Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developin... by Akihiko Kawahara, Tetsuro Sasada, Koichi Azuma, Hidenobu Ishii, Norikazu Matsuo, Takaaki Tokito, Tomoaki Hoshino, Yohei Miyagi, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Kenta Murotani

“…However, the clinical significance of free amino acids (plasma-free amino acids (PFAAs)) and tryptophan-related metabolites in plasma has not been fully understood in patients with non-small cell lung cancer (NSCLC) who receive immune checkpoint inhibitors.Methods We conducted a single cohort observational study. …”
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Real-world survival outcomes with immune checkpoint inhibitors in large-cell neuroendocrine tumors of lung by Samuel Kareff, Jair Bar, Amir Onn, Alona Zer, Chul Kim, Stephen V Liu, Elizabeth Dudnik, Mor Moskovitz, Anastasiya Lobachov, Teodor Gottfried, Damien Urban, Ofer Rotem, Mira Wollner

“…The patients were divided into group A (patients who received ICI, n=41) and group B (patients who did not receive ICI, n=84). …”
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Factors associated with the discontinuation of modern contraceptive methods among lactating women in nine West African high-fertility countries: findings of the most recent demogra... by Abou Coulibaly, Adama Baguiya, Denise Kpebo, Augustin Zango, Halima Tougri, Franck Garanet, Seni Kouanda

“…In addition, compared to implant users, women using pills (aPR = 3.06; 95% CI [2.24–4.16]; p < 0.001), those using injectables (aPR = 2.80; 95% CI [2.16–3.62]; p < 0.001), and women whose partners used condoms (aPR = 2.30; 95% CI [1.47–3.59]; p < 0.001) were more likely to discontinue contraception. Moreover, women who were not sexually active (aPR = 2.11; 95% CI [1.75–2.54]; p < 0.001) and those who wanted children within two subsequent years (aPR = 1.84; 95% CI [1.36–2.48]; p < 0.001) were more likely to discontinue contraception. …”
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Retrospective analysis of the occurrence, potential risk factors and medical significance of pulmonary complications after total shoulder arthroplasty from the National Inpatient S... by Mengning Dong, Huitong Liang, Jinlang Fu, Zeying Guo, Hao Xie, Qinfeng Yang, Qingmei Yu, Xiaomin Hou

“…Methods The National Inpatient Sample (NIS) was utilized to survey all patients who underwent primary elective TSA from 2010 to 2019. …”
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Reproduction outcomes and prognostic significance of pregnancy after nasopharyngeal carcinoma treatment by Meijuan Luo, Liting Liu, Zhenchong Yang, Yujing Liang, Dongxiang Wen, Sailan Liu, Xiaoyun Li, Chuanmiao Xie, Linquan Tang, Qiuyan Chen, Shanshan Guo, Haiqiang Mai

“…The median birth weight of newborns was 3.11 kg. Patients who delivered successfully were younger than those who had an abortion. …”
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‘It is scary to pause treatment’: perspectives on HIV cure-related research and analytical treatment interruptions from women diagnosed during acute HIV in Durban, South Africa: So... by Deli Mthimkhulu, Krista L. Dong, Mzwakhe Wiseman Ngcobo, Deborah Mindry, Ayanda Zulu, Ntombifuthi Langa, Luyanda Maphalala, Vanessa Pillay, Maud Mthembu, Annie Miall, Whitney Tran, Ana Dillen, Fang Wan, Ali Ahmed, Jamila K. Stockman, Maryam Hussain, Thumbi Ndung’u, Karine Dubé

“…Background HIV remains a major challenge in KwaZulu-Natal, South Africa, particularly for young women who face disproportionate risks and barriers to prevention and treatment. …”
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Seroprevalence of Human Herpesvirus Infections in Newly Diagnosed HIV-Infected Key Populations in Dar es Salaam, Tanzania by Doreen Kamori, Agricola Joachim, Mucho Mizinduko, Godfrey Barabona, Macdonald Mahiti, Upendo Kibwana, Mtebe Majigo, Salim Masoud, Ambele M. Mwandigha, Takamasa Ueno, Elia Mmbaga, Eligius Lyamuya

“…In the population at high risk of HIV infection, also termed as key populations (female sex workers (FSW), men who have sex with men (MSM), and people who inject drugs (PWID)), and their sexual partners, HHV infections can potentially compromise the efforts to prevent and control HIV infection. …”
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The effect of the relative dose intensity of chemoradiotherapy on the effectiveness of therapy of locally advanced unresectable non-small cell lung cancer by A. E. Glukhareva, G. V. Afonin, I. V. Kolobaev, L. Yu. Grivtsova, S. A. Ivanov, A.  D.  Kaprin

“…However, there is a cohort of patients who did not receive the planned amount of treatment, due to the high toxicity of simultaneous chemoradiotherapy. …”
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THE EFFECT OF NUTRITIONAL THERAPY ON QUALITY OF LIFE INDICATORS FOR PATIENTS WITH GASTRIC CANCER AT THE STAGE OF SURGICAL TREATMENT by A. D. Sergienko, V. E. Khoronenko, E. V. Gameeva, A. B. Ryabov, V. M. Khomyakov

“…Patients of the 1st group who received specialized nutritional mixtures, developed the statistical significance of the differences in the assessment of the quality of life upon admission and before discharge. …”
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Comparison of search and rescue operations involving emergency physicians in devastating earthquakes in Turkey: a 24-year experience study by Mustafa Ferudun Celikmen, Gülbin Aydoğdu Umaç, Melih Imamoglu, Mümin Murat Yazici, Elif Çiğdem Keleş, Sarper Yilmaz

“…Conclusion The 24 years of experience and expertise gained by EPs who served in Türkiye in these operations constitute a valuable global resource. …”
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Enhancing diagnostic outcomes in kidney genetic disorders: the KidGen national kidney genomics study protocol by Amali Mallawaarachchi, Hugh McCarthy, Thomas A. Forbes, Kushani Jayasinghe, Chirag Patel, Stephen I. Alexander, Tiffany Boughtwood, Jeffrey Braithwaite, Aron Chakera, Sam Crafter, Ira W. Deveson, Randall Faull, Trudie Harris, Lilian Johnstone, Matthew Jose, Anna Leaver, Melissa H. Little, Daniel MacArthur, Tessa Mattiske, Christine Mincham, Kathy Nicholls, Catherine Quinlan, Michael C. J. Quinn, Gopala Rangan, Jessica Ryan, Cas Simons, Ian Smyth, Madhivanan Sundaram, Peter Trnka, Laura Wedd, Erik Biros, Zornitza Stark, Andrew Mallett

“…Genetic investigations are increasingly used in nephrology practice; however, many patients who undergo testing still lack a definitive diagnosis. …”
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Surgical options for Evans-Jensen type IV intertrochanteric femur fractures in the elderly over 65: a comparison between total hip arthroplasty and proximal femoral nail antirotati... by Ming Sun, Hai-Rui Liang, He Zhang, Tong Bai, Rong-Da Xu, Si-Yu Duan, Zhen-Cun Cai, Zhen-Cun Cai

“…There was no significant difference in the overall incidence of postoperative complications between the two groups (p = 0.41).ConclusionFor elderly patients over 65 years old with Evans-Jensen Type IV intertrochanteric femur fractures, especially those with underlying diseases who cannot tolerate prolonged bed rest, hip replacement surgery (THA) may be preferred. …”
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Hubungan antara Kadar Troponin T dengan Luas Infark Miokard yang Diukur dengan Menggunakan Metode Skoring QRS Selvester pada Pasien Infark Miokard Akut by Muhammad Lingga Primananda, Masrul Syafri, Malinda Meinapuri3

“…<div class="WordSection1"><p><strong>Abstrak</strong></p><p>Dalam kriteria diagnosis IMA oleh WHO salah satunya apabila ditemukan peningkatan kadar enzim jantung. …”
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Determinants of Parental Attitudes towards Children’s Vaccination in Lithuania: An Online Survey by Kamilė Čeponytė, Eglė Narkevičiūtė, Aušra Beržanskytė, Sigita Burokienė

“…We found that 16.9% of parents who were unvaccinated as children themselves tend not to vaccinate their children. …”
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An evaluation of the effectiveness of an updated pre-service midwifery curriculum integrated with emergency obstetric and newborn care in Kenya: a cluster randomised controlled tri... by Duncan N. Shikuku, Catherine Mwaura, Peter Nandikove, Alphonce Uyara, Helen Allott, Lucy Waweru, Lucy Nyaga, Edna Tallam, Issak Bashir, Eunice Ndirangu, Carol Bedwell, Sarah Bar-Zeev, Charles Ameh

“…Overall performance in EmONC knowledge and skills was significantly higher for students who were taught by trained and mentored educators compared to those who received training alone. …”
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Assessment of clinical prognosis in autoimmune encephalitis: Girona score by Gary Álvarez Bravo, Giuseppe Guglielmini, Ana Quiroga Varela, Almudena Boix Lago, Ariadna Gifreu Fraixinó, Daniele Urso, Daniele Urso, Daniele Urso, Daniele Urso, Giancarlo Logroscino, Giancarlo Logroscino, Giancarlo Logroscino, Giancarlo Logroscino, Lluís Ramió-Torrentà

“…We identified that the mean initial score was significantly higher in the group of patients who had higher mRS at 3 months compared to that in the group of patients who had a mild to moderate disability level (mRS ≤ 2) at 3 months (p = 0.023). …”
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Autoimmune glial fibrillary acidic protein astrocytopathy misdiagnosed as intracranial infectious diseases: case reports and literature review by Runhua Bai, Runhua Bai, Li An, Wei Du, Zhiwei Wang, Xiaokun Qi, Jianguo Liu, Ming Ren, Yingxin Yu

“…Our study summarized a total of 40 patients with A-GFAP-A who were initially misdiagnosed as intracranial infections. …”
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Longitudinal Utilization of Invasive Pain Treatment Procedures Among Veterans with Chronic Pain Following Use of Whole Health Services and Complementary and Integrative Health Ther... by Zeliadt SB, DeFaccio R, Carey EP, Etingen B, Rosser EW, Suri P, Chen JA, Bokhour BG, Coggeshall S

“…Whole Health use was associated with 42% (− 61% to − 17%) lower utilization of invasive pain procedures at three months compared to matched patients who did not use Whole Health. This reduction was attenuated at 18 months: 22% (− 39% to − 5%). …”
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Efficacy and Safety of HAPC in Barrett's Esophagus – A Multicenter Italian Prospective Study by Davide Massimi, Roberta Maselli, Silvia Pecere, Cristiano Spada, Gianluca Andrisani, Francesco Maria Di Matteo, Antonella La Terra, Franco Coppola, Antonio Capogreco, Roberto De Sire, Ludovico Alfarone, Maddalena Menini, Marco Spadaccini, Cesare Hassan, Alessandro Repici

“…Among the 51 enrolled patients (mean C 0.43 cm (SD 0.72), mean M 2.20 cm (SD 1.09)) who completed the treatment (80 H-APC sessions), 45.1% (23/51) had prior ER of visible lesions . …”
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Toxicological Characterization of Six Plants of the Beninese Pharmacopoeia Used in the Treatment of Salmonellosis by Boris Legba, Victorien Dougnon, Esther Deguenon, Jerrold Agbankpe, Maximin Senou, Alidah Aniambossou, Carène Gbaguidi, Kevin Sintondji, Lamine Baba-Moussa, Jacques Dougnon

“…In general, the heavy metal contents of the extracts do not exceed the standards set by the WHO/FDA except for a few extracts. Arsenic was not detected in any extract, while aluminum and chromium were detected at levels above the WHO/FDA standards. …”
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