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RNA‐Binding Protein Hnrnpa1 Triggers Daughter Cardiomyocyte Formation by Promoting Cardiomyocyte Dedifferentiation and Cell Cycle Activity in a Post‐Transcriptional Manner
Published 2025-01-01“…In contrast, CRISPR/Cas9 technology is used to generate CM‐specific Hnrnpa1 knockout mice. …”
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Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context
Published 2025-02-01“…Funding: This study was supported by The National Natural Science Foundation of China (No. 82425101); Beijing Municipal Science & Technology Commission (No. Z231100004823036); Capital's Funds for Health Improvement and Research (2022-2-2045); National Key Research & Development Program of China (2022YFF1501500, 2022YFF1501501, 2022YFF1501502, 2022YFF1501503, 2022YFF1501504, 2022YFF1501505).…”
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Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling
Published 2025-01-01“…Zihe Zhao,1,* Taicai Chen,2,3,* Qingyuan Liu,4 Jianhang Hu,1 Tong Ling,2,3 Yuanhao Tong,5 Yuexue Han,1 Zhengyang Zhu,6 Jianfeng Duan,7 Yi Jin,1 Dongsheng Fu,1 Yuzhu Wang,1 Chaohui Pan,1 Reyaguli Keyoumu,1 Lili Sun,1 Wendong Li,1 Xia Gao,8,9 Yinghuan Shi,2,3 Huan Dou,10,11 Zhao Liu1 1Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 2The State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing, People’s Republic of China; 3National Institute of Healthcare Data Science, Nanjing University, Nanjing, People’s Republic of China; 4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Department of Thoracic Surgery, BenQ Medical Center, Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 6Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 7Department of Critical Care Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 8Department of Otolaryngology, Head and Neck Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 9Jiangsu Provincial Key Medical Discipline (Laboratory), Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 10The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, People’s Republic of China; 11Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhao Liu, Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, #321 Zhongshan Road, Nanjing, 210008, People’s Republic of China, Email liuzhao@nju.edu.cn Huan Dou, The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, People’s Republic of China, Email douhuan@nju.edu.cnPurpose: Stanford Type B Aortic Dissection (TBAD), a critical aortic disease, has exhibited stable mortality rates over the past decade. …”
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Effect of UV-C Postharvest Disinfection on the Quality of Fresh-Cut 'Tommy Atkins' Mango
Published 2023-02-01“…Ultraviolet short wave (UV-C) is an alternative technology for fresh-cut products that leads to microbial inactivation and the increase of beneficial compounds. …”
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Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
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Identification and Spatial Mapping of Locality of Streetscapes in Shanghai Hengfu Historic and Cultural Preservation Area
Published 2025-02-01“…These indicators are then compared with streetscape characteristics that can be measured by current image analysis technologies. On this basis, a framework for identification of streetscape locality is constructed. …”
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Development, implementation, and evaluation of an innovative clinical trial operations training program for Africa (ClinOps)
Published 2025-01-01“…End-course evaluations gathered feedback on the course content, organization, technology, and instructional methods. We used Wilcoxon rank test to analyze pre- and post-survey scores and thematic analysis to analyze the qualitative data. …”
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Association of blood cadmium and physical activity with mortality: A prospective cohort study
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Elucidating the pharmacological foundations and mechanisms of the Sihai Shuyu formula in treating Graves’ disease through integrated serum metabolomics and network pharmacology wit...
Published 2025-01-01“…Ethnopharmacological relevanceThe Sihai Shuyu Formula (SHSY) shows promising potential for treating Graves’ disease (GD), although the therapeutic mechanisms and pharmacological basis of SHSY have not been thoroughly evaluated.ObjectiveThis work is aim to investigate the pharmacological basis and mechanism of SHSY in the treatment of GD by integrating non-targeted serum metabolomics and network pharmacology coupled with molecular docking technology.Materials and methodsGD was induced in mice through injections of Ad-TSH289. …”
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European Guideline on IgG4-related Digestive Disease — UEG and SGF Evidence-based Recommendations
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