Outcomes with bridging radiation therapy prior to chimeric antigen receptor T-cell therapy in patients with aggressive large B-cell lymphomas by Gohar S. Manzar, Chelsea C. Pinnix, Stephanie O. Dudzinski, Kathryn E. Marqueen, Elaine E. Cha, Lewis F. Nasr, Alison K. Yoder, Michael K. Rooney, Paolo Strati, Sairah Ahmed, Chijioke Nze, Ranjit Nair, Luis E. Fayad, Michael Wang, Loretta J. Nastoupil, Jason R. Westin, Christopher R. Flowers, Sattva S. Neelapu, Jillian R. Gunther, Bouthaina S. Dabaja, Susan Y. Wu, Penny Q. Fang

“…Comprehensive bRT alone to all disease sites was delivered to 51% of patients, and 29.4% were additionally bridged with systemic therapy. Median follow-up was 10.3 months (95% CI: 7.7-16.4). …”
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Carbon stock dynamics of forest to oil palm plantation conversion for ecosystem rehabilitation planning by D. Frianto, E. Sutrisno, A. Wahyudi, E. Novriyanti, W.C. Adinugroho, A.S. Yunianto, H. Kurniawan, H. Khotimah, A. Windyoningrum, I.W.S. Dharmawan, H.L. Tata, S. Suharti, H.H. Rachmat, E.M. Lim

“…This study investigated the fluctuations in carbon stock caused by these alterations and provides valuable perspectives on the potential of agroforestry systems to promote a wider range of land uses. Additionally, it highlights their role in ecosystem restoration initiatives and the better management of forest peatland regions.METHODS: A spatial analysis was conducted on Landsat 5 and 8 satellite images by using shapefile data stored within the Google Earth Engine platform. …”
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Second-line treatment patterns and outcomes in advanced HCC after progression on atezolizumab/bevacizumab by Meng Wu, Claudia A.M. Fulgenzi, Antonio D’Alessio, Alessio Cortellini, Ciro Celsa, Giulia F. Manfredi, Bernardo Stefanini, Y. Linda Wu, Yi-Hsiang Huang, Anwaar Saeed, Angelo Pirozzi, Tiziana Pressiani, Lorenza Rimassa, Martin Schoenlein, Kornelius Schulze, Johann von Felden, Yehia Mohamed, Ahmed O. Kaseb, Arndt Vogel, Natascha Roehlen, Marianna Silletta, Naoshi Nishida, Masatoshi Kudo, Caterina Vivaldi, Lorenz Balcar, Bernhard Scheiner, Matthias Pinter, Amit G. Singal, Joshua Glover, Susanna Ulahannan, Fredrich Foerster, Arndt Weinmann, Peter R. Galle, Neehar D. Parikh, Wei-Fan Hsu, Alessandro Parisi, Hong Jae Chon, David J. Pinato, Celina Ang

“…Results: A total of 406 patients alive after progression on first-line A/B were included in the final analysis, of whom 45.3% (n = 184) received best supportive treatment (BST) and 54.7% (n = 222) continued active systemic treatment. In the second line, 155 patients were treated with tyrosine kinase inhibitors (TKIs), 45 with immune checkpoint inhibitor (IO)-based regimens, and 3 had missing data. …”
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Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis by Maria Papathanasiou, Aiste‐Monika Jakstaite, Sara Oubari, Johannes Siebermair, Reza Wakili, Julia Hoffmann, Alexander Carpinteiro, Tim Hagenacker, Andreas Thimm, Christoph Rischpler, Lukas Kessler, Tienush Rassaf, Peter Luedike

“…CA staging was based on established biomarker systems. Binomial logistic regression was run to analyse the effects of clinical variables on the likelihood of AF. …”
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Development and validation of a machine learning-based model to predict survival in patients with cirrhosis after transjugular intrahepatic portosystemic shuntResearch in context by Binlin Da, Huan Chen, Wei Wu, Wuhua Guo, Anru Zhou, Qin Yin, Jun Gao, Junhui Chen, Jiangqiang Xiao, Lei Wang, Ming Zhang, Yuzheng Zhuge, Feng Zhang

“…The RF model outperformed other scoring systems, such as the (Child-Turcotte-Pugh score) CTP, (model for end-stage liver disease) MELD, (sodium MELD) MELD-Na, (Freiburg index of post-TIPS survival) FIPS and (Albumin-Bilirubin) ALBI, showing the highest (area under the curve) AUC of 0.82 (95% CI: 0.72, 0.91) and 0.7 (95% CI: 0.60, 0.79) in predicting 1-year survival across the testing set and external validation cohort. …”
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Design, evaluation, and future projections of the NARCliM2.0 CORDEX-CMIP6 Australasia regional climate ensemble by G. Di Virgilio, G. Di Virgilio, J. P. Evans, J. P. Evans, F. Ji, F. Ji, E. Tam, J. Kala, J. Andrys, C. Thomas, D. Choudhury, C. Rocha, S. White, Y. Li, M. El Rafei, R. Goyal, M. L. Riley, J. Lingala

“…NARCliM2.0 is a valuable resource for assessing climate change impacts on societies and natural systems and informing resilience planning by reducing model biases versus earlier NARCliM generations and providing more up-to-date future climate projections utilising CMIP6.…”
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Unveiling genetic basis of seedling emergence from deep soil depth under dry direct- seeded conditions in rice (Oryza sativa L.) by Vagish Mishra, Vagish Mishra, Shilpi Dixit, Shilpi Dixit, Swati Tyagi, Swati Tyagi, Challa Venkateswarlu, Challa Venkateswarlu, Pronob J. Paul, Pronob J. Paul, Anoop Kishor Singh Gurjar, Anoop Kishor Singh Gurjar, Shalabh Dixit, Nitika Sandhu, Smita Kurup, Arvind Kumar, Arvind Kumar, Pallavi Sinha, Pallavi Sinha, Vikas Kumar Singh, Vikas Kumar Singh, Uma Maheshwar Singh, Uma Maheshwar Singh

“…The identified QTLs, genes, and breeding lines from this study provide valuable resources for developing rice varieties with enhanced tolerance to deep soil emergence, making them well-suited for mechanized DSR systems.…”
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Annexin A8 deficiency delays atherosclerosis progression by Carmen Gutiérrez‐Muñoz, Rafael Blázquez‐Serra, Irene San Sebastian‐Jaraba, Sandra Sanz‐Andrea, Maria J. Fernández‐Gómez, Gonzalo Nuñez‐Moreno, Pablo Mínguez, Joan Carles Escolá‐Gil, Paula Nogales, Veronique Ollivier, Jose L. Martín‐Ventura, Benoit Ho‐Tin Noe, Ursula Rescher, Nerea Méndez‐Barbero, Luis M. Blanco‐Colio

“…ApoE−/− mice lacking systemic AnxA8 (ApoE−/−AnxA8−/−) were generated to assess the effect of AnxA8 deficiency on atherosclerosis. …”
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Lentivirus‐mediated gene therapy for Fabry disease: 5‐year End‐of‐Study results from the Canadian FACTs trial by Aneal Khan, Dwayne L. Barber, William M. McKillop, C. Anthony Rupar, Christiane Auray‐Blais, Graeme Fraser, Daniel H. Fowler, Alexandra Berger, Ronan Foley, Armand Keating, Michael L. West, Jeffrey A. Medin

“…Gene‐augmented HSPCs can circulate and thus provide sustained systemic correction. Interim results from this ‘first‐in‐the‐world’ Canadian FACTs (Fabry Disease Clinical Research and Therapeutics) trial were published in 2021. …”
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Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management by Alessio Cecchinato, Hugo Toledo-Alvarado, Lucio Flavio Macedo Mota, Vittoria Bisutti, Erminio Trevisi, Riccardo Negrini, Sara Pegolo, Stefano Schiavon, Luigi Gallo, Giovanni Bittante, Diana Giannuzzi

“…Among factors influencing fertility in dairy cattle, metabolic stress and systemic inflammation of animals are of main relevance, especially in the postpartum stage when ovarian activity begins and cows are inseminated. …”
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ارزیابی امکان‌پذیری تهدید بر دارایی‌های آب و فاضلاب شهری در مواجهه با سوانح انسان‌ساخت عمدی (مطالعه موردی: شهر همدان)... by سعید گیوه چی, علی وجدانی نوذر, بهرام ملک محمدی

“…در این تحقیق باهدف اصلی ارزیابی امکان‌پذیری تهدید بر دارایی‌های آب و فاضلاب شهر همدان در مواجهه با سوانح انسان‌ساخت عمدی، موضوع با استفاده از روش ترکیبی SECA-GIS[1] مورد ارزیابی قرار گرفت، نتایج نشان می‌دهد در این شهر از بین معیارهای ارزیابی تهدیدات؛ شدت تهدید با وزن 1844/0، بزرگی تهدید با وزن 1780/0 و سابقه وقوع با وزن 1674/0 به ترتیب اولویت اول تا سوم را به خود اختصاص داده و همچنین از بین تهدیدات سوانح انسان‌ساخت عمدی به‌طورکلی شورش و اغتشاش رتبه اول، حمله هوایی و موشکی رتبه دوم و خرابکاری رتبه سوم را کسب نموده است، لیکن با نگاهی به دسته‌بندی انواع سوانح انسان‌ساخت عمدی؛ حمله هوایی و موشکی (با عاملیت دشمن خارجی) و شورش و اغتشاشات (با عاملیت دشمن داخلی) در منطقه موردمطالعه در رتبه اول قرار دارند و برحسب جذابیت دارایی‌های زیرساخت آب و فاضلاب از دید دشمن؛ تصفیه‌خانه‌هایآب شهر با کسب امتیاز 5072/4 در سطح بحرانی در مواجهه با حملات هوایی و موشکی قرارگرفته که نیازمند انجام اقدامات پیشگیرانه و دفاعی است. [1] Simultaneous Evaluation of Criteria and Alternatives - Geographic Information System…”
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Mise au point d'un protocole d'évaluation du stress chez les primates captifs et sauvages by Morgane Debuigne, Victor Narat, Baptiste Sadoughi, Michel Saint Jalme, Sabrina Krief

“…Grâce à un travail d'habituation et de training, nous avons pu obtenir des poils facilement et avons pu mettre au point un système de récupération de la salive plusieurs fois par jour. …”
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Dietary Solid-state-fermentation product of Bacillus velezensis T23 alleviate hepatic steatosis, oxidative stress, gut barrier damage, and microbiota dysbiosis in juvenile genetica... by Qiang Hao, Rolf Erik Olsen, Einar Ringø, Qianwen Ding, Tsegay Teame, Yuanyuan Yao, Chao Ran, Yalin Yang, Zhen Zhang, Zhigang Zhou

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Efficacy and safety of everolimus for patients with focal cortical dysplasia type 2 by Se Hee Kim, Hoon‐Chul Kang, Yun Ho Roh, Jongsung Hahn, Kyung Lok Min, Seok‐Jin Lee, Donghwa Yang, Han Som Choi, Soyoung Park, Jeong Ho Lee, Sang‐Guk Lee, Se Hoon Kim, Min Jung Chang, Heung Dong Kim

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Development of an innovative intravaginal model of probiotic inoculation in dairy ovine flocks: positive effects on the vaginal microbiota, vaginitis and fertility by M. Toquet, J. Gomis, E. Jiménez-Trigos, E. Bataller, M. Barba, A. Sánchez, P. González-Torres, Á. Gómez-Martín

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Improving Growth Performance and Reducing Mortality by Supplementing the Ethanolic Extract of Grape Leaves (Vinifera Vitis) in Broilers under Induced Ascites by Mokhtar Fathi, Taimour Tanha, Reza Taherkhani, Vahid Rezaee

“…By reducing the capacity of the body's antioxidant systems, free radicals make the bird susceptible to various diseases. …”
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TRACE Model: Predicting Treatment Response to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma by Wang W, Zhang Q, Cui Y, Zhang S, Li B, Xia T, Song Y, Zhou S, Ye F, Xiao W, Cao K, Chi Y, Qu J, Zhou G, Chen Z, Zhang T, Chen X, Ju S, Wang YC

“…In contrast, none of the published scoring systems, including ART, SNACOR or ABCR score, demonstrated significant differences between the risk groups in OS prediction.Conclusion: The TRACE model exhibited favorable predictive capability for six-month TACE response, and holds potential as a marker for long-term survival outcomes.Keywords: hepatocellular carcinoma, treatment response, transarterial chemoembolization, radiomics…”
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Exploring Future Pandemic Preparedness Through the Development of Preventive Vaccine Platforms and the Key Roles of International Organizations in a Global Health Crisis by Jihee Jeon, Eunyoung Kim

“…As a result, by transforming future pandemic threats from unpredictable crises to surmountable challenges, it is expected to strengthen global health systems and reduce the social and economic burden of emerging infectious diseases in the long term.…”
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Contribution of flood early warning response measures in reducing flood effects in Kilosa District, Tanzania by Japhet Ringo, Shadrack Sabai, Anesi Mahenge

“…The flood early warnings provided are generated and transmitted by local and modern early warning systems (EWS). The responders to these warnings are the people in flood-prone areas at the individual and community (collective) levels, who then have to take voluntary or mandatory measures before and during flood events (onset time). …”
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Potentially commercializable nerve guidance conduits for peripheral nerve injury: Past, present, and future by Chundi Liu, Mouyuan Sun, Lining Lin, Yaxian Luo, Lianjie Peng, Jingyu Zhang, Tao Qiu, Zhichao Liu, Jun Yin, Mengfei Yu

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