Emergency medicine pharmacists’ interventions in the tertiary hospitals’ emergency departments in Malaysia by Hock Peng Koh, Haliza Ab Jalal, Yee Ping Koo, Mary Siew Yng Chen, Manimegahlai Selvaratanam, Anaanthan Bhuvanendran Pillai, Wai Kit Wong, Xin Nee Guee, Sherene Su Ann Tan, Shirlyn Tan, Lih Jiuan Teh, Rosalind Guen Lin Sia

“…Insulin, enoxaparin, and noradrenaline were the most intervened HAMs.Conclusion: Inappropriate treatment regimens were the most common intervention category done by EM pharmacists in Malaysia. …”
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Sandpiper Optimization Algorithm With Region Growing Based Robust Retinal Blood Vessel Segmentation Approach by Ibrahim AlMohimeed, Mohamed Yacin Sikkandar, A. Mohanarathinam, Velmurugan Subbiah Parvathy, Mohamad Khairi Ishak, Faten Khalid Karim, Samih M. Mostafa

“…Retinal blood vessel examination is commonly utilized for retinal disease diagnosis by ophthalmologists. …”
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Evaluation of the merit of ethanolic extract of Annona reticulata as an anti-cancer agent in human colon cancer cell lines (HCT-116) [version 2; peer review: 2 approved, 1 not appr... by Sri Pragnya Cheruku, Krishnananda Prabhu, Akshatha G Nayak, Vijetha Shenoy Belle, Vanishree Rao, Pooja Prakash Rao, Nitesh Kumar

“…Background Colon cancer is the third most common cancer type worldwide. Novel alternative therapeutic anti-cancer drugs against colon cancer with less toxicity are to be explored . …”
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Addressing the gap in preterm resuscitation practices in high-income and low-middle income countries: a multicenter survey of the Asian neonatal network collaboration by Rinawati Rohsiswatmo, Rizalya Dewi, Jennie Sutantio, Zubair Amin, Young-Ah Youn, Sae Yun Kim, Su Jin Cho, Yun Sil Chang, Satoshi Kusuda, Fuyu Miyake, Tetsuya Isayama

“…Equipment availability during resuscitation was also variable; saturation monitors, radiant warmers, and plastic wraps were available in almost all hospitals, whereas oxygen and air blenders, heated humidified gas, and end-tidal CO2 detectors were more available in HICs. The most common device for Positive Pressure Ventilation (PPV) was the T-piece resuscitator (52.3%).ConclusionThe neonatal resuscitation practices for extremely preterm infants, encompassing staff, equipment, and guidelines, exhibited variance between HICs and LMICs in the AsianNeo region. …”
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Maize Herbivore-Induced Volatiles Enhance Xenobiotic Detoxification in Larvae of <i>Spodoptera frugiperda</i> and <i>S. litura</i> by Peng Wang, Qiyue Zeng, Yi Zhao, Xiaomin Sun, Yongqiang Han, Rensen Zeng, Yuanyuan Song, Dongmei Chen, Yibin Lin

“…Larval exposure of the invasive alien species <i>S. frugiperda</i> to maize HIPVs significantly enhanced their tolerance to all three of the well-known defensive compounds 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA), chlorogenic acid, and tannic acid in maize and the two commonly used insecticides methomyl and chlorpyrifos. …”
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Identification and Functional Analysis of PANoptosis‐Associated Genes in the Progression From Sepsis to ARDS by Zhong‐Hua Lu, Yan Tang, Hu Chen, Feng Liu, Mei Liu, Lu Fu, Xian‐Kai Wang, Ming‐Juan Li, Wei‐Li Yu, Yun Sun

“…ABSTRACT Background Sepsis and acute respiratory distress syndrome (ARDS) are common inflammatory conditions in intensive care, with ARDS significantly increasing mortality in septic patients. …”
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The efficacy of conservative management of micro-traumatic posterior shoulder instability by Lyn Watson, Prof DocBAppSci(Physio) GradDip, Simon Balster, BPhty(Hon), BSc (Hon), Sarah Warby, PhDB Physio (Hon), Ross Lenssen, BHSc(Physiotherapy), Gregory Hoy, MBBS, FRACS, FAOrthA, FACSP, Shane Barwood, MBBS, FRACS, Jacqui French, BPhysio, Bonnie Kerr, BHth ScMSports Physio, Sam Lawrence, DPT, BAppSc, PGCert, Charlotte Ganderton, PhDB Physio (Hon), Katherine Davis, BHuman Movt (ExSci), MPhysio, Tania Pizzari, PhDB Physio (Hon)

“…Background: Microtraumatic posterior shoulder instability (PSI) is characterized by symptomatic posterior translation of the glenohumeral joint. A common etiology is a gradual overload of glenohumeral joint structures. …”
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Study on stress corrosion behavior and failure mechanism of galvanized bolts in complex coal mine environments by Zhe He, Nong Zhang, Zhengzheng Xie, Chao Ma, Changliang Han, Fan Zhang, Huiqing Wang, Saad S. Alarifi

“…The premature failure of bolts caused by stress corrosion cracking (SCC) is a common issue in the global mining industry. Studies have shown that hot-dip galvanizing is an effective solution, but the first widespread application of galvanized bolts in Xin’Shang’Hai No. 1 coal mine, China, experienced extensive failures. …”
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Adolescents with Persistent Symptoms Following Acute SARS-CoV-2 Infection (Long-COVID): Symptom Profile, Clustering and Follow-Up Symptom Evaluation by Marco Floridia, Danilo Buonsenso, Laura Macculi, Liliana Elena Weimer, Marina Giuliano, Flavia Pricci, Leila Bianchi, Domenico Maurizio Toraldo, Graziano Onder, The ISS Long-COVID Study Group

“…Fatigue (62.9%) and dyspnea (43.3%) were the most common symptoms, followed by headache (28.9%), thoracic pain (22.7%), diarrhea (20.6%), palpitations/tachycardia (17.5%), articular pain (15.5%), difficult concentration (14.4%), muscle pain (12.4%), taste reduction (8.2%), smell reduction (8.2%), fever (6.2%), and skin disorders (5.2%). …”
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Long-term observations of black carbon and carbon monoxide in the Poker Flat Research Range, central Alaska, with a focus on forest wildfire emissions by T. Kinase, F. Taketani, F. Taketani, M. Takigawa, C. Zhu, Y. Kim, P. Mordovskoi, Y. Kanaya, Y. Kanaya

“…Sporadically large peaks in the BC mass concentration and CO mixing ratio were observed at the same time, indicating influences from common sources. These BC peaks coincided with peaks at other comparative sites in Alaska, indicating large BC emissions in interior Alaska. …”
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Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma by Lijuan Wang, Qian He, Weijun Qin, Xiyu Song, Yumeng Zhu, Wenwen Geng, Jianhua Jiao, Hongjiao Liu, Ruo Chen, Xiuxuan Sun, Jiejie Geng, Zhinan Chen

“…Background Clear cell renal cell carcinoma (ccRCC) is the most common histologic type of RCC. However, the spatial and functional heterogeneity of immunosuppressive cells and the mechanisms by which their interactions promote immunosuppression in the ccRCC have not been thoroughly investigated.Methods To further investigate the cellular and regional heterogeneity of ccRCC, we analyzed single-cell and spatial transcriptome RNA sequencing data from four patients, which were obtained from samples from multiple regions, including the tumor core, tumor-normal interface, and distal normal tissue. …”
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The effects of Lepidium meyenii on MSG-induced subfertility in male Wistar rats: Targeting oxidative stress, pro-inflammatory cytokines, steroidogenic enzymes, and reproductive hor... by Temidayo S. Omolaoye, Surendra Singh Rawat, Naglaa Gamil Shehab, Eslam El Nebrisi, Stefan S. Du Plessis

“…Objective and rationale: Although monosodium glutamate (MSG), commonly used to enrich food flavour, is generally considered safe for consumption, evidence has shown its adverse effects on physiological functions, including male reproduction, when consumed excessively. …”
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Comparative enrichment of complete ammonium oxidation bacteria in floccular sludge reactors: Sequencing batch reactor vs. continuous stirred tank reactor by Ying Zhu, Jiaying Hou, Fangang Meng, Meiying Xu, Limin Lin, Linyan Yang, Xueming Chen

“…This study attempted to compare the enrichment of complete ammonium oxidation (comammox) bacteria, which are affiliated with Nitrospira and not able to generate nitrous oxide (N2O, a potent greenhouse gas) through biological pathways, in two commonly-utilized configurations of floccular sludge reactors, i.e., sequencing batch reactor (SBR) and continuous stirred tank reactor (CSTR), under the ammonium condition of mainstream wastewater (i.e., 40.0 g-N/m3). …”
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CD21low B cells reveal a unique glycosylation pattern with hypersialylation and hyperfucosylation by Peter Tobias Felixberger, Peter Tobias Felixberger, Geoffroy Andrieux, Andrea Maul-Pavicic, Andrea Maul-Pavicic, Sigune Goldacker, Sigune Goldacker, Ina Harder, Ina Harder, Sylvia Gutenberger, Sylvia Gutenberger, Jonathan J. M. Landry, Vladimir Benes, Till Fabian Jakob, Melanie Boerries, Melanie Boerries, Lars Nitschke, Reinhard Edmund Voll, Reinhard Edmund Voll, Klaus Warnatz, Klaus Warnatz, Baerbel Keller, Baerbel Keller

“…In a subgroup of patients with common variable immunodeficiency (CVID), the occurrence of such complications is associated with an expansion of naïve-like CD21low B cells during a chronic type 1 immune activation. …”
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The impact of margins and re‐resection in pediatric synovial sarcoma by Andres F. Espinoza, Priya B. Shetty, Jillian C. Jacobson, Hannah Todd, Kelley Harrell, Alfred F. Trappey, John Doski, Eumenia C. Castro, Nicole I. Montgomery, M. Fatih Okcu, Rajkumar Venkatramani, Dai H. Chung, Sanjeev A. Vasudevan

“…Abstract Introduction Synovial sarcoma is one of the most common soft tissue sarcomas in children. Guidelines regarding the adequate extent of resection margins and the role of re‐resection are lacking. …”
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AnaDetect: An extensive dataset for advancing anemia detection, diagnostic methods, and predictive analytics in healthcareMendeley Data by Mayen Uddin Mojumdar, Dhiman Sarker, Md Assaduzzaman, Md. Anisul Haque Sajeeb, Md. Mohaimenur Rahman, Md Shadikul Bari, Shah Md Tanvir Siddiquee, Narayan Ranjan Chakraborty

“…Anemia is a critical medical condition in public health concern in tropical and subtropical areas, and understanding its hematological changes is crucial for improving diagnosis, treatment, and prognosis.It manifests through symptoms like weakness, fatigue, pale skin, and shortness of breath due to insufficient hemoglobin or red blood cells to carry adequate oxygen, with severe cases leading to complications such as chest pain. Common causes include blood loss, chronic diseases, and iron and vitamin deficiencies. …”
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Comprehensive analysis reveals cholesterol metabolism-related signature for predicting prognosis and guiding individualized treatment of glioma by Dengfeng Lu, Fei Wang, Yayi Yang, Aojie Duan, Yubo Ren, Yun Feng, Haiying Teng, Zhouqing Chen, Xiaoou Sun, Zhong Wang

“…Objective: Gliomas are the most common intracranial tumors with the highest degree of malignancy. …”
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Ethnobotany, floristic and phytochemical studies of medicinal plants used to treat uterine fibroids in Mbarara City, Uganda by Calton Nantinda, Esther Lynnet Kisakye, David Musana, Isaac Ssessanga, Ukashar Ssenabulya, Timothy Omara, Ivan Kahwa, Florence Nalimu

“…Uterine fibroids (UF) are the most common non-cancerous benign gynaecologic tumours in premenopausal females. …”
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Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial by Marion Thibaudin, Nicolas Roussot, Chloé Burlot, Antonin Schmitt, Julie Vincent, Zoé Tharin, Leila Bengrine, Hélène Bellio, Aurélie Bertaut, Léa Hampe, Susy Daumoine, Emilie Rederstorff, Morgane Peroz, Titouan Huppe, Valentin Derangère, David Rageot, John Simard, Caroline Truntzer, Jean David Fumet, Francois Ghiringhelli

“…No patient exhibited dose-limiting toxicity at any dose. The most common treatment-related adverse events (TRAE) of any grade (G) were diarrhoea (35.3%), nausea (47.1%) and anaemia (35.3%). …”
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Ice-nucleating particles active below −24&thinsp;°C in a Finnish boreal forest and their relationship to bioaerosols by F. Vogel, F. Vogel, M. P. Adams, L. Lacher, P. B. Foster, G. C. E. Porter, G. C. E. Porter, B. Bertozzi, B. Bertozzi, K. Höhler, J. Schneider, T. Schorr, N. S. Umo, J. Nadolny, Z. Brasseur, P. Heikkilä, E. S. Thomson, N. Büttner, M. I. Daily, R. Fösig, A. D. Harrison, J. Keskinen, U. Proske, U. Proske, U. Proske, J. Duplissy, J. Duplissy, M. Kulmala, T. Petäjä, O. Möhler, B. J. Murray

“…This study should motivate further work to establish whether the commonality in bioaerosol ice-nucleating properties between spring in Finland and summer in Colorado is more generally applicable to different coniferous forest locations and times and also to determine to what extent these bioaerosols are transported to locations where they may affect clouds.…”
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