Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions by Marina G. Gobbo, Nishtman Dizeyi, Per-Anders Abrahamsson, Per-Anders Bertilsson, Viviane Sanches Masitéli, Eloisa Zanin Pytlowanciv, Sebastião R. Taboga, Rejane M. Góes

“…MLT treatment impeded apoptosis p=0.02 and augmented proliferation p=0.0008 and PCNA content in prostate following long-term diabetes due to restoration of testosterone levels and expression of melatonin receptor type 1B. …”
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Hyperandrogenism, Elevated 17-Hydroxyprogesterone and Its Urinary Metabolites in a Young Woman with Ovarian Steroid Cell Tumor, Not Otherwise Specified: Case Report and Review of t... by Felix C. K. Wong, Angela Z. Chan, W. S. Wong, Angel H. W. Kwan, Tracy S. M. Law, Jacqueline P. W. Chung, Jeffrey S. S. Kwok, Angel O. K. Chan

“…While a diagnosis of polycystic ovary syndrome (PCOS) with its associated metabolic disturbances was initially considered, serum total testosterone, androstenedione, and 17-hydroxyprogesterone (17-OHP) measured by liquid chromatography tandem mass spectrometry (LC-MS/MS) were significantly increased. …”
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Associations between subjective and objective measures of stress and load: an insight from 45-week prospective study in 189 elite athletes by Kristina Drole, Mojca Doupona, Kathrin Steffen, Kathrin Steffen, Aleš Jerin, Aleš Jerin, Armin Paravlic, Armin Paravlic

“…Blood samples were collected five times during the 2022/23 season to measure cortisol and the free testosterone to cortisol ratio (FTCR). We derived a “load” variable as the sum of training, competition, academic and work hours and calculated acute, chronic, and acute-to-chronic ratio variables for both load and stress. …”
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Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries by Yi-Ping Zhong, Ying Ying, Hai-Tao Wu, Can-Quan Zhou, Yan-Wen Xu, Qiong Wang, Jie Li, Xiao-Ting Shen, Jin Li

“…The body mass index, basal luteinizing hormone, and testosterone levels were significantly lower in patients with ovulatory PCO compared to those in patients with PCOS. …”
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Association between sleep deprivation and fertility - a literature review by Adriana Dukacz, Anna Konarska, Anna Machowiak, Barbara Ufnalska, Justyna Lisiecka, Mateusz Janik, Michał Nowak, Joanna Rychlewska-Duda, Wojciech Firlej, Artur Fabijański

“…There is a probability that Leydig cells function and count, cortisol secretion and testosterone levels can be affected but for now we have to conduct more research to rule it out or confirm. …”
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Plasma miRNAs in polycystic ovary syndrome drive endometrial cancer progression: insights into molecular pathways and therapeutic targets by Xuedan Lai, Ling Wu, Peihong Lin, Lijiao You, Jianwen Ye

“…Two-sample Mendelian randomization analysis identified potential causal relationships between AURKA gene expression and PCOS or UCEC. Testosterone and estradiol might have adverse roles in UCEC, while drugs like troglitazone, valproic acid, retinoic acid, and progesterone demonstrated various effects on gene expression and cellular processes. …”
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The dual impact: physiological and psychological effects of rapid weight loss in wrestling by Barış Sarıakçalı, Fatma Neşe Şahin, Burhan Başoğlu, Levent Ceylan, Özkan Güler, Bade Yamak, Gökhan Arıkan, Gizem Ceylan Acar, Gülşah Sekban, Mehmet Vakıf Durmuşoğlu, Sezen Çimen Polat, Hamza Küçük

“…Levels of creatine, BUN, sodium, hematocrit, hemoglobin, LDH, and cortisol increased, while albumin, testosterone, and FSH levels decreased. There were no significant differences in potassium, ALT, AST, TSH levels. …”
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Characterisation of Chemical Constitutes and Spermatogenic Activity of Ushir (Vetiveria Zizanioides Linn) versus Ikshu (Saccharum Officinarum Linn) in Male Wistar Rats: A Research... by Akshay Sudhir Pargaonkar, Jaymala Jadhav, Bhagyashree Ratan Jibkate, Minakshi Urkude

“…Parameters that will be assessed include sperm morphology, sperm motility, pH, agglutination, sperm count, serum testosterone levels and histopathology. The experimental study will be conducted as per Organisation for Economic Cooperation and Development (OECD) guidelines. …”
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Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models by Anna MP. Stanger, Marlon Arnone, Pauline Hanns, Lucca M. Kimmich, Jessica Kübler, Sarah Gekeler, Elsa S. Görsch, Lea Kramer, Marcelle Baer, Jan C. Schroeder, Taylor S. Mills, Martina Konantz, Saskia S. Rudat, Claudia Lengerke

“…Here we report that, next to leukemic cell characteristics, recipient sex highly influences the outgrowth of AML cells in PDX models, with females being much better repopulated than males in primary as well as secondary transplantation assays. Testosterone may be the more important player since, strikingly, better engraftment was seen in castrated versus control male recipients, while ovariectomy did not significantly impair engraftment in females. …”
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Microplastics: A threat to Fetoplacental unit and Reproductive systems by Abass Toba Anifowoshe, Md Noor Akhtar, Abisola Majeed, Asem Sanjit Singh, Toyyibah Funmilayo Ismail, Upendra Nongthomba

“…They also bioaccumulate in testes, altering spermatogenesis, spermatozoa morphology, testosterone production, body weights, and inflammation as reported in mice. …”
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Male Central Precocious Puberty: Serum Profile of Anti-Müllerian Hormone and Inhibin B before, during, and after Treatment with GnRH Analogue by Romina P. Grinspon, Luz Andreone, Patricia Bedecarrás, María Gabriela Ropelato, Rodolfo A. Rey, Stella M. Campo, Ignacio Bergadá

“…After GnRHa withdrawal, AMH declined concomitantly with the rise in serum testosterone. At diagnosis, inhibin B was elevated and decreased throughout therapy, remaining in the upper normal prepubertal range. …”
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The Effect of Low Carbohydrate Diet on Polycystic Ovary Syndrome: A Meta-Analysis of Randomized Controlled Trials by Xiaoshuai Zhang, Yang Zheng, Yanan Guo, Zhiwen Lai

“…The primary outcomes included the changes in BMI, homeostatic model assessment for insulin resistance (HOMA-IR), and blood lipids, including total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), follicle-stimulating hormone (FSH), luteotropic hormone (LH), total testosterone (T), and sex hormone-binding globulin (SHBG). …”
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Role of p57KIP2 in Stem and Progenitor Leydig Cells of Mouse Testes by Seung Hyun Park, Kyung Noh Yoon, Yang Xu, Myung Chan Gye

“…Steroidogenic differentiation of PLCs was examined by progesterone and testosterone production in cell culture. Results: From postnatal day (PND) 1 to 14, p57KIP2(+) spindle-shaped cells in the testis interstitium were α-smooth muscle actin (αSMA)(-), a peritubular myoid cells marker, suggesting that they are SLCs and PLCs. …”

Woxuanzhongzhou formula improves DHEAS and high-fat diet-induced IR and anovulatory mice via AMPK/PGC1- α/Irisin pathway by Haijuan Liu, Guohua Wang, Conglu Sui, Yanan Guo, Xiangyu He

“…Significant reductions were observed in body weight, serum testosterone, luteinizing hormone, luteinizing hormone/ follicle-stimulating hormone ratio, FINS, and HOMA-IR. …”
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Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages by Hiroki Yamazaki, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Yusuke Nakatsu, Takako Kikuchi, Sunao Kaneko, Hirotoshi Tanaka, Tomoichiro Asano

“…Notably, these effects of SHBG were not altered by coaddition of large amounts of testosterone or estradiol. In conclusion, SHBG suppresses inflammation and lipid accumulation in macrophages and adipocytes, which might be among the mechanisms underlying the protective effect of SHBG, that is, its actions which reduce the incidence of metabolic syndrome.…”
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Krill oil ameliorates benign prostatic hyperplasia by regulating G1-phase cell cycle arrest and altering signaling pathways and benign prostatic hyperplasia-associated markers by Hoon Kim, Jongyeob Kim, Byungdoo Hwang, SangYong Park, Ji-Yeon Shin, EunByeol Go, Jae Sil Kim, Youngjin Roh, SoonChul Myung, Seok-Joong Yun, YungHyun Choi, Wun-Jae Kim, Sung-Kwon Moon

“…Furthermore, the administration of KO alleviated prostate size and weight and the cell layer thickness of prostate glands in a testosterone enanthate-induced BPH rat model. KO treatment altered the level of dihydrotestosterone in serum and the expression levels of BPH-related markers in prostate tissues. …”
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Post-treatment of rat aflatoxicosis by camel milk and silymarin by Nahla H. Hassaneen, Shabaan A. Hemeda, Abeer F. El Nahas, Ghadeer M. Albadrani, Muath Q. Al-Ghadi, Zuhair M. Mohammedsaleh, Sabreen E. Fadl, Eman M. El-Diasty, Hader I. Sakr, Hader I. Sakr

“…The evaluation was done through measuring leukocyte count, liver function tests, carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), ferritin, and testosterone. Moreover, the histopathology of the liver and testes was done along with expression levels of specific genes in the liver and testes.ResultsThe outcomes showed that the post-treatment with silymarin and camel milk improved biochemical markers in serum and ability to reproduce.ConclusionIn conclusion, post-treatment with camel milk and silymarin could mitigate the negative effect of AFB1 on rats.…”
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<i>Broussonetia papyrifera</i> Extract Can Be Used as a Raw Material Source for a Sterility Agent for <i>Microtus fortis</i> by Shuangye Wang, Tian Lan, Yunlin Zhao, Wanfu Liu, Tian Huang, Meiwen Zhang, Zhiyuan Hu, Zhenggang Xu

“…The results show that the growth of sex organs was inhibited, and the males’ testosterone levels and sperm quality were reduced. Though there were some positive effects on females, the reproductive parameters of coupled voles were inferior; the most treated couple exhibited an increased reproductive time, fetal counts, and reduced weight. …”
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Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses by Ye Ma, Fang Wu, Zeming Yu, Lu Yang

“…Furthermore, it was determined that the causal associations between these lipidome profiles and FRDs were independent of BMI, obesity, diabetes, smoking, alcohol use, physical activity, inflammation, depression, waist-hip ratio, vitamin D, dehydroepiandrosterone sulphate, sex hormone binding globulin, and testosterone levels. Most outcomes passed consistent tests without evidence of heterogeneity, pleiotropy, or reverse causality. …”
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The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages by Hui juan Zhu, Su juan Li, Hui Pan, Naishi Li, Dian xi Zhang, Lin jie Wang, Hong bo Yang, Qinyong Wu, Feng ying Gong

“…A total of 647 Chinese children and adolescents were recruited, and serum estradiol, testosterone, pituitary gonadotropins, leptin, and kisspeptin levels were measured. …”
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