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59281
Mechanism of Electroacupuncture at Baihui and Shenting Alleviating Cerebral Ischemia-reperfusion Injury via Regulating BNIP3L-Mediated Mitophagy
Published 2022-02-01“…After 7 days of intervention, the left cerebral cortex tissue of each group was obtained, hematoxylin-eosin (HE) staining was used to observe the pathological changes of the brain tissue, the expression level of LC3-Ⅱ/LC3-Ⅰ protein was detected by Western blot, and the tissue immunofluorescence technology was applied to detect the expression and colocalization of mitophagy-related protein BNIP3L and SQSTM1 labeled. …”
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UK cancer vaccine advance – Recognising and realising opportunities
Published 2025-01-01“…Emphasising partnership and proactive strategies, this article outlines the ambition to harness national and local system capabilities in the UK; to work in collaboration with potential pharmaceutic partners; and to seize the opportunity to deliver the pace for rapid advances in cancer vaccine technology.…”
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Creation of body color mutants by CRISPR/Cas9 gene editing in largemouth bass, Micropterus salmoides
Published 2025-03-01“…It is the first successful application of gene-editing technology in LMB, which has taken a key step in studying the gene function and molecular mechanism and provided a novel method for improving the economic traits of LMB aquaculture.…”
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59288
Torrefaction of bamboo pellets using a fixed counterflow multibaffle reactor for renewable energy applications
Published 2024-01-01“…This study aims to investigate the properties and viability of torrefied G. pseudoarundinacea pellets for solid fuel applications to fill existing knowledge gaps about this technology’s potential.METHODS: A fixed counter-flow multi-baffle reactor was used to torrefy G. pseudoarundinacea bamboo pellets. …”
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GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma
Published 2021-09-01“…We used flow cytometry, coimmunoprecipitation, RNA sequencing, mass spectrum, chromatin immunoprecipitation and Gdf15–/–, OT-I and GFP transgenic mice to demonstrate the effects of GDF15 on Treg cells and related molecular mechanism. We used hybridoma technology to generate monoclonal antibody to block GDF15 and evaluate its effects on HCC-associated immunosuppression.Results GDF15 is positively associated with the elevation of Treg cell frequencies in patients wih HCC. …”
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Time Zero for Net Zero: A Coal Mine Baseline for Decarbonising Heat
Published 2022-12-01“…However, mined environments are highly complex and we currently lack the understanding to confidently enable a widespread, cost-effective deployment of the technology. Extensive and repeated use of the mined subsurface as a thermal source/store and the optimisation of operational infrastructure encompasses a range of scientific and technical challenges that require broad partnerships to address. …”
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Local application of sodium thiosulfate as an otoprotectant for cisplatin-exposed patients – A narrative literature review to explore the potential benefit for children with cancer...
Published 2025-06-01“…The burden and potential sequalae of repeated intratympanic procedures in children, together with the low level of evidence of efficacy, currently limited to pre-clinical data, suggests that further study and potentially improved technology to apply local STS is required for childhood cancer patients receiving cisplatin.…”
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Sex determination and acclimation response of dwarf snakehead fish Channa limbata from West Java
Published 2024-08-01“…This study aims to evaluate the acclimation response of wild-type dwarf snakehead fish in captivity and its sexual characteristics as a basis for domestication and hatchery technology. The fish samples used were natural catches from rivers in West Java measuring <100 mm to >150 mm of body length then individually acclimated indoors in an aquarium (35×20×20 cm) for 14 days. …”
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