Chemical Composition and Larvicidal Activity of Flower Extracts from Clitoria ternatea against Aedes (Diptera: Culicidae) by Darvin R. Ravindran, Madhuri Bharathithasan, Patmani Ramaiah, Mohd Sukhairi Mat Rasat, Dinesh Rajendran, Shakila Srikumar, Intan H. Ishak, Abd Rahman Said, Rajiv Ravi, Mohamad Faiz Mohd Amin

“…Next, the extracts were evaluated against the early 4th instar larvae of Aedes mosquito vectors following the WHO procedures for larval bioassays. The larvicidal activity of Clitoria ternatea flower extracts evidently affected the early 4th instar larvae of Aedes mosquito vectors. …”
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Development of a Predictive Model of Occult Cancer After a Venous Thromboembolism Event Using Machine Learning: The CLOVER Study by Anabel Franco-Moreno, Elena Madroñal-Cerezo, Cristina Lucía de Ancos-Aracil, Ana Isabel Farfán-Sedano, Nuria Muñoz-Rivas, José Bascuñana Morejón-Girón, José Manuel Ruiz-Giardín, Federico Álvarez-Rodríguez, Jesús Prada-Alonso, Yvonne Gala-García, Miguel Ángel Casado-Suela, Ana Bustamante-Fermosel, Nuria Alfaro-Fernández, Juan Torres-Macho

“…<i>Conclusions</i>: This is the first risk score developed for identifying patients with VTE who are at increased risk of occult cancer using ML tools, obtaining a remarkably high diagnostic accuracy. …”
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Hypophyseal Involvement in Immunoglobulin G4-Related Disease: A Retrospective Study from a Single Tertiary Center by Yang Liu, Linjie Wang, Wen Zhang, Hui Pan, Hongbo Yang, Kan Deng, Lin Lu, Yong Yao, Shi Chen, Xiaofeng Chai, Feng Feng, Hui You, Zimeng Jin, Huijuan Zhu

“…All patients showed a prompt response clinically, but only three patients had normalized serum IgG4 levels. Two patients who took medications for less than six months relapsed. …”
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Atezolizumab, bevacizumab, pemetrexed and platinum for EGFR‐mutant NSCLC patients after EGFR TKI failure: A phase II study with immune cell profile analysis by Shang‐Gin Wu, Chao‐Chi Ho, James Chih‐Hsin Yang, Shu‐Han Yu, Yen‐Feng Lin, Shu‐Chin Lin, Bin‐Chi Liao, Ching‐Yao Yang, Yen‐Ting Lin, Chong‐Jen Yu, Ya‐Ting Chuang, Wei‐Yu Liao, Kah Yi Yap, Weng Si Kou, Jin‐Yuan Shih

“…Furthermore, immune cell profiling may aid in identifying patients who may benefit from this approach. Key points The combination regimen yielded promising efficacy in NSCLC patients after EGFR‐TKI resistance, particularly those with PD‐L1‐positive tumours. …”
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Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease by Harunobu Kawamura, Eiji Sakai, Hiroki Endo, Leo Taniguchi, Yasuo Hata, Akiko Ezuka, Hajime Nagase, Takaomi Kessoku, Eiji Yamada, Hidenori Ohkubo, Takuma Higrashi, Yusuke Sekino, Tomoko Koide, Hiroshi Iida, Takashi Nonaka, Hirokazu Takahashi, Masahiko Inamori, Shin Maeda, Atsushi Nakajima

“…Obscure gastrointestinal bleeding (OGIB) is one of the common complications in patients with chronic kidney disease (CKD), especially those who are on maintenance hemodialysis (HD). However, little is known about the characteristics of the small-bowel lesions in these patients, or of the factors that could predict the presence of such lesions. …”
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Abnormality in optimal forest management by indigenous people in deforestation by A. Mutolib, Y. Yonariza, A. Rahmat

“…Ulayat forest land sales involved government officers, such as high-ranking police officers and army personnel, and entrepreneurs, officials, civil servants, and other parties who supposedly understand forestry law. The study also confirmed that the economic factors driving deforestation are facilitated by the social networks between indigenous people and the people holding power. …”
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A Predictive Model for Super-Response to Cardiac Resynchronization Therapy: The QQ-LAE Score by Xi Liu, Yiran Hu, Wei Hua, Shengwen Yang, Min Gu, Hong-Xia Niu, Li-Gang Ding, Jing Wang, Shu Zhang

“…It is important to identify super-responders who can derive most benefits from cardiac resynchronization therapy (CRT). …”
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Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial by Michael Walsh, Salim Yusuf, Chirag Parikh, Jessica Vincent, P J Devereaux, Francois Lamontagne, Matthew T V Chan, Richard Whitlock, Meaghan Cuerden, Amit X Garg, Andre Lamy, Daniel I Sessler, Kevin Teoh, Ainslie Hildebrand, Yunxia Zuo, Pallav Shah, Seyed Hesameddin Abbasi, Mackenzie Quantz, Jean-Pierre Yared, Nicolas Noiseux, Georgios Tagarakis, Antoine Rochon, Janice Pogue, Abbas Salehiomran

“…The additional kidney data collection first began for patients enrolled after 1 March 2012. In patients who provided consent, the last 6-month kidney outcome data will be collected in 2014. …”
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Dog demography and ecology with reference to rabies in the Amhara region, Ethiopia by Liuel Yizengaw Adnie, Wudu Temesgen Jemberu, Adane Bahiru Woreta, Adugna Berju, Araya Mengistu, Zeleke Tesema Wondie, Wassie Molla, Sefinew Alemu Mekonnen

“…The proportion of households who owned at least one dog was 5.9 %. The average number of dogs per dog-owned household was 1.3. …”
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Temporal trends and differences of SARS-CoV-2-specific antibody responses in symptomatic and asymptomatic subjects: a longitudinal study from Umbria in Italy by Iosief Abraha, Paolo Eusebi, Marta Micheli, Antonella Germani, Erica Pasquarelli, Sofia Pascolini, Rossana Antonietti, Sandro Argenti, Alessandra Fioravanti, Elisa Martini, Luana Aristei, Paola Mancinelli, Maria Letizia Ottaviani, Martina Roselli, Milena Barzacca, Erika Belardinelli

“…We aimed to assess longitudinally the trend of antibody serological titres, their correlation with clinical severity as well as clinical reinfection during a follow-up.Design Longitudinal cohort, 12 months follow-up study.Setting USL Umbria 2.Participants Consecutive subjects aged 15–75 who were discharged with the diagnosis of Sars-Cov-2 from the hospitals of the AUSL Umbria 2, or resulted positive to a PCR test for SARS-CoV-2 infection with or without symptoms were recruited. …”
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Traditional herbal medicine legislative and regulatory framework: a cross-sectional quantitative study and archival review perspectives by Sileshi Dubale, Rashed Edris Usure, Yesuneh Tefera Mekasha, Gemmechu Hasen, Firdos Hafiz, Dereje Kebebe, Sultan Suleman

“…BackgroundThe World Health Organization (WHO) reports that a significant portion of the global population relies on traditional herbal medicine (THM) due to limited access to safe and high-quality modern medical care. …”
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How far back do we need to look to capture diagnoses in electronic health records? A retrospective observational study of hospital electronic health record data by Tom Marshall, Elizabeth Sapey, Miles D Witham, Steve Harris, Rachel Cooper, Chris Plummer, Felicity Evison, James Wason, Heather J Cordell, Suzy Gallier, Fiona E Matthews, Ewan Pearson, Avan A Sayer, Mervyn Singer, Joanne Field, Mohammed Osman, Sian Robinson, Victoria Bartle, Thomas Scharf, Jadene Lewis, Rominique Doal, Peta le Roux, Ray Holding, Paolo Missier

“…This study aimed to ascertain how far back in time electronic hospital records need to be interrogated to capture long-term condition diagnoses.Design Retrospective observational study of routinely collected hospital electronic health record data.Setting Queen Elizabeth Hospital Birmingham (UK)-linked data held by the PIONEER acute care data hub.Participants Patients whose first recorded admission for chronic obstructive pulmonary disease (COPD) exacerbation (n=560) or acute stroke (n=2142) was between January and December 2018 and who had a minimum of 10 years of data prior to the index date.Outcome measures We identified the most common International Classification of Diseases version 10-coded diagnoses received by patients with COPD and acute stroke separately. …”
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Hyperglycemia and Correlated High Levels of Inflammation Have a Positive Relationship with the Severity of Coronavirus Disease 2019 by Wen Zhang, Chuanwei Li, Yu Xu, Binfeng He, Mingdong Hu, Guoqiang Cao, Li Li, Shuang Wu, Xia Wang, Chun Zhang, Jianping Zhao, Jungang Xie, Zihui Xu, Qi Li, Guansong Wang

“…The initial measurement of plasma glucose levels after hospitalization may help identify a subset of patients who are predisposed to a worse clinical course.…”
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Preparation of future teachers for innovative activities in pedagogical and technological educational environment by N. I. Naumkin, N. N. Shekshaeva, V. F. Kupryashkin, E. V. Zabrodina

“…These aspects become especially relevant in relation to the professional training of future technology teachers, who will have to prepare the younger generation for the innovative activity at the initial stage of their training and form a stable opinion among them about the need to acquire knowledge and skills required for innovative activity. …”
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Decrease in platelet count in patients with AKI and its association with major adverse kidney events by Ramón Medina-González, Jose J. Zaragoza, Eduardo M. Hernández-Barajas, Juarez Correa-de Leon, Rolando Claure-Del Granado, Armando Vazquez-Rangel, Liliana M. Pineda-Segura, Martha K. Franco-Garcia, Gael Chávez-Alonso, Juan A. Gómez-Fregoso, Francisco G. Rodríguez-García, Guillermo Navarro-Blackaller, Luz Alcantar-Vallin, Alejandro Martínez Gallardo-González, Gabriela J. Abundis-Mora, Guillermo García-García, Jonathan S. Chávez-Iñiguez

“…The mean baseline platelet count was 194 x 103 cells/µL, and 65% of the KDIGO3 patients met these criteria. Those who underwent hemodialysis (HD) had lower platelet counts. …”
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Risk factors associated with mortality and pathogen characteristics of bloodstream infection-induced severe sepsis in the pediatric intensive care unit: a retrospective cohort stud... by Jian Chen, Jian Chen, Haixin Huang, Ruichen Zhang, Yueqiang Fu, Chunmei Jing

“…The detection rates of extended-spectrum cephalosporin resistance (ECR) and fluoroquinolone resistance (FQR) in Escherichia coli (E. coli) were higher than those in Klebsiella pneumoniae.ConclusionIn the PICU, higher mortality was observed in children with BSI-induced severe sepsis who presented with elevated pSOFA scores and low P/F values. …”
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Study of the relationships of polymorphisms of the folate cycle genes with the levels of homocysteine and folic acid as risk factors of cardiovascular disorders in the post-covid p... by A.A. Shuprovych, O.V. Zinych, N.M. Kushnareva, K.P. Komisarenko

“…The aim of the work was to identify the interrelationships of gene polymorphisms of associations between folate cycle enzyme gene polymorphisms and cardiometabolic risk factors such as increased serum homocysteine levels and folic acid deficiency in patients in the post-covid period. In 51 patients who suffered from COVID-19, a general clinical and laboratory examination, and assessment of serum homocysteine and folic acid concentrations by immunoenzymatic method was carried out. …”
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Liraglutide Decreases Liver Fat Content and Serum Fibroblast Growth Factor 21 Levels in Newly Diagnosed Overweight Patients with Type 2 Diabetes and Nonalcoholic Fatty Liver Diseas... by Xinyue Li, Xiaojuan Wu, Yumei Jia, Jing Fu, Lin Zhang, Tao Jiang, Jia Liu, Guang Wang

“…FGF21 levels significantly decreased in patients who had a significant decrease in liver fat content (≥29%) (95% CI: -262.8, -55.1, P=0.006); however, there was no significant change in the patients without a significant decrease in liver fat content (<29%) (95% CI: -60.0, 54.1, P=0.899). …”
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A retrospective study of pembrolizumab combined with XELOX regimen in the treatment of advanced gastric cancer by FENG Huizhi, LIU Jingmei, BU Xiaoqian

“…Methods: Clinical data of patients with advanced gastric cancer who were admitted to Shanxi Province Cancer Hospital from March 2020 to August 2022 were retrospectively collected. …”
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Th1/Th2 Cells and Associated Cytokines in Acute Hepatitis E and Related Acute Liver Failure by Jian Wu, Yurong Guo, Xuan Lu, Fen Huang, Feifei Lv, Daqiao Wei, Anquan Shang, Jinfeng Yang, Qiaoling Pan, Bin Jiang, Jiong Yu, Hongcui Cao, Lanjuan Li

“…Seventeen healthy controls (HCs) were also included who were negative for anti-HEV IgM and IgG. Results. …”
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