Clinical outcomes of chimeric antigen receptor T-cell therapy following autologous hematopoietic stem cell transplantation in 38 patients with refractory/relapsed primary or second... by Jiaying Wu, Wanying Liu, Yang Cao, Yang Yang, Zhen Shang, Mi Zhou, Yicheng Zhang, Fankai Meng, Xiaojian Zhu, Yi Xiao

“…Methods The cohort in this retrospective study consisted of 38 patients with r/r CNSL who received CAR T-cell therapy following ASCT at our center between January 2019 and April 2024. …”
Get full text

Sex differences in intracranial plaque burden in patients with type 2 diabetes mellitus with acute ischemic cerebrovascular disease: a pilot study based on high-resolution MRI by Xuejiao Yan, Ling Li, Jie Gao, Lihui Wang, Kai Ai, Xiaoyan Lei, Min Tang, Xiaoling Zhang, Dongsheng Zhang

“…This study attempts to explore possible associations between sex, treatment, and the burden of intracranial atherosclerosis (ICAS) in patients with T2DM who have experienced an acute ischemic cerebrovascular disease.MethodsWe focused on patients with T2DM with acute ischemic stroke or transient ischemic attack due to intracranial atherosclerotic stenosis. …”
Get full text

Digital Mindfulness Training for Burnout Reduction in Physicians: Clinician-Driven Approach by Lia Antico, Judson Brewer

“…Mindfulness training (MT) has proven effective in reducing burnout; however, its time-consuming requirements often pose challenges for physicians who are already struggling with their busy schedules. …”
Get full text

Clinical Characteristics of COVID-19 in Neonates and Infants Younger Than 3 Months by Fatemeh Varshoei, Mohammad Sadegh Rezai, Roya Farhadi, Azin Hajialibeig, Saeid Mohammadi, Masoud Moradi, Fatemeh Hosseinzadeh

“…Moreover, in infants under 3 months who are hospitalized due to confirmed COVID-19 and do not have sepsis symptoms, there is no indication of a lumbar puncture (LP) procedure.…”
Get full text

Noninsulin Antidiabetic Drugs for Patients with Type 2 Diabetes Mellitus: Are We Respecting Their Contraindications? by Irene Ruiz-Tamayo, Josep Franch-Nadal, Manel Mata-Cases, Dídac Mauricio, Xavier Cos, Antonio Rodriguez-Poncelas, Joan Barrot, Gabriel Coll-de-Tuero, Xavier Mundet-Tudurí

“…Electronic medical records were retrieved from all T2DM subjects who attended primary care centers pertaining to the Catalan Health Institute in Catalonia in 2013 and were pharmacologically treated with any NIAD alone or in combination. …”
Get full text

The Application of Three-dimensional Shear Wave Elastography in the Detection of Inguinal Lymph Node Metastasis in Gynecological Malignancies by Yuping Shen, Jiulong Dai, Jiami Li, Man Lu

“…Methods: This retrospective study evaluated 120 ILNs from patients with gynecological cancers who underwent conventional ultrasound (US), two-dimensional shear wave elastography (2D-SWE), and multiplanar 3D-SWE. …”
Get full text

Proportion, quality of life and factors associated with perinatal urinary incontinence among pregnant women attending at Muhimbili national hospital by Geofrey P. Chiloleti, Fransia Arda Mushi, Aboud Muhsin, Ally Mwanga

“…Overall, among the participants who had PUI, quality of life (QoL) was moderately affected in 31 (52.5%) participants, followed by 17 (28.8%) whose QoL was slightly affected, 10 (16.9%) whose QoL was poor, and only 1 (1.7%) whose quality of life was very poor. …”
Get full text

Determining the Prevalence of Pain in Adult Patients Hospitalized in a University Hospital in Western Türkiye: An Observational Point Prevalence Study by Erkan Özduran, Volkan Hancı, Yüksel Erkin, Ali Avcı, Ali Emircan Ilgınlı, Burakcan Budakın, Deniz Metin Açıkgöz, Gökhan Gökmen, Mehmet Fatih Erfidan, Muhammed Can Feda Dinç, Rana Elif Aydoğdu, Soner Demircan, Tunahan Birkol

“…This study aimed to investigate the prevalence and associated factors of pain in adult patients hospitalized in a university hospital in western Türkiye.Material and method: After obtaining ethical committee approval, this cross-sectional study investigated the prevalence of pain and associated factors in hospitalized patients who met the inclusion criteria using a face-to-face survey method between May 1-31, 2022. …”
Get full text

Risk of All-Cause Mortality in US Adults With Preserved Ratio Impaired Spirometry: An Observational Study by Xiao S, Ou J, Qiu W, Ye C, Li N, Chen S, Lai Y, Deng Z, Wu F, Shen Y

“…Participants aged 20– 79 years at baseline and who underwent spirometry were included. Normal spirometry was defined as a prebronchodilator FEV1/FVC≥ 0.70 and FEV1≥ 80% predicted. …”
Get full text

Mechanical and Pharmacological Revascularization Strategies for Prevention of Microvascular Dysfunction in ST-Segment Elevation Myocardial Infarction: Analysis from Index of Microc... by Ji-Hun Jang, Man-Jong Lee, Kyu-Yong Ko, Jin-Hee Park, Yong-Soo Baek, Kwon Sung-Woo, Sung-Hee Shin, Seong-Ill Woo, Dae-Hyeok Kim, Young Ju Suh, Jun Kwan, Sang-Don Park

“…Methods. Patients with STEMI who underwent primary percutaneous coronary intervention (PCI) were enrolled. …”
Get full text

Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis. by Tara Cain, Jacinta Brinsley, Hunter Bennett, Max Nelson, Carol Maher, Ben Singh

“…While meta-analysis showed no significant effects on immune function immediately (SMD: -0.16 [95% CI: -0.82, 0.51], p >  0.05) or 1 hour (SMD: -0.18 [95% CI: -1.09, 0.74], p >  0.05) post-CWI, narrative synthesis suggested longer-term benefits, including a 29% reduction in sickness absence among participants who took cold showers. Improvements were also observed in sleep quality and quality of life, but not mood.…”
Get full text

Comparative effectiveness of urine drug screening strategies alongside opioid agonist treatment in British Columbia, Canada: a population-based observational study protocol by Malcolm Maclure, M Eugenia Socías, Evan Wood, Paul Gustafson, Robert W Platt, Bohdan Nosyk, Jeong Eun Min, Micah Piske, Julie Bruneau, U Siebert, P Todd Korthuis, Paxton Bach, B Carolina Guerra-Alejos, Megan Kurz, Laura M Dale, X Joan Hu, Kyle Kampman, Tom Loughin

“…Our objective is to determine the safety and comparative effectiveness of alternative UDT monitoring strategies as observed in clinical practice among OAT clients in British Columbia, Canada from 2010 to 2020.Methods and analysis We propose a population-level retrospective cohort study of all individuals 18 years of age or older who initiated OAT from 1 January 2010 to 17 March 2020. …”
Get full text

Comparison of IMO vifa24plus(1-2) and Humphrey Field Analyzer 24-2 by Takagi Y, Asano R, Yamashita K, Sakai Y, Yokoyama S, Ichikawa K, Ichikawa K

“…Yuki Takagi,1,2 Ryo Asano,1,3 Kanna Yamashita,2 Yukihiro Sakai,2 Sho Yokoyama,1 Kei Ichikawa,2 Kazuo Ichikawa2 1Department of Ophthalmology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Aichi, Japan; 2Chukyo Eye Clinic, Nagoya, Aichi, Japan; 3Asano Eye Clinic, Nagoya, Aichi, JapanCorrespondence: Yuki Takagi, Department of Ophthalmology, Japan Community Healthcare Organization Chukyo Hospital, 1-1-10 Sanjo Minami-ku, Nagoya, Aichi, Japan, Tel +81-52-691-7151, Fax +81-52-692-5220, Email ytakagi@sanjogroup.jpPurpose: This study aimed to compare the results of the IMO vifa 24plus(1– 2) and HFA 24– 2 visual field tests.Patients and Methods: We included 52 patients (104 eyes) with glaucoma who visited Chukyo Eye Clinic between June 2023 and March 2024. …”
Get full text

Impact of perineural tumor spread in head and neck adenoid cystic carcinoma for carbon-ion radiotherapy by Atsushi Musha, Nobuteru Kubo, Hidemasa Kawamura, Naoko Okano, Masahiro Onishi, Takeru Ohtaka, Midori Tamura, Osamu Nikkuni, Yuichi Tomidokoro, Satoshi Yokoo, Kazuaki Chikamatsu, Tatsuya Ohno

“…Materials and methods: In this retrospective study, we included 74 patients diagnosed with HN-ACC who underwent C-ion RT between June 2010 and July 2022. …”
Get full text

Cytokine Kinetics in Febrile Neutropenic Children: Insights on the Usefulness as Sepsis Biomarkers, Influence of Filgrastim, and Behavior of the IL-23/IL-17 Pathway by Orlei Ribeiro de Araujo, Reinaldo Salomão, Milena Karina Coló Brunialti, Dafne Cardoso Bourguignon da Silva, Andreza Almeida Senerchia, Fabianne Altruda de Moraes Costa Carlesse, Antonio Sergio Petrilli

“…On day 1, IL-6, IL-8, and IL-10 appeared upregulated in patients who received filgrastim. Only IL-6, IL-8, IL-10, and procalcitonin were useful as discriminators of sepsis. …”
Get full text

Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…The success rate among CLD patients was 66.6% and those who had no co-morbidities was 65.6 %. Similarly, the complication rate in CLD patients was 33.34% whereas in patients with no co-morbidities it was 31.25%. …”
Get full text

LIMITAÇÕES DAS LEITURAS DE TEMPERATURA TEMPORAL (TESTA) COMO MÉTODO DE TRIAGEM PARA COVID-19 by Luis Fernando Aragón-Vargas

“…., 2020; Sainati & Biffi, 2020); esse tipo de triagem também é normalmente observado nas reportagens de TV antes da entrada de pessoas ser permitida em clínicas de saúde, restaurantes, locais de trabalho ou transporte público.Finalmente, a triagem para febre faz parte das recomendações da Organização Mundial de Saúde para o manejo de viajantes doentes nas fronteiras internacionais (World Health Organization [WHO], 2020). Aparentemente, o método de escolha para esse rastreamento de febre é medir a temperatura da artéria temporal (testa) com diferentes dispositivos infravermelhos sem contato, que fornecem uma leitura prática, razoavelmente segura e rápida. …”
Get full text

Impact of Helicobacter pylori infection on neoadjuvant chemotherapy in locally advanced gastric cancer: a retrospective analysis by Bin Zhong, Zhizhong Xiong, Jiabo Zheng, Saddam Ahmed Mohamed, Jiachen Sun, Dayin Huang, Zijian Deng, Jianping Guo, Junsheng Peng, Huashe Wang, Lei Lian

“…Methods This retrospective study utilized data from patients with LAGC who underwent neoadjuvant chemotherapy and surgical treatment at the Sixth Affiliated Hospital of Sun Yat-sen University from January 1, 2010, to January 31, 2021. …”
Get full text

Validity, reliability and clinical utility of ASSIST-Y in assessing risk of substance-related harm and dependence in Spanish male adolescents by Núria Ibáñez-Martínez, Matthew William Richard Stevens, Núria Civit-Bel, Noemí Moreno-Ferrer, Sandra Lopez-Ferré, Ana Olivares-Casado, Juame Claramunt-Mendoza, Chris Holmwood, Robert Ali

“…Conclusions As a screening tool, the purpose of ASSIST-Y is designed to help identify adolescents who may be at-risk of substance-related harm. While the instrument was found to be valid and reliable in identifying risky use across a variety of substances, further research is needed to validate the instrument in other population groups, and for other substances. …”
Get full text

Evaluating the use of coronary artery calcium scoring as a tool for coronary artery disease (CAD) risk stratification and its association with coronary stenosis and CAD risk factor... by Afrose Liaquat, Ameerdad Khan, Saeed Ullah Shah, Hania Iqbal, Safa Iqbal, Atif Iqbal Rana, Habib Ur Rahman

“…The aim of our study is to investigate the use of coronary artery calcium scoring (CACS) as a tool for CAD risk stratification through evaluation of its correlation with the degree of coronary stenosis and its association with conventional cardiovascular risk factors in asymptomatic patients.Design Single-centre, retrospective, cross-sectional study.Setting The study was conducted at a tertiary centre (Shifa International Hospital) in Islamabad, Pakistan, through review of medical records of patients who underwent coronary CT between the years 2016 and 2020.Participants A total of 1014 patients were included in the study. …”
Get full text