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Dynamic changes and future trend predictions of the global burden of anxiety disorders: analysis of 204 countries and regions from 1990 to 2021 and the impact of the COVID-19 pande...
Published 2025-01-01“…Funding: Jilin Province 2023 Health Science and Technology Capability Enhancement Plan Project (2023LC024) and Jilin Provincial Department of Science and Technology project (20230203054SF). …”
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Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugatesResearch in context
Published 2025-02-01“…Funding: This study was supported by the Japan Society for the Promotion of Science, the Japan Agency for Medical Research and Development, Japan Science and Technology Agency, and the Osaka Medical Research Foundation for Intractable Diseases.…”
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Revealing the biological features of the axolotl pancreas as a new research model
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miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma
Published 2025-01-01“…In this study, we identify miRNAs impacting FN-RMS cell identity, revealing miR-449a and miR-340 as major regulators of the cell cycle and p53 signaling. Through miR-eCLIP technology, we demonstrate that miR-449a and miR-340 directly target transcripts involved in glycolysis and mitochondrial pyruvate transport, inhibiting the mitochondrial pyruvate carrier (MPC) complex. …”
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MSA-3D: Metallicity Gradients in Galaxies at z ∼ 1 with JWST/NIRSpec Slit-stepping Spectroscopy
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Integrated Framework and Technical Path for Multi-level Nested Assessment of Landscape Character
Published 2025-01-01“…In addition, combining the integrated framework with digital technology analysis, a landscape character assessment approach that adapts to multi-scale practical needs is proposed, providing a technical path for analyzing the local characteristics of landscape based on different levels of landscape space. …”
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Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy
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