Characterising SRD5A2 Gene Variants in 37 Indonesian Patients with 5-Alpha-Reductase Type 2 Deficiency by Nanis S. Marzuki, Firman P. Idris, Hannie D. Kartapradja, Alida R. Harahap, Jose R. L. Batubara

“…The 5-alpha-reductase type 2 deficiency (5ARD2) is an autosomal recessive condition associated with impairment in the conversion of testosterone to dihydrotestosterone. This condition leads to undervirilisation in 46,XY individuals. …”
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Effect of Donor Sperm on Quality of Life in Patients with Severe Oligoasthenosperm After ICSI Failure by Wang K, Xu Y, Qin N, Guo Y, Bai J, Li Z

“…The levels of serum total testosterone, reproductive quality of life, sleep quality and erectile function of the two groups were compared using the general data questionnaire, FertiQoL, Pittsburgh Sleep Quality Index (PSQI) and International erectile Function Index − 5(IIEF-5).Results: There was no significant difference in social demographic data and serum total testosterone level between the two groups after matching propensity score (P> 0.05). …”
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Modulation of hormonal, metabolic, inflammatory and oxidative stress biomarkers in women with polycystic ovary syndrome following combined (resistant and endurance) training: a ran... by Masoud Nasiri, Amirabbas Monazzami, Solmaz Alavimilani, Zatollah Asemi

“…Results After eight-week intervention in training group, insulin (P < 0.001), HOMA-IR (P < 0.001), total cholesterol (P < 0.001), LDL-cholesterol (P < 0.001), total testosterone (P < 0.001), AMH ( P = 0.02),MDA (P = 0.04) and FAI (P < 0.001) were significantly decreased, while QUICKI (P = 0.002) was remarkably increased compared with the control group. …”
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Revealing Sarcophyton extract's alleviating potential against gentamicin-induced renal and testicular toxicity in rat model by Nada S. Badr, Aml Talaat, Salwa A. El-Saidy, Aml Zaki Ahmed Ghoneim

“…Various parameters, including body weight, relative kidney and testes weight, differential white blood cell count, blood urea, creatinine, luteinizing hormone, testosterone, total antioxidant capacity, myeloperoxidase activity, and histopathological changes in kidney and testes tissue, were analyzed. …”
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Transient sex-related changes in the mice hypothalamo–pituitary–adrenal (HPA) axis during the acute phase of the inflammatory process by T. Daneva, E. Spinedi, R. Hadid, M.-C. Jacquier, M. Giacomini, R. C. Gaillard

“…The effect of LPS on plasma ACTH, corticosterone (B), testosterone and oestradiol (E) levels and on anterior pituitary (AP) ACTH and adrenal B contents at different times after treatment was studied. …”
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Effect of beetroot extract (beta vulgaris) against olanzapine on the pituitary, thyroid, and fertility in adult white male rats by Haleema Yousef ALNAHARY, Ghada L. TALEB, Naglaa Y. ABUZINADAH, Hanan Msaa AL JAMEI, Mariam ALGAMDI, Haneen Nasser AHMED, Hanan Abdulkarim SANGOUF, Anoud A. ALTHAGAFI

“…Thyroid-stimulating hormone (TSH), triiodothyronine (T3), tetraiodothyronine (T4), (T3/T4), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone levels were measured. The study found that beetroot extract treatment significantly increased thyroidstimulating hormone levels by 81% and TSH by 82% in the third and sixth weeks, while Triiodothyronine levels decreased by 42% and thyroxin levels by 115% in the third and sixth weeks, also, there was a significant decrease in testosterone levels in the group treated with Olanzapine by 108 % in the third week and by 116% in the sixth week when compared to a control group; additionally, the study found a 25% increase in absolute body weight in the beetroot extract group and 26% increase in a combined group treated with Olanzapine compared to Olanzapine. …”
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A more accurate relationship between serum androgen and metabolism among healthy, nonobese, reproductive-age women based on liquid chromatography-tandem mass spectrometry by Sha Ye, Yepei Huang, Yi Lu, Xiaoyan Li, Meiling Ye, Hongyu Lu, Junhua Shi, Jian Huang, Hong Cai

“…Liquid chromatography-tandem mass spectrometry was used to measure androgen indicators, including testosterone, sex hormone-binding globulin (SHBG), free testosterone (FT), dihydrotestosterone (DHT), androstenedione (A4), dehydroepiandrosterone (DHEA), and dehydroepiandrosterone sulfate (DHEAS). …”
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Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function by Abdullah A. Khawaji, Hossam S. El-Tholoth, Muath A. Albarakati, Bander A. Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami

“…Well-controlled diabetics had lower BMI (P = 0.001), higher free testosterone (FT) (P = 0.0002), lower sex hormone-binding globulin (SHBG) (P = 0.0001), and higher IIEF scores (P < 0.0001) compared to the poorly controlled group, indicating better erectile function and potential benefits of weight management and improved testosterone availability. …”
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Association of ultra-processed food-related metabolites with selected biochemical markers in the UK Biobank by Anthony Kityo, Byeonggeun Choi, Jung-Eun Lee, Chulho Kim, Sang-Ah Lee

“…Associations between UPF and UNPF-related metabolites, and serum C-reactive protein (CRP), insulin-like growth factor-1(IGF-1), sex hormone-binding globulin (SHBG), and testosterone were examined using multiple quantile regression. …”
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Use of Anabolic-Androgenic Steroids and Male Fertility: A Systematic Review and Meta-analysis by Prashant Motiram Mulawkar, Pankaj N. Maheshwari, Vineet Gauhar, Sumeet Gopal Agrawal, Taofiq Olayinka Mohammed, Abhishek Gajendra Singh, Gopal Ramdas Tak, Utsav Shailesh Shah, Deepali Parthsarthi Shukla, Deepali Mamankar

“…Objective: The objective of this study was to assess and systematically review the effects of AAS on male fertility parameters, spermiogram, testosterone, follicle-stimulating hormone (FSH) and luteinising hormone (LH) and to review reversibility and other morbidity impacting fertility. …”
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Pioglitazone Metformin Complex Improves Polycystic Ovary Syndrome Comorbid Psychological Distress via Inhibiting NLRP3 Inflammasome Activation: A Prospective Clinical Study by Qing-jun Guo, Jing Shan, Yi-feng Xu, Yan-yan Hu, Cui-lan Huo, Jing-yun Song, Chao-qun Wang, Hui Zhou, Chao-qin Yu, Qin Huang

“…PM was superior to metformin in reducing total testosterone (2.24±0.74 versus 3.06±0.83, p=0.024, at week 12).Conclusions. …”
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CD-1 mice females recognize male reproductive success via volatile organic compounds in urine by A. S. Khotskina, E. L. Zavjalov, E. P. Shnayder, L. A. Gerlinskaya, S. O. Maslennikova, D. V. Petrovskii, M. N. Baldin, A. L. Makas, V. M. Gruznov, M. L. Troshkov, M. P. Moshkin

“…The amplitude of peaks corresponding to this pheromone correlated with the testosterone level in blood and the weight of preputial glands. …”
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Pre-hormonal therapy combined with buccal mucosal graft for glans reconstruction in complete penile amputation: A case report and review of literature by Joko Pitoyo, Albert Ciam

“…Buccal mucosal grafting for neo-glans reconstruction, combined with testosterone pre-hormonal therapy, proved to be a simple procedure with satisfactory results. …”
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Cerebral Venous Sinus Thrombosis Linked to Dietary Supplement Use in a Bodybuilder: A Case Report by Sondos K. Khalil, Zahra B. Yousif, Jawaher Baraka, Israa Al‐Hashimi, Moaz O. Moursi, Abdalla Fadul, Wanis Ibrahim

“…ABSTRACT Many dietary supplements commonly used by bodybuilders and athletes carry thrombogenic risks, potentially leading to life‐threatening conditions like arterial and venous thrombosis by either elevating testosterone levels or directly interfering with homeostasis. …”
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Electroporation assisted delivery of Roussin salt porphyrin-based conjugated carbon nanoparticles for sono–X-ray–photodynamic prostate cancer in vitro and in vivo treatment by Samir Ali Abd El-Kaream, Abed Elrahman Ahmad Mohamad, Sohier Mahmoud El-Kholey, Samia Abd El-Moniem Ebied

“…Materials and methods Human PCa cells (DU-145) were used in the in vitro study, and the in vivo application groups of the study protocol were Swiss albino mice treated with N-methyl-N-nitrosourea (MNU) / testosterone only; they were not given any treatment to induce PCa. …”
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Heart rate cost as a tool for monitoring recovery between acute training sessions by José Morais Souto Filho, Milton Rocha de Moraes, Patrício Lopes de Araújo Leite, Larissa Alves Maciel, Andréa Cândida Arruda Andrade Rezende, Thiago dos Santos Rosa, Fabiana Andrade Machado, Sergio Rodrigues Moreira, Ricardo Yukio Assano, Marcelo Magalhães Sales, Herbert Gustavo Simões

“…No significant changes were found in the testosterone/cortisol ratio or HRV (HRV) ( p > 0.05), likely due to the fact that these variables reflect chronic stress more than acute stress. …”
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Successful Multimodal Management of an Aggressive Functional Gonadotropic Pituitary Macroadenoma by Jeffrey J. Feng, MS, Sophie M. Cannon, MD, Stephanie K. Cheok, MD, Mark S. Shiroishi, MD, Kyle M. Hurth, MD, PhD, Anna J. Mathew, MD, Gabriel Zada, MD, John D. Carmichael, MD

“…Postoperatively, the patient’s FSH level decreased, whereas the LH level normalized within 1 week. The free testosterone level normalized at 9 months. The patient underwent radiotherapy for a small amount of residual tumor in the right cavernous sinus and has demonstrated no evidence of disease or hormonal progression. …”
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Kallmann Syndrome. Case presentation by Elodia Rivas Alpízar, Maidelín Garcés Saborit, Caridad Hernández Gutiérrez, Odalis Yanes Izray

“…A cytogenetic hormonal study (FSH; LH, testosterone) was developed, a nuclear MRI of the skull and silla turca in which it was confirmed agenesis of the right olfactory bulb and hypoplastic of the left one. …”
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Rifampicin for Treatment of Cholestatic Pruritus Caused by Drug-Induced Acute Liver Injury as Assessed by the RUCAM Classification by Ali R. Ahmadi, Maria Chicco, Marcel van den Berge

“…The patient was diagnosed with drug-induced acute liver injury and secondary acute renal failure most likely caused by testosterone purchased on the black market. The pruritus caused insomnia and significant psychological distress. …”
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Micropenis by Jeremy Wiygul, Lane S. Palmer

“…Management revolves around testosterone (direct administration or encouraging the patient's body to make its own), and long-term results with respect to increase in penile length are promising. …”
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