Deep-learning prediction of cardiovascular outcomes from routine retinal images in individuals with type 2 diabetes by Mohammad Ghouse Syed, Emanuele Trucco, Muthu R. K. Mookiah, Chim C. Lang, Rory J. McCrimmon, Colin N. A. Palmer, Ewan R. Pearson, Alex S. F. Doney, Ify R. Mordi

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Conglomerated Imiquimod and Metronidazole Incorporated Biodegradable Nanofibrous Mats for Potential Therapy of Cervical Cancer by Chen YP, Chiu CF, Wang CN, Lin CC, Shen CR, Yao YC, Kuo YH, Liu SJ

“…In vivo, each membrane consistently released elevated concentrations of imiquimod/metronidazole at the intended site in mice over a four-week period, with minimal systemic drug concentration detected in the bloodstream. …”
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Silk Protein Gene Engineering and Its Applications: Recent Advances in Biomedicine Driven by Molecular Biotechnology by Ji X, Li Y, Wang J, Wang G, Ma B, Shi J, Cui C, Wang R

“…By analyzing the genetic factors influencing silk protein expression, this review further elaborates on the innovative applications of silk proteins in drug delivery systems, tissue engineering and regenerative medicine (eg, skin, bone, cartilage, and vascular repair), as well as antibacterial immune strategies. …”
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The Model of Disengagement of Talent with Meta-synthesis Method by Ali Asghar Mobasheri, Ali Nasr Isfahani, Hadi Teimouri

“…The organizational factors were categorized into five components: job-related factors (such as lack of autonomy, high work stress, lack of job security, insufficient feedback, mismatch between competencies and duties, and limited growth opportunities), cultural factors (inappropriate work environment, prevalence of bullying, political behaviors, individualism, melting pot mentality, and nepotism), structural factors (high formality, bureaucratic structures, centralized decision-making, and structural differentiation), managerial factors (managerial incompetence, Machiavellian tendencies, resistance to criticism, narcissism, and excessive focus on work), and process-related factors (weak compensation systems, poor communication processes, ineffective performance management, and inadequate talent management and succession planning). …”
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Technologies for Interoperable Internet of Medical Things Platforms to Manage Medical Emergencies in Home and Prehospital Care: Scoping Review by Mattias Seth, Hoor Jalo, Åsa Högstedt, Otto Medin, Bengt Arne Sjöqvist, Stefan Candefjord

“… BackgroundThe aging global population and the rising prevalence of chronic disease and multimorbidity have strained health care systems, driving the need for expanded health care resources. …”
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Buffalo genetic improvement program in Vene- zuela by José A. Aranguren-Méndez, Rafael M. Román-Bravo, Ricardo A. Briceño-Rojas, Mauricio G. Briceño-Rojas, Luis A. Pacheco-Díaz

“…This index allows for jointly selecting both important characteristics in buffalo production systems. Moreover, in the American tropics, the crossing of Murrah with the Mediterranean buffalo breed should be avoided since both breeds have a good adaptation to the environment and excellent production levels, which is why an absorption program for the pure breed is recommended in programs for individuals of each breed. …”
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A Multifunctional MIL-101-NH2(Fe) Nanoplatform for Synergistic Melanoma Therapy by Shang J, Chen Y, Wang F, Yang J, Li Y, Yang L, Liu X, Zhong Z, Yue C, Zhou M

“…In vivo experiments in melanoma-bearing mice evaluated antitumor efficacy and systemic safety through tumor growth inhibition, histological analyses, and toxicity assessments.Results: MIL@DOX@ICG exhibited a uniform octahedral structure with a particle size of approximately 139 nm and high drug loading efficiencies for DOX (33.70%) and ICG (30.59%). …”
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The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis by Zhihui Xu, Cong Liu, Peng Wang, Xing Wang, Yuzhang Li

“…Conclusion Based on the International Classification of Diseases (ICD) and the Diagnostic and Statistical Manual of Mental Disorders (DSM) classification systems, a research framework for exercise interventions on executive function in MDD patients was constructed, demonstrating that exercise can improve inhibitory function in MDD with high evidence quality. …”
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Intermediate pyrolysis of Ficus nitida wood in a fixed-bed reactor: effect of pyrolysis parameters on bio-oil and bio-char yields and properties by Tabal, Amine, Belyazid, Oumayma, Dahman, Hicham, Berrich, Emna, Jeguirim, Mejdi, El Achaby, Mounir, El Harfi, Khalifa, Aboulkas, Adil

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Serum IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, IL-2, and IL-6 in Insulin-Dependent Diabetic Children

“…Our data about elevated serum IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math> and decreased IL-2, IL-6 levels in newly diagnosed IDDM patients in comparison with longer standing cases supports an activation of systemic inflammatory process during early phases of IDDM which may be indicative of an ongoing <mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>-cell destruction. …”
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Comparison of Ultrasound Energy Delivered to the Anterior Segment Across Different Phacoemulsification Surgical Platforms by Nelson TK, Ricks RG, Cardenas IA, Whitaker T, Jensen JL, Olson RJ, Pettey JH

“…Three phacoemulsification systems were compared: the Alcon Centurion, Johnson & Johnson Veritas and Oertli CataRhex 3. …”
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Whole-genome sequencing and metagenomics reveal diversity and prevalence of Listeria spp. from soil in the Nantahala National Forest by Jia Wang, Claire N. Schamp, Lauren K. Hudson, Harleen K. Chaggar, Daniel W. Bryan, Katie N. Garman, Mark Radosevich, Thomas G. Denes

“…This study also highlights the potential for integrating metagenomics into routine surveillance systems for food safety in the near future.…”
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Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma by Limin Zhou, Jiejie Liu, Peipei Yao, Xing Liu, Fei Chen, Yu Chen, Li Zhou, Chao Shen, You Zhou, Xin Du, Junbo Hu

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Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress by Saakshi Saini, Viney Kumar, Swati Haldar, Samrat Chauhan, Pratibha Demiwal, Souvik Ghosh, Sumeet Gupta, Debabrata Sircar, Bidhan Mahajon, Partha Roy

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Enhancing environmental decontamination and sustainable production through synergistic and complementary interactions of actinobacteria and fungi by Juliana M. Saez, Enzo E. Raimondo, Stefanie B. Costa-Gutierrez, Juan D. Aparicio, Domenica Mosca Angelucci, Enrica Donati, Marta A. Polti, Maria C. Tomei, Claudia S. Benimeli

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Functional tests in children with type 1 diabetes and their correlation with hemoglobin A1c levels by V.R. Abdulina, I.S. Stepanova

“…Ocular biometry, CCT, and CMT measurements are useful tests illustrating the level of compensation of systemic disease. Dynamic assessment of these parameters will help develop indicators of diabetic retinopathy in children with T1D.…”
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An assessment of the progress made in the implementation of the regional framework for cholera prevention and control in the WHO African region by Miriam Nanyunja, Allan Mpairwe, Ibrahim Mamadu, Otim Patrick Cossy Ramadan, Mory Keïta, Tamayi Mlanda, Abdou Salam Gueye, Ebenezer Obi Daniel, Etien Luc Koua, Dick Chamla, Fiona Braka, Fred Kapaya, Vincent Dossou Sodjinou, Godwin Akpan, Shikanga O-tipo, Amarachi Tikal Abianuru, John Masina, Alice Igale Ladu, Fred Athanasius Dratibi, Philippe Barboza

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Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis by Shuning Guo, Jiehan Li, Shurui Pang, Jing Li, Xinping Tian

“…Abstract Background Advances in treatment have swiftly alleviated systemic inflammation of Takayasu’s arteritis (TAK), while subclinical vascular inflammation and the ensuing arterial remodeling continue to present unresolved challenges in TAK. …”
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YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution by Farhoud Faraji, Sydney I. Ramirez, Lauren M. Clubb, Kuniaki Sato, Valeria Burghi, Thomas S. Hoang, Adam Officer, Paola Y. Anguiano Quiroz, William M. G. Galloway, Zbigniew Mikulski, Kate Medetgul-Ernar, Pauline Marangoni, Kyle B. Jones, Yuwei Cao, Alfredo A. Molinolo, Kenneth Kim, Kanako Sakaguchi, Joseph A. Califano, Quinton Smith, Alon Goren, Ophir D. Klein, Pablo Tamayo, J. Silvio Gutkind

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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…PROC patients with multiple recurrences are unable to continue highly toxic treatment after prior multiple lines of systemic therapy. Chemotherapy-free option lenvatinib plus anti-programmed cell death protein-1 (PD-1) combination therapy has shown promising results in several malignancies including ovarian cancer, but the toxicity of a high starting dose of lenvatinib is also notable and needs to be improved. …”
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