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Women's perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey
Published 2015-06-01“…The study revealed that few women knew of thalidomide, suggesting that the general awareness among women of the teratogenic effects of thalidomide is declining, but it has left a general scepticism about safety of medication in pregnancy. …”
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22
Post-Autologous (ASCT) Stem Cell Transplant Therapy in Multiple Myeloma
Published 2014-01-01“…Thalidomide use has been associated with a meaningful improvement in PFS and EFS, however, with substantial side effects. …”
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23
IgD Multiple Myeloma Paraproteinemia as a Cause of Myositis
Published 2010-01-01“…Few months after polymyositis remission, myeloma relapsed and the patient was treated with thalidomide for six years with good remission. Soon after thalidomide suspension, MM relapsed again and the patient came to our observation for a new onset of neuromuscular symptoms. …”
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24
Think Stop before Going 'Off-Label'
Published 2004-01-01“…Only after careful and extensive review of all available safety and efficacy data derived from preclinical and clinical trials will a regulatory body approve the licensing of a drug for a specific medical condition ('indication'). Experience with thalidomide, fialuridine and troglitazone, to name a few, reveal that despite these efforts, the process is not infallible. …”
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25
Management of Fistulas in Patients with Crohn'S Disease: Antibiotic to Antibody
Published 2001-01-01“…Antibiotics, cyclosporine, methotrexate and thalidomide have been used in uncontrolled trials; only azathioprine, 6-mercaptopurine and infliximab have been assessed in double-blind, placebo controlled studies. …”
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26
Case of Stroke from Cerebral Vasculitis following Carfilzomib, Lenalidomide, and Dexamethasone Therapy in a Patient with Relapsing Multiple Myeloma
Published 2019-01-01“…Lenalidomide, a synthetic derivation of thalidomide, in recent years, has been the backbone of multiple myeloma treatment leading to improved survival. …”
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27
Isolated Langerhans Cell Histiocytosis of the Vulva in a 28-Year-Old Lady: A Report of a Case and Brief Review of the Literature
Published 2022-01-01“…Herein, we report the case of a 28-year-old woman with isolated vulvar LCH, misdiagnosed with herpes simplex infection, successfully treated with thalidomide.…”
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28
Medical Therapy of Steroid-Resistant Crohn's Disease
Published 2000-01-01“…Limited data are available on the use of tacrolimus, mycophenolate mofetil and thalidomide. Steroid-resistant Crohn’s disease, while involving a small minority of patients, continues to present a difficult therapeutic challenge.…”
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29
Microbiological Isolation of Sporothrix Schenckii in an Immunocompromised Patient. A Case Report
Published 2014-08-01“…We present the case of 67-year-old white patient of rural origin with a history of myelofibrosis that had evolved for ten years and was treated with thalidomide and prednisone. He was admitted to the University General Hospital of Cienfuegos in August 2013 because of skin lesions on the left cheek, chest and forearms. …”
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30
Recurrent Obscure Gastrointestinal Bleeding: Dilemmas and Success with Pharmacological Therapies. Case Series and Review
Published 2009-01-01“…In the third case, however, the addition of low-dose thalidomide stopped bleeding for a period of at least 23 months.…”
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31
Successful Use of Cyclophosphamide as an Add-On Therapy for Multiple Myeloma Patients with Acquired Resistance to Bortezomib or Lenalidomide
Published 2013-01-01“…Novel agents such as thalidomide, lenalidomide, and bortezomib have been shown to possess potent activity against multiple myeloma. …”
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32
Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions
Published 2015-01-01“…Recently, a few studies have reported the potential value of the proteasome inhibitor bortezomib and thalidomide in PBL patients. The introduction of genes encoding artificial receptors called chimeric antigen receptors (CARs) and CAR-modified T cells targeted to the B cell-specific CD19 antigen have demonstrated promising results in multiple early clinical trials. …”
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33
Acute Lymphoblastic Leukemia following Lenalidomide Maintenance for Multiple Myeloma: Two Cases with Unexpected Presentation and Good Prognostic Features
Published 2018-01-01“…Patients develop sALL after median of 32.5 months (range, 20–84) from being on lenalidomide or thalidomide maintenance, often presenting with cytopenias, display low tolerance to chemotherapy, but remission can often be achieved.…”
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34
Two Rare Complications in One Patient: Acquired von Willebrand Syndrome Associated with Intracranial Plasmacytoma
Published 2019-01-01“…The patient received induction therapy with bortezomib, thalidomide, and dexamethasone (VTD), followed by high-dose melphalan chemotherapy and autologous stem cell transplantation, and then VTD consolidation, and finally maintenance with lenalidomide. …”
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35
Synthesis, Characterization, and Biological Evaluation of Gabapentinoid Hybrids with Isoindole-1,3(2H)-Dione Moiety as Potential Antioxidant, Antimicrobial, and Anticancer Agents
Published 2023-01-01“…Compound 2 is highly effective against Caco-2 cells and more effective than thalidomide, with IC50 value less than 1 μmol/L. Conclusion. …”
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36
Use of Minimal Residual Disease Status to Reduce Uncertainty in Estimating Long-term Survival Outcomes for Newly Diagnosed Multiple Myeloma Patients
Published 2023-01-01“…**Methods:** Standard and response-based PSMs, estimating patient life-years (LYs) over a lifetime horizon, were developed for NDMM patients treated with bortezomib, thalidomide, and dexamethasone (BTd) with or without daratumumab as induction and consolidation therapy. …”
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37
Fetal Tetra-Amelia Birth: A Case Report
Published 2024-01-01“…Maternal diabetes, amniotic band syndrome, TORCH (toxoplasmosis, rubella cytomegalovirus, herpes simplex, and HIV) infection, alcohol consumption, and intrauterine exposure to some drugs like thalidomide, glucocorticoids, and sedatives are risk factors for limb malformation. …”
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Case report: Successful therapy with recombinant human vascular endostatin in an elderly man with colon telangiectasia and idiopathic thrombocytopenic purpura
Published 2025-01-01“…Additionally, conventional therapies such as estrogen and thalidomide were contraindicated due to the comorbidity of ITP. …”
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Characteristics and outcomes of secondary acute lymphoblastic leukemia (sALL) after multiple myeloma (MM): SEER data analysis in a single-center institution
Published 2025-01-01“…Conclusions: Patients with sALL combined with an antecedent MM, especially those with long-term exposure to immunomodulatory agents such as thalidomide or lenalidomide, should be cautiously evaluated and managed with a comprehensive approach.…”
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40
Histologic and Endoscopic Similarity between Nodular Gastric Antral Vascular Ectasia and Gastric Hyperplastic Polyps Potentially Causing Treatment Delays
Published 2019-01-01“…There is not a lot of evidence supportive of pharmacological treatment of GAVE with estrogen-progesterone, tranexamic acid, and thalidomide. Serial endoscopic band ligation as well as detachable snares in the management of nodular GAVE refractory to argon plasma coagulation has also been tried. …”
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