Prevalence of Anti-JC Virus (JCV) Antibodies in the Multiple Sclerosis (MS) Population in Cyprus: A Retrospective Study by Sakis Lambrianides, Christiana A. Demetriou, Andis Tillyris, Elena Kkolou, Eftychia Gaglia, Eleni Agkastinioti, Eleni Leonidou, Yiolanda-Panayiota Christou, Savvas S. Papacostas, Kleopas A. Kleopa, Theodoros Kyriakides, Marios Pantzaris

“…We retrospectively collected the demographics of 214 MS patients in Cyprus who were screened for anti-JCV antibodies using the STRATIFY JCV™ assay between September 2011 and June 2018. …”
Get full text

Is it beneficial to use lateral protective crossing K-wires during medial open wedge high tibial osteotomy? A retrospective comparative study by Hossam Fathi Mahmoud, Ahmed Hatem Farhan, Ahmed Mohamed Abdelwahab, Ahmed Mohamed Elshaer, Mahmoud Abdo Mahmoud, Fahmy Samir Fahmy

“…Methods The data of patients fulfilling the inclusion criteria who underwent MOWHTO between May 2021 and August 2022 were retrospectively evaluated. …”
Get full text

Applying a diffusion of innovations framework to characterise diffusion groups and more effectively reach late adopters: a cross-sectional study on COVID-19 vaccinations in Canada... by Tyler Williamson, Jia Hu, Kate Zinszer, Reed Beall, Brian Steele, Ally Memedovich, Aidan Hollis, Taylor Orr, Charleen Salmon

“…Innovators and early adopters were significantly more likely to get vaccinated in settings other than pharmacies or community centres.Conclusion A diffusion group-based analysis brought insight into how vaccination strategies could be tailored to reach each diffusion group sooner, particularly late adopters who encounter more barriers.…”
Get full text

Novel protein-based prognostic signature linked to immunotherapeutic efficiency in ovarian cancer by Shuo-Fu Chen, Liang-Yun Wang, Yi-Sian Lin, Cho-Yi Chen

“…A key obstacle is the lack of reliable biomarkers to identify patients who would benefit significantly from the therapy. …”
Get full text

Acute kidney injury in patients treated with immune checkpoint inhibitors: a single-center retrospective study by Ping Zhou, Bing Liu, Ning Shen, Xiaoting Fan, Shangwei Lu, Zhijuan Kong, Ying Gao, Zhimei Lv, Rong Wang

“…Therefore, we conducted a retrospective study on the incidence, risk factors, clinical features and renal recovery of ICI-AKI in all patients with malignancies treated with ICIs in Shandong Provincial Hospital Affiliated to Shandong First Medical University.Methods In this single-center retrospective cohort study, the data of 904 patients who received immune checkpoint inhibitors (ICIs) treatment were retrospectively analyzed. …”
Get full text

Area under the Curve-Based Dosing of Vancomycin in Critically Ill Patients Using 6-Hour Urine Creatinine Clearance Measurement by Bita Shahrami, Farhad Najmeddin, Saeideh Ghaffari, Atabak Najafi, Mohammad Reza Rouini, Mojtaba Mojtahedzadeh

“…Method. 23 adult critically ill patients with an estimated glomerular filtration rate (eGFR) ≥60 mL/min who received vancomycin infusion were enrolled in this pilot study. …”
Get full text

Vitamin D Supplementation and Hemoglobin Levels in Hypertensive Patients: A Randomized Controlled Trial by Jana B. Ernst, Andreas Tomaschitz, Martin R. Grübler, Martin Gaksch, Katharina Kienreich, Nicolas Verheyen, Winfried März, Stefan Pilz, Armin Zittermann

“…Two hundred patients with 25OHD levels <75 nmol/L who attended the Styrian Vitamin D Hypertension Trial were included, of whom 188 completed the trial. …”
Get full text

‘They went for the test together but came back separately’: a constructivist grounded theory perspective on male engagement in antenatal HIV testing in Bamenda, Cameroon by Lily Haritu Foglabenchi, Nancy Manigha Nyahkeh, Heidi Stöckl, Tanya Marchant

“…Also, couple communication was rare or subtle—mostly initiated by women who suspected spousal infidelity. For some men, HIV testing was a conscious decision to confirm fidelity, for others this was challenged by the fear of sero-discordant results and assumptions that maternal test results were a representation of their sero-status. …”
Get full text

Evaluation of Competency-Based Medical Education (CBME) curriculum implementation for Phase II Medical undergraduates: A qualitative study by KRISHNAMURTHY SOUNDARIYA, ANANDABASKAR NISHANTHI, RAJALAKSHMI MAHENDRAN, MOUROUGUESSINE VIMAL

“…The present study aimed to evaluate the implementation of the CBME curriculum for Phase II medical undergraduates in our institute.Methods: This qualitative study involved faculty members from Pathology, Microbiology, and Pharmacology teaching Phase II medical undergraduates, who participated in three focus groupdiscussions (one per department) to discuss the strategies and challenges in curriculum implementation. …”
Get full text

Effects of Flash Glucose Monitoring on Dietary Variety, Physical Activity, and Self-Care Behaviors in Patients with Diabetes by Satoshi Ida, Ryutaro Kaneko, Kanako Imataka, Kaoru Okubo, Yoshitaka Shirakura, Kentaro Azuma, Ryoko Hujiwara, Hiroka Takahashi, Kazuya Murata

“…This study included outpatients with diabetes using insulin who presented at the Department of Diabetes and Metabolism of the Ise Red Cross Hospital. …”
Get full text

Global analysis of influenza epidemic characteristics in the first two seasons after lifting the nonpharmaceutical interventions for COVID-19 by Xiaowei Chen, Honghong Chen, Fangfang Tao, Yinzi Chen, Ying Zhou, Jian Cheng, Xiling Wang

“…Methods: We analyzed country-specific weekly influenza data (2011-2024) from WHO FluNet and collected COVID-19 NPI timing from official announcements. …”
Get full text

Diagnosis and treatment of thyroblastoma: a case report and review of literature by Xiting Chen, Xiting Chen, Lijuan Xiong, Lijuan Xiong, Hongling Liu, Haoqiang Wang, Donghai Cheng, Wei Wang, Wenyuan He, Bo Xie, Juan Zhou

“…Background and objectiveThe diagnosis of thyroblastoma initially identified as a thyroid malignant teratoma was subsequently classified as a distinct entity by the World Health Organization (WHO) in 2022. This classification was based on the observation that the tumor presents with independent primitive multilineage elements and is frequently associated with DICER1 hotspot mutations.The objective of this study was to explore and investigate the clinicopathologic characteristics, molecular features and treatment strategies of patients with thyroblastoma, followed by a review of the previous relevant literature.MethodsThe clinical manifestations, pathological characteristics, molecular features and treatment strategies of the initial case of thyroblastoma pathologically confirmed in China were analyzed.ResultsThe tumor was revealed to have high invasive potential, rapid disease progression, and primitive multilineage elements of pathology, including immature thyroid epithelium, spindled mesenchymal proliferations, and neuroepithelial blastema. …”
Get full text

Nutritional Status and Educational Performance of School-Aged Children in Lalibela Town Primary Schools, Northern Ethiopia by Muluken Ayalew, Alemayehu Bayray, Abate Bekele, Simegnew Handebo

“…The child anthropometric measures were calculated using AnthroPlus software version 1.0.4 WHO 2007 standards. Bivariable and multivariable ordinal logistic regression were fitted. …”
Get full text

Association between perception of COVID-19 risk, confidence in health services and avoidance of emergency department visits: results from a community-based survey in Portugal by Silvia Lopes, Sónia Dias, Ana Gama, Pedro Laires, Carla Nunes, Patrícia Soares, Ana Rita Pedro, Marta Moniz, Ana Rita Goes

“…Objectives To examine the association between the perception of COVID-19 risk, confidence in health services and avoidance of emergency department (ED) visits in Portugal during the COVID-19 pandemic.Design Community-based, cross-sectional survey.Setting Volunteer sample that completed the online survey between April 2020 and May 2021.Participants 987 participants who perceived needing ED care. Of those, 242 reported avoiding ED visits.Outcome measures Logistic regression models for ED avoidance were conducted to estimate the effect of risk perception and confidence in health services, adjusted for sociodemographics, health status and time.Results The adjusted odds for ED avoidance were higher for participants lacking confidence in health service response to non-COVID-19 conditions (adjusted OR: 6.39; 95% CI 3.19 to 12.82) and COVID-19 (1.81; 1.19 to 2.77) and lower for those perceiving a low risk of being infected at a health provider (0.16; 0.07 to 0.38).Conclusion In our sample, confidence in health services and risk perception of infection at a health provider were associated with the decision to avoid the ED. …”
Get full text

Effect of oxytocin nasal spray pretreatment on postoperative acute stress disorder in patients with accidental traumatic fracture: a single-centre prospective randomised controlled... by Ling Ren, Qingqing Huang, Hengdi Zhang, Jingzheng Zeng, Yi Wen, Haifeng Shu, Gu Gong

“…The trial aims to recruit 328 patients with accidental traumatic fractures who underwent surgical treatment. Participants will be randomly categorised into two groups: a control group (0.9% normal saline nasal spray, 1 mL) and an oxytocin group (oxytocin nasal spray, 1 mL/40 IU) at a ratio of 1:1 using the random number table method. …”
Get full text

Intraoperative Hyperspectral Imaging Predicts Early Allograft Dysfunction and Overall Survival in Liver Transplantation by Andri Lederer, MD, Antonia Alina Geisler, MD, Robert Sucher, MD, Daniel Seehofer, MD, Hans-Michael Hau, MD, Uwe Scheuermann, PD, Sebastian Rademacher, MD

“…We included all patients who underwent orthotopic LT with full-size allografts between 2019 and 2021. …”
Get full text

Hantavirus Cardiopulmonary Syndrome and Diffuse Alveolar Hemorrhage in the Era of COVID-19 by Khizar Hamid, Swaminathan Perinkulam Sathyanarayanan, Touba Naim, Muhammad Hamza, Mirza Omer Mahmood Baig, Emad Abu Sitta

“…We report a patient with a history of alcohol abuse and recent exposure to mice and sick kittens who presented with cough with sputum production, shortness of breath, orthopnea, and new-onset lower extremity edema. …”
Get full text

Surgical Outcomes of Trabeculectomy in Uveitic Glaucoma: A Long-Term, Single-Center, Retrospective Case-Control Study by Rina Kanaya, Riki Kijima, Yasuhiro Shinmei, Akihiro Shinkai, Takeshi Ohguchi, Kenichi Namba, Shinki Chin, Susumu Ishida

“…Age- and sex-matched patients with primary open angle glaucoma (POAG) who underwent MMC-TLE were matched by age and sex and enrolled as controls. …”
Get full text

Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report by Norny Syafinaz Ab Rahman, Nur Alyaa Anisa Mat Harom, Nor Ilyani Mohamed Nazar

“…Case Presentations: This case report presents two cases involving patients with chronic diseases residing in a rural area of Pahang, Malaysia, who participated in pharmacist-led HMR visits. The first case describes a 62-year-old single Malay female with multiple chronic conditions, including Type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, and bronchial asthma, managed with eight prescribed medications. …”
Get full text

Early and midterm efficacy of oxiplex gel on postoperative pain intensity, physical disability, and musculoskeletal power in patients undergoing lumbar discectomy by Alireza Tabibkhooei, Maziar Azar, Mohsen Nabiuni, Javad Jahandideh, Mohsen Benam, Farid Qoorchi Moheb Seraj, Feizollah Ebrahimnia, Ali Moradi

“…Methods A randomized controlled trial was conducted on 56 consecutive patients who were candidates for unilateral lumbar discectomy on one lumbar surface. …”
Get full text