“Subtype-precise” therapy leads diagnostic and therapeutic innovations: a new pattern for precision treatment of breast cancer by ZHANG Siwei, MA Ding, JIANG Yizhou, SHAO Zhimin

“…The treatment of breast cancer has undergone significant transformations, evolving from an initial reliance on a single surgical approach to the incorporation of systemic therapy, and more recently, to subtype-specific therapy. …”
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Prolonged pain-to-balloon time still impairs midterm left ventricular function following STEMI by Dominik Felbel, Sabrina Fackler, Rachel Michalke, Michael Paukovitsch, Matthias Gröger, Mirjam Keßler, Nicoleta Nita, Yannick Teumer, Leonhard Schneider, Armin Imhof, Dominik Buckert, Wolfgang Rottbauer, Sinisa Markovic

“…Further improvements in healthcare systems and public education are essential to reduce treatment delays and improve long-term outcomes.…”
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The Innovation Intermediaries Role in the Adoption of Emerging Technologies in Iran's Automotive Industry by Ali Maleki, Hadi Nilforoushan

“…Over the last two decades, scientific research has notably focused on the adoption of theories of emerging technologies within information and industrial systems. Innovation intermediaries are organizations or bodies that act as representatives or agents in every aspect of the innovation process between two parties and are recognized as important actors that can facilitate the innovation process. …”
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Experimental identification of I-mode characteristics at the edge of FIRE mode in KSTAR by Chweeho Heo, SangJin Park, GyungJin Choi, Jaewook Kim, Eun-jin Kim, YoungMu Jeon, Minjun J. Choi, Hyunsun Han, Choongki Sung, TaikSoo Hahm, Yong-Su Na

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Identifying community-driven priority questions in acoustic backscatter research by Vincent Lecours, Benjamin Misiuk, Benjamin Misiuk, Felix Butschek, Felix Butschek, Philippe Blondel, Giacomo Montereale-Gavazzi, Vanessa L. Lucieer, Chris McGonigle

“…The two questions that were identified as priorities by over 25% of respondents were “How can we move towards absolute calibration of different systems to allow interregional comparisons?”, and “How can we quantify seafloor backscatter quality and develop standards similar to what exists with bathymetry?”.…”
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Health Services Availability and Readiness for Management of Hypertension and Diabetes in Primary Care Health Facilities in Ghana: a Cardiovascular Risk Management project by Thomas Hinneh, Bernard Mensah, Hosea Boakye, Oluwabunmi Ogungbe, Yvonne Commodore-Mensah

“…This study explored service availability and readiness of health systems for managing hypertension and diabetes in selected district hospitals in Ghana. …”
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Glaucoma progression during the COVID-19 pandemics by V.E. Korelina, I.R. Gazizova, A.V. Kuroyedov, M.D. Didur

“…The property of this virus to initiate disseminated intravascular coagulation, damage endotheliocytes, and impair coagulation result in numerous severe complications affecting all organs and systems. This disorder provokes retinal ischemia and hypoxia and spurs apoptosis of ganglionic cells. …”
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Characterization of Enterobacterales growing on selective CPE screening plates with a focus on non-carbapenemase-producing strains by Reut Efrati Epchtien, Elizabeth Temkin, Mor N. Lurie-Weinberger, Ophir Kastel, Alona Keren-Paz, David Schwartz, Yehuda Carmeli

“…Species identification and antibiotic susceptibility testing were performed using VITEK systems. Further analyses focused on Klebsiella pneumoniae and Escherichia coli which were the most common isolates. …”
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Une double discordance cardiaque complexe décompensée, à propos d’un cas et revue de la littérature by Nabila Soufi Taleb Bendiab, Rachid Djaziri, Fouad Sekkal, Nesrine Khedim, Abderrahim Meziane-Tani

“…Its prognosis depends mainly on other associated congenital heart defects, arrhythmias and disorders of the conduction, as well as systolic function of the right ventricle in the systemic position. We report the case of a 23-year-old patient with a complex cyanogen heart disease. …”
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Advancing cancer therapy with custom-built alternating electric field devices by Isobel Jobson, Nguyen T. N. Vo, Edward Kujawinski, Chris Denning, Snow Stolnik, Veeren M. Chauhan, Frankie Rawson

“…However, there is a space to design alternative systems that will be amenable for wider use in current research. …”
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Linear Programming as a Tool for Managing the Training Process of Esports Teams by Oksana Shynkaruk, Nataliia Byshevets, Alla Aloshyna, Olena Iakovenko, Kostiantyn Serhiienko, Valerii Pinchuk, Oleksandr Petryk, Ivan Lut

“…The proposed approach can serve as a foundation for creating more advanced systems for managing the training process. Future research prospects include expanding the functionality of linear programming by incorporating additional factors such as psychological aspects, social dynamics within the team, and the physiological indicators of athletes. …”
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Bi-level data-driven enterprise-wide optimization with mixed-integer nonlinear scheduling problems by Hasan Nikkhah, Zahir Aghayev, Amir Shahbazi, Vassilis M. Charitopoulos, Styliani Avraamidou, Burcu Beykal

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PD(L)1 Inhibitors Plus Lenvatinib Vs Atezolizumab Plus Bevacizumab Combined With HAIC for Unresectable HCC: A Propensity Score Matching Study by He Z, Chen H, Liang C, Tang X, Jiang L, Xie F, Liu Q, Zheng Y

“…Zhaoqian He,1– 3,* Hua Chen,1– 3,* Chen Liang,1– 3,* Xiang Tang,1– 3 Lingmin Jiang,1– 3 Feihu Xie,1– 3 Qi Liu,1– 3 Yun Zheng1– 3 1Department of Liver Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China; 2Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China; 3Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, 510060, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yun Zheng; Qi Liu, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, People’s Republic of China, Email zhengyun@sysucc.org.cn; liuqi9@sysucc.org.cnPurpose: To compare the clinical outcomes of different systemic therapies, specifically PD(L)1 inhibitors plus Lenvatinib versus Atezolizumab plus Bevacizumab, when combined with hepatic arterial infusion chemotherapy (HAIC) based on the FOLFOX regimen (oxaliplatin, fluorouracil, and leucovorin) as first line treatment for unresectable hepatocellular carcinoma.Patients and Methods: This real-world retrospective study enrolled 294 patients with unresectable HCC. …”
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Nomogram model and risk score predicting overall survival and guiding clinical decision in patients with Hodgkin’s lymphoma: an observational study using SEER population-based data... by Yue Yang, Shang Li, Xiao Zhu, Yi Kong, Mingtao Zhang, Xiangping Liang, Zherui Zhang, Shuzhen Tan, Yingqi Li, Yueyuan Zhong, Yingqi Shao, Jiayi Xu, Zesong Li

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Probing Quantum Telecloning on Superconducting Quantum Processors by Elijah Pelofske, Andreas Bartschi, Stephan Eidenbenz, Bryan Garcia, Boris Kiefer

“…We present universal symmetric optimal <inline-formula><tex-math notation="LaTeX">$1 \rightarrow M$</tex-math></inline-formula> telecloning circuits and experimentally demonstrate these quantum telecloning circuits for <inline-formula><tex-math notation="LaTeX">$M=2$</tex-math></inline-formula> up to <inline-formula><tex-math notation="LaTeX">$M=10$</tex-math></inline-formula>, natively executed with real-time classical control systems on IBM Quantum superconducting processors, known as dynamic circuits. …”
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Soil organic carbon and related properties under conservation agriculture and contrasting conventional fields in Northern Malawi by Muneta G. Manzeke-Kangara, Ivy S. Ligowe, Austin Tibu, Timothy N. Gondwe, Henry M. R. Greathead, Marcelo V. Galdos, Marcelo V. Galdos

“…However, challenges of competing residue use as feed, mulch, and fuel continue to impede mulching under CA systems. Longer term studies and use of alternative mulching options could be employed to recognise noticeable changes in other SOC beneficial pools in fields under CA.…”
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Effect of Nasal Obstructive Disorders on Sinonasal Symptoms in Children with Different Levels of Bronchial Asthma Control by T. I. Eliseeva, S. V. Krasilnikova, N. A. Geppe, S. Yu. Babaev, E. V. Tush, O. V. Khaletskaya, D. Yu. Ovsyannikov, I. I. Balabolkin, S. K. Ignatov, N. I. Kubysheva

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Emerging Implications of Serum Resolvin D2 as a Biochemical Marker for Severity Assessment and Prognosis Prediction Following Moderate-Severe Traumatic Brain Injury: A Prospective... by Zong H, Zong Y, Li J, Zhao S, Wu W, Chen R, Zhao G, Li Z

“…The severity scoring systems encompassed the Rotterdam computed tomography classification and Glasgow Coma Scale (GCS). …”
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Multimodal Pain Recognition in Postoperative Patients: Machine Learning Approach by Ajan Subramanian, Rui Cao, Emad Kasaeyan Naeini, Seyed Amir Hossein Aqajari, Thomas D Hughes, Michael-David Calderon, Kai Zheng, Nikil Dutt, Pasi Liljeberg, Sanna Salanterä, Ariana M Nelson, Amir M Rahmani

“…Multimodal pain assessment, integrating physiological and behavioral data, presents an opportunity to create more objective and accurate pain measurement systems. However, most previous work has focused on healthy subjects in controlled environments, with limited attention to real-world postoperative pain scenarios. …”
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Prospects for the use of a <i>Bacillus subtilis</i> metabolites-based feed additive in dairy farming by S. V. Malkov, A. S. Krasnoperov, A. P. Poryvaeva, O. Yu. Oparina, A. I. Belousov, A. N. Brilliant

“…The feed additive impact on main body systems of the tested cows (n = 30), milk production parameters, growth rate of the calves (n = 18) born to the said cows were examined. …”
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