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  1. 421

    Socio-economic assessment of drought impacts in Lesotho: implications for early action by Relebohile Agnes Mojaki, Makoala Vitalis Marake, Evan Easton-Calabria, Joalane Rethabile Marunye, Erin Coughlan de Perez

    Published 2024-11-01
    “…Informants also perceived the following actions could be taken before a drought is manifested: clear agro-climatological early warning messages, tailor-made drought-relevant advisories, water harvesting and availability of drought-tolerant seeds. …”
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  2. 422
  3. 423

    Effect of static magnetic field on microstructure and mechanical property of AlSi10Mg alloy by laser directed energy deposition by Weiming Niu, Bingke Song, Jiasen Han, Haiou Yang, Zhaopu Yao, Hui Chen, Xin Lin

    Published 2025-01-01
    “…This work uses an infrared laser with a wavelength of 960 nm to conduct the LDED process of AlSi10Mg alloy, where magnetic field with various intensities is employed to tailor the macroscopic morphology, microstructure and mechanical properties of the processed sample. …”
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  4. 424

    The Role of von Willebrand Factor in Vascular Inflammation: From Pathogenesis to Targeted Therapy by Felice Gragnano, Simona Sperlongano, Enrica Golia, Francesco Natale, Renatomaria Bianchi, Mario Crisci, Fabio Fimiani, Ivana Pariggiano, Vincenzo Diana, Andreina Carbone, Arturo Cesaro, Claudia Concilio, Giuseppe Limongelli, Mariagiovanna Russo, Paolo Calabrò

    Published 2017-01-01
    “…Several lines of research have recently investigated “tailor-made” inhibitors of VWF. Results from animal models and clinical studies support the potent anti-inflammatory and antithrombotic effect of VWF antagonism, providing reassuring data on its safety profile. …”
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    Article
  5. 425

    Investigating Falls Risk Awareness in Hospitals Using the Self‐Awareness of Falls Risk Measure (SAFRM): Empirical Research Quantitative by Elissa Dabkowski, Simon J. Cooper, Jhodie Duncan, Karen Missen

    Published 2025-01-01
    “…The SAFRM facilitates a person‐centred approach to falls prevention by providing opportunities for the clinician to collaborate with the patient and tailor fall prevention strategies. Impact Problem: Inpatient falls in hospital settings. …”
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    Article
  6. 426

    The association between stress-induced hyperglycemia ratio and cardiovascular events as well as all-cause mortality in patients with chronic kidney disease and diabetic nephropathy by Boning Cao, Zhendong Guo, Dan-Ting Li, Le-Ying Zhao, Zhen Wang, Ya-Bin Gao, Yao-Xian Wang

    Published 2025-02-01
    “…SHR may serve as a critical biomarker for prognostic assessment in these populations, enabling clinicians to identify high-risk patients and tailor personalized treatment strategies that enhance patient quality of life and mitigate mortality risk. …”
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    Article
  7. 427

    Empowering personalized oncology: evolution of digital support and visualization tools for molecular tumor boards by Cosima Strantz, Dominik Böhm, Thomas Ganslandt, Melanie Börries, Patrick Metzger, Thomas Pauli, Andreas Blaumeiser, Alexander Scheiter, Ian-Christopher Jung, Jan Christoph, Iryna Manuilova, Konstantin Strauch, Arsenij Ustjanzew, Niklas Reimer, Hauke Busch, Philipp Unberath

    Published 2025-01-01
    “…Abstract Background Molecular tumor boards (MTBs) play a pivotal role in personalized oncology, leveraging complex data sets to tailor therapy for cancer patients. The integration of digital support and visualization tools is essential in this rapidly evolving field facing fast-growing data and changing clinical processes. …”
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    Article
  8. 428

    New clinical insights into the treatment of benign uretero‐ileal anastomotic stricture following radical cystectomy and urinary diversion by Yixuan Mou, Cenchao Yao, Zhenghong Liu, Pu Zhang, Xiaolong Qi, Dahong Zhang, Yiyang Chen, Weiwen Yu, Shuai Wang

    Published 2024-09-01
    “…To preserve residual renal function and improve prognosis, it is crucial to derive insights from experience and tailor individualized treatment strategies for different patients. …”
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    Article
  9. 429

    Efficacy and safety of PD-1/PD-L1 inhibitors in advanced or recurrent endometrial cancer: a meta-analysis with trial sequential analysis of randomized controlled trials by Ji Ren, Jinghe Wang, Yanan Wang, Dongying Yang, Jianming Sheng, Shili Zhu, Yunli Liu, Xiaoqi Li, Wei Liu, Binbin Zhang

    Published 2025-01-01
    “…Although there was no observed difference in the incidence of any grades AEs (RR = 0.994, 95% CI: 0.982-1.006; 95% PI: 0.978-1.009), the risk of grade ≥ 3 AEs was elevated in the group receiving PD-1/PD-L1 inhibitors in combination with CT (RR = 1.132, 95% CI: 1.023-1.252; 95% PI: 0.836-1.532).ConclusionThe combination of PD-1/PD-L1 inhibitors with CT significantly improved PFS and OS in advanced or recurrent EC patients, with particularly pronounced benefits observed in those with dMMR. Clinicians can tailor treatment strategies according to individual patient characteristics to optimize therapeutic outcomes, while remaining alert to the possibility of AEs in clinical practice.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024595455.…”
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  10. 430

    Modulating the fatty acid composition of black soldier fly larvae via substrate fermentation by F. IJdema, S. Lievens, R. Smets, G. Poma, M. Van Der Borght, B. Lievens, J. De Smet

    Published 2025-01-01
    “…Therefore, these results suggest that BSFL with tailor-made FA profiles for a specific application could be successfully produced.…”
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  11. 431

    Hormonal Contraception and Bone Metabolism: Emerging Evidence from a Systematic Review and Meta-Analysis of Studies on Post-Pubertal and Reproductive-Age Women by Alice Tassi, Ambrogio P Londero, Anjeza Xholli, Giulia Lanzolla, Serena Bertozzi, Luca Savelli, Federico Prefumo, Angelo Cagnacci

    Published 2025-01-01
    “…These findings would potentially influence decisions relevant to CHC prescriptions during a woman’s reproductive phases, emphasizing the need for additional research to tailor CHC usage to bone health.…”
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  12. 432
  13. 433

    Medication related osteonecrosis (MRONJ) in the management of CTIBL in breast and prostate cancer patients. Joint report by SIPMO AND SIOMMMS by Francesco Bertoldo, Cristina Eller-Vainicher, Vittorio Fusco, Rodolfo Mauceri, Jessica Pepe, Alberto Bedogni, Andrea Palermo, Umberto Romeo, Giuseppe Guglielmi, Giuseppina Campisi

    Published 2025-02-01
    “…Conclusions: Despite obvious weaknesses of the available international literature, the Expert Panel recognized the need to tailor separate MRONJ preventive approach for breast and prostate cancer patients on adjuvant endocrine therapy who begin low-dose BMA therapy to prevent CTIBL and provided this practical guidance for bone specialists and oral healthcare providers. …”
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    Article
  14. 434

    Physics-Informed Neural Networks for Modal Wave Field Predictions in 3D Room Acoustics by Stefan Schoder

    Published 2025-01-01
    “…Different methods like hyperparameter optimization, adaptive refinement, Fourier feature engineering, and locally adaptive activation functions with slope recovery are tested to tailor the PINN’s accuracy to an experimentally validated finite element analysis reference solution computed with openCFS. …”
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  15. 435

    Personality and help-seeking for psychological distress: a systematic review and meta-analysis by Anna Szücs, Anna Szücs, Anna Szücs, Rachel Hui Xin Lam, Wymann Shao Wen Tang, Lifan Zhou, Monica Lazarus, Andrea B. Maier, Andrea B. Maier, Andrea B. Maier, Jose M. Valderas, Jose M. Valderas, Jose M. Valderas

    Published 2025-01-01
    “…Understanding which personality traits relate to help-seeking can help better tailor mental healthcare to individual needs. However, findings regarding associations of personality traits with help-seeking have been inconsistent.MethodsThis systematic review and meta-analysis focused on English-language research studies on the association of personality (encompassing personality disorders, Five Factor –Big Five– dimensions, and other measures of personality) with depression, anxiety, or unspecified psychological distress in adults aged 18 years and older. …”
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  16. 436

    Cartilage structure-inspired nanofiber-hydrogel composite with robust proliferation and stable chondral lineage-specific differentiation function to orchestrate cartilage regenerat... by Yaqiang Li, Xiaowei Xun, Liang Duan, Erji Gao, Jiaxin Li, Lei Lin, Xinping Li, Aijuan He, Haiyong Ao, Yong Xu, Huitang Xia

    Published 2025-05-01
    “…By encapsulating chondrocytes within the biomaterial system, mature neo-cartilage tissues with typical cartilage lacunae structures and abundant homogeneous cartilage-specific ECM deposition were successfully regenerated in vitro and in vivo. Furthermore, with a tailor-made growth factor-releasing strategy, the biomaterial system with low cell seeding density achieved biochemically and biomechanically functional neo-cartilage tissue regeneration, comparable to that achieved with high cell seeding density in the nanofiber-hydrogel composite. …”
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  17. 437
  18. 438

    Pharmacological management of gambling disorder: A systematic review and network meta-analysis by Konstantinos Ioannidis, Cinzia Del Giovane, Charidimos Tzagarakis, Jeremy E. Solly, Samuel J. Westwood, Valeria Parlatini, Henrietta Bowden-Jones, Jon E. Grant, Samuele Cortese, Samuel R. Chamberlain

    Published 2025-02-01
    “…Further clinical trials of novel compounds, and analysis of individual participant data are needed, to strengthen the evidence base, and help tailor treatments at the individual patient level.…”
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  19. 439
  20. 440

    Talking with pregnant women exposed to cannabis use after cannabis legalization: Experiences of professionals working in Québec's social and healthcare system by Karen A. Dominguez-Cancino, Rose Chabot, Yolaine Frossard de Saugy, Kristelle Alunni-Menichini, Lysiane Robidoux-Léonard, Genève Guilbert-Gauthier, Karine Bertrand, Christophe Huỳnh, Pablo Martínez, Helen-Maria Vasiliadis, Nadia L'Espérance, Victoria Massamba, Julie Loslier, José Ignacio Nazif-Munoz

    Published 2025-06-01
    “…Two key processes—i) exploration and assessment, and ii) action—were identified. Professionals tailor interventions, including counseling, psycho-emotional management, harm reduction, and referrals, based on risk levels and willingness to change. …”
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