …”
Get full text

Nano–bio surface interactions, cellular internalisation in cancer cells and e‐data portals of nanomaterials: A review by Ram Dhan Yadav, Abha Chaudhary

“…Abstract Nanomaterials (NMs) have abundant applications in areas such as electronics, energy, environment industries, biosensors, nano devices, theranostic platforms, etc. Nanoparticles can increase the solubility and stability of drug‐loaded materials, enhance their internalisation, protect them from initial destruction in the biological system, and lengthen their circulation time. …”
Get full text

A self-assembling nanoplatform for pyroptosis and ferroptosis enhanced cancer photoimmunotherapy by Zhichao Wang, Yuqi Tang, Quan Li

“…Herein, a multifunctional pH-responsive theranostic nanoplatform (M@P) is designed and constructed by self-assembly of aggregation-induced emission photosensitizer MTCN-3 and immunoadjuvant Poly(I: C), which are further encapsulated in amphiphilic polymers. …”
Get full text

Photothermal-enhanced silver nanocluster bioactive glass hydrogels for synergistic antimicrobial and promote wound healing by Fuqiang Song, Anqi Ye, Linyuan Jiang, Yang Lu, Yanzhen Feng, Rong Huang, Siting Du, Xiaoyu Dong, Ting Huang, Ping Li, Liangliang Yang, Jinjing Zhang, Mengjia Xu, Li Cheng, Jian Xiao

Get full text

Curing Temperature Effects on the Tensile Properties and Hardness of γ−Fe2O3 Reinforced PDMS Nanocomposites by Yvonne Konku-Asase, Abu Yaya, Kwabena Kan-Dapaah

“…The mechanical properties of plain polydimethylsiloxane (PDMS) and its nanocomposites have been exploited for various theranostic biomedical applications. Although several research groups have investigated the effects of preparation conditions—especially curing temperature and time—on bulk mechanical properties of plain PDMS, there are no reported similar studies for its nanocomposites. …”
Get full text

FITA-Containing 2,4-Dinitrophenyl Alkylthioether-Based Probe for Detection and Imaging of GSH by Yalun Dong, Liyue Wang, Wenfang Liang, Jiqin Zhu, Lu Sun, Long Yi

“…Probes for detection and imaging of GSH are not only useful for understanding GSH chemical biology but are also important for exploring potential theranostic agents. Herein, we report a fast intramolecular thiol-activated arylselenoamides (<b>FITA</b>)-based fluorescent probe using 2,4-dinitrophenyl alkylthioether as a sulfydryl-selective receptor for the first time. …”
Get full text

Advancements in Liposomal Nanomedicines: Innovative Formulations, Therapeutic Applications, and Future Directions in Precision Medicine by Izadiyan Z, Misran M, Kalantari K, Webster TJ, Kia P, Basrowi NA, Rasouli E, Shameli K

“…The integration of immunotherapeutic agents within liposomes marks a paradigm shift, enabling the design of ‘immuno-modulatory hubs’ capable of orchestrating precise immune responses while facilitating theranostic applications. The recent COVID-19 pandemic has accelerated research in liposomal-based vaccines and antiviral therapies, underscoring the need for improved delivery mechanisms to overcome challenges like rapid clearance and organ toxicity. …”
Get full text

Recent Advances in Indocyanine Green-Based Probes for Second Near-Infrared Fluorescence Imaging and Therapy by Dehong Hu, Menglei Zha, Hairong Zheng, Duyang Gao, Zonghai Sheng

“…Recent advancements in NIR-II imaging technology have revitalized interest in ICG, revealing its extended tail fluorescence beyond 1,000 nm and reaffirming its potential as a clinically translatable NIR-II fluorophore for in vivo imaging and theranostic applications for diagnosing various diseases. …”
Get full text

Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer? by Tryambak Pratap Srivastava, Ruby Dhar, Subhradip Karmakar

“…The systemic management of breast cancer is guided primarily by theranostic biomarkers; ER, PR, HER2, and Ki67 which also dictate the breast cancer classification. …”
Get full text

Rare Cell Population Analysis in Early-Stage Breast Cancer Patients by Stefan Schreier, Prapaphan Budchart, Suparerk Borwornpinyo, Lakkana Adireklarpwong, Prakasit Chirappapha, Wannapong Triampo, Panuwat Lertsithichai

“…Background: Circulating rare cells participate in breast cancer evolution as systemic components of the disease and thus, are a source of theranostic information. Exploration of cancer-associated rare cells is in its infancy. …”
Get full text

Direct imaging with multidimensional labelling and high‐content analysis allows quantitative categorization and characterizations of individual small extracellular vesicles and nan... by Simou Sun, Sarah J. Cox‐Vázquez, Nam‐Joon Cho, Guillermo C. Bazan, Jay T. Groves

“…This platform is poised to advance sEVP‐based theranostic assays and facilitate exploration into disease‐associated sEVP biogenesis and sEVP‐mediated intercellular communication.…”
Get full text