Shorter telomere length in COPD cases secondary to biomass-burning smoke exposure by Angélica Domínguez-de-Barros, Gloria Pérez-Rubio, Ingrid Fricke-Galindo, Alejandra Ramírez-Venegas, Malena Gajate-Arenas, Rafael Hernández-Zenteno, Salvador García-Carmona, Robinson Robles-Hernández, María E. Ramírez-Díaz, Filiberto Cruz-Vicente, María L. Martínez-Gómez, Jacob Lorenzo-Morales, Ramcés Falfán-Valencia, Elizabeth Córdoba-Lanús

“…Conclusions This is the first study to document that individuals with COPD secondary to biomass smoke exposure present shorter telomeres than BS-exposed subjects who did not develop the disease.…”
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Percutaneous unilateral biportal endoscopic discectomy for symptomatic lumbar disc herniation in geriatric patients by Rongqing Qin, Rongqing Qin, Anhong Guan, Anhong Guan, Min Zhu, Pin Zhou, Bing Zhou, Bing Zhou, Ruihua Zhou, Ruihua Zhou, Zaiyong Guan, Zaiyong Guan

“…PurposeThe purpose of this study is to investigate the surgical efficacy and safety of percutaneous unilateral biportal endoscopic discectomy (UBED) for symptomatic lumbar disc herniation (LDH) in geriatric patients.MethodsSeventy-two geriatric patients, aged 65–86 years (mean age: 73.2 years), with single or two-level LDH who underwent UBED from January 2020 to September 2022 were retrospectively analyzed. …”
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Identification of biomarkers for tumor regression grade in esophageal squamous cell carcinoma patients after neoadjuvant chemoradiotherapy by Zhifu Chen, Yan Wang, Jun Chen, Zijun Xu, Tingjuan Zhang, Lu Sun, Lihua Zhu, Liben Xu, Chaoyang Wu, Zhiyuan Qiu, Dianjun Wang, Ting Wu

“…MMP9, NFIX, and GPR56 were identified as candidate genes, and their expression and correlation with prognosis were evaluated by immunohistochemical analysis.ResultsAmong 60 ESCC patients who underwent surgery after NCRT, the pathological complete response (pCR) rate was 35.0% (21/60), and the major pathological response (MPR) rate was 60.0% (36/60). …”
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Health checks for autistic adults: study protocol for a cluster randomised controlled trial by Jeremy R. Parr, Helen Taylor, Colin Wilson, Clare Scarlett, Sarah Al-Asmori, Carole Buckley, Sally-Ann Cooper, Cristina Fernandez-Garcia, Tracy Finch, Rhianna Lees, Nicholas Lennox, Hannah Merrick, Sebastian Moss, Christina Nicolaidis, Malcolm Osbourne, Dora M. Raymaker, Tomos Robinson, Anna Urbanowicz, James M. S. Wason, Barry Ingham

“…Two hundred autistic adults (aged 18 years and over) who provide baseline data will be recruited via participating practices. …”
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Analisis Faktor dan Metode untuk Menentukan Tipe Kulit Wajah: Tinjauan Literatur by Shinta Dewi Kusumaningrum, Izzati Muhimmah

“…The results of this literature review provide an overview of studies that are relevant to the topic, the differences in each literature discussed and are useful for researchers who will develop image processing technology to determine the type of facial skin. …”
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Preoperative prediction of lymphovascular invasion and T-staging of rectal cancer via a dual-energy computed tomography iodine map: a feasibility study by Jinliang Zhang, Hui Qi, Chun Yang, Ling Liu, Yuxin Wang, Wei Li

“…METHODS: Forty-nine patients with RC who had not received radiotherapy were enrolled to undergo a DECT scan. …”
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A Vitamin Pattern Diet Is Associated with Decreased Risk of Gestational Diabetes Mellitus in Chinese Women: Results from a Case Control Study in Taiyuan, China by Qiong Chen, Yongliang Feng, Hailan Yang, Weiwei Wu, Ping Zhang, Keke Wang, Ying Wang, Jamie Ko, Jiaxin Shen, Lingling Guo, Feng Zhao, Wenqiong Du, Shouhang Ru, Suping Wang, Yawei Zhang

“…The significant reduced GDM risk was seen in women regardless of age and parity, and slightly stronger effect was found in women whose age≤30 and women who are nulliparous across the three time periods. …”
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Case based Reasoning Prediksi Waktu Studi Mahasiswa Menggunakan Metode Euclidean Distance dan Normalisasi Min-Max by Henni Endah Wahanani, Made Hanindia Prami Swari, Fawwaz Ali Akbar

“…Abstract One of the reasons for the length of study time for students of the Informatics study program of UPN "Veteran" Jawa Timur is the difficulty of monitoring the progressy, given the large number of students and academics do not have an accurate method to map students who are predicted to experience delays. It is possible to create a system that is able to predict the possibility of student graduation delay through the use of various existing computational methods. …”
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Korelasi Fixation Dan Beban Kognitif pada Pengguna Lansia Dengan Eye-Tracking Pada Aplikasi Komunikasi dan Media Sosial by Jasmine Prigel Palupi Prasojo, Aryo Pinandito

“…Abstract   According to the observations of elderly users who use mobile application for daily activities and the challenges they often face, arising a question to what extent the correlation regarding the cognitive load they experienced from a vision perspective. …”
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Analysis of risk factors of feeding intolerance in ICU patients with enteral nutrition (ICU肠内营养患者喂养不耐受的危险因素分析) by LI Peiyao (李佩瑶), WANG Yue (王玥), ZHANG Yang (张洋), ZHANG Jinjuan (张金娟), JIA Dan (贾丹)

“…Methods Totally 504 ICU patients who received enteral nutrition support were selected and divided into tolerance group (n=331) and intolerance group (n=173) according to the symptoms of feeding intolerance. …”
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Long-term cardiovascular outcomes after percutaneous coronary intervention in patients with systemic sclerosis by Kazutoshi Hirose, Hiroyuki Kiriyama, Shun Minatsuki, Yugo Nagae, Tatsuki Furusawa, Takashi Hiruma, Atsushi Kobayashi, Masataka Sato, Shinnosuke Sawano, Tatsuya Kamon, Hiroki Shinohara, Mizuki Miura, Akihito Saito, Satoshi Kodera, Junichi Ishida, Norifumi Takeda, Hiroyuki Morita, Issei Komuro, Norihiko Takeda

“…Methods: We retrospectively investigated 3,300 patients with CAD who underwent percutaneous coronary intervention (PCI) without prior myocardial infarction or coronary artery revascularization. …”
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Optimizing hip MRI: enhancing image quality and elevating inter-observer consistency using deep learning-powered reconstruction by Yimeng Kang, Wenjing Li, Qingqing Lv, Qiuying Tao, Jieping Sun, Jinghan Dang, Xiaoyu Niu, Zijun Liu, Shujian Li, Zanxia Zhang, Kaiyu Wang, Baohong Wen, Jingliang Cheng, Yong Zhang, Weijian Wang

“…Methods We enrolled a cohort of sixty patients who underwent DL-MRI, conventional MRI, and No-DL MRI examinations to evaluate image quality. …”
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A Pharmacokinetic/Pharmacodynamic Study of Esomeprazole Comparing a Dual Delayed-Release Formulation (YYD601) to a Conventional Formulation Following Multiple Administrations in He... by Lee HW, Kang WY, Park JS, Lee JH, Park JJ, Gwon MR, Yoon YR, Seong SJ

“…Hae Won Lee,1 Woo Youl Kang,2 Ji Seo Park,1 Jae Hwa Lee,1 Jin Ju Park,1 Mi-Ri Gwon,1 Young-Ran Yoon,1 Sook Jin Seong1 1School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, Daegu, 41944, Republic of Korea; 2Clinical Trial Dossier Evaluation Team, Innovative Products Support Department, National Institute of Food and Drug Safety Evaluation, Cheongju, 28159, Republic of KoreaCorrespondence: Young-Ran Yoon, Professor, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, 130 Dongdeok-Ro, Jung-gu, Daegu, 41944, Republic of Korea, Tel +82-53-420-4950, +82-53-420-5218, Email yry@knu.ac.kr Sook Jin Seong, Clinical Associate Professor, School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, 130 Dongduk-Ro, Jung-gu, Daegu, 41944, Republic of Korea, Tel +82-53-200-6351, +82-53-420-5218, Email wintersj@knu.ac.krBackground: YYD601 is a new dual delayed-release formulation of esomeprazole, developed to enhance plasma exposure and prolong the duration of acid suppression.Purpose: This study aimed to evaluate the safety, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of YYD601 20 mg following single and multiple oral administrations in healthy, fasting adult Koreans, and to compare these outcomes to those of the conventional esomeprazole 20 mg capsule.Methods: A randomized, open-label, two-period crossover study was conducted in 28 participants, who were divided into two treatment groups: one group received YYD601 20 mg, and the other received conventional esomeprazole 20 mg, once daily for five consecutive days. …”
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The role of mycobacteremia screening in enhancing non-tuberculous mycobacteria detection in hospitalized persons with HIV by Mengjiao Miao, Hongyan Zhu, Ziyao Liu, Jinjin Yang, Yiting Zhang, Chenyu Ma, Jiamin Qin, Yaling Chen, Hongxia Wei, Wei Chen, Yongfeng Yang, Zhiliang Hu, Zhiliang Hu, Zhiliang Hu

“…To evaluate the prevalence of NTM mycobacteremia and how screening for mycobacteremia assistant with identification of NTM infections, this study retrospectively analyzed 1,136 hospitalized PWH with CD4 counts <200 cells/μL, who underwent mycobacteremia screening at a tertiary hospital in Nanjing, China, between July 2018 and December 2023. …”
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Pengaruh Pemberian Susu Coklat Terhadap Kadar F2Isoprostan pada Siswa di Pusat Pendidikan dan Latihan Olahraga Pelajar (PPLP) Sumatera Barat by Dezi Ilham, Afriwardi , Eti Yerizel

“…This study was an experimental pre and<br />post test control group design to the 36 student athletes, who meet the inclusion and exclusion criteria. The subjects<br />were divided in two groups: the treatment given milk chocolate and white milk is given control, drunk after a routine<br />physical exercise athlete, once a day for 15 days. …”
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Clinical outcome of non-alcoholic fatty liver disease: an 11-year follow-up study by Steven Dooley, Juan Du, Xiaoping Tang, Lan Chen, Jinzhu Jia, Fujun Li, Yanyan Shi, Christoph Meyer, Zhongwei Zhu, Yanming Zhang, Roman Liebe, Keming Hu, Tingting Zhou, Huier Zhang, Hong-Lei Weng, Tong Huang

“…Except one male patient who developed cirrhosis, no patients with NAFLD progressed into severe liver disease.Conclusion Diabetes, hypertension and hyperuricaemia are the main clinical outcomes of NAFLD. …”
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Effect of small boat engine noise on hearing loss of fishermen and efficiency of small boat engine silencer by S. Sinworn, N. Viriyawattana

“…Subsequently, the silencer will be tested on Thai fishermen who are regularly exposed to noise, demonstrating a reduction in engine noise of over 23 decibels A within the frequency range of 100 to 10,000 Hertz.CONCLUSION: The auditory abilities of fishermen are adversely impacted by the intensity and high pitch of the noise emitted by small boat engines. …”
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Exploring the Feasibility of a 5-Week mHealth Intervention to Enhance Physical Activity and an Active, Healthy Lifestyle in Community-Dwelling Older Adults: Mixed Methods Study by Kim Daniels, Sharona Vonck, Jolien Robijns, Kirsten Quadflieg, Jochen Bergs, Annemie Spooren, Dominique Hansen, Bruno Bonnechère

“…Our target group consisted of native Dutch-speaking older adults aged >65 years who were not affected by severe illnesses. Initial assessments and focus groups were conducted in person, whereas the intervention itself was web based. …”
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Klebsiella pneumoniae in stranded California sea lions (Zalophus californianus) of Central California between 2017-2022 by Sydney N. Zotto, Robin C. Dunkin, Juliana D. Limon, Maia S. Smith, Lisabet M. Hortensius, Margaret E. Martinez, Pádraig J. Duignan, Cara Field, Esteban Soto, Dane Whitaker, Carlos Rios, Maurice Byukusenge, Bhushan Jayarao, Suresh V. Kuchipudi, Amy C. Kinsley

“…A similar pattern was observed in beach-cast CSL carcasses by the Long Marine Laboratory (LML) Stranding Network in Santa Cruz, California who had 8 CSLs test positive for K. pneumoniae with an annual incidence rate of 2.0% (1/50) and 10.1% (7/69) in 2021 and 2022, respectively, with no cases reported prior to 2021. …”
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Do preoperative interventions affect patient satisfaction or expectation fulfilment following total hip arthroplasty? A systematic review by April-Rose Matt, Joanne L. Kemp, Andrea B. Mosler, Lucy Salmon, Diogo Almeida Gomes, Alysha De Livera, Erica Hateley, Adam L. Semciw

“…Results: Seven studies were included. Participants who received preoperative interventions were more satisfied (SMD -0.54 [-0.87, −0.21] p ​= ​0.001), and had better function postoperatively when compared to controls (SMD -1.86, 95%CI, −3.11, to 0.61, p ​= ​0.004). …”
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