Effects of systemic glucocorticosteroids on peripheral neutrophil functions in asthmatic subjects: an ex vivo study by P. L. Paggiaro, L. Bancalari, D. Giannessi, W. Bernini, G. Lazzerini, R. Sicari, E. Bacci, F. L. Dente, B. Vagaggini, R. De Caterina

“…After treatment, there was no significant change in all neutrophil functions, except for a decrease in neutrophil chemotaxis in subjects who showed an FEV1 increase > 20% after GCS treatment (from 131 ± 18 to 117 ± 21 μm, p = 0.005). …”
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Sofosbuvir Based Regimens in the Treatment of Chronic Hepatitis C with Compensated Liver Cirrhosis in Community Care Setting by Vijay Gayam, Amrendra Kumar Mandal, Mazin Khalid, Osama Mukhtar, Arshpal Gill, Pavani Garlapati, Mowyad Khalid, Mohammed Mansour

“…Overall, SVR 12 after treatment was achieved in 90% in patients who received one of the two DAA regimens (89.7% in LDV/SOF group and 92% in SOF/VEL group). …”
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Disease burden of influenza in Spain: A five-season study (2015–2020) by Iván Sanz-Muñoz, Irene Arroyo-Hernantes, Alejandro Martín-Toribio, Marina Toquero-Asensio, Javier Sánchez-Martínez, Carla Rodríguez-Crespo, Silvia Rojo-Rello, Marta Domínguez-Gil, Marta Hernández-Pérez, Eduardo Tamayo, Ruth Gil-Prieto, Ángel Gil-de-Miguel, José M Eiros

“…More than 60% of those hospitalized were over 65 years of age, and approximately 82% of those who died were elderly, demonstrating that the greatest burden of hospitalization and mortality is centered on this age group. …”
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Support for, and perceived effectiveness of, the UK soft drinks industry levy among UK adults: cross-sectional analysis of the International Food Policy Study by David Hammond, Jean Adams, Martin White, David Pell, Tarra Penney, Lana Vanderlee

“…Design Cross-sectional online survey.Setting UK.Participants UK respondents to the 2017 International Food Policy Study aged 18–64 years who provided information on all variables of interest (n=3104).Outcome measures Self-reported perceived effectiveness of, and support for, the SDIL.Results Most participants supported the SDIL (70%), believed it would be effective (71%), had a positive attitude to SSBs (62%), had knowledge of the link between SSBs and obesity (90%), and trusted messages from health experts (61%), but not those from the food and beverage industry (73%). …”
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Cholesterol, triglycerides, HDL, and nitric oxide as determinants of resting heart rate variability in non-hospitalized mild post-COVID individuals: a cross-sectional study by Lucivalda Viegas de Almeida, Aldair Darlan Santos-de-Araújo, Luís Cláudio Nascimento da Silva, Patricia Martins Santos, Mariana Campos Maia, Victória Pereira Frutuoso, Daniel Santos Rocha, Adriana Sousa Rêgo, Daniela Bassi-Dibai

“…Individuals of both sexes, aged ≥ 18 years, who tested positive for SARS-CoV-2 according to the RT-PCR test, without the need for hospitalization, were included. …”
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Severe reversible cardiomyopathy associated with adrenal crisis caused by isolated adrenocorticotropin deficiency: a case report by Li Wang, Fangfang Bu, Lanjie He, Guihua Yao, Guihua Yao

“…In this case report, we describe a 74-year-old male patient who was in good physical health and was admitted to our hospital with a sudden onset of fever and confusion that was complicated by hyponatremia and hypotension. …”
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Treatment of a femoral neck fracture in a patient with dwarfism: a case report by Junyan Zhao, Liuliu Chen, Kun He, Muyao Li, Zhenwen Li, Hui Lin, Songjun Li

“…Case presentation This report presents the case of a 30-year-old female with congenital pituitary dwarfism who sustained a subcapital femoral neck fracture following trauma. …”
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Mediation of the effect of prenatal maternal smoking on time to natural menopause in daughters by birthweight-for-gestational-age z-score and breastfeeding duration: analysis of tw... by Darina Peycheva, Leah Li, Mary Fewtrell, Richard Silverwood, Rebecca Hardy

“…Results Prenatal maternal smoking was associated with lower birthweight z-scores [β: -0.29; 95% CI -0.34, -0.24] and reduced breastfeeding duration [RRR< 1month: 0.90; 95% CI 0.79, 1.02; RRR≥ 1 month: 0.66; 95% CI 0.59, 0.73 relative to women who were never breastfed]. Greater z-score for birthweight [HR: 0.96; 95% CI 0.91, 1.01] and longer breastfeeding duration [HR≥ 1 month: 0.84; 95% CI 0.74, 0.96] were associated with lower hazards for earlier age at natural menopause. …”
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The use of methylene blue in adult patients with septic shock: a systematic review and meta-analysis by Ka Ting Ng, Pei En Kwok, Wei En Lim, Wan Yi Teoh, Mohd Shahnaz Hasan, Mohd Fitry Zainal Abidin

“…As compared to the placebo, our pooled analysis showed that methylene blue significantly increased mean arterial pressure (MD: 1.34 mmHg, 95% CI 0.15 to 2.53, p = 0.03, level of evidence: very low). Patients who were given methylene blue were associated with statistically lower mortality rate (OR = 0.49, 95% CI 0.27 to 0.88, p = 0.02, level of evidence: low), reduced serum lactate levels (MD: -0.76 mmoL.L-1, 95% CI -1.22 to -0.31, p = 0.0009, level of evidence: low), reduced length of hospital stay (MD: -1.94 days, 95% CI -3.79 to -0.08, p = 0.04, level of evidence: low), and increased PaO2/FiO2 (MD: 34.78, 95% CI 8.94 to 60.61, p = 0.008, level of evidence: low). …”
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Risk Factors for Microvascular Complications of Diabetes in a High-Risk Middle East Population by Sohaila Cheema, Patrick Maisonneuve, Mahmoud Zirie, Amin Jayyousi, Hekmat Alrouh, Amit Abraham, Sura Al-Samraye, Ziyad Mahfoud, Ibrahim Mohammed Al-Janahi, Buthaina Ibrahim, Albert B. Lowenfels, Ravinder Mamtani

“…We collected information via a structured questionnaire and directly from the patient’s record on 1034 adult type 2 diabetic patients who were attending outpatient clinics in Qatar. …”
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Charlson syndrome index predicted survival in pancreatic cancer patients received immunotherapy by Nan Zhang, Nan Zhang, Shiyun Chen, Yue Shi, Zhikuan Wang, Ru Jia, Guanghai Dai, Guanghai Dai

“…Therefore, this study aims to elucidate the association between CCI and survival rates in real-world settings for pancreatic cancer patients received immunotherapy.MethodsA total of 104 patients with advanced pancreatic cancer who received immunotherapy at the General Hospital of the People’s Liberation Army between September 2015 and September 2020 were included in this study. …”
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High rate of false positive malaria rapid diagnostic tests in a district hospital in Uganda by Susanne E. Mortazavi, Susanne E. Mortazavi, Allan Lugaajju, Anna-Clara Ivarsson, Sara Karlsson Söbirk, Sara Karlsson Söbirk, Hans Norrgren, Hans Norrgren, Kristina E. M. Persson, Kristina E. M. Persson

“…It is essential that healthcare facilities use RDTs validated and recommended by the World Health Organization (WHO) to ensure high specificity and accuracy, particularly in resource-limited settings where alternative diagnostic methods may not be available.…”
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Machine learning assisted radiomics in predicting postoperative occurrence of deep venous thrombosis in patients with gastric cancer by Yuan Zeng, Yuhao Chen, Dandan Zhu, Jun Xu, Xiangting Zhang, Huiya Ying, Xian Song, Ruoru Zhou, Yixiao Wang, Fujun Yu

“…Methods Included in this retrospective study were eligible patients who underwent surgery for GC. CT imaging data from these patients were collected and divided into a training set and a validation set. …”
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Silent struggles: a qualitative study exploring mental health challenges of undergraduate healthcare students by Shahd Al-Najdi, Abdulla Mansoor, Ola Al Hayk, Najah Al-Hashimi, Kamran Ali, Alaa Daud

“…A purposive sampling method was used to recruit students from five healthcare disciplines- Medicine, Dentistry, Pharmacy, Health Sciences and Nursing- who had self-reported mild to moderate depressive symptoms based on the Patient Health Questionnaire (PHQ-9) and Depression Anxiety and Stress Scale (DASS21). …”
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Challenges of healthcare financing in the world’s largest refugee camp: a mixed-method study among healthcare stakeholders for Rohingya refugees in Bangladesh by Isabel Smith, Imdadul Haque Talukdar, Sayeeda Tarannum, M A Rifat, Priyanka Boga, Jubayer Mumin, Pablo André Veronés, Ziba Mahdi, Syeda Saima Alam, Arif Faysal Khan

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Epidemiology of Yellow Fever in Nigeria: Analysis of Climatic, Ecological, Socio-Demographic, and Clinical Factors Associated with Viral Positivity Among Suspected Cases Using Nati... by Stephen Eghelakpo Akar, William Nwachukwu, Oludare Sunbo Adewuyi, Anthony Agbakizua Ahumibe, Iniobong Akanimo, Oyeladun Okunromade, Olajumoke Babatunde, Chikwe Ihekweazu, Mami Hitachi, Kentaro Kato, Yuki Takamatsu, Kenji Hirayama, Satoshi Kaneko

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Thickness of Subcutaneous Fat Is a Predictive Factor of Incisional Surgical Site Infection in Crohn’s Disease Surgery: A Retrospective Study by Xingchen Cai, Weisong Shen, Zhen Guo, Yi Li, Lei Cao, Jianfeng Gong, Weiming Zhu

“…Patients and Methods. Patients with CD who had undergone abdominal surgery from January 2014 to January 2017 were included in this retrospective study. …”
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Advances in the pilot point inverse method: Où En Sommes-Nous maintenant? by White, Jeremy, Lavenue, Marsh

“…At a conference some years ago, one of the attendees came up to Ghislain de Marsily and asked, “Excuse me, but aren’t you the de Marsily who developed the Pilot Point Method? It is an honor to meet you.” …”
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Racial diversity amongst Otolaryngology-Head and Neck Surgery programs in Canada by Garret Horton, Elysia Grose, Tanya Chen, Oluwaseun Daniel Davies, Dongho Shin, Ian Witterick, Paolo Campisi, Yvonne Chan

“…However, women continue to be under-represented in more senior positions, especially women who are visible minorities. Further investigation into the systemic factors that may contribute to this disparity is needed as well as effective ways to promote diversity amongst academic OHNS departments at all levels of academic seniority. …”
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Supervision, performance assessment, and recognition strategy (SPARS) – a multipronged strategy to strengthen medicines management in Nepal: pilot study methods and baseline result... by Nirajan Bhusal, Anup Bastola, Reekesh Shrestha, Narendra Kumar Khanal, Birna Trap

“…From the middle of 2022, we trained 60 MM supervisors who began conducting supervisory visits at 284 health facilities in 12 randomly selected pilot districts located in three provinces. …”
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