Suggested Topics within your search.
Suggested Topics within your search.
- Law 6
- Management 6
- Nursing 6
- methods 6
- Nursing Assessment 5
- Nursing Care 5
- Philosophy 5
- Information technology 4
- Surgical nursing 4
- Anesthesia 3
- Automobiles 3
- Economic conditions 3
- Economic development 3
- Electric power systems 3
- Electronics 3
- Human-computer interaction 3
- Jurisprudence 3
- Management information systems 3
- Microbiology 3
- Nervous System 3
- Neuroanatomy 3
- Pharmaceutical Preparations 3
- Physiology 3
- Politics and government 3
- Telecommunication 3
- administration & dosage 3
- physiology 3
- Anatomy 2
- Cardiovascular system 2
- Cloud computing 2
-
72521
CPEB4 modulates liver cancer progression by translationally regulating hepcidin expression and sensitivity to ferroptosis
Published 2025-03-01“…In mouse models of diet-induced liver cancer (n = 10–15 per group), both systemic and hepatocyte-specific CPEB4 knockout mice exhibited significantly increased tumor burden compared with wild-type controls (p <0.05). …”
Get full text
Article -
72522
Estimation of mangrove carbon stocks using unmanned aerial vehicle over coastal vegetation
Published 2024-07-01“…Drones equipped with multispectral sensors enable the collection of precise and comprehensive data on vegetation and elevation in many ecological systems. The survey and subsequent analysis highlighted the wide variation in the density of mangrove forests in the Lantebung mangrove ecosystem. …”
Get full text
Article -
72523
The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT
Published 2024-06-01“…Scans were performed using three different PET/CT-systems: GE Discovery IQ Gen 2 (USA), Siemens Biograph 64 mCT and Biograph 64 TruePoint (Germany). …”
Get full text
Article -
72524
Does pregabalin offer potential as a first-line therapy for generalized anxiety disorder? A meta-analysis of efficacy, safety, and cost-effectiveness
Published 2025-02-01“…GAD is often underdiagnosed, leading to negative consequences for individuals, healthcare systems, and society. The economic burden and impaired quality of life associated with GAD underscores the need for effective treatment. …”
Get full text
Article -
72525
Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa
Published 2023-11-01“…Therefore, by alleviating burdens on multiple stakeholders, a short regimen is likely to be favourable for rural patients, clinicians, and healthcare systems. Besides other previously described correlates of outcomes, HIV viraemia emerged as a novel marker for reliably predicting poor outcomes in DR-TB with HIV co-infection, and a pragmatic target for intervention. …”
Get full text
Article -
72526
Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration
Published 2025-01-01“…IBU reduced the upregulation of MLKL protein and microglia migration in the ONL and outer plexiform layer (OPL) of treated retinas. Conclusions Systemic administration of the anti-inflammatory drug IBU partially protected mouse retinas from light-induced photochemical damage and inhibited both inflammation and the necroptosis cell death pathways. …”
Get full text
Article -
72527
COVID-19 on patients with immune-mediated rheumatic disease: a comparative study of disease activity, fatigue, and psychological distress over six months
Published 2025-01-01“…Although the mean activity scores did not differ significantly, some patients reported worsened disease activity post-COVID-19, particularly in rheumatoid arthritis (RA) (32.2%) and systemic lupus erythematosus (SLE) patients (23.3%). …”
Get full text
Article -
72528
Influence of spine biomechanics and sagittal balance on the outcome of lumbar discectomy
Published 2025-02-01“…Noteworthy, the radicular and lumbar pain and disability outcomes 12 and 24 months after surgery were significantly better in the group with normal sagittal balance (ODI 14.52 vs. 40.06 p < 0.001; radicular VAS 2.74 vs. 5.58 p < 0.001; lumbar VAS 3.61 vs. 4.06 p < 0.001).ConclusionLumbar degenerative disc disease represents a major burden for healthcare systems; thus, its management is determinant. Lumbar discectomy shows overall positive results, with a significant reduction of pain and disability in the majority of cases. …”
Get full text
Article -
72529
Safety, Tolerability, and Immunogenicity of the Invaplex<sub>AR-Detox</sub> <i>Shigella</i> Vaccine Co-Administered with the dmLT Adjuvant in Dutch and Zambian Adults: Study Protoc...
Published 2025-01-01“…The use of a potent adjuvant enhancing both mucosal and systemic immunity might overcome these problems. Invaplex<sub>AR-Detox</sub> is an injectable Shigella vaccine that uses a novel combination of conserved invasion plasmid antigen proteins and a serotype-specific bacterial lipopolysaccharide attenuated for safe intramuscular administration. …”
Get full text
Article -
72530
Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE
Published 2024-09-01“…APOE also plays key role in lipid metabolism, affecting both peripheral and central systems, particularly in lipoprotein metabolism in triglyceride and cholesterol regulation. …”
Get full text
Article -
72531
Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from...
Published 2025-02-01“…Methods: We conducted a retrospective cohort study of individuals <21 years seeking care at 24 health systems across the U.S, using electronic health record (EHR) data. …”
Get full text
Article -
72532
Atmospheric oxidation of 1,3-butadiene: influence of seed aerosol acidity and relative humidity on SOA composition and the production of air toxic compounds
Published 2025-01-01“…The photochemical reactivity of 13BD in our systems decreased with increasing RH and was faster under non-acidified than acidified seed conditions. …”
Get full text
Article -
72533
Post-acute sequelae of hospitalised COVID-19 re-infection compared with hospitalised first-time infection: a population-based retrospective cohort study in Hong Kong
Published 2025-01-01“…Introduction COVID-19 infection is associated with post-acute adverse outcomes affecting multiple organ systems. Although preliminary studies have suggested that COVID-19 re-infection may have a cumulative effect on long-term outcome, differential effects of COVID-19 re-infection severe enough to be hospitalised on post-acute sequelae compared with hospitalised first-time infection have not been explored.Methods Retrospective cohort study using territory-wide electronic medical records databases in Hong Kong. …”
Get full text
Article -
72534
High-risk human papillomavirus: prevalence, association with clinical and morphological characteristics of invasive cervical cancer
Published 2023-12-01“…Ambiguous conclusions on the presence of an association between a number of molecular-genetic parameters of HPV infection with the main prognostic factor – stage of the disease (due to the heterogeneity of samples, the use of different test systems, and the insufficiently complete account of the main parameters of HPV infection, especially data on viral DNA integration), make it advisable to conduct further research on a representative group of patients with homogeneous diagnostic protocols to determine the most complete spectrum of parameters of high oncogenic risk HPV. …”
Get full text
Article -
72535
Towards person-centred maternal and newborn care in Ethiopia: a mixed method study of satisfaction and experiences of care
Published 2025-01-01“…Triangulation of findings indicated a mismatch between what women valued about care, their reported satisfaction with care and the actual care they were observed to receive. Conclusions Systems strengthening interventions to support person-centred maternal care appear contextually relevant but need to increase women’s expectations of care and agency to demand change. …”
Get full text
Article -
72536
Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes: protocol for a nati...
Published 2025-01-01“…Sodium-glucose transport protein 2 inhibitors (SGLT-2i) will be excluded as comparators, as this class of oral hypoglycaemic agents just started in 2020 to be marketed in France.Methods and analysis The Système National des Données de Santé is a comprehensive nationwide administrative healthcare database in France that covers approximately 67 million people.Several cohorts of adult patients with T2D initiating any GLP1-RA in dual or triple therapies, as recommended by the French Health authorities, will be identified in this database over the period 2016–2021. …”
Get full text
Article -
72537
Land use changes, green house gas emissions, and rehabilitation model of native tree species towards sustainable management
Published 2024-10-01“…Peatlands serve as efficient carbon storage systems in a consistent climate, however, they are vulnerable to alterations. …”
Get full text
Article -
72538
First-in-human phase I trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein, SL-172154 in patients with platinum-resistant ovarian cancer
Published 2025-01-01“…Objectives included evaluation of safety, dose-limiting toxicity, recommended phase II dose, pharmacokinetic (PK) and pharmacodynamic (PD) parameters, and antitumor activity.Results 27 patients (median age 66 years (range, 33–85); median of 4 prior systemic therapies (range, 2–9)) with ovarian (70%), fallopian tube (15%), or primary peritoneal (15%) cancer received SL-172154. …”
Get full text
Article -
72539
Effet de l'illumination proche infra-rouge intracérébrale chez des primates MPTP
Published 2015-03-01“…La maladie de Parkinson (MP) est une maladie neurodégénérative chronique affectant le système dopaminergique et se traduisant par une perte des neurones dopaminergiques (DA) de la substance noire compacta (SNc) et des faisceaux nigro-striés. …”
Get full text
Article -
72540
Effectiveness of Electronic Quality Improvement Activities to Reduce Cardiovascular Disease Risk in People With Chronic Kidney Disease in General Practice: Cluster Randomized Trial...
Published 2025-02-01“… BackgroundFuture Health Today (FHT) is a program integrated with electronic medical record (EMR) systems in general practice and comprises (1) a practice dashboard to identify people at risk of, or with, chronic disease who may benefit from intervention; (2) active clinical decision support (CDS) at the point of care; and (3) quality improvement activities. …”
Get full text
Article