Clostridium difficile-associated disease in versatile hospital patient population and risk factors for its development by Ya. N. Yarushina, G. B. Kolotova, V. A. Rudnov, V. A. Bagin

“…Retrospective analysis of 131 case records of the in-patients of Yekaterinburg City Hospital No. 40 for the year 2014 who developed diarrhea during antibacterial therapy was carried out. …”
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Modified Endothelial Activation and Stress Index: A New Predictor for Survival Outcomes in Classical Hodgkin Lymphoma Treated with Doxorubicin-Bleomycin-Vinblastine-Dacarbazine-Bas... by Fazıl Çağrı Hunutlu, Hikmet Öztop, Vildan Gürsoy, Tuba Ersal, Ezel Elgün, Şeyma Yavuz, Selin İldemir Ekizoğlu, Azim Ali Ekizoğlu, Vildan Özkocaman, Fahir Özkalemkaş

“…<b>Methods:</b> Data from 206 patients who underwent positron emission tomography (PET)-guided doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) therapy for cHL between January 2007 and November 2023 were retrospectively analyzed. …”
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Do you know your PSMA-tracer? Variability in the biodistribution of different PSMA ligands and its potential impact on defining PSMA-positivity prior to PSMA-targeted therapy by Jan Heilinger, Katrin Sabine Roth, Henning Weis, Antonis Fink, Jasmin Weindler, Felix Dietlein, Philipp Krapf, Klaus Schomäcker, Bernd Neumaier, Markus Dietlein, Alexander Drzezga, Carsten Kobe

“…In this study, we aimed to compare tracer uptake intraindividually in various reference regions including liver, parotid gland and spleen as well as the respective tumor-to-background ratios (TBR) of different 18F-labeled PSMA ligands to today’s standard radiopharmaceutical 68Ga-PSMA-11 in a series of patients with biochemical recurrence of prostate cancer who underwent a dual PSMA-PET examination as part of an individualized diagnostic approach. …”
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Gender differences in early posttraumatic stress disorder symptoms: a network analysis by Line Rønning, Rachel L. Zelkowitz, Marilyn L. Piccirillo, Jianlin Liu, Jordan L. Thomas, Jessy Guler, J. Joana Kyei, Chris M. Hoeboer, Jeanet F. Karchoud, Miranda Olff, Anke B. Witteveen, Mirjam van Zuiden

“…Background: Despite known gender/sex differences in the prevalence of posttraumatic stress disorder (PTSD), potential differences in the associations among PTSD symptoms between men and women in the early post-trauma period are not well-characterized.Objective: This study utilized network analysis to assess potential differences in the associations among PTSD symptom clusters between men and women during the early post-trauma period.Method: We included n = 475 participants (57.5% self-identified women) who recently (≤2 months) experienced an interpersonal or motor vehicle potential traumatic event in the Netherlands. …”
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Relationship Between RNF213 p.R4810K and Echocardiographic Findings in Patients with Cerebrovascular Diseases: A Multicenter Prospective Cohort Study by Kotaro Noda, Yorito Hattori, Tatsuya Nishii, Hiroki Horinouchi, Yuriko Nakaoku, Soshiro Ogata, Yasunobu Inagaki, Ryotaro Asano, Takeshi Yoshimoto, Kunihiro Nishimura, Takeshi Ogo, Yoshikazu Nakaoka, Masafumi Ihara

“…Methods and Results We investigated patients registered in the National Cerebral and Cardiovascular Center Genome Registry between May 2017 and August 2021 who underwent echocardiography. All patients had cerebrovascular diseases. …”
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Measured Resection as Gap Balance Method in Mobile‐Bearing Medial Unicompartmental Knee Arthroplasty: A Randomized Controlled Trial by Qian Liu, Jianhua Ren, Wenhui Zhang, Tangzhao Liang, Zhe Wang, Siwei Xie, Yuhang Li, Jianfeng Hou, Kun Wang, Ronghan He

“…Methods This prospective study included 49 consecutive patients (52 knees) who underwent MB‐UKA from February 1, 2023, to September 1, 2023. …”
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Prevalence and determinants of full vaccination coverage according to the national schedule among children aged 12–35 months in Ghana by Berhan Tekeba, Tadesse Tarik Tamir, Alebachew Ferede Zegeye

“…Women having an ANC visit were 40% more likely (AOR = 1.40, 95% CI 1.07–1.83), women involved in healthcare decision-making were 35% more likely (AOR = 1.35, 95% CI 1.05–1.75), Women who deliver in a health facility were 1.91 times more likely (AOR = 1.91, 95% CI 1.36–2.66), and communities with high media exposure were 47% more likely (AOR = 1.47, 95% CI 1.06–2.05) to achieve full vaccination coverage as compared to their counterparts. …”
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Clinical Profile and Outcome in Patients with Coronary Slow Flow Phenomenon by Xiaogang Zhu, Hua Shen, Fei Gao, Sijing Wu, Qian Ma, Shuo Jia, Ziwei Zhao, Shan Tong, Zhihao Zhang, Yujie Zhou

“…We investigated a cohort of 429 patients who fulfilled the criteria for CSFP to explore the clinical feature, outcome, and risk factor of prognosis. …”
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Prevalence, Pattern and Factors Associated with Developmental Delay amongst Under-5 Children in Nigeria: Evidence from Multiple Indicator Cluster Survey 2011–2017 by Olayide Olubunmi Olabumuyi, Obioma Chukwudi Uchendu, Pauline Aruoture Green

“…This study comprised a weighted sample of 17,373 under-5 children who had complete data from both survey rounds on characteristics deemed significant for the study. …”
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A Real World Report on Intravenous High-Dose and Non-High-Dose Proton-Pump Inhibitors Therapy in Patients with Endoscopically Treated High-Risk Peptic Ulcer Bleeding by Lung-Sheng Lu, Sheng-Chieh Lin, Chung-Mou Kuo, Wei-Chen Tai, Po-Lin Tseng, Kuo-Chin Chang, Chung-Huang Kuo, Seng-Kee Chuah

“…A total of 220 subjects who received high-dose and non-high-dose pantoprazole for confirmed acute PU bleeding that were successfully treated endoscopically were enrolled. …”
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From Clinical Trial Evidence to Clinical Guidelines: Perspectives on REWIND from Clinicians in the Gulf and Levant Region by Talal Ashour, Sami Azar, Akram Echtay, Muhammad Farooqi, Tarek Fiad, Mohamed Hassanein, Ahmed Hassoun, Abdul Jabbar, Amin Jayyousi, Kari Ranta, Hani Sabbour, Fatih Tangi, Ibrahim Turfanda

“…Background: Current guidelines recommend that glucagon-like peptide-1 receptor agonists (GLP-1 RAs) with proven cardiovascular benefit should be considered for first-line therapy in patients with type 2 diabetes (T2D) who have/are at high risk of atherosclerotic cardiovascular disease (CVD). …”
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Staged angioplasty using a full-length balloon catheter to achieve maturation of arteriovenous fistulas by Chung Won Lee, Chang Ho Jeon, Sung Woon Chung, Chung Won Lee, Up Huh, Jongwon Kim, Hyuncheol Jeong

“…METHODS: This study included patients who underwent AVF surgery using an autogenous vein between February 2020 and June 2021 and received staged angioplasty with a full-length balloon catheter. …”
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The analgesic effects of quadratus lumborum block versus caudal block for pediatric patients undergoing abdominal surgery: a systematic review and meta-analysis by Yu Zhu, Jin Wu, Shenglong Qu, Peng Jiang, Chetan Bohara, Chetan Bohara, Yi Li

“…The primary endpoint was the rate of postoperative rescue analgesia, defined as the proportion of patients who returned to acetaminophen, ibuprofen, and other analgesics when the pain score was greater than the protocol preset value within 24 h after surgery. …”
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Internalizing and externalizing symptoms in individuals with neurofibromatosis type 1: a systematic review and meta-analysis by Dan Liu, Liyan Yu, Xian Wu, Julia Moreira, Benjamin Felipe Mujica, Elora Shelly Mukhopadhyay, Angelena Novotney, André B. Rietman, Yang Hou

“…Studies that included more participants with NF1 who had ADHD or a lower verbal IQ reported greater group disparities in total internalizing symptoms or aggression. …”
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A Novel Telehealth Exercise Program Designed for Rural Survivors of Cancer With Cancer-Related Fatigue: Single-Arm Feasibility Trial by Ryan J Marker, Andrew J Kittelson, Jared J Scorsone, Ian A Moran, John C Quindry, Heather J Leach

“…Eligible participants were adult survivors of any cancer diagnosis who had completed treatment with curative intent in the past 12 months or had no planned changes in treatment for the duration of the study, lived in a rural area, and were currently experiencing CRF. …”
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Correlation analysis between preoperative odontoid incidence and clinical outcomes 2 years after anterior cervical discectomy and fusion by Yan Gong, Hao Liu, Yanchi Gan, Jiahui He, Zelin Zhou, Hang Zhuo, Yu Liu, De Liang, Hui Ren, Xiaobing Jiang, Zhaojun Cheng

“…Methods A retrospective analysis of the clinical data of 87 patients with CSM who underwent ACDF surgery from January 2018 to December 2023 was conducted. …”
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Topical chlorhexidine 0.2% versus topical natamycin 5% for fungal keratitis in Nepal: rationale and design of a randomised controlled non-inferiority trial by Victor Hu, David Macleod, Helen Anne Weiss, Matthew J Burton, Simon Arunga, Astrid Leck, Sanjay Kumar Singh, Jeremy John Hoffman, Reena Yadav, Sandip Das Sanyam, Pankaj Chaudhary, Abhishek Roshan, Einoti Matayan

“…Secondary outcomes include epithelial healing time, scar/infiltrate size, ulcer depth, hypopyon size, perforation and/or therapeutic penetrating keratoplasty (corneal transplant), positive reculture rate (day 7) and quality of life (EuroQol-5 dimensions, WHO/PBD-VF20, WHOQOL-BREF).Ethics and dissemination The Nepal Health Research Council, the Nepal Department of Drug Administration and the London School of Hygiene and Tropical Medicine ethics committee have approved the trial. …”
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Efficacy of an intervention to increase therapeutic adherence in patients with secondary prevention for cardiovascular disease: a study protocol for a randomized controlled trial by Francisco Manuel Lidón-Muñoz, José Antonio Quesada, José Antonio Quesada, José Antonio Quesada, Vicente Francisco Gil-Guillén, Vicente Francisco Gil-Guillén, Vicente Francisco Gil-Guillén, Domingo Orozco-Beltrán, Domingo Orozco-Beltrán, Domingo Orozco-Beltrán

“…Furthermore, non-adherence is more pronounced in primary care.ObjectiveBased on our hypothesis that in patients undergoing cardiovascular secondary prevention, an intervention grounded in the application of the Chronic Care Model improves adherence to the three preventive drugs, this study aims to evaluate the efficacy of a health education intervention, which implements this model, to increase adherence in patients with cardiovascular disease.MethodsAn open-label randomized controlled trial will be conducted, selecting patients who meet inclusion criteria through consecutive non-probability sampling. …”
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Rates of Multidrug-Resistant Gram-Negative Bacterial Infections in Hospitalized Non-Immunocompromised Pediatric Patients: A 9-Year Retrospective Study at a Lebanese Tertiary Medica... by Zakhour R, Khafaja S, Korman R, Boutros CF, El Zein Z, Chmaisse A, Haj M, Haddara A, El-Houry Z, Jbahi M, Chamseddine S, Bou Karroum S, Al Oweini D, Youssef YS, Youssef N, Nasser M, Fayad D, Abi Farraj F, El Nakib C, Isaac I, Lteif M, Araj GF, Dbaibo GS

“…Ramia Zakhour,1,2,&ast; Sarah Khafaja,1,2,&ast; Rawan Korman,1,&ast; Celina F Boutros,1 Zeinab El Zein,1– 3 Ahmad Chmaisse,1 Magda Haj,1 Amani Haddara,1 Zeina El-Houry,1 Malak Jbahi,1 Sarah Chamseddine,1 Samer Bou Karroum,1 Dana Al Oweini,1 Yolla Salama Youssef,1 Nour Youssef,1,2 Mayse Nasser,1 Danielle Fayad,1 Farida Abi Farraj,1 Clara El Nakib,1 Imad Isaac,1 Mireille Lteif,1 George F Araj,1,4 Ghassan S Dbaibo1– 3 1Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon; 2Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon; 3Division of Pediatric Infectious Diseases, Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon; 4Clinical Microbiology Laboratory, Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon&ast;These authors contributed equally to this workCorrespondence: Ghassan S Dbaibo, Center for Infectious Diseases Research (CIDR), Division of Pediatric Infectious Diseases, Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, 1107, Lebanon, Email gdbaibo@aub.edu.lbIntroduction: Multidrug resistant (MDR) Gram-negative bacterial infections are considered a major public health threat. …”
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Tomographic features of lung damage associate with D-Dimer levels and further clinical outcome in patients with acute respiratory distress syndrome due to COVID-19 by Juan Antonio Suárez-Cuenca, José Fernando Flores-Zaleta, Leslie Andrea Corona-Rojas, Pablo Guzmán-Rullán, Luis Alfonso Camacho-Barajas, Uzziel Aguilera-Ontiveros, Alberto Melchor-López, Alejandro González-Mora, Perla Marlene Guzmán-Ramírez, Janicia Rodríguez-Solis

“…Patients diagnosed with ARDS due to COVID-19, without previous lung damage, clotting disorder and/or anticoagulants use, who were attended at the Intensive Care Unit and Internal Medicine Department from March to June 2020. …”
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