Malignant biliary obstruction treated with preoperative endoscopic ultrasound-guided hepaticogastrostomy: A case report by Taira Kuroda, Hideki Miyata, Yuka Kimura, Ayaka Nakamura, Takuya Matsuda, Kana Matsuoka, Mai Fukumoto, Kazuya Murakawa, Taisei Murakami, Hirofumi Izumoto, Kei Onishi, Shogo Kitahata, Kozue Kanemitsu-Okada, Tomoe Kawamura, Fujimasa Tada, Eiji Tsubouchi, Jun Hanaoka, Atsushi Hiraoka, Tomoyuki Ninomiya

“…We present the case of a 76-year-old man who underwent preoperative endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) for obstructive jaundice caused by pancreatic head cancer. …”
Get full text

Inherited metabolic diseases are a potent risk factor for cytomegalovirus infection in pediatric living donor liver transplantation by Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Toshio Horiuchi, Takahiko Omameuda, Kiichiro Takadra, Ryosuke Akimoto, Yasuharu Onishi, Yasunaru Sakuma, Koichi Mizuta

“…CMV serostatus is a well-established risk factor for postoperative CMV infection, with CMV seronegative recipients who receive organs from seropositive donors (D+/R−) being at the highest risk. …”
Get full text

Efficacy and Safety of Antimalarial as Repurposing Drug for COVID-19 Following Retraction of Chloroquine and Hydroxychloroquine by Latarissa IR, Khairinisa MA, Iftinan GN, Meiliana A, Sormin IP, Barliana MI, Lestari K

“…This made World Health Organization (WHO) ban the usage for COVID-19 patients. In this context, there is a need to explore other antimalarial drugs as potential therapies for COVID-19. …”
Get full text

Do non-mammary conditions influence patients’ cosmetic perception after breast conserving surgery? by Idam de Oliveira-Junior, Idam de Oliveira-Junior, Fabíola Cristina Brandini da Silva, Fabíola Cristina Brandini da Silva, Almir José Sarri, René Aloísio da Costa Vieira, René Aloísio da Costa Vieira

“…However, some BCS patients consider the cosmetic result to be unsatisfactory, which may affect QOL.Material and methodsThis prospective, cross-sectional study included patients who underwent BCS. The patients answered the European Organization for Research and Treatment of Cancer Quality of Life questionnaire (EORTC QLQ) - C30, EORTC QLQ-BR23 and Breast Cancer Treatment Outcome Scale (BCTOS) questionnaires, underwent cosmetic breast self-assessment and had their breasts photographed. …”
Get full text

Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation by Lin Cheng, Sheng Xu, Yu‐feng Wang, Sheng‐wei Li, Bin Li, Xiao‐Guang Li

“…Risk stratification indicated that patients with persistent ctDNA had worse clinical outcomes compared to those who never had detectable ctDNA (p = 0.004). Conclusion Our findings suggest that ctDNA monitoring can assist in predicting clinical outcomes in stage I NSCLC treated with microwave ablation. …”
Get full text

Triglyceride glucose index–body mass index as a predictor of coronary artery disease severity in patients with H-type hypertension across different glucose metabolic states by Lian Wang, Zijin Li, Rui Qiu, Li Luo, Xisheng Yan

“…Methods This retrospective cohort study included 1537 hypertensive patients who underwent coronary angiography. The TyG-BMI was categorized into tertiles and analyzed using logistic regression models and restricted cubic spline (RCS) models to assess its association with multi-vessel CAD. …”
Get full text

Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm by Aiji Sakamoto, Masaaki Kawashiri, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Masakazu Yamagishi

“…From 10 patients (9 males and 1 female; age, 68.5±2.4) who underwent vascular surgery for AAA, we obtained AAA and adjacent control tissues. …”
Get full text

Radiotherapy for Oligometastases and Oligo-Recurrence of Bone in Prostate Cancer by Ken-ichi Tabata, Yuzuru Niibe, Takefumi Satoh, Hideyasu Tsumura, Masaomi Ikeda, Satoru Minamida, Tetsuo Fujita, Daisuke Ishii, Masatsugu Iwamura, Kazushige Hayakawa, Shiro Baba

“…Fourteen out of 16 patients (87.5%) who had pain were improved 1 month after radiotherapy. …”
Get full text

Growth Arrest Specific Gene 6 Protein Concentration in Cerebrospinal Fluid Correlates with Relapse Severity in Multiple Sclerosis by P. P. Sainaghi, L. Collimedaglia, F. Alciato, R. Molinari, D. Sola, E. Ranza, P. Naldi, F. Monaco, M. Leone, M. Pirisi, G. C. Avanzi

“…Methods. Sixty-five patients who underwent a spinal tap during relapse of relapsing/remitting multiple sclerosis (RR-MS)(McDonald-criteria) were studied. …”
Get full text

Assessment of Geriatric Problems and Risk Factors for Delirium in Surgical Medicine: Protocol for Multidisciplinary Prospective Clinical Study by Henriette Louise Möllmann, Eman Alhammadi, Soufian Boulghoudan, Julian Kuhlmann, Anica Mevissen, Philipp Olbrich, Louisa Rahm, Helmut Frohnhofen

“…MethodsWe performed both pre- and postoperative assessments in patients of 4 different surgical departments who are older than 70 years. Patient-validated screening instruments will be used to identify risk factors. …”
Get full text

Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study—INTERACT MESO by Job P van Kooten, Jacobus W A Burger, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Stijn L W Koolen, Ron H J Mathijssen, Michelle V Dietz, Niels A D Guchelaar

“…The study population consists of adult patients with primary MPM, without extra-abdominal disease, who are not eligible to undergo CRS-HIPEC. According to standard of care work-up for CRS-HIPEC, patients will undergo diagnostic laparoscopy to determine the feasibility of CRS-HIPEC. …”
Get full text

The “real life” efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP by Nicholas J. Campion, Jonas Brugger, Aldine Tu, Victoria Stanek, Faris F. Brkic, Tina J. Bartosik, David T. Liu, Bruna S. Hoehl, Katharina Gangl, Julia Eckl-Dorna, Sven Schneider

“…Methods 97 patients with CRSwNP, who were begun on dupilumab between January 2020 and October 2021, were included. …”
Get full text

Pendidikan Karakter Berbasis Ajaran Agama Islam: Membentuk Generasi Berakhlakul Karimah by Diki Somantri, Husen Arifin

“…The research subjects consisted of teachers and students at SDN Sukarasa who implemented the Islamic Teaching-Based Character Education learning program in Islamic Religion learning as well as the role of the Koranic Teacher. …”
Get full text

Magnetic resonance imaging quantification of left ventricular mechanical dispersion and scar heterogeneity optimize risk stratification after myocardial infarction by Xiaoying Zhao, Li Zhang, Lujing Wang, Wanqiu Zhang, Yujiao Song, Xinxiang Zhao, Yanli Li

“…Methods We enrolled 181 post-MI patients (median age: 55.7 years; 76.8% male) who underwent CMR examinations. LVMD was calculated using the CMR-feature tracking (CMR-FT) technique, defined as the standard deviation (SD) of the time from the R-wave peak to the negative strain peak across 16 myocardial segments. …”
Get full text

Discharge Hemoglobin Association with Long-Term Outcomes of ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention by Ming Gao, Xinying Zhang, Ling Qin, Yang Zheng, Zhiguo Zhang, Qian Tong, Hang Li

“…We analyzed records of 983 STEMI patients who were treated with primary PCI. The primary end point was all-cause mortality at 1 year and 2 years. …”
Get full text

Evaluation of the Level of Salivary sHLA-G in Children Aged 3–5 Years with or without Dental Caries by Mansoureh Bijani, Amrollah Mostafazadeh, Mina Motallebnejad, Ali Bijani, Roghiyeh Pourbagher, Samaneh Gharekhani

“…This analytic cross-sectional study was carried out on 83 healthy children aged 3 to 5 years of both genders, who were divided into three groups based on decayed dental surfaces (ds): group 1, caries-free children (CF, n = 29); group 2, children with 1 ≤ ds ≤ 3, 1 ≤ ds ≤ 4, and 1 ≤ ds ≤ 5 for age 3, 4, and 5 years, respectively (ECC, n = 20); and group 3, children with ds ≥ 4, ds ≥ 5, and ds ≥ 6 for age 3, 4, and 5 years, respectively (S-ECC, n = 34). …”
Get full text

Whole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS) by Yuan Yuan, Daiterigele, Qian Zhang, Chen Du

“…We used the standard long protocol to collect granulosa cells from two groups, who underwent assisted reproduction at the Reproductive Medicine Center of the Affiliated Hospital of Inner Mongolia Medical University, China. …”
Get full text

The Ethical Challenges of Gamification in Iran: Uncovering the Dark Side by Mona Jami Pour, Hamideh Binaei

“…The statistical population of this research consisted of academic experts, specialists, designers, and researchers active in the field of gamification, who were selected and invited to participate using a judgmental sampling method.   …”
Get full text

Knowledge discovery from database: MRI radiomic features to assess recurrence risk in high-grade meningiomas by Chen Chen, Lifang Hao, Bin Bai, Guijun Zhang

“…Model performance was assessed using the C-index. Results WHO grade, age, gender, histogram (Mean, Perc.90%, Perc.99%), Gray-level co-occurrence matrix (S(3, -3)DifVarnc, S(5, 5)Correlat, S(1, 0)SumEntrp, S(2, -2)InvDfMom), Teta1, WavEnLL_s-2 and GrVariance were identified as the significant recurrence factors. …”
Get full text

Risk factors for renal insufficiency and survival implications after radical nephrectomy and thrombectomy in renal cell carcinoma with tumor thrombus: a systematic review by Zhigao Huang, Zhuo Liu, Lin Zhuo, Xin Ma, Zhenbin Jiang, Kewei Chen, Jiyuan Chen, Yuxuan Li, Guoliang Wang, Xiaojun Tian, Hongxian Zhang, Lei Liu, Lulin Ma, Kai Hong, Shudong Zhang

“…Results Overall, a total of 1,668 patients who were diagnosed with RCC and VTT and underwent RN (open/laparoscopic/robotic) with thrombectomy were analyzed. …”
Get full text