EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B by Yuyang Zhang, Mingqin Su, Yiming Chen, Li Cui, Wei Xia, Renfang Xu, Dong Xue, Xiansheng Zhang, Xingliang Feng

“…Abstract Background Chromosomal instability (CIN), a hallmark of cancer, is commonly linked to poor prognosis in high‐grade prostate cancer (PCa). …”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester-A primary cohort study with a scoping review. by Laura Ormesher, Jessica Catchpole, Linda Peacock, Heather Pitt, Anastasia Fabian-Hunt, Dexter Hayes, Claudia Popp, Jason M Carson, Raoul van Loon, Lynne Warrander, Karli Büchling, Alexander E P Heazell

“…However, fetal accelerations were less common in prone position (86% vs 95%, p = 0.03). Anxiety was reduced after the procedure, compared to beforehand (p = 0.002), despite a marginal decline in comfort (p = 0.04).The model predicted that if occlusion of the inferior vena cava occurred, the sBP, dBP and CO would generally decrease. …”
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Design, synthesis, structural characterization, in vitro anticancer activity, and in silico studies of some new hydroxylated and fluorinated-substituted hydrazone derivatives by Reşit Çakmak, Eyüp Başaran, Ömer Erdoğan, Suraj N. Mali, Semiha Köprü, Haya Yasin, Shailesh S. Gurav, Giray Topal

“…In this study, novel hydroxylated and fluorinated-substituted hydrazone derivatives bearing an aromatic nitro moiety (2a-d and 3a-d) were designed as potential anticancer drug candidates, synthesized for the first time, and evaluated for their anticancer activity against chondrosarcoma (SW1353), a common primary malignant cartilage-forming tumor, neuroblastoma (SH-SY5Y), a type of brain cancer, and healthy (L929) cell lines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method for 24 h. …”
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A Systematic Review and Meta-analysis of Randomized Controlled Trials on Comparing Transabdominal Preperitoneal Versus Lichtenstein Operations for Primary Inguinal Hernia Repair by Muhammad Aslam Javed, Muhammad Arshad Abbas, Mudassar Murtaza, Wasif Majeed Chaudhry, Adnan Faisal, Muhammad Mohsin Gillani

“… Background: Inguinal hernia repair is a common surgical operation being performed worldwide, and the primary objective of hernia repair is to reduce recurrence, minimize complications, and robust recovery. …”
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Hubungan Daerah Tempat Tinggal dengan Gambaran Histopatologi Karsinoma Tiroid pada Masyarakat Sumatera Barat by Eka Putri, Daan Khambri, Selfi Renita Rusdji

“…Kata kunci: Gambaran histopatologi karsinoma tiroid, daerah tempat tinggal<br />Kata kunci: Gambaran histopatologi karsinoma tiroid, daerah tempat tinggal</p><p>Abstract<br />Thyroid carcinoma is the most common endocrine tumor and is increasing in incidence every year. …”
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Research progress of phosphogypsum-based backfill technology by Qiusong CHEN, Aixiang WU

“…The development of hydration products plays a decisive role in the strength of phosphogypsum-based backfill. Common hydration products include calcium silicate hydrate (C–S–H) gel, calcium aluminate hydrate (C–A–H) gel, AFt, calcite, and calcium hydroxide (Ca(OH)2). (3) The potential environmental pollution risk of phosphogypsum-based backfill was evaluated, and the existing phosphogypsum pretreatment technology and toxic element fixation mechanism were summarized. …”
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The prevalence and distribution of malaria in Mpumalanga Province before and during COVID-19 (2017 - 2022) by I Kleinhans, S Mahanjana, F Els, M Mabona, L A Pitso, G Malatje, G Kok, J Raman

“…Headaches and fever were the most common symptoms before and post COVID-19, while asymptomatic malaria carriage was higher during and post COVID (p<0.05). …”
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OPTIMALISASI VISIBILITAS MENGGUNAKAN SPACE SYNTAX: STUDI KASUS GEDUNG GALERI NUSANTARA SEMARANG by Alifiano Rezka Adi, Muhammad Rizqi

“…The low R2 values are more common in panel board arrangements because there are areas with low visibility within a fairly wide coverage area. …”
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Eating difficulties among Nigerian community-dwelling stroke survivors: prevalence, correlates, and association with quality of life by Adekola B. Ademoyegun, Adebukola G. Ibitoye, Wasiu A. Rasaq, Oluwafunmilayo A. Adeniyi, David O. Fabuluje, Israel A. Ojo, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Although eating difficulties (EDs) are common after stroke, few studies are reporting their impact on the quality of life (QoL) of stroke survivors. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…Consistent with prior studies, the most commonly mutated genes included TRAF3, FBXW7, POT1, TP53, SETD2, DDX3X and TBL1XR1. …”
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Cardiac manifestations of Fabry disease in G3Stg/GlaKO and GlaKO mouse models-Translation to Fabry disease patients. by Abirami Kugadas, Pietro Artoni, Wanida Ruangsiriluk, Meng Zhao, Natalia Boukharov, Rizwana Islam, Dmitri Volfson, Katayoun Derakhchan

“…Current treatments can preserve kidney function but are not very effective in preventing progression of cardiovascular pathology which remains the most common cause of premature death in FD patients. There is a significant need for a translational model that could be used for testing cardiac efficacy of new drugs. …”
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Spatial Distribution Characteristics of Micronutrients and Their Deficiency Effect on the Root Morphology and Architecture in Citrus Rootstock by Gaofeng Zhou, Yiping Fu, Mei Yang, Yanhong Li, Jing Zhang

“…To clarify the spatial distribution characteristics of essential nutrients in citrus roots and the influence mechanism of micronutrient deficiency on citrus root morphology and architecture, especially the effects on lateral root (LR) growth and development, two commonly used citrus rootstocks, trifoliate orange (<i>Poncirus trifoliata</i> L. …”
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NEWCOMBO PROBLEMA IR AMERIKIETIŠKAS KLAUSIMAS by Zenonas Norkus

“…So the actor's rationality or its absence is the common cause of actor's "bad news, small benefit" choices and of Predictor's predictions who is discriminating against the bright actors (including all causal decision theorists, of course) by providing for them no opportunity to avoid undesirable state. …”
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Effect of temporal water restrictions on drinking behavior and time budget in lactating dairy cows according to their position in the social hierarchy within the herd by E. Nizzi, O. Dhumez, C. Hurtaud, A. Boudon

“…This study examined how different types of temporary water restriction, similar to those commonly encountered on farms, may affect the individual behavior and physiological dehydration status of cows and whether these effects could differ according to the cow's position in the social hierarchy of the group. …”
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Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study by Ibdah R, Al-Nusair M, Abuhalimeh R, Mahmoud SA, Laswi B, Rawashdeh S, Hamoudeh A, Kheirallah KA

“…Bivariate analyses and logistic regression models were used to predict independent risk factors of ACS using adjusted odds ratios (AOR) and 95% confidence intervals (CI).Results: The study included 572 young women (≤ 50-years) with a median age of 45-years, divided into an ACS group (n=154, 26.9%) and a control group with no atherosclerotic cardiovascular disease (n=418, 73.1%). The most common presentation of ACS was non-ST-elevation ACS (n=98, 64%). …”
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Safety profile of sacituzumab govitecan in patients with breast cancer: A systematic review and meta-analysis by Maria Inez Dacoregio, Isabella Michelon, Caio Ernesto do Rego Castro, Francisco Cezar Aquino de Moraes, Guilherme Rossato de Almeida, Lis Victória Ravani, Maysa Vilbert, Ricardo Lima Barros Costa

“…Most patients had triple negative BC (54.4 %, n = 505), metastatic disease (89.8 %, n = 833), and were heavily pretreated (at least two lines of prior therapy). Most common all-grade adverse events (AEs) were: neutropenia (70 %, 95 % CI, 64–76 %), followed by nausea (62 %, 95 % CI, 55–68 %), diarrhea (54 %, 95 % CI 47–60 %) and anemia (51 %, 95 % CI, 38–65 %). …”
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Exploration of Degradation Mechanism of Chlorogenic Acids in Stevia Based on UPLC-QTOF MS/MS by Juan-juan WU, Zi-xuan WANG, Yun-he LIAN, Li-juan HOU, Zhi-ping NIU, Wen-chang WANG, Di WU

“…In acidic or alkaline conditions, hydrolysis and structural transformations are common degradation pathways observed. In summary, dehydration, degradation, hydrolysis, and isomerization are four potential pathways of loss for stevia-derived chlorogenic acids subjected to environmental fluctuations. …”
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Çocuklarda Dental Anksiyete: Başarılı Dental Tedavinin Önündeki Engel by Aysun Avşar, Büşra Mutlu

“…Factors causing dental anxiety, one of the most common global barriers to dental treatments; can be grouped under 3 headings as dental, environmental and individual. …”
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NEWCOMBO PROBLEMA IR AMERIKIETIŠKAS KLAUSIMAS by Zenonas Norkus

“…So the actor's rationality or its absence is the common cause of actor's "bad news, small benefit" choices and of Predictor's predictions who is discriminating against the bright actors (including all causal decision theorists, of course) by providing for them no opportunity to avoid undesirable state. …”
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Quantification of regional net CO₂ flux errors in the Orbiting Carbon Observatory-2 (OCO-2) v10 model intercomparison project (MIP) ensemble using airborne measurements by J. Yun, J. Liu, J. Liu, B. Byrne, B. Weir, B. Weir, L. E. Ott, K. McKain, B. C. Baier, L. V. Gatti, S. C. Biraud

“…This suggests the presence of systematic biases in the inversion estimates associated with errors in the prescribed fossil fuel emissions common to all models. Our study emphasizes the value of airborne measurements for quantifying regional errors in ensemble net CO<span class="inline-formula">₂</span> flux estimates.…”
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