The real-world efficacy and toxicity of first-line paclitaxel and cisplatin with bevacizumab in platinum-naïve primary stage IVB cervical cancer by Junhwan Kim, Eun-Byul Park, Shin-Wha Lee, Jeong-Yeol Park, Dae-Yeon Kim, Dae-Shik Suh, Jong-Hyeok Kim, Yong-Man Kim, Ju-Hyun Kim

“…Materials and methods: We retrospectively reviewed patients with stage IVB cervical cancer who received paclitaxel-cisplatin-bevacizumab as first-line treatment between July 2015 and December 2021 at Asan Medical Center, Korea. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Methods: 100 pregnant women who completed a 75 g oral glucose tolerance test (OGTT) at 24–28 weeks of gestation were enrolled. …”
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Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations by Ayat Kadhi, Ayat Kadhi, Ayat Kadhi, Edward Eid, Michel J. Massaad, Inaam El-Rassy, Dana Maria Khoury, Yutaka Shimomura, Nelly Rubeiz, Mazen Kurban, Mazen Kurban, Mazen Kurban, Georges Nemer, Georges Nemer

“…Consequently, the immunogenetic foundations underlying these conditions have remained enigmatic.MethodsIn this study, we analyzed the case of a 5-year-old female born to consanguineous parents who presented with concomitant psoriasis and CMC phenotypes. …”
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An Analysis of the Effectiveness and Safety of Upadacitinib in the Treatment of Inflammatory Bowel Disease: A Multicenter Real-World Study by Hongzhen Wu, Tingting Xie, Qiao Yu, Tao Su, Min Zhang, Luying Wu, Xiaoling Wang, Xiang Peng, Min Zhi, Jiayin Yao

“…The study included adult patients aged 18 years or older, diagnosed with UC or CD, who received at least 8 weeks of upadacitinib therapy. …”
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Prevalence and Determinants of Diarrheal Diseases among Under-Five Children in Horo Guduru Wollega Zone, Oromia Region, Western Ethiopia: A Community-Based Cross-Sectional Study by Kefalew Alemayehu, Lemessa Oljira, Melake Demena, Abdi Birhanu, Dasselegn Workineh

“…Diarrhea was significantly associated with poor knowledge of mothers/caretakers on diarrhea prevention methods (AOR: 2.05, 95% CI (1.14, 3.69), being in the age group of 6–11(AOR = 1.546 (1.68, 3.52), and 12–23 months (AOR = 1.485 (1.84, 2.63)), families with poor wealth index (AOR: 2.41, 95% CI (1.29, 4.51)), children who were not vaccinated against measles (AOR: 4.73, 95% CI (2.43, 9.20)), unsafe child feces disposal (AOR = 3.75; 95% CI (1.91, 7.39)), inappropriate liquid waste disposal (AOR = 3.73 (1.94, 7.42)), and having two or more siblings (AOR: 3.11, 95% CI (1.81, 5.35)). …”
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Erratum to ‘Cost differences between autologous and nonautologous cranioplasty implants: A propensity score–matched value driven outcomes analysis’ [World Neurosurgery: X (22C) (20... by Matthew Findlay, Sawyer Z. Bauer, Diwas Gautam, Matthew Holdaway, Robert B. Kim, Walid K. Salah, Spencer Twitchell, Sarah T. Menacho, Gurpreet S. Gandhoke, Ramesh Grandhi

“…Methods: The authors reviewed the hospital billing records over a 12-year period at their institution to identify patients who underwent cranioplasty after decompressive hemicraniectomy for trauma or stroke. …”
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Baseline 18F-FDG PET/CT parameters in predicting the efficacy of immunotherapy in non-small cell lung cancer by Lu Zheng, Lu Zheng, Yanzhu Bian, Yanzhu Bian, Yujing Hu, Congna Tian, Xinchao Zhang, Shuheng Li, Xin Yang, Yanan Qin

“…ObjectiveTo analyse positron emission tomography/ computed tomography (PET/CT) imaging and clinical data from patients with non-small cell lung cancer (NSCLC), to identify characteristics of survival beneficiaries of immune checkpoint inhibitors (ICIs) treatment and to establish a survival prediction model.MethodsA retrospective analysis was conducted on PET/CT imaging and clinical parameters of 155 NSCLC patients who underwent baseline PET/CT examination at the Department of Nuclear Medicine, Hebei General Hospital. …”
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Food for thought: a qualitative assessment of medical trainee and faculty perceptions of nutrition education by Olivia Kunitsky, Mahdi Taye, Karla Feeley, Hugh Johnson, Abigail Glynn, Avery Stivale, Matthew Hamers, Alexis Notarianni, Sireesha Mamillapalli, Gabi Waite, Sonia Lobo

“…Conclusion Participants acknowledged a need for more medical nutrition education to prepare physicians who are equipped to manage the nutritional needs of patients. …”
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Enhancing safety with an AI-empowered assessment and monitoring system for BSL-3 facilities by Yi-Ling Fan, Ching-Han Hsu, Ju-Yu Wu, Ying-Ying Tsai, Wei J. Chen, Min-Shi Lee, Fang-Rong Hsu, Lun-De Liao

“…A deep learning model was trained to detect the presence of essential PPE items, such as clothing, masks, hoods, double-layer gloves, shoe covers, and respirators, ensuring adherence to World Health Organization (WHO) standards. The internal laboratory management system used a deep learning model to delineate alert zones and monitor compliance with the imposed safety protocols. …”
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Association between exposure to ambient air pollutants and metabolic syndrome in the vicinity of the Taklamakan Desert by Zhe Wang, Weidong Ji, Yushan Wang, Lin Li, Kai Wang, Hongze Liu, Yining Yang, Yi Zhou

“…Conclusions: There is an observed association between long-term exposure to air pollution and a heightened risk of MetS, particularly in men, younger individuals, those who are physically inactive, and smokers.…”
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Work–health–personal life conflicts in naive patients with chronic hepatitis B receiving initial treatment in China: a qualitative study by Li Zhang, Ying Chen, Ying Li, Hongmei Wang, Lin Zhu, Xiaoyang Lu, Yingjing Zheng, Donald Patrick, Fengjiao Xu, Mengna Song, Xiao Cheng, Boyan Chen

“…Then, researchers chose one tertiary hospital from each city as the study site, so a total of six tertiary hospitals were involved.Participants We recruited 32 patients with CHB (59.38% male) who had just started antiviral therapy for no more than three months. …”
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Primary results from the Japanese Heart Failure and Sudden Cardiac Death Prevention Trial (HINODE) by Kazutaka Aonuma, Kenji Ando, Kengo Kusano, Toru Asai, Koichi Inoue, Yukihiro Inamura, Takanori Ikeda, Takeshi Mitsuhashi, Toyoaki Murohara, Nobuhiro Nishii, Akihiko Nogami, Wataru Shimizu, Caroline Beaudoint, Torri Simon, Torsten Kayser, Hussin Azlan, Ngarmukos Tachapong, Joseph Yat‐Sun Chan, Valentina Kutyifa, Yasushi Sakata, For the HINODE Investigators

“…Conclusions The mortality and VA event rates of landmark trials are applicable to patients with primary prevention in Japan. Patients who did not receive guideline‐indicated CRT devices had poor outcomes.…”
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Levodopa Challenge Test Predicts STN-DBS Outcomes in Various Parkinson’s Disease Motor Subtypes: A More Accurate Judgment by Zijian Zheng, Zixiao Yin, Bohan Zhang, Houyou Fan, Dan Liu, Yuancheng Zhou, Jian Duan, Dongwei Zhou, Xi Wu, Guohui Lu

“…We retrospectively collected data from 147 patients who received the Unified Parkinson’s Disease Rating Scale- (UPDRS-) III and the Parkinson’s Disease Questionnaire- (PDQ-) 39 evaluation. …”
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Effect of Vocational Rehabilitation Training Camp on Patients with Spinal Cord Injury Returning to Society by Lingjuan RAO, Li DAI, Li CHEN, Xiaoling LI, Jichao XIONG, Qingjun YANG, Huazhong YANG, Jinlong CUI

“…Objectives:To investigate the therapeutic effect of vocational rehabilitation training camp on patients with spinal cord injury (SCI) returning to society.Methods:A total of 34 patients with spinal cord injury who were hospitalized and received rehabilitation treatments in Xiangya Boai Rehabilitation Hospital from October 2017 to October 2019 were recruited and randomly divided into control group (16 cases) and observation group (18 cases) according to the random number table method. …”
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Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world compar... by Rohan Khera, Yuan Lu, Harlan M Krumholz, Martijn J Schuemie, Ruijun Chen, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets

“…LEGEND-T2DM will identify all adult, patients with T2DM who newly initiate a traditionally second-line T2DM agent. …”
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NEWCOMBO PROBLEMA IR AMERIKIETIŠKAS KLAUSIMAS by Zenonas Norkus

“…So the actor's rationality or its absence is the common cause of actor's "bad news, small benefit" choices and of Predictor's predictions who is discriminating against the bright actors (including all causal decision theorists, of course) by providing for them no opportunity to avoid undesirable state. …”
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Risk factors for Clostridioides difficile infection among patients diagnosed with inflammatory intestinal and rheumatological diseases in the biologic era by Helena Martínez-Lozano, Paula Saralegui-Gonzalez, Elena Reigadas, Pablo Ramón Fueyo-Peláez, Aurea García-García, José Miranda-Bautista, Luis Alcalá, Juan Carlos Nieto, María Elena Lobato-Matilla, Ignacio Marín-Jiménez, Patricia Muñoz, Luis Menchén

“…Although the subgroup of IBD patients receiving biologics showed a higher incidence of CDI compared to unexposed IBD patients, biologic therapy was not an independent risk factor for CDI in the logistic regression model; nevertheless, patients who received 3 or more biologic agents had a significantly higher risk for CDI (OR: 3.09, CI 95% 1.13–8.47, p = 0.028). …”
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Hubungan Tingkat Kemandirian dalam Melakukan Aktivitas Kehidupan Sehari-Hari dan Status Gizi pada Usia Lanjut di Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin by Afifah Alfyanita, Rose Dinda Martini, Husnil Kadri

“…The instruments of this research were Barthel ADL and Mini Nutritional Assessment (MNA). 66 samples were taken from all the inhabitants of Panti Sosial Tresna Werdha Sabai Nan Aluih Sicincin who fulfill the inclusion criteria. The results of the level of independence and nutritional status were analyzed using chi-square test, with a degree of confidence of 95%. …”
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Perbedaan Kadar Superokside Dismutase pada Remaja dengan Dismenore Primer dan Tanpa Dismenore Primer by Yanti ., Ermawati ., Eliza Anas

“…The result obtained by the average levels of SOD adolescents who experienced dysmenorrea is 36,76u/ml, with a value of p>0,05 (0,345). …”
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An oral microbiota-based deep neural network model for risk stratification and prognosis prediction in gastric cancer by Xue-Feng Gao, Can-Gui Zhang, Kun Huang, Xiao-Lin Zhao, Ying-Qiao Liu, Zi-Kai Wang, Rong-Rong Ren, Geng-Hui Mai, Ke-Ren Yang, Ye Chen

“…The identified bacterial markers were used to construct a Deep Neural Network (DNN) model, a Random Forest (RF) model, and a Support Vector Machine (SVM) model for predicting GC prognosis.Results GC patients with <3 years of survival showed a higher abundance of Aggregatibacter and diminished abundances of Filifactor and Moryella than those who survived ≥3 years. The Boruta algorithm unearthed Leptotrichia as another significant marker for GC prognosis. …”
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