Study of the Prevalence of Cytomegalovirus in Children with Malignancy in Southwestern Iran from 2016-2023 by Arash Alghasi, Saeed Bitraf, Roya Salehi Kahyesh, Yasin Alidadi, Homayoun Yousefi, Manouchehr Makvandi

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Hemophilia A Haplotypes in Southwestern Iran by Bizhen Keikhaei Dehdezi, Ali Khodadadi, Arta Farhadi Kia, Faezeh Abbasi, Saeed Bitraf, Roya Salehi Kahyesh

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A novel compound heterozygous mutation in the DYNC2H1 gene in a Chinese family with Jeune syndrome by Sujie Xiong, Guangyao Hu, Yao Zhou, Fei Sun, Yanlin Ma

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Study of Frequency and Characteristics of Red Blood Cell Alloimmunization in Thalassemic Patients: Multicenter Study from Palestine by Adham Abu Taha, Ahmad Yaseen, Sa’d Suleiman, Omar Abu Zenah, Hammam Ali, Rania Abu Seir, Khaled Younis

“…Background. β-Thalassemia is a common inherited hemolytic disorder in Palestine. …”
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Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice by Parinda Jamrus, Nuttanan Pholngam, Benjaporn Kiatpakdee, Kittikun Viwatpinyo, Jim Vadolas, Sukonthar Ngampramuan, Saovaros Svasti, Pornthip Chaichompoo

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Alpha-Hemoglobin-Stabilizing Protein: An Erythroid Molecular Chaperone by Maria Emília Favero, Fernando Ferreira Costa

“…Reduced AHSP mRNA expression has been associated with clinical variability in some cases of β-thalassemia. It has been shown that αHb variants may also impair AHSP-αHb interactions, leading to pathological conditions that resemble α-thalassemia syndromes. …”
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Prevalence and mortality trends of hemoglobinopathies in Italy: a nationwide study by Barbara Gianesin, Frédéric B. Piel, Khaled M. Musallam, Susanna Barella, Maddalena Casale, Elena Cassinerio, Rosario Di Maggio, Antonia Gigante, Maria Rita Gamberini, Giovanna Graziadei, Roberto Lisi, Filomena Longo, Aurelio Maggio, Raffaella Origa, Annamaria Pasanisi, Silverio Perrotta, Antonio Giulio Piga, Valeria Maria Pinto, Rosamaria Rosso, Giacomo Robello, Giovanna Russo, Marco Zecca, Lucia De Franceschi, Gian Luca Forni, Italian Hemoglobinopathies National Survey Group

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Seroprevalence of Hepatitis C, Hepatitis B, Cytomegalovirus, and Human Immunodeficiency Viruses in Multitransfused Thalassemic Children in Upper Egypt by Ramadan A. Mahmoud, Abdel-Azeem M. El-Mazary, Ashraf Khodeary

“…Frequent blood transfusions in thalassemia major children expose them to the risk of transfusion-transmitted infections (TTIs). …”
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Intestinal Parasites Infection in Children with Cancer in Ahvaz, Southwest Iran by Roya Salehi Kahyesh, Arash Alghasi, Shekoufe Haddadi, Asaad Sharhani

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Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies by Prathibha Babu Chandraprabha, Manoj Kumar K. Azhagiri, Vigneshwaran Venkatesan, Wendy Magis, Kirti Prasad, Sevanthy Suresh, Aswin Anand Pai, Srujan Marepally, Alok Srivastava, Kumarasamypet Murugesan Mohankumar, David I. K. Martin, Saravanabhavan Thangavel

“…Abstract Background Sickle cell disease (SCD) and β-thalassemia patients with elevated gamma globin (HBG1/G2) levels exhibit mild or no symptoms. …”
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Generation of a USP9Y knockout human embryonic stem cell line with CRISPR-Cas9 technology by Sai Wei, Yuting Zhen, Chao Sun, Yanlin Ma, Qi Li, Luan Wen

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Surgical, non-traumatic splenopathies by Ivonne López Masó, Rafael Trinchet Soler, Manuel García Artiles, Ada Arlenis Pérez Mayo

“…Illnesses like idiopatic thrombocytopenic purple, hereditary spherocytosis, sickle cell anemia, beta thalassemia, portal hypertension and other non-traumatic disseases that carry out with congestive splenomegaly and hypersplenism, find an effective alternative with the total or partially splenectomy. …”
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The endocannabinoid system’s genetic polymorphisms in sickle cell anemia patients by Amanda Cristina Meneguetti Berti, Vanessa da Silveira Ramos de Castro, Gabriela Silva Arcanjo, Aderson da Silva Araujo, Antonio Roberto Lucena-Araujo, Marcos André Cavalcanti Bezerra, Lucas Gazarini, Danilo Grünig Humberto da Silva, Edis Belini-Júnior

“…SCA was detected with HPLC, and the Hb SS genotype was confirmed with PCR-RE. Alpha thalassemia mutations were detected with Multiplex-PCR, and SNP genotyping was performed using TaqMan genotyping assays. …”
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Smart approaches for encouraging the blood donation by Rakesh Sharma, Debadri Banerjee, Anupama Singh, Vikas Anand Saharan

“…Blood is a life saver in many emergencies like accidents or for the patients suffering from deadly diseases such as cancer and thalassemia. Conventionally, blood collection is done in five steps, i.e., recruitment, screening, physical examination, collection, and postdonation care. …”
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Targeting the Hepcidin-Ferroportin Axis in the Diagnosis and Treatment of Anemias by Elizabeta Nemeth

“…Deficient production of hepcidin causes systemic iron overload in iron-loading anemias such as beta-thalassemia; whereas hepcidin excess contributes to the development of anemia in inflammatory disorders and chronic kidney disease, and may cause erythropoietin resistance. …”
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Effect of L-carnitine on lipid biomarkers of oxidative stress in chronic hemodialysis patients: a randomized controlled trial by Shokoh Shayanpour, Seyyed Seyfollah Beladi Mousavi, Hossain Karimpourian, Khojasteh Hoseinynejad, Kambiz Ahmadi Angali

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The Antioxidant Effect of Erythropoietin on Thalassemic Blood Cells by Johnny Amer, Mutaz Dana, Eitan Fibach

“…Because of its stimulating effect on RBC production, erythropoietin (Epo) is used to treat anemia, for example, in patients on dialysis or on chemotherapy. In β-thalassemia, where Epo levels are low relative to the degree of anemia, Epo treatment improves the anemia state. …”
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Sprengel's Deformity Associated with Musculoskeletal Dysfunctions and Renal Anomalies: A Case Report by Mohammad Hossein Kariminasab, Masoud Shayeste-Azar, Majid Sajjadi Saravi, Mehrdad Taghipour Gorgikolai

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Thalassemic DNA-Containing Red Blood Cells Are under Oxidative Stress by Mutaz Dana, Eugenia Prus, Eitan Fibach

“…Using flow cytometry methodology, we measured oxidative status parameters of these cells in patients with β-thalassemia. In each patient studied, these cells had higher content of reactive oxygen species and exposed phosphatidylserine compared with their DNA-free counterparts. …”
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Two Novel Variants in the ATRX Gene Associated with Variable Phenotypes by D. Hettiarachchi, B. A. P. S. Pathirana, P. J. Kumarasiri, V. H. W. Dissanayake

“…The X-linked alpha-thalassemia mental retardation (ATR-X) syndrome is a rare genetic condition caused by mutations in the X‐encoded gene ATRX. …”
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