Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer’s disease stages by Giacomo Siano, Giacomo Siano, Martina Varisco, Marco Terrigno, Congwei Wang, Arianna Scarlatti, Vincenzo Iannone, Marco Groth, Marie-Christine Galas, Jeroen J. M. Hoozemans, Alessandro Cellerino, Alessandro Cellerino, Antonino Cattaneo, Cristina Di Primio

Subjects: “…tau…”
Get full text

Comparison of New Tau PET-Tracer Candidates With [F]T808 and [F]T807 by Lieven Declercq Pharmacist, Sofie Celen PhD, Joan Lecina PhD, Muneer Ahamed PhD, Thomas Tousseyn Prof, MD, PhD, Diederik Moechars PhD, Jesus Alcazar PhD, Manuela Ariza PhD, Katleen Fierens PhD, Astrid Bottelbergs PhD, Jonas Mariën PhD, Rik Vandenberghe Prof, MD, PhD, Ignacio Jose Andres PhD, Koen Van Laere Prof, MD, PhD, Alfons Verbruggen Prof, PhD, Guy Bormans Prof, PhD

“…Early clinical results of two tau tracers, [ 18 F]T808 and [ 18 F]T807, have recently been reported. …”
Get full text

CP violation in two-meson Tau decays induced by heavy new physics by Daniel A. López Aguilar, Javier Rendón, Pablo Roig

“…Abstract We apply the effective field theory formalism that was used to study CP violation induced by heavy new physics in the τ → K S πν τ decays to the other two-meson tau decay channels. We focus on the rate and the forward-backward asymmetries, that are predicted using current bounds on the complex Wilson coefficients of the effective Lagrangian. …”
Get full text

Erratum to: Probing the mixing between sterile and tau neutrinos in the SHiP experiment by Ki-Young Choi, Sung Hyun Kim, Yeong Gyun Kim, Kang Young Lee, Kyong Sei Lee, Byung Do Park, Jong Yoon Sohn, Seong Moon Yoo, Chun Sil Yoon

Get full text

The MIR-NAT MAPT-AS1 does not regulate Tau expression in human neurons by Rafaela Policarpo, Leen Wolfs, Saul Martínez-Montero, Lina Vandermeulen, Ines Royaux, Gert Van Peer, Pieter Mestdagh, Bart De Strooper, Annerieke Sierksma, Constantin d’Ydewalle

Get full text

Interplay of p23 with FKBP51 and their chaperone complex in regulating tau aggregation by Pijush Chakraborty, Markus Zweckstetter

“…Abstract The pathological deposition of tau and amyloid-beta into insoluble amyloid fibrils are pathological hallmarks of Alzheimer’s disease. …”
Get full text

Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

Subjects: “…Tau oligomers…”
Get full text

Eagle Nesting Groups in the Important Bird Area “Donyz-Tau cliff faces” in 2022 by Ilya E. Smelansky, Andrey A. Tomilenko, Anna N. Barashkova, Roman N. Alexandrovich

“…The Important Bird Area (IBA) “Donyz-Tau cliff faces” (KZ019), with an area of 387,110 hectares, has been allocated by I.V. …”
Get full text

Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool by Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, Akito Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki Yoshimura, Gen Matsumoto, Hiroko Bannai

“…Tauopathy is a spectrum of diseases characterized by fibrillary tau aggregate formation in neurons and glial cells in the brain. …”
Get full text

Generalized third-kind Chebyshev tau approach for treating the time fractional cable problem by Waleed Mohamed Abd-Elhameed, Omar Mazen Alqubori, Abdulrahman Khalid Al-Harbi, Mohammed H. Alharbi, Ahmed Gamal Atta

“…This work introduces a computational method for solving the time-fractional cable equation (TFCE). We utilize the tau method for the numerical treatment of the TFCE, using generalized Chebyshev polynomials of the third kind (GCPs3) as basis functions. …”
Get full text

Immunoassay detection of multiphosphorylated tau proteoforms as cerebrospinal fluid and plasma Alzheimer’s disease biomarkers by Anna L. Wojdała, Giovanni Bellomo, Lorenzo Gaetani, Charlotte E. Teunissen, Lucilla Parnetti, Davide Chiasserini

“…Abstract Different forms of phosphorylated tau (p-tau) have shown strong potential as Alzheimer’s disease (AD) biomarkers in both cerebrospinal fluid (CSF) and plasma. …”
Get full text

Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities by Filippa Lo Cascio, Suhyeorn Park, Urmi Sengupta, Nicha Puangmalai, Nemil Bhatt, Nikita Shchankin, Cynthia Jerez, Naomi Moreno, Alice Bittar, Rhea Xavier, Yingxin Zhao, Cankun Wang, Hongjun Fu, Qin Ma, Mauro Montalbano, Rakez Kayed

“…Tau oligomers are suggested to be the primary neurotoxic species that initiate aggregation and propagate prion-like structures. …”
Get full text

Understanding retinal tau pathology through functional 2D and 3D iPSC-derived in vitro retinal models by Lorenza Mautone, Federica Cordella, Alessandro Soloperto, Silvia Ghirga, Giorgia Di Gennaro, Ylenia Gigante, Silvia Di Angelantonio

Subjects: Get full text

ViTAU: Facial paralysis recognition and analysis based on vision transformer and facial action units by Jia GAO, Wenhao CAI, Junli ZHAO, Fuqing DUAN

Get full text

Study of Salidroside on Expression of Synaptophysin and Tau in Rats after Local Cerebral Ischemia-reperfusion Injury by Yanqing SU, Yingzheng WANG, Xuwen WANG, Baiying SONG, Yu LIN, Guizhu HONG

Subjects: Get full text

Memantine Differentially Regulates Tau Phosphorylation Induced by Chronic Restraint Stress of Varying Duration in Mice by Yunsheng Liu, Lan Cao, Xiaoxu Zhang, Yan Liang, Yuxia Xu, Cuiqing Zhu

“…Exposure to chronic psychiatric stress has been linked to Alzheimer’s disease-related tau hyperphosphorylation and abnormalities in glutamate neurotransmission. …”
Get full text

Iron(ing) out parkinsonisms: The interplay of proteinopathy and ferroptosis in Parkinson's disease and tau-related parkinsonisms by Maria João da Costa Caiado, Amalia M. Dolga, Wilfred F.A. den Dunnen

“…Thus, we explore the current findings relating to the relationship of parkinsonism proteinopathy (α-synuclein in PD, and tau in PSP/CBD) paralleled to a specific form of cell death, ferroptosis. …”
Get full text

Cerebrospinal fluid cyclase-associated protein 2 is increased in Alzheimer’s disease and correlates with tau pathology by Alessandro Padovani, Andrea Pilotto, Silvia Pelucchi, Laura D’Andrea, Ramona Stringhi, Federica Gorla, Bahar Aksan, Salvatore Caratozzolo, Alberto Benussi, Alice Galli, Clara Tirloni, Daniela Mauceri, Antonio Canale, Silvana Archetti, Barbara Borroni, Monica Di Luca, Elena Marcello

Get full text

Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation. by Michael O Isei, Meredith Crockett, Emily Chen, Joel Rodwell-Bullock, Trae Carroll, Peter A Girardi, Keith Nehrke, Gail V W Johnson

“…In Alzheimer's disease, abnormal tau phosphorylation disrupts mitophagy, a quality control process through which damaged organelles are selectively removed from the mitochondrial network. …”
Get full text

Rotation errors in path integration are associated with Alzheimer’s disease tau pathology: a cross-sectional study by Lise Colmant, Lisa Quenon, Lara Huyghe, Adrian Ivanoiu, Thomas Gérard, Renaud Lhommel, Pauline Coppens, Yasmine Salman, Vincent Malotaux, Laurence Dricot, Lukas Kunz, Nikolai Axmacher, Philippe Lefèvre, Bernard Hanseeuw

Subjects: Get full text