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31041
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study
Published 2025-01-01“…We conducted a UK multicentre case–control study of patients hospitalised with COVID-19 (controls) and those who developed COVID-19 associated acute neurological or psychiatric complications (cases). …”
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31042
Diversity in the medical research ecosystem: a descriptive scientometric analysis of over 49 000 studies and 150 000 authors published in high-impact medical journals between 2007...
Published 2025-01-01“…To evaluate disparities in gender and geographical representation among authors who have published in any of five top general medical journals, we conducted scientometric analyses using a large-scale dataset extracted from the New England Journal of Medicine, Journal of the American Medical Association, The BMJ, The Lancet and Nature Medicine.Methods Author metadata from all articles published in the selected journals between 2007 and 2022 were collected using the DimensionsAI platform. …”
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31043
Definitional differences in “outpatient” surgery can influence study outcomes related to total shoulder arthroplasty
Published 2025-01-01“…Methods: The American College of Surgeons National Surgical Quality Improvement Program database was queried for patients who underwent TSA between 2011 and 2021. HDO cases were identified based on the National Surgical Quality Improvement Program inpatient or outpatient variable, and SDD cases were identified based on length of stay = 0. …”
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31044
Comparison of the lethal triad and the lethal diamond in severe trauma patients: a multicenter cohort
Published 2025-01-01“…The patients included in this study were all trauma patients who had received transfusions of at least 1 unit of red blood cells (RBCs) within the first 6 h of hospital admission and for whom ionized calcium measurements were available. …”
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31045
A multicenter retrospective study of early cardiac toxicity in operable breast cancer patients receiving concurrent dual or mono anti-HER2 therapy with postoperative radiation ther...
Published 2025-02-01“…Dosimetric analysis showed that patients who developed subclinical cardiac events had increased mean heart dose (412.0 ± 249.6 vs. 347.2 ± 242.6 cGy, P-value = 0.010). …”
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31046
Interventional therapy and perioperative nursing management of Budd-Chiari syndrome: A report of 139 cases (布-加综合征的介入治疗及围术期护理管理: 附139例报告)...
Published 2023-04-01“…Methods The clinical data of 139 patients with BCS who received endovascular treatment in our hospital from December 2012 to December 2019 were retrospectively analyzed. …”
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31047
Impact of Late Ventricular Arrhythmias on Cardiac Mortality in Patients with Acute Myocardial Infarction
Published 2019-01-01“…Moreover, independent predictors of in-hospital cardiac mortality among patients with AMI who had sustained VT/VF were higher peak CK-MB [Odds ratio (OR: 1.001, 95%confidence interval (CI): 1.000-1.002, p= 0.03)], higher Killip class (OR: 1.484, 95%CI 1.017-2.165, p= 0.04), and late VT/VF (OR: 3.436, 95%CI 1.115-10.59, p= 0.03). …”
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31048
Examining the effect of direct-from-blood bacterial testing on antibiotic administration and clinical outcomes: a protocol and statistical analysis plan for a pragmatic randomised...
Published 2025-01-01“…The trial will enrol 500 adult patients presenting to the emergency department at Vanderbilt University Medical Center with suspected bacterial infection who have been initiated on empiric intravenous vancomycin. …”
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31049
Prevalence and management of hypertension in Turner syndrome: data from the International Turner Syndrome (I-TS) registry
Published 2025-01-01“…Objective: To investigate the prevalence and patterns of hypertension diagnosis and management in adult patients with TS who are registered in a large international multicentre database (TS-HTN study). …”
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31050
Safety and efficacy of the therapeutic DNA-based vaccine VB10.16 in combination with atezolizumab in persistent, recurrent or metastatic HPV16-positive cervical cancer: a multicent...
Published 2025-01-01“…ORR was assessed in the efficacy population, being all response-evaluable patients who received any administration of VB10.16 and atezolizumab and had at least one post-baseline imaging assessment.Results Between June 16, 2020, and January 25, 2022, 52 patients received at least one administration of study treatment. …”
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31051
Relationship between four healthy lifestyle factors and all-cause and cardiovascular disease mortality among residents aged 35 – 75 years in Hebei province
Published 2024-12-01“…MethodsData were collected from 48 377 residents aged 35 – 75 years in 11 districts and counties of Hebei province (Daming county, Handan city; Qinghe county, Xingtai city; Xuanhua district, Zhangjiakou city; Yuhua district, Shijiazhuang city; Chengde county, Chengde city; Sanhe city, Langfang city; Quyang county, Baoding city; Huanghua city, Cangzhou city; Shenzhou city, Hengshui city; Zunhua city, Tangshan city; and Funing district, Qinhuangdao city) who participated in the National Early Screening and Comprehensive Intervention Program for High-Risk Populations of CVD from September 2016 to December 2022. …”
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31052
Validation of ACC/AHA and ESC Sudden Cardiac Death Risk Guidelines in Diverse Hypertrophic Cardiomyopathy Cohort: Stratification HCM Study
Published 2024-12-01“…Methods: This retrospective cohort study included patients diagnosed with HCM who were followed in a dedicated clinic at a tertiary hospital in Brazil. …”
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31053
Risankizumab Versus Secukinumab: A Real-World Efficacy and Cost per Responder Comparison in Patients With Psoriasis in Italy
Published 2025-01-01“…Methods:.A multicentric retrospective study was conducted in patients from the Lazio region of Italy affected by moderate-to-severe psoriasis who initiated risankizumab or secukinumab between September 2020 to September 2022. …”
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31054
Effect of laser lithotripsy of giant bile duct stones under endoscopic retrograde cholangiopancreatography and nursing management (内镜逆行胰胆管造影术下胆总管巨大结石激光碎石效果观察及护理)...
Published 2023-02-01“…Methods From May 2018 to May 2022, the clinical data of 200 patients with common bile duct stones who underwent ERCP treatment and lithotripsy were retrospectively analyzed, of which 69 patients were treated with dual-frequency dual-pulse laser lithotripsy (Laser group) and 131 patients were treated with mechanical lithotripsy (Mechanical group), and the success rate of stone extraction, operation time, postoperative hospital stay time and complications of two groups of patients were compared. …”
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31055
Application of home-based exercise therapy in community-dwelling elderly patients with mild cognitive impairment and depression (以家庭为基础的运动疗法在社区老年轻度认知障碍伴抑郁患者中的应用研究)...
Published 2023-11-01“…Methods From January 2021 to December 2022, 60 community-dwelling elderly patients with MCI and depression who were screened at medical institutions were randomly divided into the control group and the intervention group. …”
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31056
Analyzing Expressions of the Design Argument and Answering Doubts Attributed to it Based on the Type of Logical Reasoning
Published 2024-05-01“…Various expressions of this argument with different degrees of strength and accuracy are seen in the talk of Islamic and Western thinkers who through argument, analogy, or induction and with dependence on partial or general instances of design in nature are trying to prove an intelligent moderator. …”
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31057
Fatty Acids of Erythrocyte Membranes and Blood Serum as Possible Predictors of Exacerbation in Patients with Inflammatory Bowel Diseases
Published 2025-02-01“…In the acute stage, patients with IBD have a higher total content of saturated fatty acids (SFAs) in erythrocyte membranes compared to the control group (p = 0.006), and, on the contrary, lower levels of unsaturated fatty acids (UFAs) (p = 0.005), mainly due to polyunsaturated FAs (PUFAs) (p = 0.026), namely omega-6 PUFAs (p = 0.011).Remission of IBD is associated with an increase in the level of a number of SFAs in the blood serum — margaric C17:0 (p = 0.024), arachidic acid (C20:0) — in erythrocyte membranes and serum (p = 0.0001 and p = 0.019, respectively), with a decrease in the total content of monounsaturated FAs in erythrocyte membranes (p = 0.022), an increase in the total concentration of PUFAs due to both omega-3 PUFAs (p = 0.0008) and omega-6 PUFAs (p = 0.033) in erythrocyte membranes compared with a group of healthy individuals.The exacerbation stage in patients with IBD examined over time is associated with higher levels of stearic FA C18:0 (p = 0.005), SFA/UFA (p = 0.034) and SFA/PUFA (p = 0.039) ratios in erythrocyte membranes, serum level of arachidic FA C20:0 (p = 0.008), and, on the contrary, lower content of UFAs in erythrocyte membranes — eicosapentaenoic C20:5n-3 (p = 0.0023), eicosadienoic C20:2n-6 (p = 0.0027), hexadecadienoic C16:2n-6 (p = 0.006), docosatetraenoic C22:4n-6 (p = 0.008) and alpha-linolenic C18:3n-3 (p = 0.039).A combined “panel” of fatty acids, including the levels of C20:2n-6, C18:0 in erythrocyte membranes and the content of C20:0 in blood serum, provided an AUC of 0.683 (95 % CI: 0.500–0.844), sensitivity 91.4 %, specificity 68.3 %.Levels of C20:5n-3, C20:2n-6, C18:0, C16:2n-6, C22:4n-6, C18:3n-3 fatty acids, SFA/UFA and SFA/PUFA ratios in erythrocyte membranes and content C20:0 in blood serum, used as biomarkers — predictors of the development of exacerbation in patients with IBD who were in remission, predicted the development of exacerbation of IBD after 2–4 months in the case of maximally changed levels of FAs, after 6–8 months — with moderately changed levels FAs, maintaining remission for 12 months — with minimally changed FAs levels.Conclusion. …”
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31058
Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study
Published 2016-12-01“…To ensure detailed understanding of issues of importance, qualitative interviews will be undertaken with a sample of men who complete the survey across the UK (n=∼150) along with a small number of partners/spouses (n=∼30).Ethics and dissemination The study has received the following approvals: Newcastle and North Tyneside 1 Research Ethics Committee (15/NE/0036), Health Research Authority Confidentiality Advisory Group (15/CAG/0110), NHS Scotland Public Benefit and Privacy Panel (0516-0364), Office of Research Ethics Northern Ireland (16/NI/0073) and NHS R&D approval from Wales, Scotland and Northern Ireland. …”
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31059
Acute gastrointestinal and post-acute COVID-19 gastrointestinal syndrome assessment on the Gastrointestinal Symptom Rating Scale scoring system: A questionnaire-based survey
Published 2024-12-01“…Exclusion criteria were neurological disorders, dementia, inability to understand Hindi/English languages, and psychiatric problems. All patients who met the inclusion criteria were telephonically called from November 2023 to January 2024. …”
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31060